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The VEGF family currently includes VEGF\u2010A, \u2010B, \u2010C, \u2010D, \u2010E, \u2010F and placenta growth factor (PlGF), that bind in a distinct pattern to three structurally related receptor tyrosine kinases, denoted VEGF receptor\u20101, \u20102, and \u20103. VEGF\u2010C and VEGF\u2010D also play a crucial role in the process of lymphangiogenesis. Here, we review the biology of VEGFs and evaluate their role in pathological angiogenesis and lymphangiogenesis.<\/jats:p>","DOI":"10.1016\/j.febslet.2006.03.087","type":"journal-article","created":{"date-parts":[[2006,4,18]],"date-time":"2006-04-18T19:18:47Z","timestamp":1145387927000},"page":"2879-2887","source":"Crossref","is-referenced-by-count":388,"title":["Biology of vascular endothelial growth 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