{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:05:56Z","timestamp":1790355956486,"version":"4.1.0"},"reference-count":76,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.expneurol.2017.12.017","type":"journal-article","created":{"date-parts":[[2018,1,4]],"date-time":"2018-01-04T18:13:55Z","timestamp":1515089635000},"page":"34-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Neuroprotective effect of acute ethanol intoxication in TBI is associated to the hierarchical modulation of early transcriptional responses"],"prefix":"10.1016","volume":"302","author":[{"given":"Akila","family":"Chandrasekar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahar","family":"Aksan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian olde","family":"Heuvel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"F\u00f6rstner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Sinske","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rida","family":"Rehman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Palmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Ludolph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Huber-Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"B\u00f6ckers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Mauceri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Kn\u00f6ll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Roselli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"14","key":"10.1016\/j.expneurol.2017.12.017_bb0005","doi-asserted-by":"crossref","first-page":"9970","DOI":"10.1074\/jbc.M113.502914","article-title":"The nuclear calcium signaling target, activating transcription factor 3 (ATF3), protects against dendrotoxicity and facilitates the recovery of synaptic transmission after an excitotoxic insult","volume":"289","author":"Ahlgren","year":"2014","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0010","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.neulet.2009.04.064","article-title":"Deficits in ERK and CREB activation in the hippocampus after traumatic brain injury","volume":"459","author":"Atkins","year":"2009","journal-title":"Neurosci. Lett."},{"issue":"10","key":"10.1016\/j.expneurol.2017.12.017_bb0015","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1177\/000313481107701033","article-title":"Correlating the blood alcohol concentration with outcome after traumatic brain injury: too much is not a bad thing","volume":"77","author":"Berry","year":"2011","journal-title":"Am. Surg."},{"issue":"14","key":"10.1016\/j.expneurol.2017.12.017_bb0020","doi-asserted-by":"crossref","first-page":"5117","DOI":"10.1073\/pnas.0305741101","article-title":"Dynamic changes in N-methyl-d-aspartate receptors after closed head injury in mice: implications for treatment of neurological and cognitive deficits","volume":"101","author":"Biegon","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0025","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fnint.2014.00010","article-title":"Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input","volume":"8","author":"Botta","year":"2014","journal-title":"Front. Integr. Neurosci."},{"issue":"9","key":"10.1016\/j.expneurol.2017.12.017_bb0030","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.jocn.2015.02.030","article-title":"Ethanol and isolated traumatic brain injury","volume":"22","author":"Brennan","year":"2015","journal-title":"J. Clin. Neurosci."},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0035","doi-asserted-by":"crossref","first-page":"564","DOI":"10.3171\/2009.12.JNS09689","article-title":"Role of extracellular glutamate measured by cerebral microdialysis in severe traumatic brain injury","volume":"113","author":"Chamoun","year":"2010","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0040","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.intimp.2017.08.002","article-title":"Acute ethanol administration results in a protective cytokine and neuroinflammatory profile in traumatic brain injury","volume":"51","author":"Chandrasekar","year":"2017","journal-title":"Int. Immunopharmacol."},{"issue":"6","key":"10.1016\/j.expneurol.2017.12.017_bb0045","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1111\/acer.13065","article-title":"Alcohol intake and reduced mortality in patients with traumatic brain injury","volume":"40","author":"Cho","year":"2016","journal-title":"Alcohol. Clin. Exp. Res."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0050","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.celrep.2017.06.040","article-title":"\u0394FosB regulates gene expression and cognitive dysfunction in a mouse model of Alzheimer's disease","volume":"20","author":"Corbett","year":"2017","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.expneurol.2017.12.017_bb0055","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1124\/jpet.102.041590","article-title":"Comparison of effect of ethanol on N-methyl-D-aspartate- and GABA-gated currents from acutely dissociated neurons: absence of regional differences in sensitivity to ethanol","volume":"304","author":"Criswell","year":"2003","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1\u20132","key":"10.1016\/j.expneurol.2017.12.017_bb0060","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.brainres.2004.04.050","article-title":"Macrokinetic analysis of blockade of NMDA-gated currents by substituted alcohols, alkanes and ethers","volume":"1015","author":"Criswell","year":"2004","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0065","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1136\/ip.2005.010975","article-title":"Changes in traffic crash mortality rates attributed to use of alcohol, or lack of a seat belt, air bag, motorcycle helmet, or bicycle helmet, United States, 1982\u20132001","volume":"12","author":"Cummings","year":"2006","journal-title":"Inj. Prev."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0070","first-page":"247","article-title":"Dynamics and regional distribution of c-fos protein expression in rat brain after a closed head injury","volume":"14","author":"Czigner","year":"2004","journal-title":"Int. J. Mol. Med."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0075","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1089\/neu.2015.4373","article-title":"Glutamate neurotransmission in rodent models of traumatic brain injury","volume":"34","author":"Dorsett","year":"2017","journal-title":"J. Neurotrauma"},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0080","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1080\/01616412.1999.11740924","article-title":"Patterns of immediate early gene mRNA expression following rodent and human traumatic brain injury","volume":"21","author":"Dutcher","year":"1999","journal-title":"Neurol. Res."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0085","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1146\/annurev.neuro.31.060407.125631","article-title":"Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system","volume":"31","author":"Flavell","year":"2008","journal-title":"Annu. Rev. Neurosci."},{"issue":"9","key":"10.1016\/j.expneurol.2017.12.017_bb0090","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1038\/nprot.2009.148","article-title":"Mouse closed head injury model induced by a weight-drop device","volume":"4","author":"Flierl","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0095","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1742-2094-8-67","article-title":"Increased cerebral (R)-[(11) C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study","volume":"8","author":"Folkersma","year":"2011","journal-title":"J. Neuroinflammation"},{"issue":"8","key":"10.1016\/j.expneurol.2017.12.017_bb0100","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.160091","article-title":"Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury","volume":"6","author":"Gey","year":"2016","journal-title":"Open Biol."},{"issue":"11","key":"10.1016\/j.expneurol.2017.12.017_bb0105","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1111\/ejn.12367","article-title":"Blocking brain-derived neurotrophic factor inhibits injury-induced hyperexcitability of hippocampal CA3 neurons","volume":"38","author":"Gill","year":"2013","journal-title":"Eur. J. Neurosci."},{"issue":"4","key":"10.1016\/j.expneurol.2017.12.017_bb0110","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1089\/08977150252932352","article-title":"Genes preferentially induced by depolarization after concussive brain injury: effects of age and injury severity","volume":"19","author":"Giza","year":"2002","journal-title":"J. Neurotrauma"},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0115","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/j.jss.2013.04.058","article-title":"Preinjury alcohol exposure attenuates the neuroinflammatory response to traumatic brain injury","volume":"184","author":"Goodman","year":"2013","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0120","first-page":"1","article-title":"Neuronal activity, TGF\u03b2-signaling and unpredictable chronic stress modulate transcription of Gadd45 family members and DNA methylation in the hippocampus","volume":"21","author":"Grassi","year":"2017","journal-title":"Cereb. Cortex"},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0125","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/nn1398","article-title":"Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity","volume":"8","author":"Hanchar","year":"2005","journal-title":"Nat. Neurosci."},{"issue":"10","key":"10.1016\/j.expneurol.2017.12.017_bb0130","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nrn2911","article-title":"Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders","volume":"11","author":"Hardingham","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"issue":"5","key":"10.1016\/j.expneurol.2017.12.017_bb5005","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1152\/jn.00350.2012","article-title":"Ethanol affects NMDA receptor signaling at climbing fiber-Purkinje cell synapses in mice and impairs cerebellar LTD","volume":"109","author":"He","year":"2013","journal-title":"J. Neurophysiol."},{"issue":"19","key":"10.1016\/j.expneurol.2017.12.017_bb0135","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1089\/neu.2015.4226","article-title":"Excitotoxicity and metabolic crisis are associated with spreading depolarizations in severe traumatic brain injury patients","volume":"33","author":"Hinzman","year":"2016","journal-title":"J. Neurotrauma"},{"issue":"1","key":"10.1016\/j.expneurol.2017.12.017_bb0140","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1046\/j.1460-9568.1999.00401.x","article-title":"Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures","volume":"11","author":"Honkaniemi","year":"1999","journal-title":"Eur. J. Neurosci."},{"issue":"8","key":"10.1016\/j.expneurol.2017.12.017_bb0145","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1097\/01.WCB.0000125888.56462.A1","article-title":"Changes in trkB-ERK1\/2-CREB\/Elk-1 pathways in hippocampal mossy fiber organization after traumatic brain injury","volume":"24","author":"Hu","year":"2004","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"23","key":"10.1016\/j.expneurol.2017.12.017_bb0155","doi-asserted-by":"crossref","first-page":"12885","DOI":"10.1073\/pnas.220412197","article-title":"Neuronal death enhanced by N-methyl-d-aspartate antagonists","volume":"97","author":"Ikonomidou","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0160","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1089\/neu.1998.15.105","article-title":"Acute ethanol administration reduces the cognitive deficits associated with traumatic brain injury in rats","volume":"15","author":"Janis","year":"1998","journal-title":"J. Neurotrauma"},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0165","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/TA.0000000000000504","article-title":"Adverse effects of admission blood alcohol on long-term cognitive function in patients with traumatic brain injury","volume":"78","author":"Joseph","year":"2015","journal-title":"J. Trauma Acute Care Surg."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0170","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.bbi.2016.11.009","article-title":"Binge ethanol in adulthood exacerbates negative outcomes following juvenile traumatic brain injury","volume":"60","author":"Karelina","year":"2017","journal-title":"Brain Behav. Immun."},{"issue":"11","key":"10.1016\/j.expneurol.2017.12.017_bb0175","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1089\/neu.2008.0552","article-title":"Prior ethanol injection promotes brain edema after traumatic brain injury","volume":"26","author":"Katada","year":"2009","journal-title":"J. Neurotrauma"},{"issue":"5","key":"10.1016\/j.expneurol.2017.12.017_bb0185","doi-asserted-by":"crossref","first-page":"876","DOI":"10.3171\/jns.1997.86.5.0876","article-title":"Paradoxical effects of acute ethanolism in experimental brain injury","volume":"86","author":"Kelly","year":"1997","journal-title":"J. Neurosurg."},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0190","doi-asserted-by":"crossref","first-page":"E317","DOI":"10.1073\/pnas.1614684114","article-title":"Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling","volume":"114","author":"Kidger","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0195","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bbi.2015.02.018","article-title":"Gadd45b is an epigenetic regulator of juvenile social behavior and alters local pro-inflammatory cytokine production in the rodent amygdala","volume":"46","author":"Kigar","year":"2015","journal-title":"Brain Behav. Immun."},{"issue":"4","key":"10.1016\/j.expneurol.2017.12.017_bb0200","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00213-009-1562-z","article-title":"The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress","volume":"205","author":"Kumar","year":"2009","journal-title":"Psychopharmacology"},{"issue":"1","key":"10.1016\/j.expneurol.2017.12.017_bb0210","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.mcn.2007.02.004","article-title":"Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory","volume":"35","author":"Li","year":"2007","journal-title":"Mol. Cell. Neurosci."},{"issue":"1","key":"10.1016\/j.expneurol.2017.12.017_bb0215","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s13041-017-0310-2","article-title":"SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model","volume":"10","author":"L\u00f6sing","year":"2017","journal-title":"Mol. Brain"},{"key":"10.1016\/j.expneurol.2017.12.017_bb0220","article-title":"Assessment of motor balance and coordination in mice using the balance beam","volume":"49","author":"Luong","year":"2011","journal-title":"J. Vis. Exp."},{"issue":"1","key":"10.1016\/j.expneurol.2017.12.017_bb0225","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10571-016-0351-6","article-title":"Impacts of blast-induced traumatic brain injury on expressions of hepatic cytochrome P450 1A2, 2B1, 2D1, and 3A2 in rats","volume":"37","author":"Ma","year":"2017","journal-title":"Cell. Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.expneurol.2017.12.017_bb0230","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.neuron.2011.04.022","article-title":"Nuclear calcium-VEGFD signaling controls maintenance of dendrite arborization necessary for memory formation","volume":"71","author":"Mauceri","year":"2011","journal-title":"Neuron"},{"issue":"5","key":"10.1016\/j.expneurol.2017.12.017_bb0235","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1128\/MCB.00360-13","article-title":"DREAM controls the on\/off switch of specific activity-dependent transcription pathways","volume":"34","author":"Mellstr\u00f6m","year":"2014","journal-title":"Mol. Cell. Biol."},{"issue":"1\u20132","key":"10.1016\/j.expneurol.2017.12.017_bb0240","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0169-328X(00)00112-1","article-title":"Chronic DeltaFosB expression and increased AP-1 transcription factor binding are associated with the long term plasticity changes in epilepsy","volume":"79","author":"Morris","year":"2000","journal-title":"Brain Res. Mol. Brain Res."},{"issue":"10","key":"10.1016\/j.expneurol.2017.12.017_bb0245","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1089\/089771503770195777","article-title":"Gene expression profile changes are commonly modulated across models and species after traumatic brain injury","volume":"20","author":"Natale","year":"2003","journal-title":"J. Neurotrauma"},{"issue":"8","key":"10.1016\/j.expneurol.2017.12.017_bb0250","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1002\/glia.22680","article-title":"Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia","volume":"62","author":"Nomaru","year":"2014","journal-title":"Glia"},{"issue":"7","key":"10.1016\/j.expneurol.2017.12.017_bb0255","first-page":"2442","article-title":"The role of c-fos in cell death and regeneration of retinal ganglion cells","volume":"43","author":"Oshitari","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0260","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.jss.2014.04.039","article-title":"Effect of alcohol in traumatic brain injury: is it really protective?","volume":"190","author":"Pandit","year":"2014","journal-title":"J. Surg. Res."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0265","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1089\/neu.2014.3488","article-title":"Acute alcohol intoxication and long-term outcome in patients with traumatic brain injury","volume":"32","author":"Raj","year":"2015","journal-title":"J. Neurotrauma"},{"issue":"6","key":"10.1016\/j.expneurol.2017.12.017_bb0270","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.3171\/2015.4.JNS141746","article-title":"Alcohol and mortality after moderate to severe traumatic brain injury: a meta-analysis of observational studies","volume":"124","author":"Raj","year":"2016","journal-title":"J. Neurosurg."},{"issue":"6","key":"10.1016\/j.expneurol.2017.12.017_bb0275","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/nn1462","article-title":"Mediates activity-induced gene expression and synaptic plasticity but not neuronal viability","volume":"8","author":"Ramanan","year":"2005","journal-title":"Nat. Neurosci."},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0280","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s12035-014-9058-1","article-title":"c-Fos protects neurons through a noncanonical mechanism involving HDAC3 interaction: identification of a 21-amino acid fragment with neuroprotective activity","volume":"53","author":"Rawat","year":"2016","journal-title":"Mol. Neurobiol."},{"issue":"4","key":"10.1016\/j.expneurol.2017.12.017_bb0285","doi-asserted-by":"crossref","first-page":"448","DOI":"10.3109\/00365521.2013.772228","article-title":"Effects of acute ethanol gavage on intestinal integrity after hemorrhage\/resuscitation","volume":"48","author":"Relja","year":"2013","journal-title":"Scand. J. Gastroenterol."},{"issue":"28","key":"10.1016\/j.expneurol.2017.12.017_bb0290","doi-asserted-by":"crossref","first-page":"11771","DOI":"10.1073\/pnas.0900484106","article-title":"Impaired long-term stability of CA1 place cell representation in mice lacking the transcription factor zif268\/egr1","volume":"106","author":"Renaudineau","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.expneurol.2017.12.017_bb0295","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/TA.0b013e3181b5dcf2","article-title":"Serum ethanol levels: predictor of survival after severe traumatic brain injury","volume":"67","author":"Salim","year":"2009","journal-title":"J. Trauma"},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0300","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s12031-015-0626-2","article-title":"Acute response of the hippocampal transcriptome following mild traumatic brain injury after controlled cortical impact in the rat","volume":"57","author":"Samal","year":"2015","journal-title":"J. Mol. Neurosci."},{"issue":"1","key":"10.1016\/j.expneurol.2017.12.017_bb0305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0082891","article-title":"Real-time optical diagnosis of the rat brain exposed to a laser-induced shock wave: observation of spreading depolarization, vasoconstriction and hypoxemia-oligemia","volume":"9","author":"Sato","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.expneurol.2017.12.017_bb0310","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1093\/alcalc\/agh159","article-title":"Alcohol intake and the pattern of trauma in young adults and working aged people admitted after trauma","volume":"40","author":"Savola","year":"2005","journal-title":"Alcohol Alcohol."},{"issue":"11","key":"10.1016\/j.expneurol.2017.12.017_bb5000","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s00011-012-0515-x","article-title":"GADD45\u03b3 regulates TNF-\u03b1 and IL-6 synthesis in THP-1 cells","volume":"61","author":"Shin","year":"2012","journal-title":"Inflamm. Res."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0315","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.bbi.2014.11.006","article-title":"Alcohol exposure after mild focal traumatic brain injury impairs neurological recovery and exacerbates localized neuroinflammation","volume":"45","author":"Teng","year":"2015","journal-title":"Brain Behav. Immun."},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0320","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0120356","article-title":"Binge ethanol prior to traumatic brain injury worsens sensorimotor functional recovery in rats","volume":"10","author":"Vaagenes","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.expneurol.2017.12.017_bb0325","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1111\/acer.13446","article-title":"Acute alcohol binge deteriorates metabolic and respiratory compensation capability after blunt chest trauma followed by hemorrhagic shock-a new research model","volume":"41","author":"Wagner","year":"2017","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0330","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.neuroscience.2012.06.010","article-title":"Increased inflammation and brain injury after transient focal cerebral ischemia in activating transcription factor 3 knockout mice","volume":"220","author":"Wang","year":"2012","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/j.expneurol.2017.12.017_bb0335","doi-asserted-by":"crossref","first-page":"390","DOI":"10.3171\/2012.8.JNS12736","article-title":"Reduction of brain edema and expression of aquaporins with acute ethanol treatment after traumatic brain injury","volume":"118","author":"Wang","year":"2013","journal-title":"J. Neurosurg."},{"issue":"12","key":"10.1016\/j.expneurol.2017.12.017_bb0340","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1097\/WNR.0000000000000219","article-title":"Hippocampal immediate early gene transcription in the rat fluid percussion traumatic brain injury model","volume":"25","author":"Wang","year":"2014","journal-title":"Neuroreport"},{"key":"10.1016\/j.expneurol.2017.12.017_bb0345","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3389\/fphar.2012.00060","article-title":"Altered calcium signaling following traumatic brain injury","volume":"3","author":"Weber","year":"2012","journal-title":"Front. Pharmacol."},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0350","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1074\/jbc.M009209200","article-title":"Traumatic injury of cortical neuronscauses changes in intracellular calcium stores and capacitative calcium influx","volume":"276","author":"Weber","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.expneurol.2017.12.017_bb0355","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1089\/neu.1990.7.141","article-title":"Traumatic brain injury creates biphasic systemic hemodynamic and organ blood flow responses in rats","volume":"7","author":"Yuan","year":"1990","journal-title":"J. Neurotrauma"},{"issue":"5","key":"10.1016\/j.expneurol.2017.12.017_bb0360","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/npp.2012.260","article-title":"fosB-null mice display impaired adult hippocampal neurogenesis and spontaneous epilepsy with depressive behavior","volume":"38","author":"Yutsudo","year":"2013","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"10.1016\/j.expneurol.2017.12.017_bb0365","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/ng859","article-title":"C-fos regulates neuronal excitability and survival","volume":"30","author":"Zhang","year":"2002","journal-title":"Nat. Genet."},{"issue":"8","key":"10.1016\/j.expneurol.2017.12.017_bb0370","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000604","article-title":"Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity","volume":"5","author":"Zhang","year":"2009","journal-title":"PLoS Genet."},{"issue":"13","key":"10.1016\/j.expneurol.2017.12.017_bb0375","doi-asserted-by":"crossref","first-page":"4978","DOI":"10.1523\/JNEUROSCI.2672-10.2011","article-title":"A signaling cascade of nuclear calcium-CREB-ATF3 activated by synaptic NMDA receptors defines a gene repression module that protects against extrasynaptic NMDA receptor-induced neuronal cell death and ischemic brain damage","volume":"31","author":"Zhang","year":"2011","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.expneurol.2017.12.017_bb0380","doi-asserted-by":"crossref","first-page":"9220","DOI":"10.4238\/2014.November.7.9","article-title":"Analysis of key genes and modules during the courses of traumatic brain injury with microarray technology","volume":"13","author":"Zhang","year":"2014","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.expneurol.2017.12.017_bb0385","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3389\/fnbeh.2014.00125","article-title":"Robust and reliable non-invasive test for stress responsivity in mice","volume":"8","author":"Zimprich","year":"2014","journal-title":"Front. Behav. Neurosci."}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488617303527?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488617303527?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,25]],"date-time":"2020-10-25T06:49:35Z","timestamp":1603608575000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488617303527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":76,"alternative-id":["S0014488617303527"],"URL":"https:\/\/doi.org\/10.1016\/j.expneurol.2017.12.017","relation":{},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroprotective effect of acute ethanol intoxication in TBI is associated to the hierarchical modulation of early transcriptional responses","name":"articletitle","label":"Article Title"},{"value":"Experimental Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.expneurol.2017.12.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}