{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:35:22Z","timestamp":1791894922220,"version":"4.3.4"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.fct.2013.05.057","type":"journal-article","created":{"date-parts":[[2013,6,9]],"date-time":"2013-06-09T22:52:55Z","timestamp":1370818375000},"page":"129-136","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":359,"special_numbering":"C","title":["Glyphosate induces human breast cancer cells growth via estrogen receptors"],"prefix":"10.1016","volume":"59","author":[{"given":"Siriporn","family":"Thongprakaisang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apinya","family":"Thiantanawat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuchanart","family":"Rangkadilok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tawit","family":"Suriyo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jutamaad","family":"Satayavivad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2013.05.057_b0005","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1289\/ehp.6667","article-title":"Glyphosate biomonitoring for farmers and their families: results from the farm family exposure study","volume":"112","author":"Acquavella","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.fct.2013.05.057_b0010","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/ps.775","article-title":"Monitoring glyphosate residues in transgenic glyphosate resistant soybean","volume":"60","author":"Arregui","year":"2004","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.fct.2013.05.057_b0015","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.mam.2006.07.001","article-title":"Structure-function relationship of estrogen receptor alpha and beta: Impact on human health","volume":"27","author":"Ascenzi","year":"2006","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.fct.2013.05.057_b0020","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/s00244-006-0154-8","article-title":"Time- and dose-dependent effects of roundup on human embryonic and placental cells","volume":"53","author":"Benachour","year":"2007","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.fct.2013.05.057_b0025","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.fct.2003.08.003","article-title":"A generational study of glyphosate-tolerant soybeans on mouse fetal, postnatal, pubertal and adult testicular development","volume":"42","author":"Brake","year":"2004","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.fct.2013.05.057_b0030","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s000180300048","article-title":"Selective modulation of ER-beta by estradiol and xenoestrogens in human breast cancer cell lines","volume":"60","author":"Cappelletti","year":"2003","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.fct.2013.05.057_b0035","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s00204-006-0170-5","article-title":"Pre- and postnatal toxicity of the commercial glyphosate formulation in Wistar rats","volume":"81","author":"Dallegrave","year":"2007","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.fct.2013.05.057_b0040","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1006\/enrs.2000.4229","article-title":"Effect of the herbicide glyphosate on enzymatic activity in pregnant rats and their fetuses","volume":"85","author":"Daruich","year":"2001","journal-title":"Environ. Res."},{"key":"10.1016\/j.fct.2013.05.057_b0045","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.tox.2009.06.006","article-title":"Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines","volume":"262","author":"Gasnier","year":"2009","journal-title":"Toxicology"},{"key":"10.1016\/j.fct.2013.05.057_b0050","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1177\/0960327107083453","article-title":"Alteration of estrogen-regulated gene expression in human cells induced by the agricultural and horticultural herbicide glyphosate","volume":"26","author":"Hokanson","year":"2007","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.fct.2013.05.057_b0055","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/15298669191364334","article-title":"Occupational exposure of forest workers to glyphosate during brush saw spraying work","volume":"52","author":"Jauhiainena","year":"1991","journal-title":"Am. Ind. Hyg. Assoc. J."},{"key":"10.1016\/j.fct.2013.05.057_b0060","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/BF00213295","article-title":"Conifer seedling nursery worker exposure to glyphosate","volume":"22","author":"Lavy","year":"1992","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.fct.2013.05.057_b0065","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1080\/00984100050033494","article-title":"In vitro studies of cellular and molecular developmental toxicity of adjuvants, herbicides, and fungicides commonly used in Red River Valley, Minnesota","volume":"60","author":"Lin","year":"2000","journal-title":"J Toxicol Environ Health [Part A]"},{"key":"10.1016\/j.fct.2013.05.057_b0070","first-page":"98","article-title":"Biomonitoring for farm families in the farm family exposure study","volume":"31","author":"Mandel","year":"2005","journal-title":"Scan. J. Work Environ. Health"},{"key":"10.1016\/j.fct.2013.05.057_b0075","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.biolcel.2003.11.010","article-title":"Glyphosate-based pesticides affect cell cycle regulation","volume":"96","author":"Marc","year":"2004","journal-title":"Biol. Cell"},{"key":"10.1016\/j.fct.2013.05.057_b0080","first-page":"1155","article-title":"Non-Hodgkin\u2019s lymphoma and specific pesticide exposures in men","volume":"10","author":"McDuffie","year":"2001","journal-title":"Cancer Epidem. Biomar."},{"key":"10.1016\/j.fct.2013.05.057_b0085","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1038\/sj.bjc.6690479","article-title":"The two phyto-oestrogens genistein and quercetin exert different effects on oestrogen receptor function","volume":"80","author":"Miodini","year":"1999","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.fct.2013.05.057_b0090","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S1382-6689(99)00018-6","article-title":"Analysis of phyto-oestrogens by gas chromatography\u2013mass spectrometry","volume":"7","author":"Morton","year":"1999","journal-title":"Environ Toxicol. Phar."},{"key":"10.1016\/j.fct.2013.05.057_b0095","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1021\/jf981144o","article-title":"Isoflavones in retail and institutional soy foods","volume":"47","author":"Murphy","year":"1999","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.fct.2013.05.057_b0100","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1263\/jbb.100.685","article-title":"Analysis of isoflavone content in tempeh, a fermented soybean, and preparation of a new isoflavone-enriched tempeh","volume":"100","author":"Nakajima","year":"2005","journal-title":"J. Bioscience Bioeng."},{"key":"10.1016\/j.fct.2013.05.057_b0105","first-page":"2321","article-title":"Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines","volume":"56","author":"Pink","year":"1996","journal-title":"Cancer Res."},{"key":"10.1016\/j.fct.2013.05.057_b0110","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1159\/000226123","article-title":"Genistein in the presence of 17\u03b2-estradiol inhibits proliferation of ER\u03b2 breast cancer cells","volume":"84","author":"Rajah","year":"2009","journal-title":"Pharmacology"},{"key":"10.1016\/j.fct.2013.05.057_b0115","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1289\/ehp.7728","article-title":"Differential effects of glyphosate and Roundup on human placental cells and aromatase","volume":"113","author":"Richard","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.fct.2013.05.057_b0120","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.tips.2006.06.006","article-title":"The role of xenoestrogenic compounds in the development of breast cancer","volume":"27","author":"Safe","year":"2006","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.fct.2013.05.057_b0125","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s10549-006-9191-2","article-title":"Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha","volume":"99","author":"Seo","year":"2006","journal-title":"Breast Cancer Res. Tr."},{"key":"10.1016\/j.fct.2013.05.057_b0130","doi-asserted-by":"crossref","first-page":"758S","DOI":"10.1093\/jn\/129.3.758S","article-title":"Dietary isoflavones: biological effects and relevance to human health","volume":"129","author":"Setchell","year":"1999","journal-title":"J. Nutr."},{"key":"10.1016\/j.fct.2013.05.057_b0135","series-title":"Development of simple and sensitive HPLC method for determination of glyphosate residues in soybean. A thesis in Master of Science in Environmental Toxicology","author":"Sharma","year":"2009"},{"key":"10.1016\/j.fct.2013.05.057_b0140","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2741\/1010","article-title":"Xenoestrogen exposure and mechanisms of endocrine disruption","volume":"8","author":"Singleton","year":"2003","journal-title":"Front. Biosci."},{"key":"10.1016\/j.fct.2013.05.057_b0145","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/978-0-387-36903-7_2","article-title":"Coca and poppy eradication in Colombia: Environmental and human health assessment of aerially applied glyphosate","volume":"190","author":"Solomon","year":"2007","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"10.1016\/j.fct.2013.05.057_b0150","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/toxsci\/kfn141","article-title":"Influence of cellular ER\/ER ratio on the ER-agonist induced proliferation of human T47D breast cancer cells","volume":"105","author":"Sotoca","year":"2008","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.fct.2013.05.057_b0155","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/path.2130","article-title":"New perspectives into the biological and clinical relevance of oestrogen receptors in the human breast","volume":"211","author":"Speirs","year":"2007","journal-title":"J. Pathol."},{"key":"10.1016\/j.fct.2013.05.057_b0160","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1289\/ehp.00108769","article-title":"Roundup inhibits steroidogenesis by disrupting steroidogenic acute regulatory (StAR) protein expression","volume":"108","author":"Walsh","year":"2000","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.fct.2013.05.057_b0165","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1093\/carcin\/17.2.271","article-title":"Molecular effects of genistein on estrogen receptor mediated pathways","volume":"17","author":"Wang","year":"1996","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.fct.2013.05.057_b0170","unstructured":"WHO, 1994. Glyphosate. Environmental Health Criteria No. 159. World Health Organization, Geneva. <http:\/\/www.inchem.org\/documents\/ehc\/ehc\/ehc159.htm>."},{"key":"10.1016\/j.fct.2013.05.057_b0175","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/10937404.2012.632361","article-title":"Developmental and reproductive outcomes in humans and animals after glyphosate exposure: a critical analysis","volume":"15","author":"Williams","year":"2012","journal-title":"J. Toxicol. Environ. Health Part B"},{"key":"10.1016\/j.fct.2013.05.057_b0180","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/toxsci\/kfh180","article-title":"Development and characterization of a cell line that stably expresses an estrogen-responsive luciferase reporter for the detection of estrogen receptor agonist and antagonists","volume":"81","author":"Wilson","year":"2004","journal-title":"Toxicol. Sci."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691513003633?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691513003633?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T21:12:52Z","timestamp":1759525972000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691513003633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":36,"alternative-id":["S0278691513003633"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2013.05.057","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Glyphosate induces human breast cancer cells growth via estrogen receptors","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2013.05.057","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}