{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:50:08Z","timestamp":1793163008909,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["P01 NS082184-01"],"award-info":[{"award-number":["P01 NS082184-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.expneurol.2016.06.010","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T22:14:02Z","timestamp":1466115242000},"page":"157-164","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"special_numbering":"PA","title":["Role of PDGF-D and PDGFR-\u03b2 in neuroinflammation in experimental ICH mice model"],"prefix":"10.1016","volume":"283","author":[{"given":"Peng","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anatol","family":"Manaenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyan","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaiqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuezhen","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Ni","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Hartman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Pearce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Obenaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiping","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.expneurol.2016.06.010_bb0005","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1101\/gad.1653708","article-title":"Role of platelet-derived growth factors in physiology and medicine","volume":"22","author":"Andrae","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0010","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1742-2094-9-26","article-title":"A functional variant in promoter region of platelet-derived growth factor-D is probably associated with intracerebral hemorrhage","volume":"9","author":"Bai","year":"2012","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.expneurol.2016.06.010_bb0015","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/35074588","article-title":"PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor","volume":"3","author":"Bergsten","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0020","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1186\/1742-2094-9-262","article-title":"Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation","volume":"9","author":"Bethel-Brown","year":"2012","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.expneurol.2016.06.010_bb0025","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.bbrc.2014.12.106","article-title":"Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities","volume":"457","author":"Borkham-Kamphorst","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0030","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.intimp.2013.06.015","article-title":"Neutrophils and stroke - can neutrophils mitigate disease in the central nervous system?","volume":"17","author":"Easton","year":"2013","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0035","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.cytogfr.2004.03.007","article-title":"The PDGF family: four gene products form five dimeric isoforms","volume":"15","author":"Fredriksson","year":"2004","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0040","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/cvr\/cvp184","article-title":"Urokinase activates macrophage PON2 gene transcription via the PI3K\/ROS\/MEK\/SREBP-2 signalling cascade mediated by the PDGFR-beta","volume":"84","author":"Fuhrman","year":"2009","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0045","doi-asserted-by":"crossref","first-page":"3901","DOI":"10.1523\/JNEUROSCI.4070-13.2014","article-title":"CCR2+ Ly6C(hi) inflammatory monocyte recruitment exacerbates acute disability following intracerebral hemorrhage","volume":"34","author":"Hammond","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0050","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1152\/physrev.1999.79.4.1283","article-title":"Mechanism of action and in vivo role of platelet-derived growth factor","volume":"79","author":"Heldin","year":"1999","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0055","doi-asserted-by":"crossref","first-page":"24353","DOI":"10.1016\/S0021-9258(20)80533-X","article-title":"Expression of platelet-derived growth factor beta receptor on human monocyte-derived macrophages and effects of platelet-derived growth factor BB dimer on the cellular function","volume":"268","author":"Inaba","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0060","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.bbr.2014.01.052","article-title":"Correlation between subacute sensorimotor deficits and brain edema in two mouse models of intracerebral hemorrhage","volume":"264","author":"Krafft","year":"2014","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0065","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/35074593","article-title":"PDGF-D, a new protease-activated growth factor","volume":"3","author":"LaRochelle","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0070","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1007\/s12975-012-0151-3","article-title":"Age-related comparisons of evolution of the inflammatory response after intracerebral hemorrhage in rats","volume":"3","author":"Lively","year":"2012","journal-title":"Translational Stroke Research"},{"key":"10.1016\/j.expneurol.2016.06.010_bb0075","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1002\/ana.22549","article-title":"PDGFR-alpha inhibition preserves blood-brain barrier after intracerebral hemorrhage","volume":"70","author":"Ma","year":"2011","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0080","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.neuint.2010.09.001","article-title":"Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage","volume":"57","author":"Manaenko","year":"2010","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0085","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.neuint.2011.01.018","article-title":"Arginine-vasopressin V1a receptor inhibition improves neurologic outcomes following an intracerebral hemorrhagic brain injury","volume":"58","author":"Manaenko","year":"2011","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0090","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1097\/CCM.0b013e31827711c9","article-title":"Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice","volume":"41","author":"Manaenko","year":"2013","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0095","doi-asserted-by":"crossref","first-page":"675","DOI":"10.5551\/jat.3426","article-title":"A decline in platelet activation and inflammatory cell infiltration is associated with the phenotypic redifferentiation of neointimal smooth muscle cells after bare-metal stent implantation in acute coronary syndrome","volume":"17","author":"Nakagawa","year":"2010","journal-title":"J. Atheroscler. Thromb."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0100","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1038\/jcbfm.2014.99","article-title":"Plasmin-dependent modulation of the blood-brain barrier: a major consideration during TPA-induced thrombolysis?","volume":"34","author":"Niego","year":"2014","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0105","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/ana.10553","article-title":"Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases","volume":"53","author":"Power","year":"2003","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0110","doi-asserted-by":"crossref","first-page":"5723","DOI":"10.1111\/j.1742-4658.2005.04989.x","article-title":"Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family","volume":"272","author":"Reigstad","year":"2005","journal-title":"FEBS J."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0115","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jocn.2004.12.012","article-title":"Primary intracerebral hemorrhage","volume":"13","author":"Sutherland","year":"2006","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0120","doi-asserted-by":"crossref","first-page":"7427","DOI":"10.1073\/pnas.86.19.7427","article-title":"Production of platelet-derived endothelial cell growth factor by normal and transformed human cells in culture","volume":"86","author":"Usuki","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0125","doi-asserted-by":"crossref","first-page":"3198","DOI":"10.1182\/blood-2004-04-1485","article-title":"PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis","volume":"104","author":"Uutela","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.expneurol.2016.06.010_bb0130","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/sj.jcbfm.9600403","article-title":"Inflammation after intracerebral hemorrhage","volume":"27","author":"Wang","year":"2007","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.expneurol.2016.06.010_bb0135","first-page":"122","article-title":"Emerging roles of PDGF-D signaling pathway in tumor development and progression","volume":"1806","author":"Wang","year":"2010","journal-title":"Biochimica Et Biophysica Acta"},{"key":"10.1016\/j.expneurol.2016.06.010_bb0140","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/1742-2094-7-84","article-title":"Calmodulin kinase II-dependent transactivation of PDGF receptors mediates astrocytic MMP-9 expression and cell motility induced by lipoteichoic acid","volume":"7","author":"Wang","year":"2010","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.expneurol.2016.06.010_bb0145","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.pneurobio.2013.11.003","article-title":"Inflammation in intracerebral hemorrhage: from mechanisms to clinical translation","volume":"115","author":"Zhou","year":"2014","journal-title":"Prog. Neurobiol."}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488616301753?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488616301753?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T17:12:44Z","timestamp":1656695564000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488616301753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":29,"alternative-id":["S0014488616301753"],"URL":"https:\/\/doi.org\/10.1016\/j.expneurol.2016.06.010","relation":{},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of PDGF-D and PDGFR-\u03b2 in neuroinflammation in experimental ICH mice model","name":"articletitle","label":"Article Title"},{"value":"Experimental Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.expneurol.2016.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}