{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:24:18Z","timestamp":1790022258784,"version":"4.0.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.fct.2013.07.029","type":"journal-article","created":{"date-parts":[[2013,7,18]],"date-time":"2013-07-18T22:45:40Z","timestamp":1374187540000},"page":"123-129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Artocarpin attenuates ultraviolet B-induced skin damage in hairless mice by antioxidant and anti-inflammatory effect"],"prefix":"10.1016","volume":"60","author":[{"given":"Chiang-Wen","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horng-Huey","family":"Ko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Ching","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee-Yin","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Tzu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-Lin","family":"Yen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2013.07.029_b0005","first-page":"1200","article-title":"Polyphenols: skin photoprotection and inhibition of photocarcinogenes","volume":"11","author":"Afaq","year":"2011","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.fct.2013.07.029_b0010","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/j.1600-0625.2006.00466.x","article-title":"Botanical antioxidants in the prevention of photocarcinogenesis and photoaging","volume":"15","author":"Afaq","year":"2006","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.fct.2013.07.029_b0015","doi-asserted-by":"crossref","first-page":"423429","DOI":"10.1007\/s11418-010-0425-6","article-title":"Cytotoxic effect of artocarpin on T47D cells","volume":"64","author":"Arung","year":"2010","journal-title":"J. Nat. Med."},{"key":"10.1016\/j.fct.2013.07.029_b0020","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00403-008-0893-7","article-title":"TNF-alpha production in the skin","volume":"301","author":"Bashir","year":"2009","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.fct.2013.07.029_b0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0005-2760(95)00166-2","article-title":"Oxidative stress mediates synthesis of cytosolic phospholipase A2 after UVB injury","volume":"1299","author":"Chen","year":"1996","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.fct.2013.07.029_b0030","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.2174\/138161210791033923","article-title":"Signalling pathways activated by ultraviolet radiation: role in ocular and cutaneous health","volume":"16","author":"Di Girolamo","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.fct.2013.07.029_b0035","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1186\/1476-511X-10-235","article-title":"Whey protein enhances normal inflammatory responses during cutaneous wound healing in diabetic rats","volume":"10","author":"Ebaid","year":"2011","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.fct.2013.07.029_b0040","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3390\/nu2050482","article-title":"The relationship between ultraviolet radiation exposure and vitamin D status","volume":"2","author":"Engelsen","year":"2010","journal-title":"Nutrients"},{"key":"10.1016\/j.fct.2013.07.029_b0045","first-page":"385","article-title":"Chemopreventive effects of Calluna vulgaris and Vitis vinifera extracts on UVB-induced skin damage in SKH-1 hairless mice","volume":"62","author":"Filip","year":"2011","journal-title":"J. Physiol. Pharmacol."},{"key":"10.1016\/j.fct.2013.07.029_b0050","doi-asserted-by":"crossref","first-page":"570S","DOI":"10.1093\/ajcn\/88.2.570S","article-title":"Sun exposure and vitamin D sufficiency","volume":"88","author":"Gilchrest","year":"2008","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.fct.2013.07.029_b0055","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1089\/152308604322899369","article-title":"Role of lipid hydroperoxides in photo-oxidative stress signaling","volume":"6","author":"Girotti","year":"2004","journal-title":"Antioxid. Redox. Signal."},{"key":"10.1016\/j.fct.2013.07.029_b0060","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.mrfmmm.2004.09.013","article-title":"Inflammation, gene mutation and photoimmunosuppression in response to UVR-induced oxidative damage contributes to photocarcinogenesis","volume":"571","author":"Halliday","year":"2005","journal-title":"Mutat. Res."},{"key":"10.1016\/j.fct.2013.07.029_b0065","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2165\/00128071-200405010-00006","article-title":"Management of acute sunburn","volume":"5","author":"Han","year":"2004","journal-title":"Am. J. Clin. Dermatol."},{"key":"10.1016\/j.fct.2013.07.029_b0070","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1021\/np0600346","article-title":"Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production","volume":"69","author":"Han","year":"2006","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.fct.2013.07.029_b0075","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1046\/j.1365-2133.1999.02897.x","article-title":"Ultraviolet irradiation induces cyclooxygenase-2 expression in keratinocytes","volume":"140","author":"Isoherranen","year":"1999","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.fct.2013.07.029_b0080","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1080\/07315724.2004.10719356","article-title":"Protective effects of dietary soy isoflavones against UV-induced skin-aging in hairless mouse model","volume":"23","author":"Kim","year":"2004","journal-title":"J. Am. Coll. Nutr."},{"key":"10.1016\/j.fct.2013.07.029_b0085","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s10495-009-0324-z","article-title":"Cell death in the skin","volume":"14","author":"Lippens","year":"2009","journal-title":"Apoptosis"},{"key":"10.1016\/j.fct.2013.07.029_b0090","doi-asserted-by":"crossref","first-page":"S139","DOI":"10.1016\/j.jaad.2007.12.007","article-title":"Skin DNA photodamage and its biological consequences","volume":"58","author":"Marrot","year":"2008","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.fct.2013.07.029_b0095","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.taap.2003.08.019","article-title":"Toxic effects of ultraviolet radiation on the skin","volume":"195","author":"Matsumura","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.fct.2013.07.029_b0100","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.jaad.2011.07.011","article-title":"A review of targeted ultraviolet B phototherapy for psoriasis","volume":"66","author":"Mudigonda","year":"2012","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.fct.2013.07.029_b0105","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00403-009-0994-y","article-title":"The UV response of the skin: a review of the MAPK, NFkappaB and TNFalpha signal transduction pathways","volume":"302","author":"Muthusamy","year":"2010","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.fct.2013.07.029_b0110","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.fct.2013.07.029_b0115","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1600-0781.2011.00606.x","article-title":"Photo(chemo)therapy for vitiligo","volume":"27","author":"Pacifico","year":"2011","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"key":"10.1016\/j.fct.2013.07.029_b0120","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1467-2494.2004.00241.x","article-title":"Ultraviolet radiation and skin aging: roles of reactive oxygen species, inflammation and protease activation, and strategies for prevention of inflammation-induced matrix degradation \u2013 a review","volume":"27","author":"Pillai","year":"2005","journal-title":"Int. J. Cosmet. Sci."},{"key":"10.1016\/j.fct.2013.07.029_b0125","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1562\/0031-8655(2003)078<0068:IOTNFB>2.0.CO;2","article-title":"Induction of tumor necrosis factor-alpha by UVB: a role for reactive oxygen intermediates and eicosanoids","volume":"78","author":"Pupe","year":"2003","journal-title":"Photochem. Photobiol."},{"key":"10.1016\/j.fct.2013.07.029_b0130","doi-asserted-by":"crossref","first-page":"7389","DOI":"10.1021\/jf0400718","article-title":"Free radicals scavenging efficiency of a few naturally occurring flavonoids: a comparative study","volume":"52","author":"Rajendran","year":"2004","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.fct.2013.07.029_b0135","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/s11418-010-0427-4","article-title":"Prenylated flavones from Artocarpus altilis","volume":"64","author":"Shamaun","year":"2010","journal-title":"J. Nat. Med."},{"key":"10.1016\/j.fct.2013.07.029_b0140","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1055\/s-2000-11114","article-title":"The 5 alpha-reductase inhibitory components from heartwood of Artocarpus incisus: structure-activity investigations","volume":"66","author":"Shimizu","year":"2000","journal-title":"Planta Med."},{"key":"10.1016\/j.fct.2013.07.029_b0145","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1055\/s-2002-20057","article-title":"The skin-lightening effects of artocarpin on UVB-induced pigmentation","volume":"68","author":"Shimizu","year":"2002","journal-title":"Planta Med."},{"key":"10.1016\/j.fct.2013.07.029_b0150","doi-asserted-by":"crossref","first-page":"431","DOI":"10.2174\/138920010791526051","article-title":"Protecting skin photoaging by NF-kappaB inhibitor","volume":"11","author":"Tanaka","year":"2010","journal-title":"Curr. Drug Metab."},{"key":"10.1016\/j.fct.2013.07.029_b0155","doi-asserted-by":"crossref","first-page":"8969","DOI":"10.1021\/jf801345c","article-title":"Anthocyanins from black soybean seed coats inhibit UVB-induced inflammatory cylooxygenase-2 gene expression and PGE2 production through regulation of the nuclear factor-kappaB and phosphatidylinositol 3-kinase\/Akt pathway","volume":"56","author":"Tsoyi","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.fct.2013.07.029_b0160","doi-asserted-by":"crossref","first-page":"4292","DOI":"10.1016\/j.fct.2012.08.060","article-title":"Effects of Thai Musa species on prevention of UVB-induced skin damage in mice","volume":"50","author":"Viyoch","year":"2012","journal-title":"Food Chem. Toxicol."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691513004845?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691513004845?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T21:14:30Z","timestamp":1759526070000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691513004845"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":32,"alternative-id":["S0278691513004845"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2013.07.029","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Artocarpin attenuates ultraviolet B-induced skin damage in hairless mice by antioxidant and anti-inflammatory effect","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2013.07.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}