{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:34:27Z","timestamp":1791286467398,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Parasitology"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.exppara.2022.108217","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T20:46:32Z","timestamp":1643057192000},"page":"108217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The association of IL-3, IL-17A, and IL 27 serum levels with susceptibility to toxoplasmosis in recurrent abortion of Iraqi women"],"prefix":"10.1016","volume":"234","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8285-2693","authenticated-orcid":false,"given":"Noor Nihad","family":"Baqer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Entsar Jabbar","family":"Saheb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najwa Shihab","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najah Abdulnabi","family":"Ali Alhadad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.exppara.2022.108217_bib1","doi-asserted-by":"crossref","first-page":"112","DOI":"10.5001\/omj.2013.29","article-title":"Interleukin-10 serum levels after vaccination with in vivo prepared Toxoplasma gondii excreted\/secreted antigens","volume":"28","author":"Abdollahi","year":"2013","journal-title":"Oman Med. J."},{"issue":"7","key":"10.1016\/j.exppara.2022.108217_bib2","doi-asserted-by":"crossref","first-page":"857","DOI":"10.4088\/JCP.15f10150","article-title":"Understanding relative risk, odds ratio, and related terms: as simple as it can get","volume":"76","author":"Andrade","year":"2015","journal-title":"J. Clin. Psychiatr."},{"issue":"3A","key":"10.1016\/j.exppara.2022.108217_bib33","first-page":"1189","article-title":"The Association of severe toxoplasmosis and some cytokine levels in breast cancer patients","volume":"59","author":"Assim","year":"2018","journal-title":"Iraqi J. Sci."},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib3","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1471-2334-14-33","article-title":"Congenital toxoplasmosis and prenatal care state programs","volume":"14","author":"Avelino","year":"2014","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.exppara.2022.108217_bib4","series-title":"Maternal, Fetal, & Neonatal Physiology4: Maternal, Fetal","author":"Blackburn","year":"2012"},{"key":"10.1016\/j.exppara.2022.108217_bib5","series-title":"Maternal, Fetal, & Neonatal Physiology-E-Book: a Clinical Perspective","author":"Blackburn","year":"2017"},{"key":"10.1016\/j.exppara.2022.108217_bib6","series-title":"Recurrent Pregnancy Loss: Causes, Controversies, and Treatment","first-page":"422","author":"Carp","year":"2015"},{"issue":"7","key":"10.1016\/j.exppara.2022.108217_bib7","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1016\/j.cellsig.2010.11.022","article-title":"Signaling of interleukin-17 family cytokines in immunity and inflammation","volume":"23","author":"Chang","year":"2011","journal-title":"Cell. Signal."},{"issue":"4","key":"10.1016\/j.exppara.2022.108217_bib8","doi-asserted-by":"crossref","first-page":"243","DOI":"10.12717\/DR.2015.19.4.243","article-title":"Th 17 cells and Nesfatin-1 are associated with spontaneous abortion in the CBA\/j\u00d7 DBA\/2 mouse model","volume":"19","author":"Chung","year":"2015","journal-title":"Dev. Reprod."},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib9","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S1995-7645(11)60024-2","article-title":"Cytokine profile in murine toxoplasmosis","volume":"4","author":"Dogruman-Al","year":"2011","journal-title":"Asian Pac. J. Trop. Med."},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s43042-019-0006-5","article-title":"Toxoplasmosis and abortion: pro- and anti-inflammatory cytokines gene expression of the host immune cells","volume":"20","author":"El-Sherbini","year":"2019","journal-title":"Egypt. J. Med. Hum. Genet."},{"issue":"3","key":"10.1016\/j.exppara.2022.108217_bib11","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/aji.12303","article-title":"Fetal sex\u2010based differences in maternal hormones, angiogenic factors, and immune mediators during pregnancy and the postpartum period","volume":"73","author":"Enninga","year":"2015","journal-title":"Am. J. Reprod. Immunol."},{"issue":"7","key":"10.1016\/j.exppara.2022.108217_bib12","doi-asserted-by":"crossref","first-page":"3225","DOI":"10.4049\/jimmunol.1200141","article-title":"Independent and interdependent immunoregulatory effects of IL-27, IFN-\u03b2, and IL-10 in the suppression of human Th17 cells and murine experimental autoimmune encephalomyelitis","volume":"190","author":"Fitzgerald","year":"2013","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.exppara.2022.108217_bib13","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.immuni.2012.03.024","article-title":"Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1","volume":"36","author":"Hirahara","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.exppara.2022.108217_bib14","first-page":"40","article-title":"Study the correlation between cytokines (IL-6, IL-27, TGF-Beta and IFN-Gamma) levels and microbial abortion among woman in Thi-Qar Province","volume":"13","author":"Kadhim","year":"2020","journal-title":"Int. J. Innovat. Biol. Chem. Sci."},{"issue":"2","key":"10.1016\/j.exppara.2022.108217_bib15","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/aji.12234","article-title":"Immunological modes of pregnancy loss: inflammation, immune effectors, and stress","volume":"72","author":"Kwak\u2010Kim","year":"2014","journal-title":"Am. J. Reprod. Immunol."},{"issue":"5","key":"10.1016\/j.exppara.2022.108217_bib16","first-page":"299","article-title":"Peculiarities of the content of peripheral blood cytokines in pregnant women with a habitual miscarriage","volume":"65","author":"Malyshkina","year":"2020"},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib17","first-page":"239","article-title":"The role T-helper-17 in toxoplasmosis among women with abortion","volume":"15","author":"Mohammed","year":"2012","journal-title":"KUFA Med. J."},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.9734\/ijtdh\/2020\/v41i130247","article-title":"Immunochromatographic tests in diagnosis of toxoplasmosis in Port Harcourt, Nigeria","volume":"41","author":"Onosakponome","year":"2020","journal-title":"Int. J. Trop. Dis. Health"},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib19","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S1701-2163(15)31053-7","article-title":"Toxoplasmosis in pregnancy: prevention, screening, and treatment","volume":"35","author":"Paquet","year":"2013","journal-title":"J. Obstet. Gynaecol. Can."},{"issue":"8","key":"10.1016\/j.exppara.2022.108217_bib20","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1128\/IAI.00283-16","article-title":"Interleukin-27 (IL-27) mediates susceptibility to visceral leishmaniasis by suppressing the IL-17\u2013neutrophil response","volume":"84","author":"Quirino","year":"2016","journal-title":"Infect. Immun."},{"issue":"9\u201310","key":"10.1016\/j.exppara.2022.108217_bib21","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.cca.2011.01.002","article-title":"Cytokines in recurrent pregnancy loss","volume":"412","author":"Saini","year":"2011","journal-title":"Clin. Chim. Acta"},{"issue":"6","key":"10.1016\/j.exppara.2022.108217_bib22","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/j.1600-0897.2010.00852.x","article-title":"Th1\/Th2\/Th17 and regulatory T\u2010cell paradigm in pregnancy","volume":"63","author":"Saito","year":"2010","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.exppara.2022.108217_bib23","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/764369","article-title":"Seroprevalence of Toxoplasma gondii in women who have aborted in comparison with the women with normal delivery in Ahvaz, southwest of Iran","author":"Saki","year":"2015","journal-title":"TheScientificWorldJOURNAL"},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib24","first-page":"59","article-title":"Variations in T-helper 17 and regulatory T cells during the menstrual cycle in peripheral blood of women with recurrent spontaneous abortion","volume":"8","author":"Sereshki","year":"2014","journal-title":"Int. J. Fertil. Steril."},{"key":"10.1016\/j.exppara.2022.108217_bib25","doi-asserted-by":"crossref","DOI":"10.1051\/parasite\/2020006","article-title":"Serological diagnosis of Toxoplasma gondii: analysis of false-positive IgG results and implications","volume":"27","author":"Simon","year":"2020","journal-title":"Parasite"},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib26","doi-asserted-by":"crossref","DOI":"10.7243\/2050-0874-1-9","article-title":"Diagnosis of toxoplasmosis in pregnancy: a review","volume":"1","author":"Tekkesin","year":"2012","journal-title":"HOAJ Biol."},{"issue":"2","key":"10.1016\/j.exppara.2022.108217_bib27","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jri.2009.12.003","article-title":"Increased prevalence of T helper 17 (Th17) cells in peripheral blood and decidua in unexplained recurrent spontaneous abortion patients","volume":"84","author":"Wang","year":"2010","journal-title":"J. Reprod. Immunol."},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1477-7827-12-74","article-title":"Alteration of Th17 and Treg cells in patients with unexplained recurrent spontaneous abortion before and after lymphocyte immunization therapy","volume":"12","author":"Wu","year":"2014","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"6","key":"10.1016\/j.exppara.2022.108217_bib29","doi-asserted-by":"crossref","first-page":"995","DOI":"10.3390\/ijerph16060995","article-title":"Interleukin-3 polymorphism is associated with miscarriage of fresh in vitro fertilization cycles","volume":"16","author":"Wu","year":"2019","journal-title":"Int. J. Environ. Res. Publ. Health"},{"issue":"1","key":"10.1016\/j.exppara.2022.108217_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0169891","article-title":"Association between genetic polymorphisms in interleukin genes and recurrent pregnancy loss\u2013a systematic review and meta-analysis","volume":"12","author":"Zhang","year":"2017","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.exppara.2022.108217_bib31","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1177\/1933719116670517","article-title":"Treg\/Th17 cell imbalance and IL-6 profile in patients with unexplained recurrent spontaneous abortion","volume":"24","author":"Zhu","year":"2017","journal-title":"Reprod. Sci."}],"container-title":["Experimental Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448942200011X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448942200011X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T06:03:33Z","timestamp":1762149813000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001448942200011X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":32,"alternative-id":["S001448942200011X"],"URL":"https:\/\/doi.org\/10.1016\/j.exppara.2022.108217","relation":{},"ISSN":["0014-4894"],"issn-type":[{"value":"0014-4894","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The association of IL-3, IL-17A, and IL 27 serum levels with susceptibility to toxoplasmosis in recurrent abortion of Iraqi women","name":"articletitle","label":"Article Title"},{"value":"Experimental Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.exppara.2022.108217","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108217"}}