{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:47:45Z","timestamp":1791107265579,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2010,9,3]],"date-time":"2010-09-03T00:00:00Z","timestamp":1283472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIH PHS","award":["K22DE014847"],"award-info":[{"award-number":["K22DE014847"]}]},{"name":"NIH PHS","award":["RO1CA139596"],"award-info":[{"award-number":["RO1CA139596"]}]},{"name":"NIH PHS","award":["RO3CA135992"],"award-info":[{"award-number":["RO3CA135992"]}]},{"DOI":"10.13039\/100001299","name":"Prevent Cancer Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100001299","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[2010,9,24]]},"abstract":"<jats:p>Deregulations of microRNA have been frequently observed in tongue squamous cell carcinoma (TSCC), but their roles in tumorigenesis are not entirely clear. Here, we reported the up\u2010regulation of miR\u201024 in TSCC. MiR\u201024 up\u2010regulation reduced the expression of RNA\u2010binding protein dead end 1 (DND1). Knockdown of miR\u201024 led to enhanced expression of DND1. The direct targeting of miR\u201024 to the DND1 mRNA was predicted bioinformatically and confirmed by luciferase reporter gene assays. Furthermore, the miR\u201024\u2010mediated change in DND1 expression suppressed the expression of cyclin\u2010dependent kinase inhibitor 1B (CDKN1B), and also led to enhanced proliferation and reduced apoptosis in TSCC cells.<\/jats:p>","DOI":"10.1016\/j.febslet.2010.08.040","type":"journal-article","created":{"date-parts":[[2010,9,4]],"date-time":"2010-09-04T10:35:52Z","timestamp":1283596552000},"page":"4115-4120","source":"Crossref","is-referenced-by-count":73,"title":["MicroRNA\u201024 targeting RNA\u2010binding protein DND1 in tongue squamous cell carcinoma"],"prefix":"10.1002","volume":"584","author":[{"given":"Xiqiang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anxun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline 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