{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T06:24:24Z","timestamp":1792563864267,"version":"4.5.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Foot and Ankle Surgery"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.fas.2021.07.009","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T17:48:25Z","timestamp":1626889705000},"page":"550-556","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Periprosthetic ankle infection: eradication rate, complications, and limb salvage. A systematic review"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8742-5612","authenticated-orcid":false,"given":"Michele","family":"Mercurio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3207-6651","authenticated-orcid":false,"given":"Davide","family":"Castioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvira","family":"Porco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3453-2043","authenticated-orcid":false,"given":"Filippo","family":"Familiari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Gasparini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olimpio","family":"Galasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fas.2021.07.009_bib0005","doi-asserted-by":"crossref","DOI":"10.1007\/s00264-021-05053-x","article-title":"End-stage ankle osteoarthritis: arthroplasty offers better quality of life than arthrodesis with similar complication and re-operation rates\u2014an updated meta-analysis of comparative studies","author":"Fanelli","year":"2021","journal-title":"Int Orthop"},{"key":"10.1016\/j.fas.2021.07.009_bib0010","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.fas.2019.07.006","article-title":"Outcome after total ankle arthroplasty with a minimum of five years follow-up: a systematic review and meta-analysis","volume":"26","author":"Onggo","year":"2020","journal-title":"Foot Ankle Surg"},{"key":"10.1016\/j.fas.2021.07.009_bib0015","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1053\/j.jfas.2017.09.006","article-title":"Patient-related risk factors for periprosthetic ankle joint infection: an analysis of 6977 total ankle arthroplasties","volume":"57","author":"Althoff","year":"2018","journal-title":"J Foot Ankle Surg"},{"key":"10.1016\/j.fas.2021.07.009_bib0020","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1302\/0301-620X.96B6.33298","article-title":"The treatment and outcome of peri-prosthetic infection of the ankle: a single cohort-centre experience of 34 cases","volume":"96-B","author":"Kessler","year":"2014","journal-title":"Bone Jt J"},{"key":"10.1016\/j.fas.2021.07.009_bib0025","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.fcl.2017.01.009","article-title":"How to diagnose and treat infection in total ankle arthroplasty","volume":"22","author":"Alrashidi","year":"2017","journal-title":"Foot Ankle Clin"},{"key":"10.1016\/j.fas.2021.07.009_bib0030","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1016\/S0883-5403(03)00448-0","article-title":"The value of white blood cell counts before revision total knee arthroplasty","volume":"18","author":"Mason","year":"2003","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.fas.2021.07.009_bib0035","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.arth.2014.03.009","article-title":"International consensus group on periprosthetic joint infection. Definition of periprosthetic joint infection","volume":"29","author":"Parvizi","year":"2014","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.fas.2021.07.009_bib0040","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1053\/j.jfas.2019.04.016","article-title":"Clinical effectiveness of treatment strategies for prosthetic joint infection following total ankle replacement: a systematic review and meta-analysis","volume":"59","author":"Kunutsor","year":"2020","journal-title":"J Foot Ankle Surg"},{"key":"10.1016\/j.fas.2021.07.009_bib0045","doi-asserted-by":"crossref","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.fas.2021.07.009_bib0050","article-title":"The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses","author":"Wells","year":"2014","journal-title":"Undefined"},{"key":"10.1016\/j.fas.2021.07.009_bib0055","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0883-5403(92)90049-V","article-title":"Arthrodesis for failed ankle arthroplasty","volume":"7","author":"Kitaoka","year":"1992","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.fas.2021.07.009_bib0060","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/1071100714559272","article-title":"Inferior results of salvage arthrodesis after failed ankle replacement compared to primary arthrodesis","volume":"36","author":"Rahm","year":"2015","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0065","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3113\/FAI.2012.0173","article-title":"Cement spacer as definitive management for postoperative ankle infection","volume":"33","author":"Ferrao","year":"2012","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0070","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1177\/1071100714543643","article-title":"The management of infection following total ankle replacement: demographics and treatment","volume":"35","author":"Myerson","year":"2014","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0075","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1177\/1071100714568869","article-title":"Infected total ankle arthroplasty: risk factors and treatment options","volume":"36","author":"Patton","year":"2015","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0080","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.fas.2018.08.007","article-title":"Ankle fusion after failed ankle replacement in rheumatic and non-rheumatic patients","volume":"25","author":"Kruidenier","year":"2019","journal-title":"Foot Ankle Surg"},{"key":"10.1016\/j.fas.2021.07.009_bib0085","article-title":"Soft-tissue reconstruction of complicated total ankle arthroplasty","author":"Othman","year":"2020","journal-title":"Foot Ankle Spec"},{"key":"10.1016\/j.fas.2021.07.009_bib0090","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1177\/1071100718786164","article-title":"Outcomes of acute hematogenous periprosthetic joint infection in total ankle arthroplasty treated with irrigation, debridement, and polyethylene exchange","volume":"39","author":"Lachman","year":"2018","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0095","doi-asserted-by":"crossref","first-page":"815","DOI":"10.3113\/FAI.2009.0815","article-title":"Analysis of retrieved agility total ankle arthroplasty systems","volume":"30","author":"Vaupel","year":"2009","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0100","doi-asserted-by":"crossref","first-page":"21S","DOI":"10.1177\/1071100719859536","article-title":"What is the diagnostic \u201calgorithm\u201d for infected total ankle arthroplasty (TAA)?","volume":"40","author":"Heidari","year":"2019","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0105","first-page":"159","article-title":"Trends in surgical management of the infected total ankle arthroplasty","volume":"23","author":"Mazzotti","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.fas.2021.07.009_bib0110","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cis803","article-title":"Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America","volume":"56","author":"Osmon","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.fas.2021.07.009_bib0115","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1007\/s00167-016-4010-8","article-title":"Prosthetic knee infection by resistant bacteria: the worst-case scenario","volume":"24","author":"Vasso","year":"2016","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.fas.2021.07.009_bib0120","doi-asserted-by":"crossref","first-page":"24S","DOI":"10.1177\/1071100719859545","article-title":"What are the indications for aspiration of a possibly infected total ankle arthroplasty (TAA)?","volume":"40","author":"Pl\u00f6eger","year":"2019","journal-title":"Foot Ankle Int"},{"key":"10.1016\/j.fas.2021.07.009_bib0125","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.arth.2020.09.030","article-title":"Conversion of fused hip to total hip arthroplasty: long-term clinical and radiological outcomes","volume":"36","author":"Grappiolo","year":"2021","journal-title":"J Arthroplasty"},{"key":"10.1016\/j.fas.2021.07.009_bib0130","doi-asserted-by":"crossref","first-page":"947","DOI":"10.3113\/FAI.2012.0947","article-title":"Circular external fixator-assisted ankle arthrodesis following failed total ankle arthroplasty","volume":"33","author":"McCoy","year":"2012","journal-title":"Foot Ankle Int"}],"container-title":["Foot and Ankle Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S126877312100151X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S126877312100151X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T11:09:18Z","timestamp":1761131358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S126877312100151X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S126877312100151X"],"URL":"https:\/\/doi.org\/10.1016\/j.fas.2021.07.009","relation":{},"ISSN":["1268-7731"],"issn-type":[{"value":"1268-7731","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Periprosthetic ankle infection: eradication rate, complications, and limb salvage. A systematic review","name":"articletitle","label":"Article Title"},{"value":"Foot and Ankle Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fas.2021.07.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}