{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:54:33Z","timestamp":1785887673041,"version":"3.56.0"},"reference-count":145,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation","doi-asserted-by":"publisher","award":["HEA_FF_68_155_3700_013"],"award-info":[{"award-number":["HEA_FF_68_155_3700_013"]}],"id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.fct.2026.116163","type":"journal-article","created":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T15:25:49Z","timestamp":1778945149000},"page":"116163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Chemotherapy-induced peripheral neuropathy: Mechanisms of toxicity and potential natural compounds-based therapeutics"],"prefix":"10.1016","volume":"215","author":[{"given":"Kishore K.","family":"Kumaree","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatin N.","family":"Mohd Jaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijack","family":"Fong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tewin","family":"Tencomnao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2074-8262","authenticated-orcid":false,"given":"James M.","family":"Brimson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8884-3077","authenticated-orcid":false,"given":"Anchalee","family":"Prasansuklab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib1","first-page":"126","article-title":"Effect of Matricaria chamomilla hydroalcoholic extract on cisplatin-induced neuropathy in mice","volume":"9","author":"Abad","year":"2011","journal-title":"Chin. J. Nat. Med."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib2","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1080\/15569527.2021.1940195","article-title":"Protection against experimental cisplatin-induced optic nerve toxicity using resveratrol: a rat model study","volume":"40","author":"Agcayazi","year":"2021","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.fct.2026.116163_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2020.172972","article-title":"6-Methoxyflavanone abates cisplatin-induced neuropathic pain apropos anti-inflammatory mechanisms: a behavioral and molecular simulation study","volume":"872","author":"Akbar","year":"2020","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.fct.2026.116163_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1295096","article-title":"An aqueous commiphora myrrha extract ameliorates paclitaxel-induced peripheral neuropathic pain in mice","volume":"14","author":"Al-Romaiyan","year":"2023","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s13181-012-0239-x","article-title":"The effect of curcumin on oxaliplatin and cisplatin neurotoxicity in rats: some behavioral, biochemical, and histopathological studies","volume":"9","author":"Al Moundhri","year":"2013","journal-title":"J. Med. Toxicol."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib6","article-title":"Interventions for preventing neuropathy caused by cisplatin and related compounds","volume":"2014","author":"Albers","year":"2014","journal-title":"Cochrane Database Syst. Rev."},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib7","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1089\/acm.2010.0716","article-title":"Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers","volume":"17","author":"Allen","year":"2011","journal-title":"J. Alternative Compl. Med."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib8","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1186\/s12906-017-1976-9","article-title":"Neuro-protective effect of rutin against Cisplatin-induced neurotoxic rat model","volume":"17","author":"Almutairi","year":"2017","journal-title":"BMC Compl. Alternative Med."},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib9","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1248\/bpb.b16-00899","article-title":"Prophylactic administration of Aucubin inhibits paclitaxel-induced mechanical allodynia via the inhibition of endoplasmic reticulum stress in peripheral schwann cells","volume":"40","author":"Andoh","year":"2017","journal-title":"Biol. Pharm. Bull."},{"issue":"23","key":"10.1016\/j.fct.2026.116163_bib10","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1056\/NEJMoa032709","article-title":"Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer","volume":"350","author":"Andr\u00e9","year":"2004","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24043885","article-title":"Natural products and neuroprotection 3.0","volume":"24","author":"Angeloni","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib12","doi-asserted-by":"crossref","first-page":"7463","DOI":"10.1007\/s12035-018-0920-4","article-title":"Rosmarinic acid mitigates mitochondrial dysfunction and spinal glial activation in oxaliplatin-induced peripheral neuropathy","volume":"55","author":"Areti","year":"2018","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.fct.2026.116163_bib13","doi-asserted-by":"crossref","DOI":"10.1177\/1744806917714693","article-title":"Ion channels and neuronal hyperexcitability in chemotherapy-induced peripheral neuropathy: cause and effect?","volume":"13","author":"Aromolaran","year":"2017","journal-title":"Mol. Pain"},{"key":"10.1016\/j.fct.2026.116163_bib14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/1744-8069-9-53","article-title":"The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplatin-induced chronic painful peripheral neuropathy","volume":"9","author":"Azevedo","year":"2013","journal-title":"Mol. Pain"},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib15","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1515\/BC.2009.033","article-title":"Glutathione dysregulation and the etiology and progression of human diseases","volume":"390","author":"Ballatori","year":"2009","journal-title":"Biol. Chem."},{"key":"10.1016\/j.fct.2026.116163_bib16","doi-asserted-by":"crossref","first-page":"401","DOI":"10.12788\/jcso.0086","article-title":"Chemotherapy-induced peripheral neuropathy and impact on quality of life 6 months after treatment with chemotherapy","volume":"12","author":"Beijers","year":"2014","journal-title":"J. Community Support Oncol."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib17","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/j.pain.0000000000001385","article-title":"Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury\u2013associated peripheral sensory neuropathy via block of N-and T-type calcium channels","volume":"160","author":"Bellampalli","year":"2019","journal-title":"Pain"},{"key":"10.1016\/j.fct.2026.116163_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114511","article-title":"Effectiveness of crocin of saffron (Crocus sativus L.) against chemotherapy-induced peripheral neuropathy: a randomized, double-blind, placebo-controlled clinical trial","volume":"281","author":"Bozorgi","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib19","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3109\/10408441003601836","article-title":"The relationship between cisplatin-induced reactive oxygen species, glutathione, and BCL-2 and resistance to cisplatin","volume":"40","author":"Brozovic","year":"2010","journal-title":"Crit. Rev. Toxicol."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib20","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1021\/acschemneuro.8b00617","article-title":"(\u2212)-Hardwickiic acid and Hautriwaic acid induce Antinociception via blockade of Tetrodotoxin-sensitive voltage-dependent sodium channels","volume":"10","author":"Cai","year":"2018","journal-title":"ACS Chem. Neurosci."},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib21","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3390\/toxics3020198","article-title":"Mitochondrial dysfunction in chemotherapy-induced peripheral neuropathy (CIPN)","volume":"3","author":"Canta","year":"2015","journal-title":"Toxics"},{"issue":"16","key":"10.1016\/j.fct.2026.116163_bib22","doi-asserted-by":"crossref","first-page":"3478","DOI":"10.1200\/JCO.2002.07.061","article-title":"Neuroprotective effect of reduced glutathione on oxaliplatin-based chemotherapy in advanced colorectal cancer: a randomized, double-blind, placebo-controlled trial","volume":"20","author":"Cascinu","year":"2002","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.fct.2026.116163_bib23","series-title":"Alkaloids: a Suitable Precursor for Nanomaterials Synthesis, and their Various Applications Secondary Metabolites Based Green Synthesis of Nanomaterials and their Applications","first-page":"23","author":"Chaachouay","year":"2023"},{"key":"10.1016\/j.fct.2026.116163_bib24","article-title":"Vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: a meta-analysis","volume":"12","author":"Chen","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"5","key":"10.1016\/j.fct.2026.116163_bib25","first-page":"3140","article-title":"Tanshinone IIA ameliorates oxaliplatin-induced neurotoxicity via mitochondrial protection and autophagy promotion","volume":"11","author":"Cheng","year":"2019","journal-title":"Am. J. Transl. Res."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib26","doi-asserted-by":"crossref","first-page":"304","DOI":"10.3390\/toxics3030304","article-title":"Current view in platinum drug mechanisms of peripheral neurotoxicity","volume":"3","author":"Chiorazzi","year":"2015","journal-title":"Toxics"},{"key":"10.1016\/j.fct.2026.116163_bib27","first-page":"1","article-title":"Aqueous extract of lithospermi radix attenuates oxaliplatin-induced neurotoxicity in both in vitro and in vivo models","volume":"16","author":"Cho","year":"2016","journal-title":"BMC Compl. Alternative Med."},{"issue":"5\u20136","key":"10.1016\/j.fct.2026.116163_bib28","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1515\/znc-2016-0194","article-title":"Effects of Hypericum perforatum extract on oxaliplatin-induced neurotoxicity: in vitro evaluations","volume":"72","author":"Cinci","year":"2017","journal-title":"Z. Naturforsch., C: J. Biosci."},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib29","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s41110-023-00231-w","article-title":"Omega-3 fatty acids as adjuvant therapy in the adverse effects of antineoplastic treatment for breast cancer: a systematic review","volume":"48","author":"Delmicon","year":"2023","journal-title":"Nutrire"},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3892\/etm.2022.11523","article-title":"Resveratrol ameliorates oxaliplatin-induced neuropathic pain via anti-inflammatory effects in rats","volume":"24","author":"Dong","year":"2022","journal-title":"Exp. Ther. Med."},{"issue":"6048","key":"10.1016\/j.fct.2026.116163_bib31","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1126\/science.1206243","article-title":"HCN2 ion channels play a central role in inflammatory and neuropathic pain","volume":"333","author":"Emery","year":"2011","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/eurjhf\/hfq213","article-title":"Cardiovascular side effects of cancer therapies: a position statement from the heart failure association of the European society of cardiology","volume":"13","author":"Eschenhagen","year":"2011","journal-title":"Eur. J. Heart Fail."},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib33","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/10408360500523878","article-title":"Glutathione in cancer biology and therapy","volume":"43","author":"Estrela","year":"2006","journal-title":"Crit. Rev. Clin. Lab Sci."},{"key":"10.1016\/j.fct.2026.116163_bib34","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/bs.pmbts.2014.12.002","article-title":"Chemotherapy-induced peripheral neuropathy","volume":"131","author":"Fehrenbacher","year":"2015","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib35","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1002\/mnfr.201300455","article-title":"Grape seed proanthocyanidin extract improves the hepatic glutathione metabolism in obese Z ucker rats","volume":"58","author":"Fern\u00e1ndez\u2010Iglesias","year":"2014","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.fct.2026.116163_bib36","first-page":"1347","volume":"vol. 27","author":"Ferreira","year":"2022"},{"key":"10.1016\/j.fct.2026.116163_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.102925","article-title":"Cisplatin: the first metal based anticancer drug","volume":"88","author":"Ghosh","year":"2019","journal-title":"Bioorg. Chem."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib38","doi-asserted-by":"crossref","first-page":"92","DOI":"10.4103\/2277-9175.156656","article-title":"Pistachio supplementation attenuates motor and cognition impairments induced by cisplatin or vincristine in rats","volume":"4","author":"Golchin","year":"2015","journal-title":"Adv. Biomed. Res."},{"issue":"31","key":"10.1016\/j.fct.2026.116163_bib39","doi-asserted-by":"crossref","first-page":"5319","DOI":"10.2174\/092986712803833335","article-title":"Terpene compounds in nature: a review of their potential antioxidant activity","volume":"19","author":"Gonzalez-Burgos","year":"2012","journal-title":"Curr. Med. Chem."},{"issue":"Suppl. 4","key":"10.1016\/j.fct.2026.116163_bib40","first-page":"iv45","article-title":"Peripheral neuropathies from chemotherapeutics and targeted agents: diagnosis, treatment, and prevention","volume":"14","author":"Grisold","year":"2012","journal-title":"Neuro Oncol."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib41","first-page":"544","article-title":"Reduced glutathione protects against cisplatin-induced neurotoxicity in rats","volume":"53","author":"Hamers","year":"1993","journal-title":"Cancer Res."},{"issue":"5","key":"10.1016\/j.fct.2026.116163_bib42","doi-asserted-by":"crossref","first-page":"755","DOI":"10.3390\/ph16050755","article-title":"Resveratrol enhances cytotoxic effects of cisplatin by inducing cell cycle arrest and apoptosis in ovarian adenocarcinoma SKOV-3 cells through activating the p38 MAPK and suppressing AKT","volume":"16","author":"Hankittichai","year":"2023","journal-title":"Pharmaceuticals"},{"issue":"12","key":"10.1016\/j.fct.2026.116163_bib43","doi-asserted-by":"crossref","first-page":"3620","DOI":"10.1245\/s10434-007-9556-8","article-title":"Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells","volume":"14","author":"Hering","year":"2007","journal-title":"Ann. Surg Oncol."},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib44","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1039\/c3mt20251h","article-title":"In vitro studies on cisplatin focusing on kinetic aspects of intracellular chemistry by LC-ICP-MS","volume":"5","author":"Hermann","year":"2013","journal-title":"Metallomics"},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib45","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1089\/acm.2020.0012","article-title":"Topical Costus sp. preparation as palliative care for chemotherapy-induced peripheral neuropathy of patients: a randomized placebo-controlled pilot trial","volume":"26","author":"Heydarirad","year":"2020","journal-title":"J. Alternative Compl. Med."},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib46","first-page":"571","article-title":"Treatment of chemotherapy-induced peripheral neuropathy: systematic review and recommendations","volume":"21","author":"Hou","year":"2018","journal-title":"Pain Physician"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib47","doi-asserted-by":"crossref","first-page":"3928","DOI":"10.1038\/s41598-017-04283-7","article-title":"Alpha-lipoic acid suppresses P2X receptor activities and visceral hypersensitivity to colorectal distention in diabetic rats","volume":"7","author":"Hu","year":"2017","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib48","doi-asserted-by":"crossref","first-page":"237","DOI":"10.5114\/wo.2016.61567","article-title":"Vitamin E does not decrease the incidence of chemotherapy-induced peripheral neuropathy: a meta-analysis","volume":"20","author":"Huang","year":"2016","journal-title":"Contemporary Oncology\/Wsp\u00f3\u0142czesna Onkologia"},{"key":"10.1016\/j.fct.2026.116163_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtemb.2021.126798","article-title":"Role of ferroptosis in cisplatin-induced acute nephrotoxicity in mice","volume":"67","author":"Ikeda","year":"2021","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"5","key":"10.1016\/j.fct.2026.116163_bib50","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1097\/j.pain.0000000000002454","article-title":"Dorsal root ganglion toll-like receptor 4 signaling contributes to oxaliplatin-induced peripheral neuropathy","volume":"163","author":"Illias","year":"2022","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib51","doi-asserted-by":"crossref","first-page":"5947","DOI":"10.1038\/s41598-017-05784-1","article-title":"Taxanes and platinum derivatives impair Schwann cells via distinct mechanisms","volume":"7","author":"Imai","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fct.2026.116163_bib52","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.fct.2014.07.022","article-title":"Protective effect of polydatin, a natural precursor of resveratrol, against cisplatin-induced toxicity in rats","volume":"72","author":"Ince","year":"2014","journal-title":"Food Chem. Toxicol."},{"issue":"11","key":"10.1016\/j.fct.2026.116163_bib53","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/S0891-5849(00)00410-X","article-title":"Lipoic acid decreases lipid peroxidation and protein glycosylation and increases (Na++ K+)-and Ca++-ATPase activities in high glucose-treated human erythrocytes","volume":"29","author":"Jain","year":"2000","journal-title":"Free Radic. Biol. Med."},{"issue":"12","key":"10.1016\/j.fct.2026.116163_bib54","doi-asserted-by":"crossref","first-page":"6918","DOI":"10.1002\/ptr.7304","article-title":"Neuroprotective properties of ethanolic extract of citrus unshiu Markovich peel through NADPH oxidase 2 inhibition in chemotherapy\u2010induced neuropathic pain animal model","volume":"35","author":"Jang","year":"2021","journal-title":"Phytother Res."},{"key":"10.1016\/j.fct.2026.116163_bib55","doi-asserted-by":"crossref","first-page":"5879","DOI":"10.2147\/IJGM.S329257","article-title":"An update in our understanding of the relationships between gene polymorphisms and chemotherapy-induced nausea and vomiting","author":"Jin","year":"2021","journal-title":"Int. J. Gen. Med."},{"issue":"5","key":"10.1016\/j.fct.2026.116163_bib56","doi-asserted-by":"crossref","first-page":"3436","DOI":"10.1021\/acs.chemrev.5b00597","article-title":"The next generation of platinum drugs: targeted Pt (II) agents, nanoparticle delivery, and Pt (IV) prodrugs","volume":"116","author":"Johnstone","year":"2016","journal-title":"Chem. Rev."},{"issue":"21","key":"10.1016\/j.fct.2026.116163_bib57","doi-asserted-by":"crossref","first-page":"12234","DOI":"10.1021\/ic400538c","article-title":"Monofunctional and higher-valent platinum anticancer agents","volume":"52","author":"Johnstone","year":"2013","journal-title":"Inorg. Chem."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib58","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s12906-017-1556-z","article-title":"Anti-allodynic effect of Buja in a rat model of oxaliplatin-induced peripheral neuropathy via spinal astrocytes and pro-inflammatory cytokines suppression","volume":"17","author":"Jung","year":"2017","journal-title":"BMC Compl. Alternative Med."},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib59","doi-asserted-by":"crossref","first-page":"329","DOI":"10.5306\/wjco.v8.i4.329","article-title":"Platinum-induced neurotoxicity: a review of possible mechanisms","volume":"8","author":"Kanat","year":"2017","journal-title":"World J. Clin. Oncol."},{"key":"10.1016\/j.fct.2026.116163_bib60","article-title":"Exploring chemotherapy-induced peripheral neuropathy management practice patterns among oncology clinicians","volume":"vol. 40","author":"Kanzawa-Lee","year":"2024"},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib61","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1595\/147106710X534326","article-title":"Michele peyrone (1813\u20101883), discoverer of cisplatin","volume":"54","author":"Kauffman","year":"2010","journal-title":"Platin. Met. Rev."},{"issue":"8","key":"10.1016\/j.fct.2026.116163_bib62","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrc2167","article-title":"The resurgence of platinum-based cancer chemotherapy","volume":"7","author":"Kelland","year":"2007","journal-title":"Nat. Rev. Cancer"},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib63","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106485","article-title":"Role of the DNA base excision repair protein, APE1 in cisplatin, oxaliplatin, or carboplatin induced sensory neuropathy","volume":"9","author":"Kelley","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib64","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1080\/01480545.2018.1504058","article-title":"Effect of curcumin nanoparticles on the cisplatin-induced neurotoxicity in rat","volume":"42","author":"Khadrawy","year":"2019","journal-title":"Drug Chem. Toxicol."},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib65","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.3390\/molecules21091253","article-title":"The suppressive effects of cinnamomi cortex and its phytocompound coumarin on oxaliplatin-induced neuropathic cold allodynia in rats","volume":"21","author":"Kim","year":"2016","journal-title":"Molecules"},{"issue":"11","key":"10.1016\/j.fct.2026.116163_bib66","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1523\/JNEUROSCI.6054-09.2010","article-title":"Roles of NADPH oxidases in cisplatin-induced reactive oxygen species generation and ototoxicity","volume":"30","author":"Kim","year":"2010","journal-title":"J. Neurosci."},{"issue":"3\u20134","key":"10.1016\/j.fct.2026.116163_bib67","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1159\/000503259","article-title":"Antiallodynic effect of intrathecal Korean red ginseng in cisplatin-induced neuropathic pain rats","volume":"105","author":"Kim","year":"2020","journal-title":"Pharmacology"},{"issue":"11","key":"10.1016\/j.fct.2026.116163_bib68","first-page":"1769","article-title":"The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase III clinical trial","volume":"19","author":"Kottschade","year":"2011","journal-title":"Support. Care Cancer"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib69","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/mus.20340","article-title":"Oxaliplatin-induced neurotoxicity and the development of neuropathy","volume":"32","author":"Krishnan","year":"2005","journal-title":"Muscle Nerve"},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib70","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.4103\/1673-5374.276321","article-title":"Insights into platinum-induced peripheral neuropathy\u2013current perspective","volume":"15","author":"Lazi\u0107","year":"2020","journal-title":"Neural Regen. Res."},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib71","doi-asserted-by":"crossref","DOI":"10.1002\/prp2.819","article-title":"Analgesic effects of medicinal plants and phytochemicals on chemotherapy\u2010induced neuropathic pain through glial modulation","volume":"9","author":"Lee","year":"2021","journal-title":"Pharmacol. Res. Perspect."},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib72","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines8090324","article-title":"The role of satellite glial cells, astrocytes, and microglia in oxaliplatin-induced neuropathic pain","volume":"8","author":"Lee","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.fct.2026.116163_bib73","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/1472-6882-12-124","article-title":"Effect of green tea extracts on oxaliplatin-induced peripheral neuropathy in rats","volume":"12","author":"Lee","year":"2012","journal-title":"BMC Compl. Alternative Med."},{"issue":"5","key":"10.1016\/j.fct.2026.116163_bib74","doi-asserted-by":"crossref","first-page":"139","DOI":"10.21010\/ajtcam.v13i5.18","article-title":"Anti-nociceptive effect of Agrimonia eupatoria extract on a cisplatin-induced neuropathic model","volume":"13","author":"Lee","year":"2016","journal-title":"Afr. J. Tradit., Complementary Altern. Med."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib75","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1749-8546-5-20","article-title":"Pharmacology of ginsenosides: a literature review","volume":"5","author":"Leung","year":"2010","journal-title":"Chin. Med."},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib76","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.1039\/D1FO04391A","article-title":"Protective effect of food derived nutrients on cisplatin nephrotoxicity and its mechanism","volume":"13","author":"Liu","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.fct.2026.116163_bib77","article-title":"Regulation mechanism of curcumin mediated inflammatory pathway and its clinical application: a review","volume":"16","author":"Liu","year":"2025","journal-title":"Front. Pharmacol."},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib78","doi-asserted-by":"crossref","first-page":"474","DOI":"10.5483\/BMBRep.2018.51.9.114","article-title":"Resveratrol enhances cisplatin-induced apoptosis in human hepatoma cells via glutamine metabolism inhibition","volume":"51","author":"Liu","year":"2018","journal-title":"BMB Rep."},{"issue":"28","key":"10.1016\/j.fct.2026.116163_bib79","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1200\/JCO.20.01399","article-title":"Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO guideline update","volume":"38","author":"Loprinzi","year":"2020","journal-title":"J. Clin. Oncol."},{"issue":"14","key":"10.1016\/j.fct.2026.116163_bib80","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.2174\/1381612824666180410091511","article-title":"Cytochrome P450s and alcoholic liver disease","volume":"24","author":"Lu","year":"2018","journal-title":"Curr. Pharm. Des."},{"issue":"11","key":"10.1016\/j.fct.2026.116163_bib81","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1002\/cncr.31248","article-title":"Beyond symptomatic relief for chemotherapy-induced peripheral neuropathy: targeting the source","volume":"124","author":"Ma","year":"2018","journal-title":"Cancer"},{"issue":"8","key":"10.1016\/j.fct.2026.116163_bib82","first-page":"4223","article-title":"Chemotherapy-induced peripheral neuropathy (CIPN): current therapies and topical treatment option with high-concentration capsaicin","volume":"29","author":"Maih\u00f6fner","year":"2021","journal-title":"Support. Care Cancer"},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib83","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.jpain.2011.11.009","article-title":"Oxaliplatin-induced neuropathy: oxidative stress as pathological mechanism. Protective effect of silibinin","volume":"13","author":"Mannelli","year":"2012","journal-title":"J. Pain"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib84","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1158\/1535-7163.MCT-08-0840","article-title":"Platinum neurotoxicity pharmacogenetics","volume":"8","author":"McWhinney","year":"2009","journal-title":"Mol. Cancer Therapeut."},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib85","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.expneurol.2008.08.013","article-title":"Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy","volume":"214","author":"Melli","year":"2008","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.fct.2026.116163_bib86","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.neuro.2012.09.011","article-title":"Curcumin reduces cisplatin-induced neurotoxicity in NGF-differentiated PC12 cells","volume":"34","author":"Mendonca","year":"2013","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.fct.2026.116163_bib87","article-title":"Berberine alleviate cisplatin-induced peripheral neuropathy by modulating inflammation signal via TRPV1","volume":"12","author":"Meng","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib88","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-32691-w","article-title":"Effect of Vitis vinifera hydroalcoholic extract against oxaliplatin neurotoxicity: in vitro and in vivo evidence","volume":"8","author":"Micheli","year":"2018","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib89","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1007\/s12325-025-03173-z","article-title":"Co-treatment with gabapentinoid and Japanese herbal medicine goshajinkigan for CIPN is associated with longer duration and higher dose of chemotherapy","volume":"42","author":"Miyano","year":"2025","journal-title":"Adv. Ther."},{"key":"10.1016\/j.fct.2026.116163_bib90","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2019.172472","article-title":"Alkaloids for cancer prevention and therapy: current progress and future perspectives","volume":"858","author":"Mondal","year":"2019","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib91","first-page":"246","article-title":"n-3 polyunsaturated fatty acids: the potential role for supplementation in cancer","volume":"15","author":"Murphy","year":"2012","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib92","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s43094-020-00161-8","article-title":"Flavonoids as natural phenolic compounds and their role in therapeutics: an overview","volume":"7","author":"Mutha","year":"2021","journal-title":"Future J. Pharmaceut. Sci."},{"key":"10.1016\/j.fct.2026.116163_bib93","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2020.112963","article-title":"Neoline, an active ingredient of the processed aconite root in Goshajinkigan formulation, targets Nav1. 7 to ameliorate mechanical hyperalgesia in diabetic mice","volume":"259","author":"Nakatani","year":"2020","journal-title":"J. Ethnopharmacol."},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib94","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/s11062-012-9249-1","article-title":"Antinociceptive effect of salvia extract on cisplatin-induced hyperalgesia in mice","volume":"43","author":"Namvaran-Abbas-Abad","year":"2012","journal-title":"Neurophysiology"},{"issue":"7","key":"10.1016\/j.fct.2026.116163_bib95","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.pain.2011.02.051","article-title":"Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation","volume":"152","author":"Nassini","year":"2011","journal-title":"Pain\u00ae"},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib96","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/0959-8049(96)00051-2","article-title":"Glutathione and related enzymes in multidrug resistance","volume":"32A","author":"O'Brien","year":"1996","journal-title":"Eur. J. Cancer"},{"issue":"19","key":"10.1016\/j.fct.2026.116163_bib97","doi-asserted-by":"crossref","first-page":"6645","DOI":"10.1039\/C8DT00838H","article-title":"The side effects of platinum-based chemotherapy drugs: a review for chemists","volume":"47","author":"Oun","year":"2018","journal-title":"Dalton Trans."},{"key":"10.1016\/j.fct.2026.116163_bib98","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ejphar.2017.05.063","article-title":"Cisplatin induced arrhythmia; electrolyte imbalance or disturbance of the SA node?","volume":"811","author":"Oun","year":"2017","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib99","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.taap.2003.12.006","article-title":"The effect of Ginkgo extract EGb761 in cisplatin-induced peripheral neuropathy in mice","volume":"196","author":"Ozturk","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.fct.2026.116163_bib100","first-page":"12","article-title":"Biochemical and molecular mechanisms of action of cisplatin in cancer cells","author":"Petrovi\u0107","year":"2016","journal-title":"Facta Univ. \u2013 Ser. Med. Biol."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib101","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.nbd.2010.11.017","article-title":"Cisplatin induced mitochondrial DNA damage in dorsal root ganglion neurons","volume":"41","author":"Podratz","year":"2011","journal-title":"Neurobiol. Dis."},{"issue":"8","key":"10.1016\/j.fct.2026.116163_bib102","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1021\/acs.chemrestox.9b00204","article-title":"Advances in toxicological research of the anticancer drug cisplatin","volume":"32","author":"Qi","year":"2019","journal-title":"Chem. Res. Toxicol."},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib103","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1007\/s00280-017-3358-x","article-title":"Involvement of cytochrome P450 in cisplatin treatment: implications for toxicity","volume":"80","author":"Quintanilha","year":"2017","journal-title":"Cancer Chemother. Pharmacol."},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib104","doi-asserted-by":"crossref","first-page":"330","DOI":"10.4103\/0971-5851.125262","article-title":"Cisplatin induced paroxysmal supraventricular tachycardia","volume":"34","author":"Raja","year":"2013","journal-title":"Indian J. Med. Paediatr. Oncol."},{"issue":"11","key":"10.1016\/j.fct.2026.116163_bib105","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1080\/15548627.2015.1091141","article-title":"ER stress: autophagy induction, inhibition and selection","volume":"11","author":"Rashid","year":"2015","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib106","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1038\/s41598-018-38199-7","article-title":"Cisplatin enhances cell stiffness and decreases invasiveness rate in prostate cancer cells by actin accumulation","volume":"9","author":"Raudenska","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.fct.2026.116163_bib107","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.147079","article-title":"Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin-induced mechanical and thermal allodynia","volume":"1748","author":"Recalde","year":"2020","journal-title":"Brain Res."},{"key":"10.1016\/j.fct.2026.116163_bib108","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ejphar.2013.08.049","article-title":"Molecular mechanisms of 5-HT3 and NK1 receptor antagonists in prevention of emesis","volume":"722","author":"Rojas","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.fct.2026.116163_bib109","series-title":"Cisplatin: Its History and Possible Mechanisms of Action Cisplatin","first-page":"9","author":"Rosenberg","year":"1980"},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib110","first-page":"1799","article-title":"The successful regression of large solid sarcoma 180 tumors by platinum compounds","volume":"30","author":"Rosenberg","year":"1970","journal-title":"Cancer Res."},{"issue":"4972","key":"10.1016\/j.fct.2026.116163_bib111","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1038\/205698a0","article-title":"Inhibition of cell division in Escherichia coli by electrolysis products from a platinum electrode","volume":"205","author":"Rosenberg","year":"1965","journal-title":"Nature"},{"issue":"5191","key":"10.1016\/j.fct.2026.116163_bib112","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/222385a0","article-title":"Platinum compounds: a new class of potent antitumour agents","volume":"222","author":"Rosenberg","year":"1969","journal-title":"Nature"},{"issue":"10","key":"10.1016\/j.fct.2026.116163_bib113","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1002\/ptr.6442","article-title":"Efficacy of topical Citrullus colocynthis (bitter apple) extract oil in chemotherapy-induced peripheral neuropathy: a pilot double-blind randomized placebo-controlled clinical trial","volume":"33","author":"Rostami","year":"2019","journal-title":"Phytother Res."},{"issue":"Suppl. ment_1","key":"10.1016\/j.fct.2026.116163_bib114","doi-asserted-by":"crossref","first-page":"63S","DOI":"10.1093\/bja\/69.supplement_1.63S","article-title":"5-HT3 antagonists in postoperative nausea and vomiting","volume":"69","author":"Russell","year":"1992","journal-title":"Br. J. Anaesth."},{"issue":"1\u20132","key":"10.1016\/j.fct.2026.116163_bib115","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.heares.2006.09.015","article-title":"Mechanisms of cisplatin-induced ototoxicity and prevention","volume":"226","author":"Rybak","year":"2007","journal-title":"Hear. Res."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib116","doi-asserted-by":"crossref","first-page":"555","DOI":"10.14694\/EdBook_AM.2012.32.40","article-title":"Recent advances in cardiotoxicity of anticancer therapies","volume":"32","author":"Ryberg","year":"2012","journal-title":"Am Soc Clin Oncol Educ Book"},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib117","doi-asserted-by":"crossref","first-page":"839","DOI":"10.3390\/foods10040839","article-title":"Potential health benefits of plant food-derived bioactive components: an overview","volume":"10","author":"Samtiya","year":"2021","journal-title":"Foods"},{"issue":"7","key":"10.1016\/j.fct.2026.116163_bib118","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1002\/ptr.7497","article-title":"Polydatin as a therapeutic alternative for central nervous system disorders: a systematic review of animal studies","volume":"36","author":"Schimith","year":"2022","journal-title":"Phytother Res."},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib119","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.neuro.2009.01.003","article-title":"Role of MAPKs in platinum-induced neuronal apoptosis","volume":"30","author":"Scuteri","year":"2009","journal-title":"Neurotoxicology"},{"issue":"9","key":"10.1016\/j.fct.2026.116163_bib120","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.23121","article-title":"Protective effect of naringin against oxaliplatin\u2010induced peripheral neuropathy in rats: a behavioral and molecular study","volume":"36","author":"Semis","year":"2022","journal-title":"J. Biochem. Mol. Toxicol."},{"issue":"12","key":"10.1016\/j.fct.2026.116163_bib121","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1016\/j.pain.2014.09.020","article-title":"Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis","volume":"155","author":"Seretny","year":"2014","journal-title":"Pain"},{"issue":"5","key":"10.1016\/j.fct.2026.116163_bib122","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/j.neuro.2012.08.004","article-title":"Walnut consumption protects rats against cisplatin-induced neurotoxicity","volume":"33","author":"Shabani","year":"2012","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.fct.2026.116163_bib123","first-page":"1045","article-title":"Oncology trends products markets\u2013part 1","author":"Siafaca","year":"1999","journal-title":"Future Oncol."},{"issue":"16","key":"10.1016\/j.fct.2026.116163_bib124","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1056\/NEJMoa0707056","article-title":"Weekly paclitaxel in the adjuvant treatment of breast cancer","volume":"358","author":"Sparano","year":"2008","journal-title":"N. Engl. J. Med."},{"issue":"20","key":"10.1016\/j.fct.2026.116163_bib125","doi-asserted-by":"crossref","first-page":"7753","DOI":"10.3390\/ijms21207753","article-title":"Antioxidant supplementation in the treatment of neurotoxicity induced by platinum-based chemotherapeutics\u2014a review","volume":"21","author":"Stankovic","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.fct.2026.116163_bib126","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.3390\/antiox13101228","article-title":"Alpha-lipoic acid: biological mechanisms and health benefits","volume":"13","author":"Superti","year":"2024","journal-title":"Antioxidants"},{"issue":"4","key":"10.1016\/j.fct.2026.116163_bib127","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s11418-015-0921-9","article-title":"Ninjin'yoeito and ginseng extract prevent oxaliplatin-induced neurodegeneration in PC12 cells","volume":"69","author":"Suzuki","year":"2015","journal-title":"J. Nat. Med."},{"key":"10.1016\/j.fct.2026.116163_bib128","doi-asserted-by":"crossref","DOI":"10.1186\/1744-8069-6-15","article-title":"Transient receptor potential vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice","volume":"6","author":"Ta","year":"2010","journal-title":"Mol. Pain"},{"key":"10.1016\/j.fct.2026.116163_bib129","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/6564466","article-title":"Efficacy of omega-3 polyunsaturated fatty acids in patients with lung cancer undergoing radiotherapy and chemotherapy: a meta-analysis","volume":"2022","author":"Tao","year":"2022","journal-title":"Int. J. Clin. Pract."},{"issue":"10","key":"10.1016\/j.fct.2026.116163_bib130","doi-asserted-by":"crossref","first-page":"4405","DOI":"10.1523\/JNEUROSCI.3940-12.2013","article-title":"Functional mechanotransduction is required for cisplatin-induced hair cell death in the zebrafish lateral line","volume":"33","author":"Thomas","year":"2013","journal-title":"J. Neurosci."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib131","doi-asserted-by":"crossref","first-page":"146","DOI":"10.18632\/aging.100445","article-title":"The journey of resveratrol from yeast to human","volume":"4","author":"Timmers","year":"2012","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.fct.2026.116163_bib132","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.neuro.2018.09.001","article-title":"Thymoquinone prevents cisplatin neurotoxicity in primary DRG neurons","volume":"69","author":"Ustun","year":"2018","journal-title":"Neurotoxicology"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib133","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0211268","article-title":"Screening-based approach to discover effective platinum-based chemotherapies for cancers with poor prognosis","volume":"14","author":"Varbanov","year":"2019","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib134","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1039\/C2CS35259A","article-title":"Targeting and delivery of platinum-based anticancer drugs","volume":"42","author":"Wang","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.fct.2026.116163_bib135","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2023.116751","article-title":"Platinum-based chemotherapy induces demyelination of Schwann cells in oral squamous cell carcinoma treatment","volume":"481","author":"Wang","year":"2023","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib136","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.pain.2010.11.031","article-title":"Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat","volume":"152","author":"Wei","year":"2011","journal-title":"PAIN\u00ae"},{"issue":"3","key":"10.1016\/j.fct.2026.116163_bib137","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1595\/003214079X2339098","article-title":"Cisplatin in the treatment of cancer","volume":"23","author":"Wiltshaw","year":"1979","journal-title":"Platin. Met. Rev."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib138","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1186\/s12906-019-2761-8","article-title":"Ameliorative effects of aqueous extract of Forsythiae suspensa fruits on oxaliplatin-induced neurotoxicity in vitro and in vivo","volume":"19","author":"Yi","year":"2019","journal-title":"BMC Compl. Alternative Med."},{"key":"10.1016\/j.fct.2026.116163_bib139","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2019.104715","article-title":"Curcumin attenuates cognitive impairment by enhancing autophagy in chemotherapy","volume":"136","author":"Yi","year":"2020","journal-title":"Neurobiol. Dis."},{"issue":"1","key":"10.1016\/j.fct.2026.116163_bib140","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/s41467-019-08290-2","article-title":"Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs","volume":"10","author":"Yimit","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.fct.2026.116163_bib141","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.toxrep.2018.04.006","article-title":"Neuro-and nephroprotective effect of grape seed proanthocyanidin extract against carboplatin and thalidomide through modulation of inflammation, tumor suppressor protein p53, neurotransmitters, oxidative stress and histology","volume":"5","author":"Yousef","year":"2018","journal-title":"Toxicol. Rep."},{"issue":"6","key":"10.1016\/j.fct.2026.116163_bib142","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.3390\/ijms20061451","article-title":"Mechanisms of chemotherapy-induced peripheral neuropathy","volume":"20","author":"Zajaczkowska","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.fct.2026.116163_bib143","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1111\/cns.13303","article-title":"Alpha\u2010lipoic acid downregulates TRPV1 receptor via NF\u2010\u03baB and attenuates neuropathic pain in rats with diabetes","volume":"26","author":"Zhang","year":"2020","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.fct.2026.116163_bib144","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/9947191","article-title":"Polydatin attenuates cisplatin-induced acute kidney injury by inhibiting ferroptosis","volume":"2022","author":"Zhou","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"2","key":"10.1016\/j.fct.2026.116163_bib145","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1464-5491.2004.01109.x","article-title":"Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis","volume":"21","author":"Ziegler","year":"2004","journal-title":"Diabet. Med."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691526002371?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691526002371?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T02:44:56Z","timestamp":1783392296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691526002371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":145,"alternative-id":["S0278691526002371"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2026.116163","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chemotherapy-induced peripheral neuropathy: Mechanisms of toxicity and potential natural compounds-based therapeutics","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2026.116163","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116163"}}