{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T18:33:22Z","timestamp":1791657202211,"version":"4.3.4"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100010166","name":"Xiamen City Department of Science and Technology","doi-asserted-by":"publisher","award":["3502Z20222004"],"award-info":[{"award-number":["3502Z20222004"]}],"id":[{"id":"10.13039\/100010166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005045","name":"Ministry of Finance of the People's Republic of China","doi-asserted-by":"publisher","award":["2060302"],"award-info":[{"award-number":["2060302"]}],"id":[{"id":"10.13039\/501100005045","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.fct.2023.114155","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T22:06:22Z","timestamp":1698444382000},"page":"114155","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Icariin induces developmental toxicity via thyroid hormone disruption in zebrafish larvae"],"prefix":"10.1016","volume":"182","author":[{"given":"Meifang","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naying","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxiao","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenghong","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.fct.2023.114155_bib1","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1002\/ptr.6893","article-title":"Potential roles of medicinal plants for the treatment of viral diseases focusing on COVID-19: a review","volume":"35","author":"Adhikari","year":"2021","journal-title":"Phytother Res."},{"key":"10.1016\/j.fct.2023.114155_bib2","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.jsps.2019.05.005","article-title":"A study of the role of DIO1 and DIO2 polymorphism in thyroid cancer and drug response to therapy in the Saudi population","volume":"27","author":"AlRasheed","year":"2019","journal-title":"Saudi Pharmaceut. J."},{"issue":"3","key":"10.1016\/j.fct.2023.114155_bib3","doi-asserted-by":"crossref","first-page":"R59","DOI":"10.1530\/EC-19-0543","article-title":"Impact of hyperthyroidism on cardiac hypertrophy","volume":"9","author":"Barreto-Chaves","year":"2020","journal-title":"Endocr. Connect."},{"issue":"1","key":"10.1016\/j.fct.2023.114155_bib4","first-page":"32","article-title":"Anticancer drug-induced thyroid dysfunction","volume":"16","author":"Bhattacharya","year":"2020","journal-title":"Eur. Endocrinol."},{"key":"10.1016\/j.fct.2023.114155_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3389\/fendo.2017.00163","article-title":"Thyroid allostasis-adaptive responses of thyrotropic feedback control to conditions of strain, stress, and developmental programming","volume":"8","author":"Chatzitomaris","year":"2017","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.fct.2023.114155_bib6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.aquatox.2012.01.008","article-title":"Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae","volume":"110","author":"Chen","year":"2012","journal-title":"Aquat. Toxicol."},{"issue":"1","key":"10.1016\/j.fct.2023.114155_bib7","article-title":"Fish toxicity testing for identification of thyroid disrupting chemicals","volume":"284","author":"Dang","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.fct.2023.114155_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2021.100988","article-title":"Perinatal effects of persistent organic pollutants on thyroid hormone concentration in placenta and breastmilk","volume":"87","author":"De Angelis","year":"2022","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.fct.2023.114155_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2021.112158","article-title":"Plant constituents and thyroid: a revision of the main phytochemicals that interfere with thyroid function","volume":"152","author":"Di Dalmazi","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.fct.2023.114155_bib10","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1089\/105072501300176363","article-title":"Update on intrathyroidal iodine metabolism","volume":"11","author":"Dunn","year":"2001","journal-title":"Thyroid"},{"key":"10.1016\/j.fct.2023.114155_bib11","first-page":"1e10","article-title":"The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety","volume":"177","author":"Ekor","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.fct.2023.114155_bib12","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1177\/1535370216643418","article-title":"Cardioprotective effects of sitagliptin against doxorubicin induced cardiotoxicity in rats","volume":"241","author":"El-Agamy","year":"2016","journal-title":"Exp. Biol. Med."},{"issue":"1","key":"10.1016\/j.fct.2023.114155_bib13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/nrendo.2014.186","article-title":"Thyroid transcription factors in development, differentiation and disease","volume":"11","author":"Fern\u00e1ndez","year":"2015","journal-title":"Nat. Rev. Endocrinol."},{"issue":"9","key":"10.1016\/j.fct.2023.114155_bib14","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/s41573-021-00233-1","article-title":"Targeting oxidative stress in disease: promise and limitations of antioxidant therapy","volume":"20","author":"Forman","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.fct.2023.114155_bib15","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.aquatox.2017.10.024","article-title":"Thyroid disrupting effects of halogenated and next generation chemicals on the swim bladder development of zebrafish","volume":"193","author":"Godfrey","year":"2017","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.fct.2023.114155_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113228","article-title":"Deep eutectic solvent combined with ultrasound-assisted extraction as high efficient extractive media for extraction and quality evaluation of Herba epimedii","volume":"185","author":"Guo","year":"2020","journal-title":"J. Pharmaceut. Biomed."},{"issue":"18","key":"10.1016\/j.fct.2023.114155_bib17","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1002\/jssc.200700262","article-title":"Simultaneous determination of nine flavonoids and qualitative evaluation of Herba epimedii by high performance liquid chromatography with ultraviolet detection","volume":"30","author":"Huang","year":"2007","journal-title":"J. Separ. Sci."},{"key":"10.1016\/j.fct.2023.114155_bib18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.aquatox.2010.02.003","article-title":"Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS)","volume":"98","author":"Huang","year":"2010","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.fct.2023.114155_bib19","first-page":"204","article-title":"Phytochemistry and ethnopharmacology of epimedium L. Species","volume":"7","author":"Jiang","year":"2015","journal-title":"Chin. Herb. Med."},{"key":"10.1016\/j.fct.2023.114155_bib20","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.bcp.2009.11.006","article-title":"Endocrine disruptors and thyroid hormone physiology","volume":"79","author":"Jugan","year":"2010","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.fct.2023.114155_bib21","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.ygcen.2007.09.005","article-title":"Characterization of thyroid hormones and thyroid hormone receptors during the early development of Pacific bluefin tuna (Thunnus orientalis)","volume":"155","author":"Kawakami","year":"2008","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.fct.2023.114155_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2021.105813","article-title":"Zebrafish as the toxicant screening model: transgenic and omics approaches","volume":"234","author":"Lai","year":"2021","journal-title":"Aquat. Toxicol."},{"issue":"8","key":"10.1016\/j.fct.2023.114155_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070172","article-title":"Inter-individual and inter-strain variations in zebrafish locomotor ontogeny","volume":"8","author":"Lange","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.fct.2023.114155_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127037","article-title":"Fluxapyroxad induces developmental delay in zebrafish (Danio rerio)","volume":"256","author":"Li","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.fct.2023.114155_bib25","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1126\/science.aad8828","article-title":"Environmentally relevant concentrations of microplastic particles influence larval fish ecology","volume":"352","author":"L\u00f6nnstedt","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.fct.2023.114155_bib26","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.freeradbiomed.2022.06.009","article-title":"New mechanism of nephrotoxicity of triptolide: oxidative stress promotes cGAS-STING signaling pathway[J]","volume":"188","author":"Lu","year":"2022","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.fct.2023.114155_bib27","first-page":"327","article-title":"Amiodarone and thyroid dysfunction","volume":"61","author":"Medi\u0107","year":"2022","journal-title":"Acta Clin. Croat."},{"key":"10.1016\/j.fct.2023.114155_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2019.104521","article-title":"The role of amiodarone in contemporary management of complex cardiac arrhythmias","volume":"151","author":"Mujovi\u0107","year":"2020","journal-title":"Pharmacol. Res."},{"issue":"3","key":"10.1016\/j.fct.2023.114155_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/1559325820959563","article-title":"Therapeutic response of epimedium gandiflorum's different doses to restore the antioxidant potential and reproductive hormones in male albino rats","volume":"18","author":"Munir","year":"2020","journal-title":"Dose Response"},{"issue":"11","key":"10.1016\/j.fct.2023.114155_bib30","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3389\/fphar.2020.00256","article-title":"Icariin ameliorates diabetic cardiomyopathy through Apelin\/Sirt3 signalling to improve mitochondrial dysfunction","volume":"19","author":"Ni","year":"2020","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.fct.2023.114155_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0099-5428(08)60529-8","article-title":"Analytical profile of amiodarone","volume":"20","author":"Plomp","year":"1991","journal-title":"Anal. Profiles Drug Subst."},{"key":"10.1016\/j.fct.2023.114155_bib32","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.mce.2009.05.011","article-title":"Thyroid gland development and function in the zebrafish model","volume":"312","author":"Porazzi","year":"2009","journal-title":"Mol. Cell. Endocrinol."},{"issue":"11","key":"10.1016\/j.fct.2023.114155_bib33","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1002\/jmor.10558","article-title":"Development of the swimbladder and its innervation in the zebrafish, Danio rerio","volume":"268","author":"Robertson","year":"2010","journal-title":"J. Morphol."},{"key":"10.1016\/j.fct.2023.114155_bib34","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.mrgentox.2017.07.002","article-title":"Developmental toxicity and DNA damaging properties of silver nanoparticles in the catfish (Clarias gariepinus)","volume":"822","author":"Sayed","year":"2017","journal-title":"Mutat. Res-Gen. Tox. En."},{"issue":"5","key":"10.1016\/j.fct.2023.114155_bib35","first-page":"517","article-title":"Icariin ameliorates oxidative stress-induced inflammation, apoptosis, and heart failure in isoproterenol-challenged Wistar rats","volume":"26","author":"Sharma","year":"2023","journal-title":"Iran. J. Basic Med. Sci."},{"key":"10.1016\/j.fct.2023.114155_bib36","article-title":"Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part II: zebrafish","volume":"204\u2013217","author":"Stinckens","year":"2016","journal-title":"Aquat. Toxicol."},{"issue":"1","key":"10.1016\/j.fct.2023.114155_bib37","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1080\/13880209.2020.1859552","article-title":"Oxidative stress-mediated hepatotoxicity in rats induced by ethanol extracts of different parts of Chloranthus serratus","volume":"58","author":"Sun","year":"2020","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.fct.2023.114155_bib38","doi-asserted-by":"crossref","first-page":"H2181","DOI":"10.1152\/ajpheart.00554.2011","article-title":"Oxidative stress and heart failure","volume":"301","author":"Tsutsui","year":"2011","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.fct.2023.114155_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2022.109335","article-title":"Exposure to diclofenac alters thyroid hormone levels and transcription of genes involved in the hypothalamic-pituitary-thyroid axis in zebrafish embryos\/larvae","volume":"257","author":"Wang","year":"2022","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.fct.2023.114155_bib40","article-title":"Perfluoropolyether carboxylic acids (novel alternatives to PFOA) impair zebrafish posterior swim bladder development via thyroid hormone disruption","volume":"134","author":"Wang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.fct.2023.114155_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114565","article-title":"The toxic effect of bisphenol AF and nanoplastic coexposure in parental and offspring generation zebrafish","volume":"251","author":"Wang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.fct.2023.114155_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113334","article-title":"Developmental toxicity of bromoacetamide via the thyroid hormone receptors-mediated disruption of thyroid hormone homeostasis in zebrafish embryos","volume":"233","author":"Wang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.fct.2023.114155_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2019.105280","article-title":"Comparative thyroid disruption by o,p'-DDT and p,p'-DDE in zebrafish embryos\/larvae","volume":"216","author":"Wu","year":"2019","journal-title":"Aquat. Toxicol."},{"issue":"8","key":"10.1016\/j.fct.2023.114155_bib44","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1007\/s10646-013-1107-4","article-title":"Effects of low-level hexabromocyclododecane (HBCD) exposure on cardiac development in zebrafish embryos","volume":"22","author":"Wu","year":"2013","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.fct.2023.114155_bib45","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.scitotenv.2019.04.323","article-title":"Long-term exposure to the non-steroidal anti-inflammatory drug (NSAID) naproxen causes thyroid disruption in zebrafish at environmentally relevant concentrations","volume":"676","author":"Xu","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.fct.2023.114155_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2022.113438","article-title":"Lucidenic acid A inhibits the binding of hACE2 receptor with spike protein to prevent SARS-CoV-2 invasion","volume":"169","author":"Xu","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.fct.2023.114155_bib47","article-title":"Review article mechanism of action of icariin in bone marrow mesenchymal stem cells","volume":"5747298","author":"Yang","year":"2019","journal-title":"Stem Cell. Int."},{"key":"10.1016\/j.fct.2023.114155_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111641","article-title":"The agrochemical s-metolachlor disrupts molecular mediators and morphology of the swim bladder: implications for locomotor activity in zebrafish (Danio rerio)","volume":"208","author":"Yang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.fct.2023.114155_bib49","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jep.2017.02.033","article-title":"Effects of the combined Herba epimedii and Fructus Ligustri Lucidi on bone turnover and TGF-\u03b21\/Smads pathway in GIOP rats","volume":"201","author":"Yang","year":"2017","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.fct.2023.114155_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.112642","article-title":"Icariin and its metabolites as potential protective phytochemicals against cardiovascular disease: from effects to molecular mechanisms","volume":"147","author":"Zeng","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.fct.2023.114155_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2022.106180","article-title":"Cadmium impairs zebrafish swim bladder development via ROS mediated inhibition of the Wnt\/Hedgehog pathway","volume":"247","author":"Zhang","year":"2022","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.fct.2023.114155_bib52","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2020.571598","article-title":"Selective estrogen receptor modulator-like activities of Herba epimedii extract and its interactions with tamoxifen and raloxifene in bone cells and tissues","volume":"11","author":"Zhou","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.fct.2023.114155_bib53","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.lfs.2016.01.013","article-title":"Evidence that diclofenac and celecoxib are thyroid hormone receptor beta antagonists","volume":"146","author":"Zloh","year":"2016","journal-title":"Life Sci."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691523005574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691523005574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T19:27:48Z","timestamp":1762284468000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691523005574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":53,"alternative-id":["S0278691523005574"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2023.114155","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Icariin induces developmental toxicity via thyroid hormone disruption in zebrafish larvae","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2023.114155","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114155"}}