{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T12:39:21Z","timestamp":1785328761517,"version":"3.55.0"},"reference-count":91,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Parasitology"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.exppara.2014.05.004","type":"journal-article","created":{"date-parts":[[2014,5,17]],"date-time":"2014-05-17T21:31:05Z","timestamp":1400362265000},"page":"60-68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":65,"special_numbering":"C","title":["Antileishmanial activity and cytotoxicity of Brazilian plants"],"prefix":"10.1016","volume":"143","author":[{"given":"Tatiana G.","family":"Ribeiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Ch\u00e1vez-Fumagalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diogo G.","family":"Valadares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju\u00e7ara R.","family":"Franca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula S.","family":"Lage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana C.","family":"Duarte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro H.R.","family":"Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivian T.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourena E.","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L.A.","family":"Arruda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 A.G.","family":"Faraco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo A.F.","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel O.","family":"Castilho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exppara.2014.05.004_b0005","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jep.2010.06.011","article-title":"Investigation of plant extracts in traditional medicine of the Brazilian Cerrado against protozoans and yeasts","volume":"131","author":"Albernaz","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0010","doi-asserted-by":"crossref","first-page":"e35671","DOI":"10.1371\/journal.pone.0035671","article-title":"Leishmaniasis worldwide and global estimates of its incidence","volume":"7","author":"Alvar","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.exppara.2014.05.004_b0015","first-page":"667","article-title":"Chrysobalanus icaco L. extract for antiangiogenic potential observation","volume":"5","author":"Alves de Paulo","year":"2000","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.exppara.2014.05.004_b0020","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.jep.2010.01.008","article-title":"Hypoglycemic effects of Cecropia pachystachya in normal and alloxan-induced diabetic rats","volume":"128","author":"Arag\u00e3o","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0025","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1089\/jmf.2010.0251","article-title":"Jacaranda cuspidifolia Mart. (Bignoniaceae) as an antibacterial agent","volume":"14","author":"Arruda","year":"2011","journal-title":"J. Med. Food"},{"key":"10.1016\/j.exppara.2014.05.004_b0030","first-page":"1","article-title":"An\u00e1lise fitoqu\u00edmica e atividade antimicobacteriana de extratos de Jacaranda cuspidifolia Mart. (Bignoniaceae)","volume":"14","author":"Arruda","year":"2012","journal-title":"Rev. Bras. Plantas Medicinais"},{"key":"10.1016\/j.exppara.2014.05.004_b0035","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.micres.2012.02.005","article-title":"In vitro antibacterial potential of Eugenia jambolana seed extracts against multidrug-resistant human bacterial pathogens","volume":"167","author":"Bag","year":"2012","journal-title":"Microbiol. Res."},{"key":"10.1016\/j.exppara.2014.05.004_b0040","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.bbrc.2004.03.097","article-title":"Leishmania donovani induces interferon regulatory factor in murine macrophages: a host defense response","volume":"317","author":"Balaraman","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.exppara.2014.05.004_b0045","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.foodres.2011.02.007","article-title":"Phytochemistry, traditional uses and pharmacology of Eugenia jambolana Lam. (black plum): a review","volume":"44","author":"Baliga","year":"2011","journal-title":"Food Res. Int."},{"key":"10.1016\/j.exppara.2014.05.004_b0050","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1590\/S0001-37652010000300008","article-title":"Anti-inflammatory effect of the ethanolic extract from Bowdichia virgilioides H.B.K stem bark","volume":"82","author":"Barros","year":"2010","journal-title":"An. Acad. Bras. Ci\u00eanc."},{"key":"10.1016\/j.exppara.2014.05.004_b0055","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0367-326X(00)00185-4","article-title":"Antibacterial and allelopathic activity of extract from Castanea sativa leaves","volume":"71","author":"Basile","year":"2000","journal-title":"Fitoterapia"},{"key":"10.1016\/j.exppara.2014.05.004_b0060","first-page":"239","article-title":"Antibacterial principles of the seeds of Eugenia jambolana","volume":"25","author":"Bhuiyan","year":"1996","journal-title":"Bangladesh J. Bot."},{"key":"10.1016\/j.exppara.2014.05.004_b0065","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1039\/c0fo00008f","article-title":"Comparison of the polyphenolic composition and antioxidant activity of European commercial fruit juices","volume":"1","author":"Borges","year":"2010","journal-title":"Food Funct."},{"key":"10.1016\/j.exppara.2014.05.004_b0070","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jep.2008.08.004","article-title":"Brazilian medicinal plants described by 19th century European naturalists and in the official pharmacopoeia","volume":"120","author":"Brand\u00e3o","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0075","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.jep.2012.06.052","article-title":"Useful Brazilian plants listed in the field books of the French naturalist Auguste de Saint-Hilaire (1779\u20131853)","volume":"143","author":"Brand\u00e3o","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0080","unstructured":"Brazilian Pharmacopeia, 2010. Bras\u00edlia: ANVISA, 2010. Available at: <http:\/\/www.anvisa.gov.br\/hotsite\/cd_farmacopeia\/index.htm> (accessed March, 2014)."},{"key":"10.1016\/j.exppara.2014.05.004_b0085","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.2174\/138955708786140990","article-title":"Antimicrobial and antiviral activity of hydrolysable tannins","volume":"8","author":"Buzzini","year":"2008","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.exppara.2014.05.004_b0090","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1007\/s10600-011-9953-x","article-title":"Phytochemical study and antimicrobial activity of Chrysobalanus icaco","volume":"47","author":"Castilho","year":"2011","journal-title":"Chem. Nat. Compd."},{"key":"10.1016\/j.exppara.2014.05.004_b0095","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.jep.2012.03.031","article-title":"Screening of Brazilian medicinal plants for antiviral activity against rotavirus","volume":"141","author":"Cec\u00edlio","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0100","first-page":"356","article-title":"Antibacterial activity of Syzygium species","volume":"69","author":"Chattopadhyay","year":"1998","journal-title":"Fitoterapia"},{"key":"10.1016\/j.exppara.2014.05.004_b0105","doi-asserted-by":"crossref","first-page":"3988","DOI":"10.1128\/IAI.71.7.3988-3994.2003","article-title":"Immune responses induced by the Leishmania (Leishmania) donovani A2 antigen, but not by the LACK antigen, are protective against experimental Leishmania (Leishmania) amazonensis infection","volume":"71","author":"Coelho","year":"2003","journal-title":"Infect. Immun."},{"key":"10.1016\/j.exppara.2014.05.004_b0110","unstructured":"Committee WHOE, 2010. Control of the Leishmaniases. World Health Organization Technical Report Series xii\u2013xiii, 1\u2013186, Back Cover."},{"key":"10.1016\/j.exppara.2014.05.004_b0115","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0378-8741(98)00194-9","article-title":"Pharmacological basis for the empirical use of Eugenia uniflora l. (Myrtaceae) as antihypertensive","volume":"66","author":"Consolini","year":"1999","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0120","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jep.2005.12.006","article-title":"Cardiotonic and sedative effects of Cecropia pachystachya Mart. (ambay) on isolated rat hearts and conscious mice","volume":"106","author":"Consolini","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0125","series-title":"Dicion\u00e1rio das plantas \u00fateis do Brasil e das ex\u00f3ticas cultivadas","author":"Corr\u00eaa","year":"1926"},{"key":"10.1016\/j.exppara.2014.05.004_b0130","series-title":"Dicion\u00e1rio das plantas \u00fateis do Brasil e das ex\u00f3ticas cultivadas","author":"Corr\u00eaa","year":"1952"},{"key":"10.1016\/j.exppara.2014.05.004_b0135","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/CMR.12.4.564","article-title":"Plant products as antimicrobial agents","volume":"12","author":"Cowan","year":"1999","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.exppara.2014.05.004_b0140","series-title":"Da flora medicinal do Rio Grande do Sul","author":"D\u2019\u00c1vila","year":"1910"},{"key":"10.1016\/j.exppara.2014.05.004_b0145","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.cimid.2004.03.004","article-title":"Leishmaniasis: current situation and new perspectives","volume":"27","author":"Desjeux","year":"2004","journal-title":"Comp. Immunol., Microbiol. Infect. Dis."},{"key":"10.1016\/j.exppara.2014.05.004_b0150","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0367-326X(01)00362-8","article-title":"Medicinal plants popularly used in the Brazilian tropical Atlantic forest","volume":"73","author":"Di Stasi","year":"2002","journal-title":"Fitoterapia"},{"key":"10.1016\/j.exppara.2014.05.004_b0155","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jep.2006.07.003","article-title":"Plants popularly used for losing weight purposes in Porto Alegre, South Brazil","volume":"109","author":"Dickel","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0160","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.phymed.2009.08.002","article-title":"Antiprotozoal activity of betulinic acid derivatives","volume":"17","author":"Dom\u00ednguez-Carmona","year":"2010","journal-title":"Phytomedicine"},{"key":"10.1016\/j.exppara.2014.05.004_b0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1472-6882-12-9","article-title":"In vitro and in vivo safety evaluation of Dipteryx alata vogel extract","volume":"12","author":"Esteves-Pedro","year":"2012","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.exppara.2014.05.004_b0170","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jep.2007.08.007","article-title":"Evaluation of the leishmanicidal activity of plants used by Peruvian Chayahuita ethnic group","volume":"114","author":"Estevez","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0175","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0304-3835(02)00593-1","article-title":"Pentacyclic triterpenes from Chrysobalanaceae species: cytotoxicity on multidrug resistant and sensitive leukemia cell lines","volume":"190","author":"Fernandes","year":"2003","journal-title":"Cancer Lett."},{"key":"10.1016\/j.exppara.2014.05.004_b0180","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.fct.2013.03.012","article-title":"Phenolic compounds from Jacaranda caroba (Vell.) A. DC.: approaches to neurodegenerative disorders","volume":"57","author":"Ferreres","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.exppara.2014.05.004_b0185","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.3390\/molecules14072317","article-title":"Pentavalent antimonials: new perspectives for oral drugs","volume":"14","author":"Fr\u00e9zard","year":"2009","journal-title":"Molecules"},{"key":"10.1016\/j.exppara.2014.05.004_b0190","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jep.2008.10.015","article-title":"Jacaranda \u2013 an ethnopharmacological and phytochemical review","volume":"121","author":"Gachet","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0195","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s00436-012-3167-4","article-title":"Antimycobacterial and antileishmanial effects of microfungi isolated from tropical regions in M\u00e9xico","volume":"112","author":"Gamboa-Angulo","year":"2012","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2014.05.004_b0200","doi-asserted-by":"crossref","DOI":"10.5402\/2012\/104540","article-title":"Activity of Cuban plants extracts against Leishmania amazonensis","author":"Garc\u00eda","year":"2012","journal-title":"ISRN Pharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0205","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1645\/GE-1675.1","article-title":"Leishmanicidal activity of Yucatecan medicinal plants on Leishmania species responsible for cutaneous leishmaniasis","volume":"95","author":"Getti","year":"2009","journal-title":"J. Parasitol."},{"key":"10.1016\/j.exppara.2014.05.004_b0210","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1007\/s00436-011-2638-3","article-title":"Antileishmanial, antitrypanosomal, and cytotoxic screening of ethnopharmacologically selected Peruvian plants","volume":"110","author":"Gonz\u00e1lez-Coloma","year":"2011","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2014.05.004_b0215","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1128\/CMR.6.3.230","article-title":"Leishmaniases of the new world: current conceptions and implications for future research","volume":"6","author":"Grimaldi","year":"1993","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.exppara.2014.05.004_b0220","doi-asserted-by":"crossref","first-page":"4547","DOI":"10.1016\/S0040-4020(01)86461-9","article-title":"HIV inhibitory natural products. 3. Diterpenes from Homalantus acuminatus and Chrysobalamus icaco","volume":"47","author":"Gustafson","year":"1991","journal-title":"Tetrahedron"},{"key":"10.1016\/j.exppara.2014.05.004_b0225","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1016\/j.phytochem.2007.09.009","article-title":"Vegetable tannins \u2013 lessons of a phytochemical lifetime","volume":"68","author":"Haslam","year":"2007","journal-title":"Phytochemistry"},{"key":"10.1016\/j.exppara.2014.05.004_b0230","doi-asserted-by":"crossref","first-page":"599","DOI":"10.2174\/092986709787458489","article-title":"Leishmaniasis: current treatment and prospect for new drugs and vaccines","volume":"16","author":"Kedzierski","year":"2009","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.exppara.2014.05.004_b0235","series-title":"Encyclopedia of Indian Medicinal Plants","first-page":"207","author":"Khare","year":"2004"},{"key":"10.1016\/j.exppara.2014.05.004_b0240","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1016\/j.phytochem.2005.01.011","article-title":"Antileishmanial activity and immune modulatory efects of tannins and related compounds on leishmania parasitized RAW 264.7 cells","volume":"66","author":"Kolodziej","year":"2005","journal-title":"Phytochemistry"},{"key":"10.1016\/j.exppara.2014.05.004_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/304354","article-title":"Strychnos pseudoquina and its purified compounds present an effective in vitro antileishmanial activity","volume":"2013","author":"Lage","year":"2013","journal-title":"Evidence-Based Complement. Altern. Med."},{"key":"10.1016\/j.exppara.2014.05.004_b0250","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/j.foodres.2011.04.027","article-title":"Ellagitannins, ellagic acid and their derived metabolites: a review about source, metabolism, functions and health","volume":"44","author":"Landete","year":"2011","journal-title":"Food Res. Int."},{"key":"10.1016\/j.exppara.2014.05.004_b0255","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jep.2006.10.036","article-title":"In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants","volume":"111","author":"Lenta","year":"2007","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0265","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1472-6882-12-9","article-title":"In vitro and in vivo safety evaluation of Dipteryx alata vogel extract","volume":"12","author":"Lopes","year":"2012","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.exppara.2014.05.004_b0270","series-title":"Plantas Medicinais no Brasil: nativas e ex\u00f3ticas","author":"Lorenzi","year":"2002"},{"key":"10.1016\/j.exppara.2014.05.004_b0275","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.jep.2011.12.014","article-title":"Campomanesia lineatifolia Ruiz & Pav. as a gastroprotective agent","volume":"139","author":"Madalosso","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0280","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S0031-9422(97)01020-0","article-title":"Pharmacology and chemotaxonomy of Diospyros","volume":"49","author":"Mallavadhani","year":"1998","journal-title":"Phytochemistry"},{"key":"10.1016\/j.exppara.2014.05.004_b0285","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1006\/expr.1997.4205","article-title":"Leishmania spp.: mechanisms of toxicity of nitrogen oxidation products","volume":"87","author":"Mau\u00ebl","year":"1997","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2014.05.004_b0290","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1078\/094471102321616463","article-title":"Anti-herpes simplex virus effect of a seed extract from the tropical plant Licania tomentosa (benth.) Fritsch (chrysobalanaceae)","volume":"9","author":"Miranda","year":"2002","journal-title":"Phytomedicine"},{"key":"10.1016\/j.exppara.2014.05.004_b0295","series-title":"Bot\u00e2nica Brasileira: Aplicada \u00e0 Medicina \u00e0s Artes e \u00e0 Ind\u00fastria","author":"Moraes","year":"1881"},{"key":"10.1016\/j.exppara.2014.05.004_b0300","series-title":"Atlas of Medicinal Plants of Middle America. Bahamas to Yucatan","author":"Morton","year":"1981"},{"key":"10.1016\/j.exppara.2014.05.004_b0305","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0378-8741(97)00130-X","article-title":"Screening of anti-diarrhoeal profile of some plant extracts of a specific region of West Bengal: India","volume":"60","author":"Mukherjee","year":"1998","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0310","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/S0140-6736(05)67629-5","article-title":"Advances in leishmaniasis","volume":"366","author":"Murray","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.exppara.2014.05.004_b0315","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1016\/j.phytochem.2006.06.027","article-title":"The antileishmanial activity assessment of unusual flavonoids from Kalanchoe pinnata","volume":"67","author":"Muzitano","year":"2006","journal-title":"Phytochemistry"},{"key":"10.1016\/j.exppara.2014.05.004_b0320","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1021\/np068054v","article-title":"Natural products as sources of new drugs over the last 25years","volume":"70","author":"Newman","year":"2007","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.exppara.2014.05.004_b0325","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jep.2012.06.001","article-title":"Hymenaea stigonocarpa Mart. Ex Hayne: a Brazilian medicinal plant with gastric and duodenal anti-ulcer and anti diarrheal effects in experimental rodent models","volume":"143","author":"Orsi","year":"2012","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0330","series-title":"Plantas que curam: cheiro de mato","author":"Panizza","year":"1997"},{"key":"10.1016\/j.exppara.2014.05.004_b0335","first-page":"354","article-title":"Plants as hypoglycemic agents","volume":"49","author":"Pereira","year":"1997","journal-title":"Ci\u00eancia e Cultura"},{"key":"10.1016\/j.exppara.2014.05.004_b0340","first-page":"91","article-title":"Atividade de abager\u00fa (Chrysobalanus icaco L.) em modelos experimentais para o estudo de plantas hipoglicemiantes","volume":"68","author":"Presta","year":"1987","journal-title":"Braz. J. Pharm."},{"key":"10.1016\/j.exppara.2014.05.004_b0345","doi-asserted-by":"crossref","first-page":"8193","DOI":"10.3390\/molecules15118193","article-title":"Chemical constituents of the bark of Dipteryx alata vogel, an active species against Bothrops jararacussu venom","volume":"15","author":"Puebla","year":"2010","journal-title":"Molecules"},{"key":"10.1016\/j.exppara.2014.05.004_b0350","first-page":"877","article-title":"Novel targeting using nanoparticles: an approach to the development of an effective anti-leishmanial drug delivery system","volume":"14","author":"Ribeiro","year":"2014","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.exppara.2014.05.004_b0355","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.drudis.2007.10.010","article-title":"Plant-derived compounds in clinical trials","volume":"13","author":"Saklani","year":"2008","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.exppara.2014.05.004_b0360","doi-asserted-by":"crossref","first-page":"2806","DOI":"10.1002\/chem.201002662","article-title":"Chemical ecology of tannins: recent developments in tannin chemistry reveal new structures and structure-activity patterns","volume":"17","author":"Salminen","year":"2011","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.exppara.2014.05.004_b0365","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/S0367-326X(02)00131-4","article-title":"Antibacterial activity of Syzygium cumini and Syzygium travancoriceum leaf essential oils","volume":"73","author":"Shafi","year":"2002","journal-title":"Fitoterapia"},{"key":"10.1016\/j.exppara.2014.05.004_b0370","first-page":"279","article-title":"Partial purification and antibacterial studies of extracts from Eugenia jambolana Linn and Vinca rosea Linn Pak","volume":"37","author":"Shaikh","year":"1994","journal-title":"J. Sci. Ind. Res."},{"key":"10.1016\/j.exppara.2014.05.004_b0375","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s00436-009-1554-2","article-title":"Evaluation of antileishmanial activity of selected Indian plants known to have antimicrobial properties","volume":"105","author":"Sharma","year":"2009","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2014.05.004_b0380","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1089\/jmf.2009.0099","article-title":"Antinociceptive activity of aqueous extract of Bowdichia virgilioides in mice","volume":"13","author":"Silva","year":"2010","journal-title":"J. Med. Food"},{"key":"10.1016\/j.exppara.2014.05.004_b0385","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.exppara.2010.10.014","article-title":"Leishmania donovani: assessment of leishmanicidal effects of herbal extracts obtained from plants in the visceral leishmaniasis endemic area of Bihar, India","volume":"127","author":"Singh","year":"2011","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2014.05.004_b0390","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S1995-7645(12)60084-4","article-title":"Leishmaniasis: current status of available drugs and new potential drug targets","volume":"5","author":"Sundar","year":"2012","journal-title":"Asian Pac. J. Trop. Med."},{"key":"10.1016\/j.exppara.2014.05.004_b0395","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1128\/AAC.50.4.1352-1364.2006","article-title":"Antitrypanosomal and leishmanicidal activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies","volume":"50","author":"Tasdemir","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.exppara.2014.05.004_b0400","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1006\/bbrc.2000.4175","article-title":"Bothrops moojeni venom kills Leishmania spp. with hydrogen peroxide generated by its l-amino acid oxidase","volume":"280","author":"Tempone","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.exppara.2014.05.004_b0405","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jep.2009.10.014","article-title":"Antinociceptive and anti-inflammatory activities of Bowdichia virgilioides (sucupira)","volume":"127","author":"Thomazzia","year":"2010","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0410","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.parint.2011.06.001","article-title":"Leishmanicidal activity of the Agaricus blazei Murill in different Leishmania species","volume":"60","author":"Valadares","year":"2011","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.exppara.2014.05.004_b0415","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.exppara.2012.07.005","article-title":"Prophylactic or therapeutic administration of Agaricus blazei Murill is effective in treatment of murine visceral leishmaniasis","volume":"132","author":"Valadares","year":"2012","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2014.05.004_b0420","first-page":"1","article-title":"Therapeutic efficacy induced by the oral administration of Agaricus blazei Murill against Leishmania amazonensis","volume":"113","author":"Valadares","year":"2012","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2014.05.004_b0425","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1590\/S0100-40422009000500031","article-title":"Derivados oleananos e ursanos e sua import\u00e2ncia na descoberta de novos f\u00e1rmacos com atividade antitumoral, anti-inflamat\u00f3ria e antioxidante","volume":"32","author":"Vechia","year":"2009","journal-title":"Quim. Nova"},{"key":"10.1016\/j.exppara.2014.05.004_b0430","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0367-326X(02)00293-9","article-title":"Antioxidant activity of Paraguayan plant extracts","volume":"74","author":"Vel\u00e1zquez","year":"2003","journal-title":"Fitoterapia"},{"key":"10.1016\/j.exppara.2014.05.004_b0435","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1016\/j.fct.2012.05.002","article-title":"Essential oil of the leaves of Eugenia uniflora l.: antioxidant and antimicrobial properties","volume":"50","author":"Victoria","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.exppara.2014.05.004_b0440","series-title":"Plant Drug Analysis: A Thin Layer Chromatography Atlas","author":"Wagner","year":"1984"},{"key":"10.1016\/j.exppara.2014.05.004_b0445","volume":"vol. III","author":"Watt","year":"1956"},{"key":"10.1016\/j.exppara.2014.05.004_b0450","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0378-8741(01)00346-4","article-title":"Antiprotozoal activities of Colombian plants","volume":"78","author":"Weniger","year":"2001","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.exppara.2014.05.004_b0455","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/ptr.2650040402","article-title":"Natural products and the development of selective antiprotozoal drugs","volume":"4","author":"Wright","year":"1990","journal-title":"Phytother. Res."},{"key":"10.1016\/j.exppara.2014.05.004_b0460","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.exppara.2012.06.012","article-title":"Evaluation of antileishmanial activity of South Indian medicinal plants against Leishmania donovani","volume":"132","author":"Zahir","year":"2012","journal-title":"Exp. Parasitol."}],"container-title":["Experimental Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489414001180?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489414001180?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T19:24:23Z","timestamp":1649013863000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014489414001180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":91,"alternative-id":["S0014489414001180"],"URL":"https:\/\/doi.org\/10.1016\/j.exppara.2014.05.004","relation":{},"ISSN":["0014-4894"],"issn-type":[{"value":"0014-4894","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antileishmanial activity and cytotoxicity of Brazilian plants","name":"articletitle","label":"Article Title"},{"value":"Experimental Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exppara.2014.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}