{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T02:10:30Z","timestamp":1788401430676,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004901","name":"FAPEMIG","doi-asserted-by":"crossref","award":["APQ 0171\/11"],"award-info":[{"award-number":["APQ 0171\/11"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004901","name":"FAPEMIG","doi-asserted-by":"crossref","award":["BPD 00284-14"],"award-info":[{"award-number":["BPD 00284-14"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004901","name":"FAPEMIG","doi-asserted-by":"crossref","award":["APQ 02015\/14"],"award-info":[{"award-number":["APQ 02015\/14"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"crossref","award":["487221\/2012-5"],"award-info":[{"award-number":["487221\/2012-5"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"crossref","award":["478430\/2013-2"],"award-info":[{"award-number":["478430\/2013-2"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"crossref","award":["00\/11624-5"],"award-info":[{"award-number":["00\/11624-5"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]},{"name":"PIBIC\/CNPq\/UFJF"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Parasitology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.exppara.2015.09.015","type":"journal-article","created":{"date-parts":[[2015,10,21]],"date-time":"2015-10-21T00:52:23Z","timestamp":1445388743000},"page":"207-214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["Schistosomicidal activity and docking of Schistosoma mansoni ATPDase 1 with licoflavone B isolated from Glycyrrhiza inflata (Fabaceae)"],"prefix":"10.1016","volume":"159","author":[{"given":"Lara Soares","family":"Aleixo de Carvalho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reinaldo Barros","family":"Geraldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josu\u00e9","family":"de Moraes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Luiz","family":"Silva Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscila","family":"de Faria Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Olavo dos Santos","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9096-1336","authenticated-orcid":false,"given":"Ademar A.","family":"Da Silva Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.exppara.2015.09.015_bib1","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1016\/S0031-9422(00)91021-5","article-title":"Biosynthesis of a retrochalcone, echinatin: involvement of O-methyltransferase to licodione","volume":"19","author":"Ayabe","year":"1980","journal-title":"Phytochemistry"},{"key":"10.1016\/j.exppara.2015.09.015_bib2","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1093\/bioinformatics\/btq662","article-title":"Toward the estimation of the absolute quality of individual protein structure models","volume":"27","author":"Benkert","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.exppara.2015.09.015_bib3","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1002\/cbdv.201100167","article-title":"Chemical composition and in\u00a0vitro schistosomicidal activity of the essential oil of Plectranthus neochilus grown in Southeast Brazil","volume":"8","author":"Caixeta","year":"2011","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.exppara.2015.09.015_bib4","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1017\/S0022149X13000205","article-title":"In\u00a0vitro schistosomicidal effects of aqueous and dichloromethane fractions from leaves and stems of Piper species and the isolation of an active amide from P.\u00a0amalago L. (Piperaceae)","volume":"88","author":"Carrara","year":"2013","journal-title":"J.\u00a0Helminthol."},{"key":"10.1016\/j.exppara.2015.09.015_bib5","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s11302-014-9416-5","article-title":"Schistosome apyrase SmATPDase1, but not SmATPDase2, hydrolyses exogenous ATP and ADP","volume":"10","author":"Da'dara","year":"2014","journal-title":"Purinergic. Signal"},{"key":"10.1016\/j.exppara.2015.09.015_bib6","series-title":"Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components","first-page":"109","article-title":"Natural products with activity against Schistosoma species","author":"De Castro","year":"2013"},{"key":"10.1016\/j.exppara.2015.09.015_bib7","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.exppara.2012.07.004","article-title":"Schistosoma mansoni: in\u00a0vitro schistosomicidal activity schistosomicidal activity and tegumental alterations induced by piplartine on schistosomula","volume":"132","author":"De Moraes","year":"2012","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2015.09.015_bib8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/978-3-319-12418-6_12","article-title":"Structural comparative analysis of secreted NTPDase models of Schistosoma mansoni and Homo sapiens","volume":"8826","author":"De Souza","year":"2014","journal-title":"Lect. Notes. Comput. Sci."},{"key":"10.1016\/j.exppara.2015.09.015_bib9","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/S0006-291X(03)01268-3","article-title":"Molecular characterization and immunolocalization of Schistosoma mansoni ATP-diphosphohydrolase","volume":"307","author":"DeMarco","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.exppara.2015.09.015_bib10","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1017\/S0031182004005244","article-title":"ATP diphosphohydrolase from Schistosoma mansoni egg: characterization and immunocytochemical localization of a new antigen","volume":"129","author":"Faria-Pinto","year":"2004","journal-title":"Parasitol"},{"key":"10.1016\/j.exppara.2015.09.015_bib11","doi-asserted-by":"crossref","first-page":"730","DOI":"10.5551\/jat.3293","article-title":"Antiplatelet activity and structure-activity relationship study of pyrazolopyridine derivatives as potential series for treating thrombotic diseases","volume":"17","author":"Geraldo","year":"2010","journal-title":"J.\u00a0Atheroscler. Thromb."},{"key":"10.1016\/j.exppara.2015.09.015_bib12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1155\/2014\/460342","article-title":"Anthelmintic activity of crude extract and essential oil of Tanacetum vulgare (Asteraceae) against adult worms of Schistosoma mansoni","volume":"2014","author":"Godinho","year":"2014","journal-title":"Sci. World. J."},{"key":"10.1016\/j.exppara.2015.09.015_bib13","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0968-0896(97)10034-7","article-title":"Antioxidative and superoxide scavenging activities of retrochalcones in Glycyrrhiza inflata","volume":"6","author":"Haraguchi","year":"1998","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.exppara.2015.09.015_bib14","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1016\/0031-9422(92)83481-D","article-title":"Two prenylated retrochalcones from Glycyrrhiza inflata","volume":"31","author":"Kajiyama","year":"1992","journal-title":"Phytochemistry"},{"key":"10.1016\/j.exppara.2015.09.015_bib15","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1107\/S0021889892009944","article-title":"Procheck \u2013 a program to check the stereochemical quality of protein structures","volume":"26","author":"Laskowski","year":"1993","journal-title":"J.\u00a0Appl. Crystallogr."},{"key":"10.1016\/j.exppara.2015.09.015_bib16","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1007\/s00436-008-1311-y","article-title":"In\u00a0vitro schistosomicidal activity of curcumin against Schistosoma mansoni adult worms","volume":"104","author":"Magalh\u00e3es","year":"2009","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2015.09.015_bib17","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s00436-009-1674-8","article-title":"In\u00a0vitro schistosomicidal effects of some phloroglucinol derivatives from Dryopteris species against Schistosoma mansoni adult worms","volume":"106","author":"Magalh\u00e3es","year":"2010","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2015.09.015_bib18","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1017\/S0031182009990965","article-title":"Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni","volume":"137","author":"Manneck","year":"2010","journal-title":"Parasitology"},{"key":"10.1016\/j.exppara.2015.09.015_bib19","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1023\/A:1010330017583","article-title":"Inhibition of the Ecto-ATPdiphosphohydrolase of Schistosoma mansoni by Thapsigargin","volume":"20","author":"Martins","year":"2000","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.exppara.2015.09.015_bib20","series-title":"Current Topics in Tropical Medicine","first-page":"333","article-title":"Antischistosomal natural compounds: present challenges for new drug screens","author":"Moraes","year":"2012"},{"key":"10.1016\/j.exppara.2015.09.015_bib21","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.exppara.2010.08.021","article-title":"Schistosoma mansoni: in\u00a0vitro schistosomicidal activity of piplartine","volume":"127","author":"Moraes","year":"2011","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2015.09.015_bib22","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/(SICI)1096-987X(19981115)19:14<1639::AID-JCC10>3.0.CO;2-B","article-title":"Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function","volume":"19","author":"Morris","year":"1998","journal-title":"J.\u00a0Comput. Chem."},{"key":"10.1016\/j.exppara.2015.09.015_bib23","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/0960-894X(95)00053-V","article-title":"Synthesis of antiparasitic licorice chalcones","volume":"5","author":"Nielsen","year":"1995","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.exppara.2015.09.015_bib24","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ejmech.2006.09.019","article-title":"A\u00a0review of anti-infective and anti-inflammatory chalcones","volume":"42","author":"Nowakowska","year":"2007","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.exppara.2015.09.015_bib25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.exppara.2012.06.005","article-title":"Schistosoma mansoni: in\u00a0vitro schistosomicidal activity of essential oil of Baccharis trimera (less) DC","volume":"132","author":"Oliveira","year":"2012","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2015.09.015_bib26","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.exppara.2014.02.010","article-title":"Anthelmintic activity in\u00a0vitro and in\u00a0vivo of Baccharis trimera (Less) DC against immature and adult worms of Schistosoma mansoni","volume":"139","author":"Oliveira","year":"2014","journal-title":"Exp. Parasitol"},{"key":"10.1016\/j.exppara.2015.09.015_bib27","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejphar.2007.05.028","article-title":"A\u00a0new series of schistosomicide drugs, the alkylaminoalkanethiosulfuric acids, partially inhibit the activity of Schistosoma mansoni ATP diphosphohydrolase","volume":"570","author":"Penido","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.exppara.2015.09.015_bib28","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1055\/s-0032-1327832","article-title":"In\u00a0vitro schistosomicidal activity of balsaminol F and karavilagenin C","volume":"78","author":"Ramalhete","year":"2012","journal-title":"Planta. Med."},{"key":"10.1016\/j.exppara.2015.09.015_bib29","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1590\/S0102-695X2011005000202","article-title":"In\u00a0vitro schistosomicidal effects of the essential oil of Tagetes erecta","volume":"22","author":"Tonuci","year":"2012","journal-title":"Rev. Bras. Farmacogn."},{"key":"10.1016\/j.exppara.2015.09.015_bib30","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0166-6851(93)90042-V","article-title":"Characterization and localization of an ATP-diphosphohydrolase on the external surface of the tegument of Schistosoma mansoni","volume":"58","author":"Vasconcelos","year":"1993","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.exppara.2015.09.015_bib31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.abb.2008.11.023","article-title":"Integrin inhibitors from snake venom: exploring the relationship between the structure and activity of RGD-peptides","volume":"482","author":"Wermelinger","year":"2009","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.exppara.2015.09.015_bib32","series-title":"Neglected Tropical Diseases","author":"WHO","year":"2015"},{"key":"10.1016\/j.exppara.2015.09.015_bib33","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1017\/S0031182000007137","article-title":"Praziquantel-induced tegumental damage in\u00a0vitro is diminished in schistosomes derived from praziquantel-resistant infections","volume":"122","author":"William","year":"2001","journal-title":"Parasitology"},{"key":"10.1016\/j.exppara.2015.09.015_bib34","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1248\/cpb.53.694","article-title":"Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata","volume":"53","author":"Yoon","year":"2005","journal-title":"Chem. Pharm. Bull."}],"container-title":["Experimental Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489415300497?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489415300497?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,18]],"date-time":"2018-09-18T11:20:48Z","timestamp":1537269648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014489415300497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":34,"alternative-id":["S0014489415300497"],"URL":"https:\/\/doi.org\/10.1016\/j.exppara.2015.09.015","relation":{},"ISSN":["0014-4894"],"issn-type":[{"value":"0014-4894","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Schistosomicidal activity and docking of Schistosoma mansoni ATPDase 1 with licoflavone B isolated from Glycyrrhiza inflata (Fabaceae)","name":"articletitle","label":"Article Title"},{"value":"Experimental Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exppara.2015.09.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}