{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T02:37:49Z","timestamp":1778207869792,"version":"3.51.4"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.fct.2014.01.048","type":"journal-article","created":{"date-parts":[[2014,2,3]],"date-time":"2014-02-03T14:15:49Z","timestamp":1391436949000},"page":"254-261","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Species and gender differences in the carcinogenic activity of trimethylolpropane triacrylate in rats and mice"],"prefix":"10.1016","volume":"66","author":[{"given":"Inok","family":"Surh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepa B.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark F.","family":"Cesta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles D.","family":"H\u00e9bert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill F.","family":"Mann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Cunny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace E.","family":"Kissling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Malarkey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajendra S.","family":"Chhabra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2014.01.048_b0005","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1177\/0192623310391680","article-title":"Proceedings of the 2010 national toxicology program satellite symposium","volume":"39","author":"Adams","year":"2011","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.fct.2014.01.048_b0010","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1080\/15287398609530916","article-title":"Review of the toxicity of multifunctional acrylates","volume":"19","author":"Andrews","year":"1986","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.fct.2014.01.048_b0015","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1046\/j.1365-2559.1997.5460776.x","article-title":"Pathology of malignant mesothelioma","volume":"30","author":"Attanoos","year":"1997","journal-title":"Histopathology"},{"key":"10.1016\/j.fct.2014.01.048_b0020","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1177\/0192623309354111","article-title":"Proceedings of the 2009 national toxicology program satellite symposium","volume":"38","author":"Bach","year":"2010","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.fct.2014.01.048_b0025","doi-asserted-by":"crossref","first-page":"417","DOI":"10.2307\/2531856","article-title":"Effects of treatment-induced mortality and tumor-induced mortality on tests for carcinogenicity in small samples","volume":"44","author":"Bailer","year":"1988","journal-title":"Biometrics"},{"key":"10.1016\/j.fct.2014.01.048_b0030","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1600-0536.1994.tb02019.x","article-title":"The modulation of skin irritation","volume":"31","author":"Berardesca","year":"1994","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0035","doi-asserted-by":"crossref","first-page":"793","DOI":"10.2307\/2532200","article-title":"Ratio estimates, the delta method, and quantal response tests for increased carcinogenicity","volume":"49","author":"Bieler","year":"1993","journal-title":"Biometrics"},{"key":"10.1016\/j.fct.2014.01.048_b0040","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1600-0536.1984.tb00990.x","article-title":"The sensitizing capacity of multifunctional acrylates in the guinea pig","volume":"11","author":"Bjorkner","year":"1984","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0045","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1600-0536.1980.tb04983.x","article-title":"Allergic contact dermatitis from acrylates in ultraviolet curing inks","volume":"6","author":"Bjorkner","year":"1980","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0050","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/em.2850170408","article-title":"Genotoxicity of multifunctional acrylates in the salmonella\/mammalian-microsome assay and mouse lymphoma TK+\/\u2212assay","volume":"17","author":"Cameron","year":"1991","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.fct.2014.01.048_b0055","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/(SICI)1098-2744(199709)20:1<108::AID-MC12>3.0.CO;2-5","article-title":"Kinetics of wound-induced v-Ha-ras transgene expression and papilloma development in transgenic Tg.AC mice","volume":"20","author":"Cannon","year":"1997","journal-title":"Mol. Carcinogen."},{"key":"10.1016\/j.fct.2014.01.048_b0060","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3109\/01480548409042817","article-title":"Cross-reaction patterns in guinea pigs sensitized to acrylic monomers","volume":"7","author":"Clemmensen","year":"1984","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.fct.2014.01.048_b0065","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0378-4274(98)00323-3","article-title":"Cytokines and irritant contact dermatitis","volume":"102\u2013103","author":"Corsini","year":"1998","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.fct.2014.01.048_b0070","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1600-0536.1983.tb04317.x","article-title":"Contact allergy to trimethylolpropane triacrylate (TMPTA) in an aziridine plastic hardener","volume":"9","author":"Dahlquist","year":"1983","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0075","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1177\/0192623311431466","article-title":"Endometrial stromal polyps in rodents: biology, etiology, and relevance to disease in women","volume":"40","author":"Davis","year":"2012","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.fct.2014.01.048_b0080","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/mutage\/4.5.381","article-title":"Analysis of the genotoxicity of nine acrylate\/methacrylate compounds in L5178Y mouse lymphoma cells","volume":"4","author":"Dearfield","year":"1989","journal-title":"Mutagenesis"},{"key":"10.1016\/j.fct.2014.01.048_b0085","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1080\/01926230500295615","article-title":"Topical application of representative multifunctional acrylates produced proliferative and inflammatory lesions in F344\/N rats and B6C3F1 mice, and squamous cell neoplasms in Tg.AC mice","volume":"33","author":"Doi","year":"2005","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.fct.2014.01.048_b0220","series-title":"Pathology of the Fischer Rat Reference and Atlas","first-page":"63","article-title":"Peritoneum, retroperitoneum, mesentery, and abdominal cavity","author":"Hall","year":"1990"},{"key":"10.1016\/j.fct.2014.01.048_b0095","series-title":"Pathobiology of the Aging Mouse","first-page":"207","article-title":"Changes in the liver and gallbladder","author":"Harada","year":"1996"},{"key":"10.1016\/j.fct.2014.01.048_b0100","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1600-0536.1998.tb05755.x","article-title":"Airborne occupational allergic contact dermatitis due to trimethylolpropane triacrylate (TMPTA) used in the manufacture of printed circuit boards","volume":"38","author":"Kanerva","year":"1998","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0105","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.mrrev.2008.03.002","article-title":"Inflammation: gearing the journey to cancer","volume":"659","author":"Kundu","year":"2008","journal-title":"Mutat. Res."},{"key":"10.1016\/j.fct.2014.01.048_b0110","doi-asserted-by":"crossref","first-page":"9178","DOI":"10.1073\/pnas.87.23.9178","article-title":"V-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid","volume":"87","author":"Leder","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.fct.2014.01.048_b0115","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/j.1600-0536.2008.01449.x","article-title":"Occupational conjunctivitis as the sole manifestation of airborne contact allergy to trimethylolpropane triacrylate contained in a UV-cured paint","volume":"59","author":"Mancuso","year":"2008","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0120","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1080\/10408440902969430","article-title":"Induction of tunica vaginalis mesotheliomas in rats by xenobiotics","volume":"39","author":"Maronpot","year":"2009","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.fct.2014.01.048_b0125","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/j.1600-0536.1986.tb01285.x","article-title":"Allergic contact dermatitis from UV-curing acrylate in the manufacture of optical fibres","volume":"15","author":"Maurice","year":"1986","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0130","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1093\/oxfordjournals.aob.a087841","article-title":"Root graviresponsiveness and cellular differentiation in wild-type and a starchless mutant of Arabidopsis thaliana","volume":"64","author":"Moore","year":"1989","journal-title":"Ann. Bot."},{"key":"10.1016\/j.fct.2014.01.048_b0135","first-page":"109","article-title":"Health effects of selected chemicals 1. Trimethylpropane triacrylate","volume":"6","author":"Mortensen","year":"1992","journal-title":"Nord"},{"key":"10.1016\/j.fct.2014.01.048_b0210","first-page":"1","article-title":"Toxicology studies of trimethylolpropane triacrylate (technical grade) (CAS No. 15625-89-5) in F344\/N rats, B6C3F1 mice, and genetically modified (FVB Tg.AC hemizygous) mice (dermal studies)","author":"National Toxicology Program","year":"2005","journal-title":"Natl. Toxicol. Program Genet. Modif. Model Rep."},{"key":"10.1016\/j.fct.2014.01.048_b0145","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1365-2133.1978.tb01940.x","article-title":"Skin problems associated with multifunctional acrylic monomers in ultraviolet curing inks","volume":"98","author":"Nethercott","year":"1978","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.fct.2014.01.048_b0150","first-page":"241","article-title":"Allergic contact dermatitis due to urethane acrylate in ultraviolet cured inks","volume":"40","author":"Nethercott","year":"1983","journal-title":"Br. J. Ind. Med."},{"key":"10.1016\/j.fct.2014.01.048_b0155","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1600-0536.1983.tb04626.x","article-title":"Contact sensitivity to acrylate compounds in guinea pigs","volume":"9","author":"Parker","year":"1983","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.fct.2014.01.048_b0160","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/0272-0590(89)90004-3","article-title":"Testing for increased carcinogenicity using a survival-adjusted quantal response test","volume":"12","author":"Portier","year":"1989","journal-title":"Fundam. Appl. Toxicol.: Off. J. Soc. Toxicol."},{"key":"10.1016\/j.fct.2014.01.048_b0165","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1097\/AOG.0b013e3182a189ac","article-title":"Endometrial stromal sarcoma: a systematic review","volume":"122","author":"Rauh-Hain","year":"2013","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.fct.2014.01.048_b0170","doi-asserted-by":"crossref","first-page":"436","DOI":"10.3390\/cancers2020436","article-title":"Molecular mechanisms of mouse skin tumor promotion","volume":"2","author":"Rundhaug","year":"2010","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.fct.2014.01.048_b0175","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ejrad.2010.12.057","article-title":"Uterine sarcomas\u2013recent progress and future challenges","volume":"78","author":"Seddon","year":"2011","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.fct.2014.01.048_b0180","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/toxsci\/53.2.213","article-title":"Responses of transgenic mouse lines p53(+\/\u2212) and Tg.AC to agents tested in conventional carcinogenicity bioassays","volume":"53","author":"Spalding","year":"2000","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.fct.2014.01.048_b0185","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1177\/019262338801600302","article-title":"Spontaneous tumors in aging (C57BL\/6N x C3H\/HeN)F1 (B6C3F1) mice","volume":"16","author":"Tamano","year":"1988","journal-title":"Toxicol. Pathol."},{"issue":"Suppl","key":"10.1016\/j.fct.2014.01.048_b0215","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1080\/019262301753178474","article-title":"The Tg.AC (v-Ha-ras) transgenic mouse: nature of the model","volume":"29","author":"Tennant","year":"2001","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.fct.2014.01.048_b0195","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1080\/01926230290105802","article-title":"Hepatoblastomas in mice in the US national toxicology program (NTP) studies","volume":"30","author":"Turusov","year":"2002","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.fct.2014.01.048_b0200","unstructured":"United States Environmental Protection Agency, 2006. Non-confidential 2006 IUR records by chemical, including manufacturing, processing and use information."},{"key":"10.1016\/j.fct.2014.01.048_b0205","first-page":"1925","article-title":"Identification and control of contact dermatitis from polyfunctional acrylic monomers in five Swedish furniture companies","volume":"A27","author":"Voog","year":"1992","journal-title":"J. Environ. Sci. Health"}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691514000623?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691514000623?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T21:19:39Z","timestamp":1759526379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691514000623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":41,"alternative-id":["S0278691514000623"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2014.01.048","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Species and gender differences in the carcinogenic activity of trimethylolpropane triacrylate in rats and mice","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2014.01.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}