{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:37:50Z","timestamp":1792143470074,"version":"4.4.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.fct.2017.05.011","type":"journal-article","created":{"date-parts":[[2017,5,6]],"date-time":"2017-05-06T13:15:48Z","timestamp":1494076548000},"page":"1026-1031","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":58,"special_numbering":"P2","title":["Antiviral effect of compounds derived from Angelica archangelica L. on Herpes simplex virus-1 and Coxsackievirus B3 infections"],"prefix":"10.1016","volume":"109","author":[{"given":"Barbara","family":"Rajtar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9313-5929","authenticated-orcid":false,"given":"Krystyna","family":"Skalicka-Wo\u017aniak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0141ukasz","family":"\u015awi\u0105tek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Stec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastazja","family":"Boguszewska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u0142gorzata","family":"Polz-Dacewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2017.05.011_bib1","doi-asserted-by":"crossref","first-page":"7228","DOI":"10.1111\/j.1742-4658.2009.07402.x","article-title":"Viral entry mechanisms: cellular and viral mediators of Herpes simplex virus entry","volume":"276","author":"Akhtar","year":"2009","journal-title":"FEBS J."},{"key":"10.1016\/j.fct.2017.05.011_bib2","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/ptr.1629","article-title":"Naturally derived anti-HIV agents","volume":"19","author":"Asres","year":"2005","journal-title":"Phytother. Res."},{"key":"10.1016\/j.fct.2017.05.011_bib3","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/1743-422X-9-98","article-title":"Anti-herpes virus activities of bioactive fraction and isolated pure constituent of Mallotus peltatus: an ethnomedicine from Andaman Islands","volume":"9","author":"Bag","year":"2012","journal-title":"Virol. J."},{"key":"10.1016\/j.fct.2017.05.011_bib4","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/S0031-9422(97)89023-1","article-title":"Coumarins and anti-HBV constituents from Zanthoxylum schinifolium","volume":"45","author":"Chang","year":"1997","journal-title":"Phytochemistry"},{"key":"10.1016\/j.fct.2017.05.011_bib5","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.phrp.2016.11.003","article-title":"Evaluation of antiviral activity of Zanthoxylum species against picornaviruses","volume":"7","author":"Choi","year":"2016","journal-title":"Osong Public Health Res. Perspect"},{"key":"10.1016\/j.fct.2017.05.011_bib6","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.drudis.2016.03.003","article-title":"Novel therapeutic investigational strategies to treat severe and disseminated HSV infections suggested by a deeper understanding of in\u00a0vitro virus entry processes","volume":"21","author":"Clementi","year":"2016","journal-title":"Drug. Discov. Today"},{"key":"10.1016\/j.fct.2017.05.011_bib7","first-page":"523","article-title":"Anti-viral evaluation of sesquiterpene coumarins from Ferula assa-foetida against HSV-1. Iran J","volume":"13","author":"Ghannadi","year":"2014","journal-title":"Pharm. Res."},{"key":"10.1016\/j.fct.2017.05.011_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s12906-017-1562-1","article-title":"Antiviral effect of compounds derived from the seeds of Mammea americana and Tabernaemontana cymosa on Dengue and Chikungunya virus infections","volume":"17","author":"G\u00f3mez-Calder\u00f3n","year":"2017","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.fct.2017.05.011_bib9","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.ejmech.2016.07.056","article-title":"Therapeutic potential of coumarins as antiviral agents","volume":"123","author":"Hassan","year":"2016","journal-title":"Eur. J. M. Chem."},{"key":"10.1016\/j.fct.2017.05.011_bib10","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1111\/jphp.12436","article-title":"Bioactive natural products with anti-Herpes simplex virus properties","volume":"67","author":"Hassan","year":"2015","journal-title":"J.\u00a0Pharm. Pharmacol."},{"key":"10.1016\/j.fct.2017.05.011_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ijos.2016.3","article-title":"New strategies against drug resistance to Herpes simplex virus","volume":"8","author":"Jiang","year":"2016","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.fct.2017.05.011_bib12","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3390\/md202073","article-title":"Drugs and cosmetics from the sea","volume":"2","author":"Kijjoa","year":"2004","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.fct.2017.05.011_bib13","article-title":"Cinnamaldehyde derivatives inhibited Coxsackievirus B3-induced viral myocarditis","author":"Li","year":"2016","journal-title":"Biomol. Ther. Seoul."},{"key":"10.1016\/j.fct.2017.05.011_bib14","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.bmcl.2017.01.022","article-title":"Novel 12N-substituted matrinanes as potential anti-coxsackievirus agents","volume":"274","author":"Li","year":"2017","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.fct.2017.05.011_bib15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.4103\/2225-4110.124335","article-title":"Antiviral natural products and herbal medicines","volume":"4","author":"Lin","year":"2014","journal-title":"J.\u00a0Tradit. Complement. Med."},{"key":"10.1016\/j.fct.2017.05.011_bib16","doi-asserted-by":"crossref","first-page":"348","DOI":"10.3390\/molecules22030348","article-title":"Screening of six medicinal plant extracts obtained by two conventional methods and supercritical CO2 extraction targeted on coumarin content, 2,2-Diphenyl-1-picrylhydrazyl radical scavenging capacity and total phenols content","volume":"22","author":"Molnar","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.fct.2017.05.011_bib17","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0305-1978(03)00171-6","article-title":"Coumarins from the seeds of Angelica sylvestris and their distribution within the genus Angelica","volume":"32","author":"Murphy","year":"2004","journal-title":"Biochem. Syst. Ecol."},{"key":"10.1016\/j.fct.2017.05.011_bib18","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3923\/ijbc.2011.86.90","article-title":"Plant coumarins as allelopathic agents","volume":"5","author":"Razavi","year":"2011","journal-title":"Int. J. Biol. Chem."},{"key":"10.1016\/j.fct.2017.05.011_bib19","first-page":"493","article-title":"A\u00a0simple method of estimating fifty percent end points","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Hyg."},{"key":"10.1016\/j.fct.2017.05.011_bib20","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ejmech.2015.11.009","article-title":"Anti-herpetic and anti-dengue activity of abietane ferruginol analogues synthesized from (+)-dehydroabietylamine","volume":"108","author":"Roa-Linares","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.fct.2017.05.011_bib21","first-page":"361","article-title":"Synthesis and antiviral activity of 1-(1,3-disubstitutedimidazolidyn-2-ylidene)-3-ethoxycarbonylmethylurea derivatives","volume":"31","author":"Rz\u0105dkowska","year":"2016","journal-title":"J.\u00a0Enzyme. Inhib. Med. Chem."},{"key":"10.1016\/j.fct.2017.05.011_bib22","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.3390\/md8102619","article-title":"Antiviral lead compounds from marine sponges","volume":"8","author":"Sagar","year":"2010","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.fct.2017.05.011_bib23","doi-asserted-by":"crossref","first-page":"37349","DOI":"10.1074\/jbc.M401993200","article-title":"Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway","volume":"279","author":"Sancho","year":"2004","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.fct.2017.05.011_bib24","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.2174\/0929867043365189","article-title":"Natural medicine: the genus Angelica","volume":"11","author":"Sarker","year":"2004","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.fct.2017.05.011_bib25","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0196-9781(97)00377-X","article-title":"Amyloid beta-peptide-induced inhibition of MTT reduction in PC12h and C1300 neuroblastoma cells: effect of nitroprusside","volume":"19","author":"Takenouchi","year":"1998","journal-title":"Peptides"},{"key":"10.1016\/j.fct.2017.05.011_bib26","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.foodchem.2015.02.011","article-title":"Bioactivity-guided isolation of antimicrobial coumarins from Heracleum mantegazzianum Sommier & Levier (Apiaceae) fruits by high-performance counter-current chromatography","volume":"186","author":"Walasek","year":"2015","journal-title":"Food Chem."},{"key":"10.1016\/j.fct.2017.05.011_bib27","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.biopha.2016.12.117","article-title":"Inhibition viral RNP and anti-inflammatory activity of coumarins against influenza virus","volume":"87","author":"Wang","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.fct.2017.05.011_bib28","first-page":"57","article-title":"Interferon-mediated antiviral activities of Angelica tenuissima Nakai and its active components","volume":"54","author":"Weeratunga","year":"2016","journal-title":"J.\u00a0Microbiol."},{"key":"10.1016\/j.fct.2017.05.011_bib29","doi-asserted-by":"crossref","first-page":"6023","DOI":"10.3390\/molecules16076023","article-title":"Benzylidene-bis-(4-hydroxycoumarin) and benzopyrano-coumarin derivatives: synthesis, 1H\/13C-NMR conformational and X-ray crystal structure studies and in\u00a0vitro antiviral activity evaluations","volume":"16","author":"Zavr\u0161nik","year":"2011","journal-title":"Molecules"},{"key":"10.1016\/j.fct.2017.05.011_bib30","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.yexcr.2016.10.020","article-title":"Coxsackievirus B3 induces the formation of autophagosomes in cardiac fibroblasts both in\u00a0vitro and in\u00a0vivo","volume":"349","author":"Zhai","year":"2016","journal-title":"Exp. Cell. Res."},{"key":"10.1016\/j.fct.2017.05.011_bib31","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0031-9422(99)00554-3","article-title":"Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release","volume":"53","author":"Zhou","year":"2000","journal-title":"Phytochemistry"}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691517302399?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691517302399?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T22:56:25Z","timestamp":1535842585000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691517302399"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":31,"alternative-id":["S0278691517302399"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2017.05.011","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antiviral effect of compounds derived from Angelica archangelica L. on Herpes simplex virus-1 and Coxsackievirus B3 infections","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2017.05.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}