{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:40:26Z","timestamp":1792730426829,"version":"4.5.0"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Food and Chemical Toxicology"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.fct.2026.116468","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:08:07Z","timestamp":1792624087000},"page":"116468","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Revisiting the obesogenic potential of legacy pollutants: Epidemiological, toxicogenomic, and benchmark dose-based evidence"],"prefix":"10.1016","volume":"219","author":[{"given":"Ming","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youjie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surong","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fct.2026.116468_bib1","article-title":"Hormesis induced by persistent organic pollutants: mechanisms, ecological implications, and challenges for risk assessment","volume":"388","author":"Agathokleous","year":"2025","journal-title":"Environ. Pollut."},{"issue":"8","key":"10.1016\/j.fct.2026.116468_bib2","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1007\/s10653-021-01031-9","article-title":"Atmospheric PAHs in rural, urban, industrial and beach locations in Buenos Aires province, Argentina: sources and health risk assessment","volume":"44","author":"Arias","year":"2021","journal-title":"Environ. Geochem. Health"},{"issue":"24","key":"10.1016\/j.fct.2026.116468_bib3","doi-asserted-by":"crossref","first-page":"13529","DOI":"10.1021\/acs.est.6b03783","article-title":"Contribution of persistent organic pollutant exposure to the adipose tissue oxidative microenvironment in an adult cohort: a multipollutant approach","volume":"50","author":"Artacho-Cord\u00f3n","year":"2016","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.fct.2026.116468_bib4","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1161\/CIRCRESAHA.124.324559","article-title":"Proteomics, human environmental exposure, and cardiometabolic risk","volume":"135","author":"As","year":"2024","journal-title":"Circ. Res."},{"issue":"18","key":"10.1016\/j.fct.2026.116468_bib5","doi-asserted-by":"crossref","first-page":"13241","DOI":"10.1021\/acs.est.6c02654","article-title":"At the exposome's frontier: mass spectrometry to bridge the gap between exposure and biological mechanisms","volume":"60","author":"Belova","year":"2026","journal-title":"Environ. Sci. Technol."},{"issue":"12","key":"10.1016\/j.fct.2026.116468_bib6","doi-asserted-by":"crossref","first-page":"e1105","DOI":"10.1016\/S2468-2667(24)00246-9","article-title":"Determinants of childhood obesity in China","volume":"9","author":"C","year":"2024","journal-title":"Lancet Public Health"},{"key":"10.1016\/j.fct.2026.116468_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109953","article-title":"Sex-specific association of prenatal exposure to halogenated persistent organic pollutants (Hal-POPs) with neonatal sex hormone levels and birth size: a birth cohort study using meconium as a biomonitoring matrix","volume":"206","author":"Cai","year":"2025","journal-title":"Environ. Int."},{"issue":"14","key":"10.1016\/j.fct.2026.116468_bib8","doi-asserted-by":"crossref","first-page":"9557","DOI":"10.1021\/acs.est.1c00904","article-title":"Persistent organic pollutants burden, trophic magnification and risk in a pelagic food web from coastal NW Mediterranean Sea","volume":"55","author":"Castro-Jim\u00e9nez","year":"2021","journal-title":"Environ. Sci. Technol."},{"issue":"21","key":"10.1016\/j.fct.2026.116468_bib9","doi-asserted-by":"crossref","first-page":"10167","DOI":"10.1021\/acs.est.5c01085","article-title":"Aryl organophosphate esters and hemostatic disruption: identifying risk through machine learning and experimental validation","volume":"59","author":"Chen","year":"2025","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.127044","article-title":"Environmental exposure to endocrine disruptors induces insulin resistance and hepatic inflammation in adult male rats, with partial transmission across subsequent generations","volume":"385","author":"Darracq-Ghitalla-Ciock","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.fct.2026.116468_bib11","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.tiv.2019.03.024","article-title":"Cytotoxic activity of pentachlorophenol and its active metabolites in SH-SY5Y neuroblastoma cells","volume":"58","author":"Fraser","year":"2019","journal-title":"Toxicol. Vitro"},{"issue":"4","key":"10.1016\/j.fct.2026.116468_bib12","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1021\/acs.est.3c10630","article-title":"Chasing \u201cEmerging\u201d contaminants: an endless journey toward environmental health","volume":"58","author":"Gao","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2026.124420","article-title":"Prenatal exposure to persistent organic pollutants and childhood adiposity: findings from the MIREC cohort","volume":"301","author":"Gbemavo","year":"2026","journal-title":"Environ. Res."},{"issue":"5691","key":"10.1016\/j.fct.2026.116468_bib14","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1126\/science.1095292","article-title":"Living with the past: Evolution, development, and patterns of disease","volume":"305","author":"Gluckman","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.fct.2026.116468_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106469","article-title":"Prenatal exposure to persistent organic pollutants and markers of obesity and cardiometabolic risk in Spanish adolescents","volume":"151","author":"G\u00fcil-Oumrait","year":"2021","journal-title":"Environ. Int."},{"issue":"22","key":"10.1016\/j.fct.2026.116468_bib16","doi-asserted-by":"crossref","first-page":"16158","DOI":"10.1021\/acs.est.6c01518","article-title":"Identification and spatial analysis of Co-Occurring pollution sources of HCHs, PCBs, and PFASs in the EU and potential risks of soil pollution","volume":"60","author":"Hina","year":"2026","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2023.114236","article-title":"A revised concept for deriving reference values for internal exposures to chemical substances and its application to population-representative biomonitoring data in German children and adolescents 2014\u20132017 (GerES V)","volume":"253","author":"Hoopmann","year":"2023","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.fct.2026.116468_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.124980","article-title":"Persistent organic pollutants and metabolic diseases: from the perspective of lipid droplets","volume":"362","author":"Hou","year":"2024","journal-title":"Environmental Pollution (Barking, Essex : 1987)"},{"key":"10.1016\/j.fct.2026.116468_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.142028","article-title":"Levels and profiles of persistent organic pollutants in breast milk in China and their potential health risks to breastfed infants: a review","volume":"753","author":"Hu","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.fct.2026.116468_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119980","article-title":"Accumulative levels, temporal and spatial distribution of common chemical pollutants in the blood of Chinese adults","volume":"311","author":"Kou","year":"2022","journal-title":"Environ. Pollut."},{"issue":"17","key":"10.1016\/j.fct.2026.116468_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmb.2024.168617","article-title":"GalaxySagittarius-AF: predicting targets for drug-like compounds in the extended human 3D proteome","volume":"436","author":"Kwon","year":"2024","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.fct.2026.116468_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.107846","article-title":"Human health risk assessment of 6:2 Cl-PFESA through quantitative in vitro to in vivo extrapolation by integrating cell-based assays, an epigenetic key event, and physiologically based pharmacokinetic modeling","volume":"173","author":"Li","year":"2023","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.fct.2026.116468_bib23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/s44454-026-00054-0","article-title":"An integrative framework for prioritizing high-risk chemicals in children and adolescents: elevated blood pressure as a proof-of-concept","volume":"2","author":"Li","year":"2026","journal-title":"Npj Emerging Contaminants"},{"issue":"13","key":"10.1016\/j.fct.2026.116468_bib24","doi-asserted-by":"crossref","first-page":"6414","DOI":"10.1021\/acs.est.4c12617","article-title":"Dose-response metabolomics unveils liver metabolic disruptions and pathway sensitivity to alkylimidazolium ionic liquids: benchmark dose estimation for health risk assessment","volume":"59","author":"Li","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"25","key":"10.1016\/j.fct.2026.116468_bib25","doi-asserted-by":"crossref","first-page":"17742","DOI":"10.1021\/acs.est.6c03276","article-title":"A structure-informed framework for assessing placental transfer and fetal exposure of emerging chemicals:insights from a homologous series of alkylimidazolium ionic liquids","volume":"60","author":"Li","year":"2026","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.tifs.2026.105667","article-title":"Per- and polyfluoroalkyl substances in food contact materials: Migration, health risks and sustainable alternatives","volume":"172","author":"Li","year":"2026","journal-title":"Trends Food Sci. Technol."},{"issue":"6","key":"10.1016\/j.fct.2026.116468_bib27","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1021\/envhealth.5c00501","article-title":"The association between prenatal Quaternary ammonium compounds (QACs) exposure and neonatal birth obesity: insights from epidemiology and in vitro evidence","volume":"4","author":"Lin","year":"2026","journal-title":"Environ. Health (Nagpur)"},{"issue":"13","key":"10.1016\/j.fct.2026.116468_bib28","doi-asserted-by":"crossref","first-page":"7792","DOI":"10.1021\/acs.est.9b00988","article-title":"Relative effect potency estimates for dioxin-like compounds in pregnant women with gestational diabetes mellitus and blood glucose outcomes based on a nested case-control study","volume":"53","author":"Liu","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib29","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.envpol.2016.01.022","article-title":"Global monitoring plan for persistent organic pollutants (POPs) under the Stockholm convention: triggering, streamlining and catalyzing global POPs monitoring","volume":"217","author":"Magulova","year":"2016","journal-title":"Environ. Pollut."},{"issue":"3","key":"10.1016\/j.fct.2026.116468_bib30","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1021\/es025620+","article-title":"Spatial and temporal trends of POPs in Norwegian and UK background air: implications for global cycling","volume":"37","author":"Meijer","year":"2002","journal-title":"Environ. Sci. Technol."},{"issue":"25","key":"10.1016\/j.fct.2026.116468_bib31","doi-asserted-by":"crossref","first-page":"9119","DOI":"10.1021\/acs.est.2c09353","article-title":"How many chemicals in commerce have been analyzed in environmental media? A 50 year bibliometric analysis","volume":"57","author":"Muir","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.fct.2026.116468_bib32","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1002\/etc.1854","article-title":"Environmental and human exposure to soil chlorinated and brominated polycyclic aromatic hydrocarbons in an urbanized region","volume":"31","author":"Ni","year":"2012","journal-title":"Environ. Toxicol. Chem."},{"issue":"8","key":"10.1016\/j.fct.2026.116468_bib33","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1021\/acs.estlett.4c00393","article-title":"Toxicological study of human exposure to mixtures of chemicals: challenges and approaches","volume":"11","author":"Nian","year":"2024","journal-title":"Environ. Sci. Technol. Lett."},{"issue":"4","key":"10.1016\/j.fct.2026.116468_bib34","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1038\/s41591-026-04266-0","article-title":"An atlas of exposome-phenome associations in health and disease risk","volume":"32","author":"Patel","year":"2026","journal-title":"Nat. Med."},{"key":"10.1016\/j.fct.2026.116468_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132637","article-title":"Association of hair polychlorinated biphenyls and multiclass pesticides with obesity, diabetes, hypertension and dyslipidemia in NESCAV study","volume":"461","author":"Peng","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.fct.2026.116468_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2023.114196","article-title":"Exposure of Swedish adolescents to elements, persistent organic pollutants (POPs), and rapidly excreted substances \u2013 the riksmaten adolescents 2016-17 national survey","volume":"251","author":"Pineda","year":"2023","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.fct.2026.116468_bib37","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.jsbmb.2018.01.014","article-title":"Plasticizers used in food-contact materials affect adipogenesis in 3T3-L1 cells","volume":"178","author":"Pomatto","year":"2018","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.fct.2026.116468_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109298","article-title":"Gestational exposure to environmental chemical mixtures and cognitive abilities in children: a pooled analysis of two North American birth cohorts","volume":"196","author":"Puvvula","year":"2025","journal-title":"Environ. Int."},{"issue":"22","key":"10.1016\/j.fct.2026.116468_bib39","doi-asserted-by":"crossref","first-page":"15530","DOI":"10.1021\/acs.est.6c03027","article-title":"Advancing the discovery of emerging contaminants: a leap in technology and data","volume":"60","author":"Qiu","year":"2026","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.108056","article-title":"Prenatal exposure to multiple persistent organic pollutants in association with adiposity markers and blood pressure in preadolescents","volume":"178","author":"Rouxel","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.fct.2026.116468_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2022.113972","article-title":"Internal exposure of Flemish teenagers to environmental pollutants: results of the Flemish Environment and Health Study 2016-2020 (FLEHS IV)","volume":"242","author":"Schoeters","year":"2022","journal-title":"Int. J. Hyg Environ. Health"},{"issue":"37","key":"10.1016\/j.fct.2026.116468_bib42","doi-asserted-by":"crossref","first-page":"16302","DOI":"10.1021\/acs.est.4c05235","article-title":"Longitudinal exposomics in a multiomic wellness cohort reveals distinctive and dynamic environmental chemical mixtures in blood","volume":"58","author":"Sdougkou","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib43","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1016\/j.enceco.2026.07.007","article-title":"Association between organophosphate esters and metabolic syndrome: integrated network toxicology and quantitative structure-activity relationships exploring the mechanism and combined exposure risks","volume":"8","author":"Shi","year":"2026","journal-title":"Environ. Chem. Ecotoxicol."},{"key":"10.1016\/j.fct.2026.116468_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106941","article-title":"A review of environmental metabolism disrupting chemicals and effect biomarkers associating disease risks: where exposomics meets metabolomics","volume":"158","author":"Sun","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.fct.2026.116468_bib45","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.chemosphere.2018.12.100","article-title":"Combined effects of pentachlorophenol and its byproduct hexachlorobenzene on endocrine and reproduction in zebrafish","volume":"220","author":"Sun","year":"2019","journal-title":"Chemosphere"},{"issue":"16","key":"10.1016\/j.fct.2026.116468_bib46","doi-asserted-by":"crossref","first-page":"7909","DOI":"10.1021\/acs.est.5c03560","article-title":"Are sleeping children exposed to plasticizers, flame retardants, and UV-Filters from their mattresses?","volume":"59","author":"Vaezafshar","year":"2025","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105957","article-title":"Environmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: a pilot untargeted metabolomic approach","volume":"143","author":"Valvi","year":"2020","journal-title":"Environ. Int."},{"issue":"23","key":"10.1016\/j.fct.2026.116468_bib48","doi-asserted-by":"crossref","first-page":"10001","DOI":"10.1021\/acs.est.4c00362","article-title":"Human biomonitoring of environmental chemicals among elderly in Wuhan, China: prioritizing risks using EPA's ToxCast database","volume":"58","author":"Wang","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.119650","article-title":"Network toxicology and multidimensional bioinformatics analysis reveal the shared mechanism of action of bisphenol A and phthalates in glioblastoma","volume":"309","author":"Wang","year":"2026","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"3","key":"10.1016\/j.fct.2026.116468_bib51","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1177\/13872877251405468","article-title":"Uncovering the toxicological impact of benzo[a]pyrene on Alzheimer's disease via network toxicology,machine learning,and single-cell transcriptomics","volume":"109","author":"Wang","year":"2026","journal-title":"J. Alzheimers Dis."},{"issue":"8","key":"10.1016\/j.fct.2026.116468_bib50","doi-asserted-by":"crossref","first-page":"5979","DOI":"10.1021\/acs.est.5c08003","article-title":"Environmental dose MEOHP promotes bladder cancer progress through hybrid EMT mechanism: based on the adverse outcome pathway","volume":"60","author":"Wang","year":"2026","journal-title":"Environ. Sci. Technol."},{"issue":"31","key":"10.1016\/j.fct.2026.116468_bib52","doi-asserted-by":"crossref","first-page":"13587","DOI":"10.1021\/acs.est.4c06775","article-title":"The Stockholm convention at a crossroads: questionable nominations and inadequate compliance threaten its acceptance and utility","volume":"58","author":"Wania","year":"2024","journal-title":"Environ. Sci. Technol."},{"issue":"31","key":"10.1016\/j.fct.2026.116468_bib53","doi-asserted-by":"crossref","first-page":"11583","DOI":"10.1021\/acs.est.3c00796","article-title":"Spatial and temporal trends of persistent organic pollutants across Europe after 15 years of MONET passive air sampling","volume":"57","author":"White","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"7","key":"10.1016\/j.fct.2026.116468_bib54","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1007\/s00204-026-04395-y","article-title":"PFAS-like behavior of alkylimidazolium ionic liquids: chain-length\u2013dependent toxicokinetics and PBTK-based risk implications","volume":"100","author":"Wu","year":"2026","journal-title":"Arch. Toxicol."},{"issue":"4","key":"10.1016\/j.fct.2026.116468_bib55","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1021\/envhealth.4c00120","article-title":"Benchmark dose estimation from transcriptomics data for methylimidazolium ionic liquid hepatotoxicity: implications for health risk assessment of green solvents","volume":"3","author":"Yang","year":"2025","journal-title":"Environ. Health (Nagpur)"},{"issue":"1","key":"10.1016\/j.fct.2026.116468_bib56","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1038\/s41467-024-46595-z","article-title":"An exposome atlas of serum reveals the risk of chronic diseases in the Chinese population","volume":"15","author":"You","year":"2024","journal-title":"Nat. Commun."},{"issue":"46","key":"10.1016\/j.fct.2026.116468_bib57","doi-asserted-by":"crossref","first-page":"18013","DOI":"10.1021\/acs.est.2c08558","article-title":"EDC-Predictor: a novel strategy for prediction of endocrine-disrupting chemicals by integrating pharmacological and toxicological profiles","volume":"57","author":"Yu","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"39","key":"10.1016\/j.fct.2026.116468_bib58","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ado5534","article-title":"Exploring global oceanic persistence and ecological effects of legacy persistent organic pollutants across five decades","volume":"10","author":"Zhang","year":"2024","journal-title":"Sci. Adv."},{"issue":"36","key":"10.1016\/j.fct.2026.116468_bib59","doi-asserted-by":"crossref","first-page":"25014","DOI":"10.1021\/acs.est.6c00344","article-title":"Integrating high-throughput toxicity testing with mechanistic and kinetic modeling for food chemical safety assessment","volume":"60","author":"Zhang","year":"2026","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.fct.2026.116468_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109951","article-title":"Synergistic effects of bisphenol A and its substitutes with latent insulin resistance on childhood blood pressure and the potential role of lipid metabolism","volume":"206","author":"Zhang","year":"2025","journal-title":"Environ. Int."},{"key":"10.1016\/j.fct.2026.116468_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.118077","article-title":"Associations of endocrine-disrupting chemicals mixtures with serum lipid and glucose metabolism among overweight\/obese and normal-weight children: a panel study","volume":"294","author":"Zhang","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"1","key":"10.1016\/j.fct.2026.116468_bib62","doi-asserted-by":"crossref","first-page":"7775","DOI":"10.1038\/s41467-025-63217-4","article-title":"Time to strengthen the governance of new contaminants in the environment","volume":"16","author":"Zhao","year":"2025","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.fct.2026.116468_bib63","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1021\/acs.est.5c10955","article-title":"Elevated exposure to pharmaceutical and personal care products increases hyperlipidemia risk: the mediating effect of thyroid hormones","volume":"60","author":"Zheng","year":"2025","journal-title":"Environ. Sci. Technol."}],"container-title":["Food and Chemical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691526005430?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278691526005430?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:34:01Z","timestamp":1792730041000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278691526005430"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":63,"alternative-id":["S0278691526005430"],"URL":"https:\/\/doi.org\/10.1016\/j.fct.2026.116468","relation":{},"ISSN":["0278-6915"],"issn-type":[{"value":"0278-6915","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Revisiting the obesogenic potential of legacy pollutants: Epidemiological, toxicogenomic, and benchmark dose-based evidence","name":"articletitle","label":"Article Title"},{"value":"Food and Chemical Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fct.2026.116468","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116468"}}