{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T03:49:49Z","timestamp":1787629789925,"version":"build-2736575974"},"reference-count":44,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Parasitology"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.exppara.2008.11.006","type":"journal-article","created":{"date-parts":[[2008,11,28]],"date-time":"2008-11-28T09:25:08Z","timestamp":1227864308000},"page":"238-241","source":"Crossref","is-referenced-by-count":51,"title":["Toxoplasma gondii: Reproductive parameters in experimentally infected male rats"],"prefix":"10.1016","volume":"121","author":[{"given":"Konstantinos I.","family":"Terpsidis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita G.","family":"Papazahariadou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis A.","family":"Taitzoglou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos G.","family":"Papaioannou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios P.","family":"Georgiadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis Th.","family":"Theodoridis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exppara.2008.11.006_bib1","first-page":"104","article-title":"Comparative experimental transmission studies with Nigerian isolates and TS-I strain of Toxoplasma gondii in sheep","volume":"8","author":"Aganga","year":"1988","journal-title":"Journal of Animal Production Research"},{"key":"10.1016\/j.exppara.2008.11.006_bib2","first-page":"593","article-title":"Hypothalamic origin of reproductive failure in chronic experimental toxoplasmosis","volume":"30","author":"Antonios","year":"2000","journal-title":"Journal of Egyptian Society of Parasitology"},{"key":"10.1016\/j.exppara.2008.11.006_bib3","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1001\/archneur.1983.04050080096025","article-title":"Acute toxoplasmic encephalitis in a normal adult","volume":"40","author":"Bach","year":"1983","journal-title":"Archives of Neurology"},{"key":"10.1016\/j.exppara.2008.11.006_bib4","doi-asserted-by":"crossref","first-page":"3724","DOI":"10.1128\/JCM.36.12.3724-3725.1998","article-title":"Toxoplasma gondii-associated Guillain-Barre syndrome in an immunocompetent patient","volume":"36","author":"Bossi","year":"1998","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.exppara.2008.11.006_bib5","doi-asserted-by":"crossref","first-page":"4037","DOI":"10.1128\/JCM.40.11.4037-4044.2002","article-title":"Severe acquired toxoplasmosis in immunocompetent adult patients in French Guiana","volume":"40","author":"Carme","year":"2002","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.exppara.2008.11.006_bib6","first-page":"107","article-title":"Evaluation of semen parameters of boars (Sus scrofa) infected with Toxoplasma gondii","volume":"25","author":"Costa","year":"2004","journal-title":"Semina Ciencias Agrarias Londrina"},{"key":"10.1016\/j.exppara.2008.11.006_bib7","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1128\/JCM.36.1.324-324.1998","article-title":"Severe toxoplasmosis caused by a Toxoplasma gondii strain with anew isoenzyme type acquired in French Guiana","volume":"36","author":"Dard\u00e9","year":"1998","journal-title":"Journal of Clinical Microbiology"},{"key":"10.1016\/j.exppara.2008.11.006_bib8","first-page":"25","article-title":"Opportunistic infections of the testis in the acquired immunodeficiency syndrome","volume":"57","author":"De Paepe","year":"1990","journal-title":"Mount Sinai Journal of Medicine"},{"key":"10.1016\/j.exppara.2008.11.006_bib9","first-page":"661","article-title":"Epizootic toxoplasmosis associated with abortion in dairy goats in Montana","volume":"178","author":"Dubey","year":"1981","journal-title":"Journal of American Veterinary Medicine Association"},{"key":"10.1016\/j.exppara.2008.11.006_bib10","doi-asserted-by":"crossref","first-page":"951","DOI":"10.2307\/3284205","article-title":"Pathogenicity and infectivity of Toxoplasma gondii oocysts for rats","volume":"82","author":"Dubey","year":"1996","journal-title":"Journal of Parasitology"},{"key":"10.1016\/j.exppara.2008.11.006_bib11","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/j.1550-7408.1997.tb05965.x","article-title":"Bradyzoite-induced murine toxoplasmosis: stage conversion, pathogenesis and tissue cyst formation in mice fed bradyzoites of different strains of Toxoplasma gondii","volume":"44","author":"Dubey","year":"1997","journal-title":"Journal of Eukaryotic Microbiology"},{"key":"10.1016\/j.exppara.2008.11.006_bib12","doi-asserted-by":"crossref","first-page":"505","DOI":"10.2307\/3278784","article-title":"Experimental Toxoplasma infection in mice with strains producing oocysts","volume":"59","author":"Dubey","year":"1973","journal-title":"Journal of Parasitology"},{"key":"10.1016\/j.exppara.2008.11.006_bib13","series-title":"Toxoplasmosis of Animals and Man","author":"Dubey","year":"1988"},{"key":"10.1016\/j.exppara.2008.11.006_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0304-4017(97)00227-6","article-title":"Toxoplasmosis of rats. A review, with considerations of their value as an animal model and their possible role in epidemiology","volume":"77","author":"Dubey","year":"1998","journal-title":"Veterinary Parasitology"},{"key":"10.1016\/j.exppara.2008.11.006_bib15","first-page":"794","article-title":"Prolonged excretion of Toxoplasma gondii in semen of goats","volume":"41","author":"Dubey","year":"1980","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.exppara.2008.11.006_bib16","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1128\/IAI.59.9.3301-3302.1991","article-title":"Rat model of congenital toxoplasmosis","volume":"59","author":"Dubey","year":"1991","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.exppara.2008.11.006_bib17","doi-asserted-by":"crossref","first-page":"438","DOI":"10.2307\/3284082","article-title":"Infectivity of low numbers of Toxoplasma gondii oocysts to pigs","volume":"82","author":"Dubey","year":"1996","journal-title":"Journal of Parasitology"},{"key":"10.1016\/j.exppara.2008.11.006_bib18","first-page":"585","article-title":"Toxoplasma gondii encephalitis in an immunocompetent adult: a case report","volume":"71","author":"Grant","year":"1987","journal-title":"South African Medical Journal"},{"key":"10.1016\/j.exppara.2008.11.006_bib19","series-title":"Human Toxoplasmosis","first-page":"56","article-title":"Clinical features","author":"Ho-Yen","year":"1992"},{"key":"10.1016\/j.exppara.2008.11.006_bib20","first-page":"323","article-title":"Studies on the significane of sexual intercourse for the transmission of Toxoplasma gondii","volume":"231","author":"Janitschke","year":"1975","journal-title":"Zentralblatt fur Bakteriologie"},{"key":"10.1016\/j.exppara.2008.11.006_bib21","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1210\/endo-126-4-2145","article-title":"Interleukin-1 inhibits the ovarian steroid-induced luteinizing hormone surge and release of hypothalamic luteinizing hormone-releasing hormone in rats","volume":"126","author":"Kalra","year":"1990","journal-title":"Endocrinology"},{"key":"10.1016\/j.exppara.2008.11.006_bib22","first-page":"163","article-title":"Involvement of organum vasculosum of lamina terminalis and preoptic area in interleukin 1B-induced ACTH release","volume":"258","author":"Katsuura","year":"1990","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.exppara.2008.11.006_bib23","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1006\/faat.1995.1140","article-title":"Dibromoacetic acid affects reproductive competence and sperm quality in the male rats","volume":"28","author":"Linder","year":"1995","journal-title":"Fundamental and Applied Toxicology"},{"key":"10.1016\/j.exppara.2008.11.006_bib24","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1006\/faat.1995.1038","article-title":"Reproductive toxicology of aluminium in male mice","volume":"25","author":"Liobet","year":"1995","journal-title":"Fundamental and Applied Toxicology"},{"key":"10.1016\/j.exppara.2008.11.006_bib25","doi-asserted-by":"crossref","unstructured":"Lopes, W.D.Z., Costa, A.J., Souza, F.A., Rodrigues, J.D.F., Costa, G.H.N., Soares, V.E., Silva, G.S., 2008. Semen variables of sheep (Ovis aries) experimentally infected with Toxoplasma gondii. Animal Reproduction Science, in press.","DOI":"10.1016\/j.anireprosci.2008.03.015"},{"key":"10.1016\/j.exppara.2008.11.006_bib26","first-page":"592","article-title":"Infertility experiment on male mice infected with Toxoplasma (In Chinese with English abstract)","volume":"21","author":"Lu","year":"2005","journal-title":"Chinese Journal of Zoonoses"},{"key":"10.1016\/j.exppara.2008.11.006_bib27","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1056\/NEJM199309303291403","article-title":"Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome","volume":"329","author":"Luft","year":"1993","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.exppara.2008.11.006_bib28","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/0002-9343(84)90381-4","article-title":"Toxoplasmosis presenting as panhypopituitarism in a patient with the acquired immune deficiency syndrome","volume":"77","author":"Milligan","year":"1984","journal-title":"American Journal of Medicine"},{"key":"10.1016\/j.exppara.2008.11.006_bib29","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1590\/S0100-736X2007001000008","article-title":"Toxoplasma gondii in semen of experimentally infected swine","volume":"27","author":"Moura","year":"2007","journal-title":"Pesquisa Veterinaria Brasileira"},{"key":"10.1016\/j.exppara.2008.11.006_bib30","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0940-2993(11)80260-5","article-title":"Histopathology of chemically induced testicular atrophy in rats","volume":"47","author":"Nolte","year":"1995","journal-title":"Experimental and Toxicologic Pathology"},{"key":"10.1016\/j.exppara.2008.11.006_bib31","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1051\/parasite\/1999061063","article-title":"Experimental congenital toxoplasmosis in Wistar and Holtzman rats","volume":"6","author":"Paulino","year":"1999","journal-title":"Parasite"},{"key":"10.1016\/j.exppara.2008.11.006_bib32","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1530\/rep.0.1210207","article-title":"Significance of incorporating measures of sperm production and function into rat toxicology studies","volume":"121","author":"Perreault","year":"2001","journal-title":"Reproduction"},{"key":"10.1016\/j.exppara.2008.11.006_bib33","first-page":"503","article-title":"Toxoplasma infection in males with sterility in Shenyang, China (In Chinese with English abstract)","volume":"11","author":"Qi","year":"2005","journal-title":"Zhonghua Nan Ke Xue"},{"key":"10.1016\/j.exppara.2008.11.006_bib34","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1097\/00005792-199207000-00005","article-title":"Toxoplasma encephalitis in patients with the acquired immunodeficiency syndrome","volume":"71","author":"Renold","year":"1992","journal-title":"Medicine"},{"key":"10.1016\/j.exppara.2008.11.006_bib35","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1095\/biolreprod45.4.523","article-title":"Effect of stress on the activity of the hypothalamic- pituitary-gonadal axis: peripheral and central mechanisms","volume":"45","author":"Rivier","year":"1991","journal-title":"Biology of Reproduction"},{"key":"10.1016\/j.exppara.2008.11.006_bib36","unstructured":"Scarpelli, L.C., 2001. Viabilidate da transmiss\u00e3o ven\u00e9rea do Toxoplasma gondii em bovinos. Disserta\u00e7\u00e3o de Mestrado, FCAV, Universidade Estadual Paulista, Jaboticabal, SP. 128."},{"key":"10.1016\/j.exppara.2008.11.006_bib37","first-page":"9","article-title":"Intracerebral toxoplasmosis presenting as a mass lesion","volume":"4","author":"Schulhof","year":"1975","journal-title":"Surgical Neurology"},{"key":"10.1016\/j.exppara.2008.11.006_bib38","first-page":"147","article-title":"Hypothalamic neuronal responses to cytokines","volume":"63","author":"Shibata","year":"1990","journal-title":"The Yale Journal of Biology and Medicine"},{"key":"10.1016\/j.exppara.2008.11.006_bib39","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0006-8993(91)90639-D","article-title":"Human recombinant tumor necrosis factor and interferon affect the activity of neurons in the organum vasculosum laminae terminalis","volume":"562","author":"Shibata","year":"1991","journal-title":"Brain Research"},{"key":"10.1016\/j.exppara.2008.11.006_bib40","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1007\/BF00931615","article-title":"Etiology of ovarian dysfunction in chronic murine toxoplasmosis","volume":"81","author":"Stahl","year":"1995","journal-title":"Parasitology Research"},{"key":"10.1016\/j.exppara.2008.11.006_bib41","first-page":"55","article-title":"Acute Toxoplasma gondii infection affects the reproductive function of male mice","volume":"14","author":"Sun","year":"2008","journal-title":"Zhonghua Nan Ke Xue"},{"key":"10.1016\/j.exppara.2008.11.006_bib42","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000125096","article-title":"Interleukin-1 directly stimulates the release of corticotropin releasing factor from rat hypothalamus","volume":"49","author":"Tsagarakis","year":"1989","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.exppara.2008.11.006_bib43","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1136\/jcp.55.12.965","article-title":"Two case reports of pituitary adenoma associated with Toxoplasma gondii infection","volume":"55","author":"Zhang","year":"2002","journal-title":"Journal of Clinical Pathology"},{"key":"10.1016\/j.exppara.2008.11.006_bib44","first-page":"350","article-title":"Survey of infection of Toxoplasma gondii in infertile couples in Suzhou countryside (In Chinese with English abstract)","volume":"8","author":"Zhou","year":"2002","journal-title":"Zhonghua Nan Ke Xue"}],"container-title":["Experimental Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489408002944?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489408002944?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T19:10:25Z","timestamp":1589224225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014489408002944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0014489408002944"],"URL":"https:\/\/doi.org\/10.1016\/j.exppara.2008.11.006","relation":{},"ISSN":["0014-4894"],"issn-type":[{"value":"0014-4894","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}