{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:22:05Z","timestamp":1777418525389,"version":"3.51.4"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100006087","name":"DGAPA, UNAM","doi-asserted-by":"publisher","award":["IN-216213"],"award-info":[{"award-number":["IN-216213"]}],"id":[{"id":"10.13039\/501100006087","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","award":["471009\/2013-0"],"award-info":[{"award-number":["471009\/2013-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Parasitology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.exppara.2016.11.002","type":"journal-article","created":{"date-parts":[[2016,11,21]],"date-time":"2016-11-21T19:47:19Z","timestamp":1479757639000},"page":"12-17","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["A benzimidazole derivative (RCB20) in\u00a0vitro induces an activation of energetic pathways on Taenia crassiceps (ORF strain) cysticerci"],"prefix":"10.1016","volume":"172","author":[{"given":"Carolina Miguel","family":"Fraga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiane Luiza","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Maria","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Reynoso-Ducoing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Ambrosio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alicia","family":"Hern\u00e1ndez-Campos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina Clare","family":"Vinaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.exppara.2016.11.002_bib1","doi-asserted-by":"crossref","first-page":"6208","DOI":"10.1016\/j.bmc.2012.09.013","article-title":"The therapeutic journey of benzimidazoles: a review","volume":"20","author":"Bansai","year":"2012","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.exppara.2016.11.002_bib2","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.vetpar.2013.09.023","article-title":"Generalized Taenia crassiceps cysticercosis in a chinchila (Chinchilla lanigera)","volume":"199","author":"Basso","year":"2014","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib3","doi-asserted-by":"crossref","DOI":"10.14411\/fp.2015.023","article-title":"Screening for anthelmintic resistance in equid strongyles (Nematoda) in Romania","volume":"62","author":"Cernea","year":"2015","journal-title":"Folia Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib4","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1007\/s00436-010-1997-5","article-title":"Liver fluke \u03b2-tubulin isotype 2 binds albendazole and is thus a probable target of this drug","volume":"107","author":"Chambers","year":"2010","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2016.11.002_bib5","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.ijpara.2015.04.007","article-title":"Genetic evidence for the spread of a benzimidazole resistance mutation across southern India from a single origin in the parasitic nematode Haemonchus contortus","volume":"45","author":"Chaudhry","year":"2015","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib6","first-page":"84516","article-title":"Metabolism of [3-13C]-pyruvate by cysticerci of Taenia crassiceps","author":"Corbin","year":"1998","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2016.11.002_bib7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.parint.2005.04.003","article-title":"Cyanide-resistant respiration in Taenia crassiceps metacestode (cysticerci) is explained by the H2O2-producing side-reaction of respiratory complex I with O2","volume":"54","author":"Del Arenal","year":"2005","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.exppara.2016.11.002_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.exppara.2012.03.017","article-title":"Fatty acids oxidation and alternative energy sources detected in Taenia crassiceps cysticerci after host treatment with antihelminthic drugs","volume":"131","author":"Fraga","year":"2012","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.exppara.2011.11.001","article-title":"Taenia crassiceps: host treatment alters glycolisis and tricarboxilic acid cycle in cysticerci","volume":"130","author":"Fraga","year":"2012","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib10","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1139\/z62-086","article-title":"Studies on the biology of Taenia crassiceps (Zeder 1800) Rudolphi, 1810 (Cestoda)","volume":"40","author":"Freeman","year":"1962","journal-title":"Can. J. Zool."},{"key":"10.1016\/j.exppara.2016.11.002_bib11","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1023\/A:1023391312659","article-title":"Albendazole resistance in gastrointestinal nematode parasites of cattle in Bangladesh","volume":"35","author":"Hoque","year":"2003","journal-title":"Trop. Anim. Health. Prod."},{"key":"10.1016\/j.exppara.2016.11.002_bib12","doi-asserted-by":"crossref","first-page":"S113","DOI":"10.1017\/S0031182000007290","article-title":"Albendazole: a review of anthelmintic efficacy and safety in humans","volume":"121","author":"Horton","year":"2000","journal-title":"Parasitology"},{"key":"10.1016\/j.exppara.2016.11.002_bib13","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.pt.2009.04.004","article-title":"Drug resistance mechanism in helminths: is it survival of the fittest?","volume":"25","author":"James","year":"2009","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib14","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.vetpar.2015.02.005","article-title":"Rapid selection for \u03b2-tubulin alleles in codon 200 conferring benzimidazole resistance in an Ostertagia ostertagi isolate on pasture","volume":"209","author":"Knapp-Lawitzke","year":"2015","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib15","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1007\/s00436-013-3379-2","article-title":"RCB20, an experimental benzimidazole derivative, affects tubulin expression and induces gross anatomical changes in Taenia crassiceps cysticerci","volume":"112","author":"M\u00e1rquez-Navarro","year":"2013","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2016.11.002_bib16","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1007\/s11250-015-0826-3","article-title":"Anthelmintic resistance in gastrointestinal nematodes from grazing beef cattle in Campeche State, Mexico","volume":"47","author":"Mu\u00f1iz-Lagunes","year":"2015","journal-title":"Trop. Anim. Health. Prod."},{"issue":"Pt 8","key":"10.1016\/j.exppara.2016.11.002_bib17","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1017\/S003118200700008X","article-title":"Markers for benzimidazole resistance in human parasitic nematodes?","volume":"134","author":"Prichard","year":"2007","journal-title":"Parasitology"},{"key":"10.1016\/j.exppara.2016.11.002_bib18","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1007\/s00436-008-0917-4","article-title":"Glucose 6-phosphate dehydrogenase from larval Taenia crassiceps (cysticerci): purification and properties","volume":"102","author":"Rend\u00f3n","year":"2008","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2016.11.002_bib19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.molbiopara.2003.09.003","article-title":"Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci)","volume":"133","author":"Rend\u00f3n","year":"2004","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib20","doi-asserted-by":"crossref","first-page":"e1417","DOI":"10.1371\/journal.pntd.0001417","article-title":"Low efficacy of single-dose albendazole and mebendazole against hookworm and effect on concomitant helminth infection in Lao PDR","volume":"6","author":"Soukhathammavong","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.exppara.2016.11.002_bib21","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.2217\/fmb.15.73","article-title":"Overcoming drug resistance for macro parasites","volume":"10","author":"Srivastava","year":"2015","journal-title":"Future Microbiol."},{"key":"10.1016\/j.exppara.2016.11.002_bib22","doi-asserted-by":"crossref","first-page":"354","DOI":"10.4269\/ajtmh.1997.57.354","article-title":"Immunoblot with cerebrospinal fluid from patients with neurocysticercosis using antigen from cysticerci of Taenia solium and Taenia crassiceps","volume":"57","author":"Vaz","year":"1997","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.exppara.2016.11.002_bib23","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.exppara.2008.07.008","article-title":"Taenia crassiceps: energetic and respiratory metabolism from cysticerci exposed to praziquantel and albendazole in\u00a0vitro","volume":"120","author":"Vinaud","year":"2008","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib24","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.exppara.2009.03.015","article-title":"Taenia crassiceps: fatty acids oxidation and alternative energy source in in\u00a0vitro cysticerci exposed to anthelminthic drugs","volume":"122","author":"Vinaud","year":"2009","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib25","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.exppara.2007.01.013","article-title":"Taenia crassiceps organic acids detected in cysticerci","volume":"116","author":"Vinaud","year":"2007","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.exppara.2016.11.002_bib26","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1007\/s00436-005-1348-0","article-title":"Taeniid tapeworm responses to in\u00a0vitro glucose","volume":"96","author":"Willms","year":"2005","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.exppara.2016.11.002_bib27","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1017\/S0031182009991442","article-title":"Taenia crassiceps: in\u00a0vivo and in\u00a0vitro models","volume":"137","author":"Willms","year":"2010","journal-title":"Parasitology"}],"container-title":["Experimental Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489416303265?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014489416303265?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,6]],"date-time":"2018-09-06T14:24:46Z","timestamp":1536243886000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014489416303265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":27,"alternative-id":["S0014489416303265"],"URL":"https:\/\/doi.org\/10.1016\/j.exppara.2016.11.002","relation":{},"ISSN":["0014-4894"],"issn-type":[{"value":"0014-4894","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A benzimidazole derivative (RCB20) in\u00a0vitro induces an activation of energetic pathways on Taenia crassiceps (ORF strain) cysticerci","name":"articletitle","label":"Article Title"},{"value":"Experimental Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exppara.2016.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}