{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:45:33Z","timestamp":1772120733247,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.fertnstert.2005.04.064","type":"journal-article","created":{"date-parts":[[2005,11,6]],"date-time":"2005-11-06T07:09:24Z","timestamp":1131260964000},"page":"1517-1519","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparative genomic hybridization of ectopic pregnancies that fail methotrexate therapy"],"prefix":"10.1016","volume":"84","author":[{"given":"Laurie Jane","family":"McKenzie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hala","family":"El-Zimaity","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Krotz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo","family":"Laucirica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Carson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John E.","family":"Buster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2005.04.064_bib1","first-page":"CD000324","article-title":"Interventions for tubal ectopic pregnancy","author":"Hajenius","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib2","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/S0015-0282(16)56994-5","article-title":"Efficacy and safety of single-dose systemic methotrexate in the treatment of ectopic pregnancy","volume":"62","author":"Glock","year":"1994","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib3","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/0002-9378(93)90687-E","article-title":"Single-dose methotrexate","volume":"168","author":"Stovall","year":"1993","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib4","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/0002-9378(94)90406-5","article-title":"Single injection of methotrexate for treatment of ectopic pregnancies","volume":"171","author":"Henry","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib5","first-page":"371","article-title":"Ectopic pregnancy","volume":"40","author":"Gross","year":"1995","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib6","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1093\/oxfordjournals.humrep.a135774","article-title":"Identification of hormonal parameters for successful systemic single-dose methotrexate therapy in ectopic pregnancy","volume":"10","author":"Corsan","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib7","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1097\/00006250-199406000-00026","article-title":"Serum progesterone as a predictor of methotrexate success in the treatment of ectopic pregnancy","volume":"83","author":"Ransom","year":"1994","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1074-3804(97)80011-4","article-title":"Clinical and financial analyses of ectopic pregnancy management at a large health plan","volume":"4","author":"Hidlebaugh","year":"1997","journal-title":"J Am Assoc Gynecol Laparosc"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib9","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0015-0282(97)00284-7","article-title":"Medical treatment of ectopic pregnancy with methotrexate","volume":"68","author":"Thoen","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib10","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S0015-0282(00)01547-8","article-title":"Predictors of treatment failure for ectopic pregnancy treated with single-dose methotrexate","volume":"74","author":"Tawfiq","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib11","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ijgo.2003.11.003","article-title":"Previous ectopic pregnancy as a predictor of methotrexate failure","volume":"85","author":"Laibl","year":"2004","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib12","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1067\/mob.2003.310","article-title":"Predictors of success with methotrexate treatment of tubal ectopic pregnancy at Grady Memorial Hospital","volume":"188","author":"Potter","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib13","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.fertnstert.2004.03.066","article-title":"Characterizing ectopic pregnancies that rupture despite treatment with methotrexate","volume":"82","author":"Dudley","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib14","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/0888-7543(92)90147-K","article-title":"Degenerate oligonucleotide-primed PCR","volume":"13","author":"Telenius","year":"1992","journal-title":"Genomics"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib15","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1093\/oxfordjournals.humrep.a019207","article-title":"Cytogenetic characteristics of ectopic pregnancy","volume":"11","author":"Goddijin","year":"1996","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib16","doi-asserted-by":"crossref","first-page":"881","DOI":"10.3109\/00016349609055021","article-title":"DNA ploidy of ectopic pregnancy and first trimester spontaneous abortion investigated by flow cytometry","volume":"75","author":"Erel","year":"1996","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib17","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/S0002-9378(15)33314-7","article-title":"Chromosome analysis of ectopic human conceptuses","volume":"141","author":"Elias","year":"1981","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib18","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0028-2243(93)90184-E","article-title":"DNA aneuploidy in ectopic pregnancy and spontaneous abortions","volume":"51","author":"Toikkanen","year":"1993","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib19","first-page":"1211","article-title":"Comparative genomic hybridization in clinical cytogenetics","volume":"57","author":"Bryndorf","year":"1995","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib20","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/humrep\/13.4.805","article-title":"Detection of chromosomal aberration in fetuses arising from recurrent spontaneous abortion by comparative genomic hybridization","volume":"13","author":"Daniely","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib21","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/sj.ejhg.5200669","article-title":"Cytogenetic analyses of culture failures by comparative genomic hybridization (CGH)-re-evaluation of chromosome aberration rates in early spontaneous abortions","volume":"9","author":"Fritz","year":"2001","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib22","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/S0015-0282(00)01703-9","article-title":"Diagnosis of aneuploidy in archival, paraffin-embedded pregnancy-loss tissues by comparative genomic hybridization","volume":"75","author":"Bell","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib23","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0015-0282(02)03271-5","article-title":"First clinical application of comparative genomic hybridization and polar body testing for preimplantation genetic diagnosis of aneuploidy","volume":"78","author":"Wells","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.04.064_bib24","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/S0015-0282(03)01162-2","article-title":"Preimplantation aneuploidy screening using comparative genomic hybridization or fluorescence in situ hybridization of embryos from patients with recurrent implantation failure","volume":"80","author":"Wilton","year":"2003","journal-title":"Fertil Steril"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028205029171?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028205029171?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:12:40Z","timestamp":1758006760000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028205029171"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0015028205029171"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2005.04.064","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1088822.541928","asserted-by":"object"}]},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative genomic hybridization of ectopic pregnancies that fail methotrexate therapy","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2005.04.064","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}