{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:53:29Z","timestamp":1790744009830,"version":"4.1.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.fct.2022.112979","type":"journal-article","created":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T12:06:12Z","timestamp":1649246772000},"page":"112979","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine"],"prefix":"10.1016","volume":"163","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6954-6309","authenticated-orcid":false,"given":"Muhammed Enes","family":"Inanc","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukru","family":"Gungor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz","family":"Yeni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatih","family":"Avdatek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5874-7797","authenticated-orcid":false,"given":"Volkan","family":"Ipek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruhi","family":"Turkmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3168-2510","authenticated-orcid":false,"given":"Orhan","family":"Corum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harun","family":"Karaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayhan","family":"Ata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2022.112979_bib1","series-title":"Identification of Essential Oils Components by Gas Chromatography\/Mass Spectroscopy","author":"Adams","year":"2007"},{"issue":"1","key":"10.1016\/j.fct.2022.112979_bib2","doi-asserted-by":"crossref","DOI":"10.1111\/and.12593","article-title":"Rutin ameliorates cisplatin-induced reproductive damage via suppression of oxidative stress and apoptosis in adult male rats","volume":"49","author":"Aksu","year":"2017","journal-title":"Andrologia"},{"key":"10.1016\/j.fct.2022.112979_bib3","first-page":"1","article-title":"Antidiarrhoeal principle of achyranthes ferruginea roxb. and their cytotoxicity","volume":"12","author":"Alam","year":"2002","journal-title":"Ban. Pharm. J."},{"key":"10.1016\/j.fct.2022.112979_bib4","first-page":"429","article-title":"The wealth of India, a dictionary of raw materials and industrial products, Raw materials","volume":"2950","author":"Anonymous","year":"2001","journal-title":"CSIR"},{"key":"10.1016\/j.fct.2022.112979_bib5","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.foodchem.2006.07.013","article-title":"Antioxidant properties of various solvent extracts of mulberry (morus indica l.) leaves","volume":"102","author":"Arabshahi-Delouee","year":"2007","journal-title":"Food Chem."},{"key":"10.1016\/j.fct.2022.112979_bib6","first-page":"77","article-title":"Effects of aqueous extract of eucalyptus globulus on lipid peroxidation and selected enzymes of rat liver","volume":"3","author":"Arise","year":"2009","journal-title":"J. Med. Plants Res."},{"key":"10.1016\/j.fct.2022.112979_bib7","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1600-079X.2006.00327.x","article-title":"Chemoprotective effect of melatonin against cisplatin-induced testicular toxicity in rats","volume":"41","author":"Atessahin","year":"2006","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.fct.2022.112979_bib8","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0015-0282(16)58109-6","article-title":"Protective effect of antioxidants on the impairment of sperm motility by activated polymorphonuclear leukocytes","volume":"65","author":"Baker","year":"1996","journal-title":"Fertil. Steril."},{"issue":"11","key":"10.1016\/j.fct.2022.112979_bib9","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1007\/BF02977371","article-title":"Anti-proliferate and pro-apoptotic effects of 2,3-dihydro-3,5- dihydroxy-6-methyl-4H-pyranone through Inactivation of NF-KB in human colon cancer cells","volume":"30","author":"Ban","year":"2007","journal-title":"Arch Pharm. Res. (Seoul)"},{"key":"10.1016\/j.fct.2022.112979_bib10","series-title":"Reproduction and Breeding Techniques for Laboratory Animals","author":"Bennett","year":"1970"},{"key":"10.1016\/j.fct.2022.112979_bib11","first-page":"882","article-title":"Improved method for the determination of blood glutathione","volume":"61","author":"Beutler","year":"1993","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.fct.2022.112979_bib12","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nrg2505","article-title":"The consequences of asynapsis for mammalian meiosis","volume":"10","author":"Burgoyne","year":"2009","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.fct.2022.112979_bib13","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1211\/0022357022313","article-title":"In-Vitro and invivo anti-inflammatory effect of oxyresveratrol from morus alba l","volume":"55","author":"Chung","year":"2003","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.fct.2022.112979_bib14","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/S0022-5347(17)49278-0","article-title":"Histological changes occurring in the contralateral testes of prepubertal rats subjected to various durations of unilateral spermatic cord torsion","volume":"133","author":"Cosentino","year":"1985","journal-title":"J. Urol."},{"key":"10.1016\/j.fct.2022.112979_bib15","series-title":"Fundamentals of Toxicologic Pathology","first-page":"459","article-title":"Male reproductive system","author":"Creasy","year":"2018"},{"issue":"2","key":"10.1016\/j.fct.2022.112979_bib16","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5923\/j.ajbe.20120202.03","article-title":"Diazinon affects the cytoarchitecture of seminiferous epithelium in rat testis","volume":"2","author":"Damodar","year":"2012","journal-title":"Am. J. Biomed. Eng."},{"key":"10.1016\/j.fct.2022.112979_bib17","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/S0031-9422(02)00753-7","article-title":"Antiviral flavonoids from the root bark of Morus Alba L","volume":"62","author":"Du","year":"2003","journal-title":"Phytochemistry"},{"key":"10.1016\/j.fct.2022.112979_bib18","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0027-5107(97)00153-X","article-title":"Induction of specific-locus and dominant lethal mutations in male mice by 1,3-bis_ 2-chloroethyl\/-1-nitrosourea _ BCNU\/and 1-_ 2-chloroethyl\/-3-cyclohexyl-1-nitrosourea _ CCNU\u2019","volume":"379","author":"Ehling","year":"1997","journal-title":"Mutat. Res."},{"key":"10.1016\/j.fct.2022.112979_bib19","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1016\/j.fct.2010.03.027","article-title":"Protective effect of N-acetylcysteine against carmustine-induced myelotoxicity in rats","volume":"48","author":"El-Sayed","year":"2010","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.fct.2022.112979_bib20","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/j.foodchem.2006.10.054","article-title":"Chemical composition of white (Morus alba), red (Morus rubra) and black (Morus nigra) mulberry fruits","volume":"103","author":"Ercisli","year":"2007","journal-title":"Food Chem."},{"key":"10.1016\/j.fct.2022.112979_bib21","doi-asserted-by":"crossref","first-page":"294","DOI":"10.2164\/jandrol.106.000935","article-title":"Sperm characteristics and DNA integrity of Iberian red deer (Cervus elaphus hispanicus) epididymal spermatozoa frozen in the presence of enzymatic and nonenzymatic antioxidants","volume":"28","author":"Fernandez-Santos","year":"2007","journal-title":"J. Androl."},{"key":"10.1016\/j.fct.2022.112979_bib22","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.anireprosci.2010.08.012","article-title":"Influence of sperm concentration on the motility, morphology, membrane and DNA integrity along with oxidative stress parameters of ram sperm during liquid storage","volume":"122","author":"Gundogan","year":"2010","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.fct.2022.112979_bib23","first-page":"1","article-title":"The Antioxidant role of mulberry (morus alba l) fruits in ameliorating the oxidative stress induced in \u03b3 -irradiated male rats","volume":"1","author":"Hamzaa","year":"2012","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.fct.2022.112979_bib24","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00204-008-0325-7","article-title":"Metallothionein attenuates carmustine-induced oxidative stress and protects against pulmonary wbrosis in rats","volume":"83","author":"Helal","year":"2009","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.fct.2022.112979_bib25","first-page":"127","article-title":"The effects of mulberry fruit on the antioxidative defense systems and oxidative stress in the erythrocytes of streptozotocin-induced diabetic rats","volume":"7","author":"Hong","year":"2004","journal-title":"J. Nutr. Sci."},{"key":"10.1016\/j.fct.2022.112979_bib26","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1095\/biolreprod61.2.393","article-title":"Role of radical oxygen species in rat testicular germ cell apoptosis induced by heat stress","volume":"61","author":"Ikeda","year":"1999","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.fct.2022.112979_bib27","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3390\/antiox8030072","article-title":"Measurement and clinical significance of lipid peroxidation as a biomarker of oxidative stress: oxidative stresss in diabetes, atherosclerosis, and chronic inflammation","volume":"8","author":"Ito","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.fct.2022.112979_bib28","first-page":"1780","article-title":"Immunoexpression of P63 and SOX2 in triple-negative breast cancers","volume":"6","author":"Kamarlis","year":"2017","journal-title":"Indonesia"},{"key":"10.1016\/j.fct.2022.112979_bib29","article-title":"Estimation of phenolic content, flavonoid content, antioxidant and alpha amylase inhibitory activity of marketed polyherbal formulation","volume":"4","author":"Kamtekar","year":"2014","journal-title":"J. Appl. Pharmaceut. Sci."},{"key":"10.1016\/j.fct.2022.112979_bib30","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1046\/j.1432-1033.2002.02809.x","article-title":"The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis","volume":"269","author":"Kaneko","year":"2002","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.fct.2022.112979_bib31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.foodchem.2005.03.019","article-title":"Antioxidant flavonol glycosides in mulberry (morus alba l.) leaves isolated based on LDL antioxidant activity","volume":"97","author":"Katsube","year":"2006","journal-title":"Food Chem."},{"key":"10.1016\/j.fct.2022.112979_bib32","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1095\/biolreprod59.4.890","article-title":"Rat epididymal sperm quantity, quality, and transit time after guanethidine-induced sympathectomy","volume":"59","author":"Kempinas","year":"1998","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.fct.2022.112979_bib33","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1756-0500-6-24","article-title":"A comparative study on the antioxidant activity of methanolic extracts from different parts of morus alba l. (Moraceae)","volume":"6","author":"Khan","year":"2013","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.fct.2022.112979_bib34","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1248\/cpb.58.568","article-title":"Albanol a from the root bark of morus alba l. induces apoptotic cell death in hl60 human leukemia cell line","volume":"58","author":"Kikuchi","year":"2010","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.fct.2022.112979_bib35","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1016\/j.freeradbiomed.2011.09.023","article-title":"Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors","volume":"51","author":"Kuo","year":"2011","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.fct.2022.112979_bib36","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1006\/bbrc.1995.1596","article-title":"Bioactivation of 5-hydroxymethyl-2-furaldehyde to an electrophilic and mutagenic allylic sulfuric aicd ester","volume":"3","author":"Lee","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.fct.2022.112979_bib37","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s12192-010-0238-2","article-title":"The protective role of 5-HMF against hypoxic injury","volume":"16","author":"Li","year":"2011","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.fct.2022.112979_bib38","first-page":"122","article-title":"Damaging effects of fourteen chemotherapeutic drugs on mouse testis cells","volume":"42","author":"Meistrich","year":"1982","journal-title":"Cancer Res."},{"key":"10.1016\/j.fct.2022.112979_bib39","series-title":"Human Chromosomes Forth Edition","author":"Miller","year":"2001"},{"key":"10.1016\/j.fct.2022.112979_bib40","series-title":"Third Scientific Conference - College of Veterinary Medicine - University of Tikrit","article-title":"Effects of Morus alba leaves extracts on sperm count and testicular weight in experimentally streptozotocin induced diabetes male rats","author":"Omar","year":"2016"},{"key":"10.1016\/j.fct.2022.112979_bib41","doi-asserted-by":"crossref","first-page":"889","DOI":"10.3390\/ijms19030889","article-title":"An interplay between senescence, apoptosis and autophagy in glioblastoma multiforme-role in pathogenesis and therapeutic perspective","volume":"19","author":"Pawlowska","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.fct.2022.112979_bib42","first-page":"37","article-title":"\u00c7ocukluk \u00e7a\u011f\u0131 kanser tedavisinin endokrin ge\u00e7 yan etkileri","volume":"25","author":"Poyrazoglu","year":"2010","journal-title":"T\u00fcrk Onkoloji Dergisi."},{"issue":"7","key":"10.1016\/j.fct.2022.112979_bib43","first-page":"191","article-title":"Screening of antioxidant activity, total phenolics and GC-MS study of Vitex negundo","volume":"4","author":"Praveen Kumar","year":"2010","journal-title":"Afr. J. Biochem. Res."},{"key":"10.1016\/j.fct.2022.112979_bib44","doi-asserted-by":"crossref","first-page":"92","DOI":"10.2174\/1871520611009010092","article-title":"Male fertility-implications of anticancer treatment and strategies to mitigate gonadotoxicity","volume":"10","author":"Ragheb","year":"2010","journal-title":"Anti Cancer Agents Med. Chem."},{"key":"10.1016\/j.fct.2022.112979_bib45","first-page":"969","article-title":"Quinacrine enhances carmustine therapy of experimental rat glioma","volume":"49","author":"Reyes","year":"2001","journal-title":"Neurosurgery"},{"key":"10.1016\/j.fct.2022.112979_bib46","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1080\/10715760701261533","article-title":"Peroxyl radical trapping activity of anthocyanins and generation of free radical intermediates","volume":"41","author":"Rossetto","year":"2007","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.fct.2022.112979_bib47","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.urology.2008.08.474","article-title":"Male fertility after cancer","volume":"73","author":"Sabanegh","year":"2009","journal-title":"Urology"},{"key":"10.1016\/j.fct.2022.112979_bib48","first-page":"137","article-title":"Chemotherapy, free radicals and oxidative stress","volume":"31","author":"Sabuncuoglu","year":"2011","journal-title":"Hacettepe Univ. J. Fac. Pharm."},{"key":"10.1016\/j.fct.2022.112979_bib49","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1016\/j.biopha.2017.09.057","article-title":"Gilaburu (Viburnum opulus L.) fruit extract alleviates testis and sperm damages induced by taxane-based chemotherapeutics","volume":"95","author":"Sariozkan","year":"2017","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.fct.2022.112979_bib50","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0378-4320(00)00073-7","article-title":"The use of transmigration and spermac\u00ae stain to evaluate epididymal cat spermatozoa","volume":"59","author":"Schafer","year":"2000","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.fct.2022.112979_bib51","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1517\/14712598.5.4.477","article-title":"Local derivery of antinoplastic agents by controlled-release polymers for the treatment of malignant brain tumors","volume":"5","author":"Shan","year":"2005","journal-title":"Opin. Biol. Ther."},{"key":"10.1016\/j.fct.2022.112979_bib52","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0090-4295(96)00313-5","article-title":"Role of reactive oxygen species in male infertility","volume":"48","author":"Sharma","year":"1996","journal-title":"Urology"},{"key":"10.1016\/j.fct.2022.112979_bib53","article-title":"Protective effects of cerebrolysin against chemotherapy (carmustine) induced cognitive impairment in Albino mice","author":"Sharma","year":"2021","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.fct.2022.112979_bib54","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jocn.2021.01.037","article-title":"Long-term follow-up after BCNU wafer implantation in patients with newly diagnosed glioblastoma","volume":"86","author":"Shibahara","year":"2021","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.fct.2022.112979_bib55","doi-asserted-by":"crossref","first-page":"6196","DOI":"10.1166\/jnn.2021.18596","article-title":"Effect of superparamagnetic DMSO@y-Fe2O3 combined with carmustine on cervical cancer","volume":"21","author":"Shu","year":"2021","journal-title":"J. Nanosci. Nanotechnol."},{"key":"10.1016\/j.fct.2022.112979_bib56","first-page":"78","article-title":"Oxidative stress and role of antioxidants in normal and abnormal sperm function","volume":"1","author":"Sikka","year":"1996","journal-title":"Front. Bio. Sci."},{"key":"10.1016\/j.fct.2022.112979_bib57","first-page":"83","article-title":"Approaches to industrial exploitation of mulberry (mulberry sp.) fruits","volume":"18","author":"Singhal","year":"2010","journal-title":"J. Fruit Ornam. Plant Res."},{"key":"10.1016\/j.fct.2022.112979_bib58","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/B978-0-7020-4088-7.00080-8","article-title":"Neurologic complications of chemotherapy and other newer and experimental approaches","volume":"121","author":"Soffietti","year":"2014","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.fct.2022.112979_bib59","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1016\/j.theriogenology.2004.10.003","article-title":"The effect of ascorbic acid supplementation on sperm quality, lipid peroxidation and testosterone levels of male wistar rats","volume":"63","author":"Sonmez","year":"2005","journal-title":"Theriogenology"},{"key":"10.1016\/j.fct.2022.112979_bib60","series-title":"Erkek \u00dcreme Organlar\u0131n\u0131n Muayenesi; Reprod\u00fcktif anatomi,Edit\u00f6r: Ala\u00e7am","author":"Tekin","year":"1990"},{"key":"10.1016\/j.fct.2022.112979_bib61","first-page":"115","article-title":"Protective effect of mulberry leaf extract on male rat fertility affected with methotrexate-cytotoxicity","volume":"6","author":"Tolba","year":"2014","journal-title":"Egypt. Acad.J. Biol. Sci."},{"key":"10.1016\/j.fct.2022.112979_bib62","first-page":"73","article-title":"Adverse effects of chemotherapeutics on male reproductive system and protective strategies","volume":"17","author":"Turk","year":"2013","journal-title":"Marmara Pharm. J."},{"key":"10.1016\/j.fct.2022.112979_bib63","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.fertnstert.2007.04.059","article-title":"Improvement of cisplatin-induced injuries to sperm quality, the oxidant-antioxidant system, and the histologic structure of the rat testis by ellagic acid","volume":"89","author":"Turk","year":"2008","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.fct.2022.112979_bib64","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1439-0272.2009.00917.x","article-title":"Human sperm DNA integrity in normal and abnormal semen samples and its correlation with sperm characteristics","volume":"41","author":"Varghese","year":"2009","journal-title":"Andrologia"},{"key":"10.1016\/j.fct.2022.112979_bib65","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1055\/s-0030-1250599","article-title":"Mulberroside a possesses potent uricosuric and nephroprotective effects in hyperuricemic mice","volume":"77","author":"Wang","year":"2011","journal-title":"Planta Med."},{"key":"10.1016\/j.fct.2022.112979_bib66","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1742-7843.2005.pto960112.x","article-title":"Screening of antioxidants from medicinal plants for cardioprotective effect against doxorubicin toxicity","volume":"96","author":"Wattanapitayakul","year":"2005","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"key":"10.1016\/j.fct.2022.112979_bib67","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1631\/jzus.2007.B0439","article-title":"Investigation on influencing factors of 5-HMF content in Schisandra","volume":"8","author":"Xu","year":"2007","journal-title":"J. Zhejiang Univ. - Sci."},{"key":"10.1016\/j.fct.2022.112979_bib68","doi-asserted-by":"crossref","first-page":"10604","DOI":"10.1021\/jf403098y","article-title":"In vitro antioxidant and antiproliferative activities of 5-Hydroxymethylfurfural","volume":"61","author":"Zhao","year":"2013","journal-title":"J. Agric. Food Chem."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691522001776?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691522001776?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T22:19:03Z","timestamp":1759529943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691522001776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":68,"alternative-id":["S0278691522001776"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2022.112979","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2022.112979","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112979"}}