{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:59:14Z","timestamp":1791406754284,"version":"4.3.3"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100005416","name":"Norwegian Research Council","doi-asserted-by":"crossref","award":["213060"],"award-info":[{"award-number":["213060"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005416","name":"Norwegian Research Council","doi-asserted-by":"crossref","award":["185621"],"award-info":[{"award-number":["185621"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Norwegian Institute of Public Health"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.fct.2015.05.009","type":"journal-article","created":{"date-parts":[[2015,6,6]],"date-time":"2015-06-06T08:34:23Z","timestamp":1433579663000},"page":"17-25","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Early life exposure to bisphenol A investigated in mouse models of airway allergy, food allergy and oral tolerance"],"prefix":"10.1016","volume":"83","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2955-9970","authenticated-orcid":false,"given":"Unni Cecilie","family":"Nygaard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina Eriksen","family":"Vinje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari","family":"Samuelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Andreassen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Else-Carin","family":"Groeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette Kocbach","family":"B\u00f8lling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune","family":"Becher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martinus","family":"Lovik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Bodin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2015.05.009_bib1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1080\/15287394.2013.863746","article-title":"Particles influence allergic responses in mice\u2013role of gender and particle size","volume":"77","author":"Alberg","year":"2014","journal-title":"J.\u00a0Toxicol. Environ. Health A"},{"key":"10.1016\/j.fct.2015.05.009_bib2","doi-asserted-by":"crossref","first-page":"70","DOI":"10.2152\/jmi.53.70","article-title":"Altered allergic cytokine and antibody response in mice treated with bisphenol A","volume":"53","author":"Alizadeh","year":"2006","journal-title":"J.\u00a0Med. Investig. JMI"},{"issue":"1","key":"10.1016\/j.fct.2015.05.009_bib3","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1093\/toxsci\/kfs227","article-title":"The effects of maternal exposure to bisphenol a on allergic lung inflammation into adulthood","volume":"130","author":"Bauer","year":"2012","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.fct.2015.05.009_bib4","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1093\/toxsci\/kft242","article-title":"Transmaternal bisphenol A exposure accelerates diabetes type 1 development in NOD mice","volume":"137","author":"Bodin","year":"2014","journal-title":"Toxicol. Sci."},{"issue":"3","key":"10.1016\/j.fct.2015.05.009_bib5","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3109\/08923973.2013.772195","article-title":"Long-term bisphenol A exposure accelerates insulitis development in diabetes-prone NOD mice","volume":"35","author":"Bodin","year":"2013","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"10.1016\/j.fct.2015.05.009_bib6","doi-asserted-by":"crossref","first-page":"e79944","DOI":"10.1371\/journal.pone.0079944","article-title":"Disconcordance in statistical models of bisphenol A and chronic disease outcomes in NHANES 2003-08","volume":"8","author":"Casey","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.fct.2015.05.009_bib7","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1600-065X.2007.00509.x","article-title":"Mast cell tryptases and chymases in inflammation and host defense","volume":"217","author":"Caughey","year":"2007","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.fct.2015.05.009_bib8","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/bdrb.20170","article-title":"Early-life environment, developmental immunotoxicology, and the risk of pediatric allergic disease including asthma","volume":"83","author":"Dietert","year":"2008","journal-title":"Birth Defects Res. B Dev. Reprod. Toxicol."},{"key":"10.1016\/j.fct.2015.05.009_bib9","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1289\/ehp.1104052","article-title":"Endocrine disruptors and asthma-associated chemicals in consumer products","volume":"120","author":"Dodson","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.fct.2015.05.009_bib10","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.jaci.2012.12.1573","article-title":"Prenatal and postnatal bisphenol A exposure and asthma development among inner-city children","volume":"131","author":"Donohue","year":"2013","journal-title":"J.\u00a0Allergy Clin. Immunol."},{"key":"10.1016\/j.fct.2015.05.009_bib11","first-page":"75","article-title":"Opinion of the scientific panel on food additives, flavourings, processing aids and materials in contact with food on a request from the commission related to 2,2-bis(4-hydroxyphenyl) propane (bisphenol A)","volume":"428","author":"EFSA","year":"2006","journal-title":"EFSA J."},{"key":"10.1016\/j.fct.2015.05.009_bib12","first-page":"621","article-title":"Scientific opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs: PART II \u2013 toxicological assessment and risk characterisation","volume":"13","author":"EFSA","year":"2015","journal-title":"EFSA J."},{"key":"10.1016\/j.fct.2015.05.009_bib13","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.toxlet.2014.05.002","article-title":"Bisphenol A\u2013Why an adverse outcome pathway framework needs to be applied","volume":"230","author":"FitzGerald","year":"2014","journal-title":"Toxicol. Lett."},{"issue":"2","key":"10.1016\/j.fct.2015.05.009_bib14","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.jaci.2014.09.030","article-title":"Prenatal exposure to bisphenol A and phthalates and childhood respiratory tract infections and allergy","volume":"135","author":"Gascon","year":"2015","journal-title":"J.\u00a0Allergy Clin. Immunol."},{"key":"10.1016\/j.fct.2015.05.009_bib15","doi-asserted-by":"crossref","first-page":"3725","DOI":"10.1016\/j.fct.2012.07.059","article-title":"A\u00a0review of dietary and non-dietary exposure to bisphenol-A","volume":"50","author":"Geens","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.fct.2015.05.009_bib16","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1271\/bbb.70004","article-title":"Orally administered bisphenol A disturbed antigen specific immunoresponses in the naive condition","volume":"71","author":"Goto","year":"2007","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.fct.2015.05.009_bib17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0300-483X(00)00375-9","article-title":"IgE adjuvant effect caused by particles \u2013 immediate and delayed effects","volume":"156","author":"Granum","year":"2001","journal-title":"Toxicology"},{"key":"10.1016\/j.fct.2015.05.009_bib18","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/j.1365-3083.2011.02529.x","article-title":"Determinants of experimental allergic responses: interactions between allergen dose, sex and age","volume":"73","author":"Hansen","year":"2011","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.fct.2015.05.009_bib20","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.3390\/ijerph7072845","article-title":"Perinatal bisphenol A exposure in C57B6\/129svj male mice: potential altered cytokine\/chemokine production in adulthood","volume":"7","author":"Holladay","year":"2010","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.fct.2015.05.009_bib21","doi-asserted-by":"crossref","first-page":"e111383","DOI":"10.1371\/journal.pone.0111383","article-title":"Bisphenol a exposure and asthma development in school-age children: a longitudinal study","volume":"9","author":"Kim","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.fct.2015.05.009_bib22","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1046\/j.1365-2567.2003.01631.x","article-title":"Enhanced interleukin-4 production in CD4+ T cells and elevated immunoglobulin E levels in antigen-primed mice by bisphenol A and nonylphenol, endocrine disruptors: involvement of nuclear factor-AT and Ca2+","volume":"109","author":"Lee","year":"2003","journal-title":"Immunology"},{"key":"10.1016\/j.fct.2015.05.009_bib23","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1067\/mai.2000.107395","article-title":"A\u00a0murine model of peanut anaphylaxis: T- and B-cell responses to a major peanut allergen mimic human responses","volume":"106","author":"Li","year":"2000","journal-title":"J.\u00a0Allergy Clin. Immunol."},{"key":"10.1016\/j.fct.2015.05.009_bib24","doi-asserted-by":"crossref","first-page":"e112752","DOI":"10.1371\/journal.pone.0112752","article-title":"Perinatal exposure to a low dose of bisphenol a impaired systemic cellular immune response and predisposes young rats to intestinal parasitic infection","volume":"9","author":"Menard","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.fct.2015.05.009_bib25","doi-asserted-by":"crossref","first-page":"4893","DOI":"10.1096\/fj.14-255380","article-title":"Food intolerance at adulthood after perinatal exposure to the endocrine disruptor bisphenol A","volume":"28","author":"Menard","year":"2014","journal-title":"FASEB J."},{"key":"10.1016\/j.fct.2015.05.009_bib26","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1289\/ehp.0901259","article-title":"Maternal bisphenol a exposure promotes the development of experimental asthma in mouse pups","volume":"118","author":"Midoro-Horiuti","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.fct.2015.05.009_bib27","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1476-069X-11-8","article-title":"Fetal exposure to bisphenol A as a risk factor for the development of childhood asthma: an animal model study","volume":"11","author":"Nakajima","year":"2012","journal-title":"Environ. Health"},{"key":"10.1016\/j.fct.2015.05.009_bib28","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/toxsci\/kfp057","article-title":"Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice","volume":"109","author":"Nygaard","year":"2009","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.fct.2015.05.009_bib29","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/toxsci\/kfh287","article-title":"The capacity of particles to increase allergic sensitization is predicted by particle number and surface area, not by particle mass","volume":"82","author":"Nygaard","year":"2004","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"10.1016\/j.fct.2015.05.009_bib30","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1017\/S204017441400004X","article-title":"Perinatal bisphenol A exposure beginning before gestation enhances allergen sensitization, but not pulmonary inflammation, in adult mice","volume":"5","author":"O'Brien","year":"2014","journal-title":"J.\u00a0Dev. Orig. Health Dis."},{"key":"10.1016\/j.fct.2015.05.009_bib31","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3109\/1547691X.2013.822036","article-title":"Perinatal bisphenol A exposures increase production of pro-inflammatory mediators in bone marrow-derived mast cells of adult mice","volume":"11","author":"O'Brien","year":"2014","journal-title":"J.\u00a0Immunotoxicol."},{"key":"10.1016\/j.fct.2015.05.009_bib32","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1203\/PDR.0b013e3180674dae","article-title":"Transmaternal exposure to bisphenol a modulates the development of oral tolerance","volume":"62","author":"Ohshima","year":"2007","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.fct.2015.05.009_bib33","series-title":"WAO White Book on Allergy","author":"Pawankar","year":"2011"},{"key":"10.1016\/j.fct.2015.05.009_bib34","doi-asserted-by":"crossref","first-page":"e100468","DOI":"10.1371\/journal.pone.0100468","article-title":"Lifetime-dependent effects of bisphenol A on asthma development in an experimental mouse model","volume":"9","author":"Petzold","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.fct.2015.05.009_bib35","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.envint.2014.08.005","article-title":"Concentrations of phthalates and bisphenol A in Norwegian foods and beverages and estimated dietary exposure in adults","volume":"73","author":"Sakhi","year":"2014","journal-title":"Environ. Int."},{"key":"10.1016\/j.fct.2015.05.009_bib36","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1365-3083.2009.02244.x","article-title":"Particle size determines activation of the innate immune system in the lung","volume":"69","author":"Samuelsen","year":"2009","journal-title":"Scand. J Immunol."},{"key":"10.1016\/j.fct.2015.05.009_bib37","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.jaci.2013.11.020","article-title":"food allergy: epidemiology, pathogenesis, diagnosis, and treatment","volume":"133","author":"Sicherer","year":"2014","journal-title":"J.\u00a0Allergy Clin. Immunol."},{"issue":"6","key":"10.1016\/j.fct.2015.05.009_bib38","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1289\/ehp.1104175","article-title":"Prenatal exposure to bisphenol a and child wheeze from birth to three years","volume":"120","author":"Spanier","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.fct.2015.05.009_bib39","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1159\/000074305","article-title":"Bisphenol A promotes IL-4 production by Th2 cells","volume":"132","author":"Tian","year":"2003","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.fct.2015.05.009_bib40","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1080\/00365520600815639","article-title":"Murine model of food allergy after epicutaneous sensitization: role of mucosal mast cell protease-1","volume":"41","author":"Vaali","year":"2006","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.fct.2015.05.009_bib41","doi-asserted-by":"crossref","first-page":"800","DOI":"10.3109\/02770903.2012.721041","article-title":"Association of urinary bisphenol A concentration with allergic asthma: results from the national health and nutrition examination survey 2005-2006","volume":"49","author":"Vaidya","year":"2012","journal-title":"J.\u00a0Asthma"},{"key":"10.1016\/j.fct.2015.05.009_bib42","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1471-230X-9-33","article-title":"Food allergy alters jejunal circular muscle contractility and induces local inflammatory cytokine expression in a mouse model","volume":"9","author":"Valeur","year":"2009","journal-title":"BMC Gastroenterol."},{"key":"10.1016\/j.fct.2015.05.009_bib43","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1289\/ehp.0901716","article-title":"Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A","volume":"118","author":"Vandenberg","year":"2010","journal-title":"Environ. Health Perspect."},{"issue":"3","key":"10.1016\/j.fct.2015.05.009_bib44","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1210\/er.2011-1050","article-title":"Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses","volume":"33","author":"Vandenberg","year":"2012","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.fct.2015.05.009_bib45","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1111\/j.1365-2222.2009.03269.x","article-title":"A\u00a0mouse model of lupin allergy","volume":"39","author":"Vinje","year":"2009","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.fct.2015.05.009_bib46","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1046\/j.1365-2567.1997.00155.x","article-title":"Constitutive expression of mouse mast cell protease-1 in normal BALB\/c mice and its up-regulation during intestinal nematode infection","volume":"90","author":"Wastling","year":"1997","journal-title":"Immunology"},{"key":"10.1016\/j.fct.2015.05.009_bib47","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1038\/ajg.2013.92","article-title":"Mast cell tryptase reduces junctional adhesion molecule-A (JAM-A) expression in intestinal epithelial cells: implications for the mechanisms of barrier dysfunction in irritable bowel syndrome","volume":"108","author":"Wilcz-Villega","year":"2013","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.fct.2015.05.009_bib48","first-page":"365","article-title":"Effect of endocrine disrupters on immune responses in\u00a0vivo","volume":"25","author":"Yamashita","year":"2003","journal-title":"J.\u00a0UOEH"},{"key":"10.1016\/j.fct.2015.05.009_bib49","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1289\/ehp.10829","article-title":"Exposure to bisphenol a prenatally or in adulthood promotes T(H)2 cytokine production associated with reduction of CD4CD25 regulatory T cells","volume":"116","author":"Yan","year":"2008","journal-title":"Environ. Health Perspect."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027869151500174X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027869151500174X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T21:24:10Z","timestamp":1759526650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S027869151500174X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":48,"alternative-id":["S027869151500174X"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2015.05.009","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early life exposure to bisphenol A investigated in mouse models of airway allergy, food allergy and oral tolerance","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2015.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}