{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T03:02:41Z","timestamp":1778122961103,"version":"3.51.4"},"reference-count":15,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T00:00:00Z","timestamp":1130803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1016\/j.fertnstert.2005.05.033","type":"journal-article","created":{"date-parts":[[2005,11,6]],"date-time":"2005-11-06T07:09:24Z","timestamp":1131260964000},"page":"1508.e13-1508.e16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Four pregnancies in nonmosaic Klinefelter\u2019s syndrome using cryopreserved-thawed testicular spermatozoa"],"prefix":"10.1016","volume":"84","author":[{"given":"Hiroshi","family":"Okada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumasa","family":"Goda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Muto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Maruyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsunobu","family":"Koshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeo","family":"Horie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2005.05.033_bib1","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1093\/humrep\/14.4.946","article-title":"Klinefelter syndrome in the male infertility clinic","volume":"14","author":"Okada","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib2","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0015-0282(01)02830-8","article-title":"Birth of two infants with normal karyotype after intracytoplasmic injection of sperm obtained by testicular extraction from two men with nonmosaic Klinefelter syndrome","volume":"76","author":"Poulakis","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib3","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1093\/humrep\/16.11.2347","article-title":"Pregnancy achieved following ICSI from a man with Klinefelter syndrome and spinal cord injury","volume":"16","author":"Kyono","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib4","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1093\/humrep\/15.8.1804","article-title":"A 47,XXY fetus conceived after ICSI of spermatozoa from a patient with nonmosaic Klinefelter syndrome","volume":"15","author":"Ron-El","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib5","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1056\/NEJM199802263380905","article-title":"Births after intracytoplasmic injection of sperm obtained by testicular extraction from men with nonmosaic Klinefelter syndrome","volume":"338","author":"Palermo","year":"1998","journal-title":"N Eng J Med"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib6","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/S0015-0282(99)00151-X","article-title":"Birth of twin males with normal karyotype after intracytoplasmic sperm injection with use of testicular spermatozoa from a nonmosaic patient with Klinefelter syndrome","volume":"71","author":"Nodar","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib7","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0015-0282(00)01556-9","article-title":"Sperm chromosome analysis and outcome of IVF in patients with nonmosaic Klinefelter\u2019s syndrome","volume":"74","author":"Levron","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib8","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1093\/humrep\/16.12.2616","article-title":"Outcome of ICSI using fresh and cryopreserved-thawed testicular spermatozoa in patients with nonmosaic Klinefelter syndrome","volume":"16","author":"Friedler","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib9","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/S0015-0282(00)00710-X","article-title":"Birth of healthy male twins after intracytoplasmic sperm injection of frozen-thawed testicular spermatozoa from a patient with nonmosaic Klinefelter syndrome","volume":"74","author":"Ron-El","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib10","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/S0022-5347(05)64575-2","article-title":"Conventional versus microdissection testicular sperm extraction for nonobstructive azoospermia","volume":"168","author":"Okada","year":"2002","journal-title":"J Urol"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib11","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1093\/humrep\/12.11.2447","article-title":"Delivery of normal twins following the intracytoplasmic injection of spermatozoa from a patient with 47,XXY Klinefelter syndrome","volume":"12","author":"Bourne","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib12","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1093\/humrep\/16.9.1909","article-title":"Birth of a healthy girl after ICSI with ejaculated spermatozoa from a man with nonmosaic Klinefelter syndrome","volume":"16","author":"Cruger","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib13","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/S0015-0282(97)00280-X","article-title":"Pregnancy after intracytoplasmic sperm injection with sperm from a man with a 47,XXY Klinefelter karyotype","volume":"68","author":"Hinney","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib14","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1093\/humrep\/17.4.886","article-title":"Morphometric and cytogenetic characteristics of testicular germ cells and Sertoli cell secretory function in men with nonmosaic Klinefelter syndrome","volume":"17","author":"Yamamoto","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2005.05.033_bib15","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/humrep\/14.2.368","article-title":"Birth of a healthy neonate following the intracytoplasmic injection of testicular spermatozoa from a patient with Klinefelter syndrome","volume":"14","author":"Ron-El","year":"1999","journal-title":"Hum Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028205027822?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028205027822?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:12:27Z","timestamp":1758006747000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028205027822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["S0015028205027822"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2005.05.033","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Four pregnancies in nonmosaic Klinefelter\u2019s syndrome using cryopreserved-thawed testicular spermatozoa","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2005.05.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}