{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:33:41Z","timestamp":1777541621462,"version":"3.51.4"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Parasitology"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.exppara.2010.01.004","type":"journal-article","created":{"date-parts":[[2010,1,21]],"date-time":"2010-01-21T09:29:41Z","timestamp":1264066181000},"page":"106-113","source":"Crossref","is-referenced-by-count":16,"title":["Molecular cloning and characterization of two genes encoding 2-Cys peroxiredoxins from Fasciola gigantica"],"prefix":"10.1016","volume":"125","author":[{"given":"Kulathida","family":"Chaithirayanon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasert","family":"Sobhon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exppara.2010.01.004_bib1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0166-6851(02)00031-2","article-title":"The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase","volume":"121","author":"Alger","year":"2002","journal-title":"Molecular and Biochemical Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib2","first-page":"34279","article-title":"Cloning and characterization of three differentially expressed peroxidoxin genes from Leishmania chagasi","volume":"276","author":"Barr","year":"2001","journal-title":"Evidence for an enzymatic detoxification of hydroxyl radicals. Journal of Biological Chemistry"},{"key":"10.1016\/j.exppara.2010.01.004_bib3","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/protein\/gzh037","article-title":"Feature-based prediction of non-classical and leaderless protein secretion","volume":"17","author":"Bendtsen","year":"2004","journal-title":"Protein Engineering Design and Selection"},{"key":"10.1016\/j.exppara.2010.01.004_bib4","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jmb.2004.05.028","article-title":"Improved prediction of signal peptides: SignalP 3.0","volume":"340","author":"Bendtsen","year":"2004","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/j.exppara.2010.01.004_bib5","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0169-4758(88)90162-7","article-title":"Helminth anti-oxidant enzymes: a protective mechanism against host oxidants?","volume":"4","author":"Callahan","year":"1988","journal-title":"Parasitology Today"},{"key":"10.1016\/j.exppara.2010.01.004_bib6","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1017\/S0031182006001119","article-title":"Molecular and immunological characterization of encoding gene and 14-3-3 protein 1 in Fasciola gigantica","volume":"133","author":"Chaithirayanon","year":"2006","journal-title":"Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib7","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1128\/IAI.73.1.166-173.2005","article-title":"Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages","volume":"73","author":"Donnelly","year":"2005","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.exppara.2010.01.004_bib8","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1515\/BC.2002.040","article-title":"Peroxiredoxins","volume":"383","author":"Hofmann","year":"2002","journal-title":"Biological Chemistry"},{"key":"10.1016\/j.exppara.2010.01.004_bib9","doi-asserted-by":"crossref","first-page":"13963","DOI":"10.1016\/S0021-9258(18)71625-6","article-title":"Thioredoxin and glutaredoxin systems","volume":"264","author":"Holmgren","year":"1989","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.exppara.2010.01.004_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.jmb.2004.03.021","article-title":"A peroxiredoxin specifically expressed in two types of pharyngeal neurons is required for normal growth and egg production in Caenorhabditis elegans","volume":"338","author":"Isermann","year":"2004","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/j.exppara.2010.01.004_bib11","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1172\/JCI111830","article-title":"Role of granulocyte oxygen products in damage of Schistosoma mansoni eggs in vitro","volume":"75","author":"Kazura","year":"1985","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.exppara.2010.01.004_bib12","doi-asserted-by":"crossref","first-page":"3941","DOI":"10.1128\/IAI.68.7.3941-3948.2000","article-title":"Molecular cloning and expression of Cu\/Zn-containing superoxide dismutase from Fasciola hepatica","volume":"68","author":"Kim","year":"2000","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.exppara.2010.01.004_bib13","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.molbiopara.2006.05.004","article-title":"2-Cys peroxiredoxins from Schistosoma japonicum: the expression profile and localization in the life cycle","volume":"149","author":"Kumagai","year":"2006","journal-title":"Molecular and Biochemical Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib14","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1017\/S0031182097001170","article-title":"Cloning of peroxiredoxin, a novel antioxidant enzyme, from the helminth parasite Fasciola hepatica","volume":"115","author":"McGonigle","year":"1997","journal-title":"Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib15","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0169-4758(97)01211-8","article-title":"Peroxidoxins: a new antioxidant family","volume":"14","author":"McGonigle","year":"1998","journal-title":"Parasitology Today"},{"key":"10.1016\/j.exppara.2010.01.004_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molbiopara.2004.02.010","article-title":"Molecular cloning and analysis of stage and tissue specific expression of Cathepsin B encoding genes from Fasciola gigantica","volume":"136","author":"Meemon","year":"2004","journal-title":"Molecular and Biochemical Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib17","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/0020-7519(88)90101-4","article-title":"Antioxidant systems in Schistosoma mansoni: correlation between susceptibility to oxidant killing and the levels of scavengers of hydrogen peroxide and oxygen free radicals","volume":"18","author":"Mkoji","year":"1998","journal-title":"International Journal for Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib18","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1074\/mcp.M600375-MCP200","article-title":"Comparative proteomics of excretory\u2013secretory proteins released by the liver fluke Fasciola hepatica in sheep host bile and during in vitro culture ex host","volume":"6","author":"Morphew","year":"2007","journal-title":"Molecular and Cellular Proteomics"},{"key":"10.1016\/j.exppara.2010.01.004_bib19","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1006\/abbi.1996.0386","article-title":"The iron-catalyzed oxidation of dithiothreitol is a biphasic process: hydrogen peroxide is involved in the initiation of a free radical chain of reactions","volume":"333","author":"Netto","year":"1996","journal-title":"Archives of Biochemistry and Biophysics."},{"key":"10.1016\/j.exppara.2010.01.004_bib20","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1751-0813.1995.tb03546.x","article-title":"Resistance of Fasciola hepatica to triclabendazole","volume":"72","author":"Overend","year":"1995","journal-title":"Australian Veterinary Journal"},{"key":"10.1016\/j.exppara.2010.01.004_bib21","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1017\/S0031182098003394","article-title":"CuZn superoxide dismutase activities from Fasciola hepatica","volume":"117","author":"Piacenza","year":"1998","journal-title":"Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1006\/expr.2000.4495","article-title":"Fasciola hepatica: heterologous expression and functional characterization of a thioredoxin peroxidase","volume":"95","author":"Salazar-Calder\u00f3n","year":"2000","journal-title":"Experimental Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib23","unstructured":"Sambrook, J., Fritsch, E.F., Maniatis, T., 2001. Molecular cloning: a laboratory manual, third ed. Cold Spring Harbor: Cold Spring Harbor laboratory Press."},{"key":"10.1016\/j.exppara.2010.01.004_bib24","doi-asserted-by":"crossref","first-page":"5016","DOI":"10.1016\/j.febslet.2006.08.019","article-title":"Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica","volume":"580","author":"Sekiya","year":"2006","journal-title":"FEBS Letters"},{"key":"10.1016\/j.exppara.2010.01.004_bib25","series-title":"Fasciolosis","first-page":"465","article-title":"Fasciola gigantica: epidemiology, control, immunology and molecular biology","author":"Spithill","year":"1999"},{"key":"10.1016\/j.exppara.2010.01.004_bib26","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.molbiopara.2008.04.010","article-title":"Characterization of the antioxidant enzyme, thioredoxin peroxidase, from the carcinogenic human liver fluke, Opisthorchis viverrini","volume":"160","author":"Suttiprapa","year":"2008","journal-title":"Molecular and Biochemical Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib27","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0014-4894(92)90142-W","article-title":"Primary sequence heterogeneity and tissue expression of glutathione S-transferases of Fasciola hepatica","volume":"74","author":"Wijffels","year":"1992","journal-title":"Experimental Parasitology"},{"key":"10.1016\/j.exppara.2010.01.004_bib28","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1128\/IAI.69.2.1134-1141.2001","article-title":"Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase","volume":"69","author":"Williams","year":"2001","journal-title":"Infection and Immunity"},{"key":"10.1016\/j.exppara.2010.01.004_bib29","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0968-0004(02)00003-8","article-title":"Structure, mechanism and regulation of peroxiredoxins","volume":"28","author":"Wood","year":"2003","journal-title":"Trends in Biochemical Science"}],"container-title":["Experimental Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448941000007X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448941000007X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T15:53:23Z","timestamp":1634745203000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001448941000007X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S001448941000007X"],"URL":"https:\/\/doi.org\/10.1016\/j.exppara.2010.01.004","relation":{},"ISSN":["0014-4894"],"issn-type":[{"value":"0014-4894","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}