{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:06:51Z","timestamp":1777482411429,"version":"3.51.4"},"reference-count":62,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.expneurol.2011.07.008","type":"journal-article","created":{"date-parts":[[2011,8,2]],"date-time":"2011-08-02T04:54:33Z","timestamp":1312260873000},"page":"22-32","source":"Crossref","is-referenced-by-count":16,"title":["Relationship between sensorimotor gating deficits and dopaminergic neuroanatomy in Nurr1-deficient mice"],"prefix":"10.1016","volume":"232","author":[{"given":"St\u00e9phanie","family":"Vuillermot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joram","family":"Feldon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Urs","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.expneurol.2011.07.008_bb0005","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0166-4328(03)00029-9","article-title":"Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine","volume":"143","author":"B\u00e4ckman","year":"2003","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0010","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1111\/j.1471-4159.1977.tb07780.x","article-title":"Correlation between tyrosine hydroxylase activity and catecholamine concentration or turnover in brain regions","volume":"29","author":"Bacopoulos","year":"1977","journal-title":"J. Neurochem."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0015","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.tins.2007.03.006","article-title":"Dopamine neuron systems in the brain: an update","volume":"30","author":"Bj\u00f6rklund","year":"2007","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0020","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1007\/s002130100810","article-title":"Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies","volume":"156","author":"Braff","year":"2001","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0025","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1002\/1096-8628(20001204)96:6<808::AID-AJMG23>3.0.CO;2-E","article-title":"Nurr1 mutations in cases of schizophrenia and manic\u2013depressive disorder","volume":"96","author":"Buervenich","year":"2000","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0030","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.bbadis.2009.11.005","article-title":"Recent advances in the manipulation of murine gene expression and its utility for the study of human neurological disease","volume":"1802","author":"Cazzin","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0035","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/cne.20828","article-title":"Nurr1 in Parkinson's disease and related disorders","volume":"494","author":"Chu","year":"2006","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0040","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/schbul\/sbm146","article-title":"Impaired prepulse inhibition and prepulse-elicited reactivity but intact reflex circuit excitability in unmedicated schizophrenia patients: a comparison with healthy subjects and medicated schizophrenia patients","volume":"35","author":"Csomor","year":"2009","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0045","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.euroneuro.2007.02.005","article-title":"Risk factors for schizophrenia\u2014all roads lead to dopamine","volume":"17","author":"Di Forti","year":"2007","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0050","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0166-4328(02)00185-7","article-title":"Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity","volume":"136","author":"Eells","year":"2002","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0055","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.neuroscience.2005.12.065","article-title":"Early postnatal isolation reduces dopamine levels, elevates dopamine turnover and specifically disrupts prepulse inhibition in Nurr1-null heterozygous mice","volume":"140","author":"Eells","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0060","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.brainresbull.2006.05.004","article-title":"Reduced tyrosine hydroxylase and GTP cyclohydrolase mRNA expression, tyrosine hydroxylase activity, and associated neurochemical alterations in Nurr1-null heterozygous mice","volume":"70","author":"Eells","year":"2006","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0065","series-title":"The Mouse Brain in Stereotaxic coordinates","author":"Franklin","year":"2008"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0167-8760(01)00195-7","article-title":"Impaired attention modulation of the blink reflex R3 component in Parkinson's disease: a non-task warning paradigm study","volume":"44","author":"Gabrielli","year":"2002","journal-title":"Int. J. Psychophysiol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0075","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1469-8986.1975.tb01284.x","article-title":"The more or less startling effects of weak prestimulation","volume":"12","author":"Graham","year":"1975","journal-title":"Psychophysiology"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0080","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1002\/mds.20820","article-title":"Translated mutation in the Nurr1 gene as a cause for Parkinson's disease","volume":"21","author":"Grimes","year":"2006","journal-title":"Mov. Disord."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0074-7742(06)78001-1","article-title":"Neurobiology of dopamine in schizophrenia","volume":"78","author":"Guillin","year":"2007","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0090","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1111\/j.1699-0463.1988.tb00954.x","article-title":"The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis","volume":"96","author":"Gundersen","year":"1988","journal-title":"APMIS"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0095","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1037\/h0022325","article-title":"Acoustic variables in the modification of startle reaction in the rat","volume":"60","author":"Hoffman","year":"1965","journal-title":"J. Comp. Physiol. Psychol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0100","series-title":"Unbiased Stereology","author":"Howard","year":"2005"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0105","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/schbul\/sbp006","article-title":"The dopamine hypothesis of schizophrenia: version III\u2014the final common pathway","volume":"35","author":"Howes","year":"2009","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0110","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1192\/bjp.191.51.s13","article-title":"Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis","volume":"51","author":"Howes","year":"2007","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0115","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.brainresrev.2004.04.007","article-title":"Genetic contributions to Parkinson's disease","volume":"46","author":"Huang","year":"2004","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0120","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.pneurobio.2005.09.001","article-title":"The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease","volume":"77","author":"Jankovic","year":"2005","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0125","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.expneurol.2004.08.035","article-title":"Age-dependent dopaminergic dysfunction in Nurr1 knockout mice","volume":"191","author":"Jiang","year":"2005","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0130","doi-asserted-by":"crossref","first-page":"15923","DOI":"10.1523\/JNEUROSCI.3910-09.2009","article-title":"Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons","volume":"29","author":"Kadkhodaei","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0135","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/brain\/96.1.87","article-title":"Disorder of interneurons in Parkinsonism. The orbicularis oculi reflex to paired stimuli","volume":"96","author":"Kimura","year":"1973","journal-title":"Brain"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0140","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0166-4328(00)00299-0","article-title":"Role of the substantia nigra pars reticulata in sensorimotor gating, measured by prepulse inhibition of startle in rats","volume":"117","author":"Koch","year":"2000","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb1000","first-page":"211","article-title":"Imaging dopamine transmission in schizophrenia. A review and meta-analysis","volume":"42","author":"Laruelle","year":"1998","journal-title":"Q. J. Nucl. Med."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0145","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1006\/exnr.1999.7191","article-title":"Selective agenesis of mesencephalic DA neurons in Nurr1-deficient mice","volume":"159","author":"Le","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0150","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/BF01291885","article-title":"Functional changes of brainstem reflexes in Parkinson's disease. Conditioning of the blink reflex R2 component by paired and index finger stimulation","volume":"104","author":"Lozza","year":"1997","journal-title":"J. Neural. Transm."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0155","doi-asserted-by":"crossref","first-page":"e15193","DOI":"10.1371\/journal.pone.0015193","article-title":"Decreased level of Nurr1 in heterozygous young adult mice leads to exacerbated acute and long-term toxicity after repeated methamphetamine exposure","volume":"5","author":"Luo","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0160","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/BF00212846","article-title":"Dopaminergic stimulation disrupts sensorimotor gating in the rat","volume":"94","author":"Mansbach","year":"1988","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0165","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1046\/j.1460-9568.1999.00540.x","article-title":"Unexpected localization of the Na+\/Cl\u2212 dependent-like orphan transporter, Rxt1, on synaptic vesicles in the rat central nervous system","volume":"11","author":"Masson","year":"1999","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0170","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.neubiorev.2004.10.012","article-title":"Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia","volume":"29","author":"Meyer","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0175","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/sj.npp.1301413","article-title":"Relative prenatal and postnatal maternal contributions to schizophrenia-related neurochemical dysfunction after in utero immune challenge","volume":"33","author":"Meyer","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0180","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/0168-5597(93)90092-4","article-title":"Auditory effects on the electrically elicited blink reflex in patients with Parkinson's disease","volume":"89","author":"Nakashima","year":"1993","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0185","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.bbr.2009.04.021","article-title":"Prepulse inhibition and genetic mouse models of schizophrenia","volume":"204","author":"Powell","year":"2009","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0190","doi-asserted-by":"crossref","first-page":"4627","DOI":"10.1523\/JNEUROSCI.19-11-04627.1999","article-title":"The dopamine d2, but not d3 or d4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice","volume":"19","author":"Ralph","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0195","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1523\/JNEUROSCI.21-01-00305.2001","article-title":"Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists","volume":"21","author":"Ralph","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0200","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/sj.npp.1300017","article-title":"Dopamine D1 rather than D2 receptor agonists disrupt prepulse inhibition of startle in mice","volume":"28","author":"Ralph-Williams","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0205","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/syn.20623","article-title":"Dopaminergic synapses in the caudate of subjects with schizophrenia: relationship to treatment response","volume":"63","author":"Roberts","year":"2009","journal-title":"Synapse"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0210","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/sj.mp.4001993","article-title":"Adult mice with reduced Nurr1 expression: an animal model for schizophrenia","volume":"12","author":"Rojas","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0215","doi-asserted-by":"crossref","first-page":"2284","DOI":"10.1002\/jnr.22377","article-title":"Rapid increase of Nurr1 mRNA expression in limbic and cortical brain structures related to coping with depression-like behavior in mice","volume":"88","author":"Rojas","year":"2010","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0220","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.cell.2009.01.038","article-title":"A Nurr1\/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death","volume":"137","author":"Saijo","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0225","doi-asserted-by":"crossref","first-page":"4013","DOI":"10.1073\/pnas.95.7.4013","article-title":"Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons","volume":"95","author":"Saucedo-Cardenas","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0230","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/nrn2039","article-title":"How to make a mesodiencephalic dopaminergic neuron","volume":"8","author":"Smidt","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0235","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/0006-3223(93)90300-3","article-title":"A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder","volume":"33","author":"Swerdlow","year":"1993","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0240","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1136\/jnnp.58.2.192","article-title":"Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease","volume":"58","author":"Swerdlow","year":"1995","journal-title":"Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0245","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s002130100799","article-title":"Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges","volume":"156","author":"Swerdlow","year":"2001","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0250","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1600-0447.1988.tb06312.x","article-title":"Neurotransmitters, receptors and neuropeptides in postmortem brains of chronic schizophrenic patients","volume":"78","author":"Toru","year":"1988","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0255","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.pneurobio.2008.01.003","article-title":"Getting connected in the dopamine system","volume":"85","author":"Van den Heuvel","year":"2008","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0260","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1523\/JNEUROSCI.5408-09.2010","article-title":"A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia","volume":"30","author":"Vuillermot","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0265","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1601-183X.2011.00698.x","article-title":"Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency","volume":"10","author":"Vuillermot","year":"2011","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0270","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1006\/excr.1999.4691","article-title":"Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice","volume":"253","author":"Wall\u00e9n","year":"1999","journal-title":"Exp. Cell. Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0275","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0091-3057(94)90470-7","article-title":"Accumbens D2 modulation of sensorimotor gating in rats: assessing anatomical localization","volume":"49","author":"Wan","year":"1994","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0280","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/BF02245815","article-title":"Presynaptic dopamine\u2013glutamate interactions in the nucleus accumbens regulate sensorimotor gating","volume":"120","author":"Wan","year":"1995","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0285","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0169-328X(00)00211-4","article-title":"Nigrostriatal innervation is preserved in Nurr1-null mice, although dopaminergic neuron precursors are arrested from terminal differentiation","volume":"84","author":"Witta","year":"2000","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0290","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.schres.2005.11.006","article-title":"Reduction of dopamine-related transcription factors Nurr1 and NGFI-B in the prefrontal cortex in schizophrenia and bipolar disorders","volume":"84","author":"Xing","year":"2006","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0295","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1038\/sj.npp.1300480","article-title":"The effects of dizocilpine and phencyclidine on prepulse inhibition of the acoustic startle reflex and on prepulse-elicited reactivity in C57BL6 mice","volume":"29","author":"Yee","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.expneurol.2011.07.008_bb0300","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0169-328X(96)00074-5","article-title":"Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system","volume":"41","author":"Zetterstr\u00f6m","year":"1996","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.expneurol.2011.07.008_bb0305","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1126\/science.276.5310.248","article-title":"Dopamine neuron agenesis in Nurr1-deficient mice","volume":"276","author":"Zetterstr\u00f6m","year":"1997","journal-title":"Science"}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488611002627?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488611002627?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T13:24:24Z","timestamp":1560432264000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488611002627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":62,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0014488611002627"],"URL":"https:\/\/doi.org\/10.1016\/j.expneurol.2011.07.008","relation":{},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}