{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T21:35:56Z","timestamp":1767994556389,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Foundation from the Ministry of Science and Technology of the People\u2019s Republic of China","award":["2006BAD27B08"],"award-info":[{"award-number":["2006BAD27B08"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.fct.2012.03.083","type":"journal-article","created":{"date-parts":[[2012,4,13]],"date-time":"2012-04-13T04:35:38Z","timestamp":1334291738000},"page":"2149-2154","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Corn oligopeptides protect against early alcoholic liver injury in rats"],"prefix":"10.1016","volume":"50","author":[{"given":"Feng","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiali","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2012.03.083_b0005","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.mam.2007.09.004","article-title":"Oxidative mechanisms in the pathogenesis of alcoholic liver disease","volume":"29","author":"Albano","year":"2008","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.fct.2012.03.083_b0010","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1053\/gast.2003.50087","article-title":"Oxidants and antioxidants in alcohol-induced liver disease","volume":"124","author":"Arteel","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.fct.2012.03.083_b0015","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S1521-6918(03)00053-2","article-title":"Advances in alcoholic liver disease","volume":"17","author":"Arteel","year":"2003","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.fct.2012.03.083_b0020","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1515\/bc.2010.137","article-title":"Mechanisms and cell signaling in alcoholic liver disease","volume":"391","author":"Beier","year":"2010","journal-title":"Biol. Chem."},{"key":"10.1016\/j.fct.2012.03.083_b0025","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s11894-010-0157-5","article-title":"Advances in alcoholic liver disease","volume":"13","author":"Beier","year":"2011","journal-title":"Curr. Gastroenterol. Rep."},{"key":"10.1016\/j.fct.2012.03.083_b0030","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jep.2003.11.020","article-title":"Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats","volume":"91","author":"Bhandarkar","year":"2004","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.fct.2012.03.083_b0035","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/j.1365-2036.2010.04371.x","article-title":"Antioxidant supplements for liver diseases","volume":"32","author":"Bjelakovic","year":"2011","journal-title":"Aliment Pharmacol. Ther."},{"key":"10.1016\/j.fct.2012.03.083_b0040","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0140-6736(77)90176-3","article-title":"Alcohol and blood lipids. The cooperative lipoprotein phenotyping study","volume":"2","author":"Castelli","year":"1977","journal-title":"Lancet"},{"key":"10.1016\/j.fct.2012.03.083_b0045","first-page":"173","article-title":"Study on anti-fatigue effect of corn-peptide","volume":"9","author":"Chang","year":"2004","journal-title":"Food Sci."},{"key":"10.1016\/j.fct.2012.03.083_b0050","doi-asserted-by":"crossref","first-page":"G516","DOI":"10.1152\/ajpgi.00537.2010","article-title":"Innate immunity in alcoholic liver disease","volume":"300","author":"Gao","year":"2011","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.fct.2012.03.083_b0055","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1016\/j.fct.2009.06.041","article-title":"Antihepatotoxic effect of corn peptides against Bacillus calmette-guerin\/lipopolysaccharide-induced liver injury in mice","volume":"47","author":"Guo","year":"2009","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.fct.2012.03.083_b0060","series-title":"Subchronic Toxicity Investigation of Ethyl Alcohol: A Test for Lowest Effective Dose (LED) to be used in a Long-Term Bioassay for Carcinogenicity","author":"Holmberg","year":"1986"},{"key":"10.1016\/j.fct.2012.03.083_b0065","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1016\/j.freeradbiomed.2003.09.007","article-title":"The CYP inhibitor 1-aminobenzotriazole does not prevent oxidative stress associated with alcohol-induced liver injury in rats and mice","volume":"35","author":"Isayama","year":"2003","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.fct.2012.03.083_b0070","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.fct.2006.06.025","article-title":"Antioxidant activity of the oyster mushroom, Pleurotus ostreatus, on CCl(4)-induced liver injury in rats","volume":"44","author":"Jayakumar","year":"2006","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.fct.2012.03.083_b0075","doi-asserted-by":"crossref","first-page":"8873","DOI":"10.1016\/j.biortech.2008.04.056","article-title":"Enzymatic preparation of immunomodulating hydrolysates from soy proteins","volume":"99","author":"Kong","year":"2008","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.fct.2012.03.083_b0080","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0891-5849(00)00490-1","article-title":"Ebselen prevents early alcohol-induced liver injury in rats","volume":"30","author":"Kono","year":"2001","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.fct.2012.03.083_b0085","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1042\/BA20060183","article-title":"Preparation of corn (Zea mays) peptides and their protective effect against alcohol-induced acute hepatic injury in NH mice","volume":"47","author":"Li","year":"2007","journal-title":"Biotechnol. Appl. Biochem."},{"key":"10.1016\/j.fct.2012.03.083_b0090","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF02532134","article-title":"Effects of ethanol upon lipid metabolism","volume":"9","author":"Lieber","year":"1974","journal-title":"Lipids"},{"key":"10.1016\/j.fct.2012.03.083_b0095","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.foodchem.2010.06.099","article-title":"Pilot-scale production of low molecular weight peptides from corn wet milling byproducts and the antihypertensive effects in vivo and in vitro","volume":"124","author":"Lin","year":"2011","journal-title":"Food Chem."},{"key":"10.1016\/j.fct.2012.03.083_b0100","first-page":"17","article-title":"Protective effects of shark hepatic stimulator substance against acute hepatic injury induced by acetaminophen in mice","volume":"39","author":"Lu","year":"2004","journal-title":"Yao Xue Xue Bao"},{"key":"10.1016\/j.fct.2012.03.083_b0105","doi-asserted-by":"crossref","first-page":"G497","DOI":"10.1152\/ajpgi.00171.2004","article-title":"Recent advances in alcoholic liver disease. IV. Dysregulated cytokine metabolism in alcoholic liver disease","volume":"287","author":"McClain","year":"2004","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.fct.2012.03.083_b0110","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/hep.23258","article-title":"Alcoholic liver disease","volume":"51","author":"O\u2019Shea","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.fct.2012.03.083_b0115","doi-asserted-by":"crossref","first-page":"30","DOI":"10.2133\/dmpk.DMPK-10-RV-087","article-title":"Progression of alcoholic and non-alcoholic steatohepatitis: common metabolic aspects of innate immune system and oxidative stress","volume":"26","author":"Sakaguchi","year":"2011","journal-title":"Drug Metab. Pharmacokinet."},{"key":"10.1016\/j.fct.2012.03.083_b0120","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.jep.2008.02.023","article-title":"Hepatoprotective effects of Ganoderma lucidum peptides against d-galactosamine-induced liver injury in mice","volume":"117","author":"Shi","year":"2008","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.fct.2012.03.083_b0125","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1056\/NEJM200011163432007","article-title":"Cytokines in alcoholic and nonalcoholic steatohepatitis","volume":"343","author":"Tilg","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.fct.2012.03.083_b0130","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0165-1110(88)90022-X","article-title":"Interaction of lipid peroxidation products with DNA","volume":"195","author":"Vaca","year":"1988","journal-title":"A Rev. Mutat. Res."},{"key":"10.1016\/j.fct.2012.03.083_b0135","first-page":"371","article-title":"Effects of a moderate dose of alcohol on blood lipids and lipoproteins postprandially and in the fasting state","volume":"25","author":"Veenstra","year":"1990","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.fct.2012.03.083_b0140","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jep.2009.08.028","article-title":"Evaluation of hepatoprotective effect of Zhi-Zi-Da-Huang decoction and its two fractions against acute alcohol-induced liver injury in rats","volume":"126","author":"Wang","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.fct.2012.03.083_b0145","series-title":"Global Status Report on Alcohol 2004","author":"WHO","year":"2004"},{"key":"10.1016\/j.fct.2012.03.083_b0150","first-page":"78","article-title":"Study on the preparation of corn functional oligopeptides and its SOD-like activity","volume":"23","author":"Xu","year":"2002","journal-title":"Chin. J. Biochem. Pharm."},{"key":"10.1016\/j.fct.2012.03.083_b0155","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1271\/bbb.61.1474","article-title":"The effects of corn peptide ingestion on facilitating alcohol metabolism in healthy men","volume":"61","author":"Yamaguchi","year":"1997","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.fct.2012.03.083_b0160","doi-asserted-by":"crossref","first-page":"7891","DOI":"10.1021\/jf0705670","article-title":"Peptide with angiotensin I-converting enzyme inhibitory activity from hydrolyzed corn gluten meal","volume":"55","author":"Yang","year":"2007","journal-title":"J. Agric. Food. Chem."},{"key":"10.1016\/j.fct.2012.03.083_b0165","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/ptr.2054","article-title":"Ginkgo biloba extract protects against alcohol-induced liver injury in rats","volume":"21","author":"Yuan","year":"2007","journal-title":"Phytother. Res."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691512002761?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691512002761?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T21:05:45Z","timestamp":1759525545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691512002761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0278691512002761"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2012.03.083","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Corn oligopeptides protect against early alcoholic liver injury in rats","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2012.03.083","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}