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We used proteomic analysis and immunohistochemical staining to identify activin receptor\u2010like kinase\u20101 (ALK1), a type I receptor for transforming growth factor\u2010\u03b21, during the HVS regression phase. In addition, we overexpressed ALK1 in corneas implanted with bFGF (basic fibroblast growth factor) pellets and observed that ALK1 overexpression resulted in inhibition of bFGF\u2010induced corneal neovascularization in vivo. 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