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The induced resistance was unstable and decreased relatively rapidly during passages in peptide free medium but the minimum inhibitory concentration remained elevated after thirty passages. Cross\u2010resistance to penicillin G and low\u2010level cross\u2010resistance to the antimicrobial peptides indolicidin and Ala<jats:sup>3,13,18<\/jats:sup>\u2010magainin was observed. No cross\u2010resistance was observed to the human cathelicidin LL\u201037. 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