{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T02:01:33Z","timestamp":1767837693518,"version":"3.49.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":5778,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1016\/j.fertnstert.2006.01.041","type":"journal-article","created":{"date-parts":[[2006,6,13]],"date-time":"2006-06-13T10:20:58Z","timestamp":1150194058000},"page":"433-439","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Localization of angiotensin II, the AT1 receptor, angiotensin-converting enzyme, aminopeptidase A, adipocyte-derived leucine aminopeptidase, and vascular endothelial growth factor in the human ovary throughout the menstrual cycle"],"prefix":"10.1016","volume":"86","author":[{"given":"Toko","family":"Harata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisao","family":"Ando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Iwase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuro","family":"Nagasaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigehiko","family":"Mizutani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumitaka","family":"Kikkawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2006.01.041_bib1","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/humrep\/13.4.953","article-title":"Cyclic changes of vasculature and vascular phenotypes in normal human ovaries","volume":"13","author":"Suzuki","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib2","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1177\/107155769400100204","article-title":"The basis and evidence of a role for the ovarian renin-angiotensin system in health and disease","volume":"1","author":"Nemeth","year":"1994","journal-title":"J Soc Gynecol Investig"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib3","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1161\/01.RES.87.5.e1","article-title":"A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9","volume":"87","author":"Donoghue","year":"2000","journal-title":"Circ Res"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib4","doi-asserted-by":"crossref","first-page":"33238","DOI":"10.1074\/jbc.M002615200","article-title":"A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase","volume":"275","author":"Tipnis","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib5","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/0006-2952(65)90089-4","article-title":"Serum aminopeptidases, \u201cangiotensinase,\u201d and hypertension: I. Degradation of angiotensin II by human serum","volume":"14","author":"Nagatsu","year":"1965","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib6","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1093\/oxfordjournals.jbchem.a022371","article-title":"Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase\/oxytocinase","volume":"125","author":"Hattori","year":"1999","journal-title":"J Biochem (Tokyo)"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib7","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1210\/jcem-62-3-613","article-title":"Angiotensin II-like immunoreactivity in human ovarian follicular fluid","volume":"62","author":"Culler","year":"1986","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib8","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/S0196-9781(96)00184-2","article-title":"Bioactive angiotensin (1-8) is the main component of angiotensin II immunoreactivity in human follicular fluid","volume":"17","author":"Delbaere","year":"1996","journal-title":"Peptides"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0002-9378(89)90077-X","article-title":"Immunohistochemical localization of renin and angiotensin II in human ovaries","volume":"160","author":"Palumbo","year":"1989","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib10","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0009-8981(85)90207-4","article-title":"Distribution of angiotensin converting enzyme in human tissues","volume":"147","author":"van Sande","year":"1985","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib11","doi-asserted-by":"crossref","first-page":"26765","DOI":"10.1016\/S0021-9258(19)61441-9","article-title":"Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1 alpha in vascular smooth muscle cells","volume":"275","author":"Richard","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib12","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1161\/01.RES.82.5.619","article-title":"Angiotensin II potentiates vascular endothelial growth factor-induced angiogenic activity in retinal microcapillary endothelial cells","volume":"82","author":"Otani","year":"1998","journal-title":"Circ Res"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib13","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1210\/endo.137.4.8625890","article-title":"Angiotensin II induces ovulation and oocyte maturation in rabbit ovaries via the AT2 receptor subtype","volume":"137","author":"Yoshimura","year":"1996","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib14","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1093\/humrep\/deg268","article-title":"Dual renin-angiotensin blockade therapy in patients at high risk of early ovarian hyperstimulation syndrome receiving IVF and elective embryo cryopreservation","volume":"18","author":"Ando","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0015-0282(16)55630-1","article-title":"Effect of angiotensin II on human luteinized granulosa cells","volume":"59","author":"Rainey","year":"1993","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib16","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1210\/jcem.87.5.8465","article-title":"Premenstrual disappearance of aminopeptidase A in endometrial stromal cells around endometrial spiral arteries\/arterioles during the decidual change","volume":"87","author":"Ando","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib17","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1369\/jhc.3A6216.2004","article-title":"Distribution of adipocyte-derived leucine aminopeptidase (A-LAP)\/ER-aminopeptidase (ERAP)-1 in human uterine endometrium","volume":"52","author":"Shibata","year":"2004","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib18","doi-asserted-by":"crossref","first-page":"3845","DOI":"10.1210\/jcem.84.10.6025","article-title":"The vascular endothelial growth factor\/fms-like tyrosine kinase system in human ovary during the menstrual cycle and early pregnancy","volume":"84","author":"Otani","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib19","first-page":"3919","article-title":"Expression of vascular endothelial growth factor and its receptors in the human corpus luteum during the menstrual cycle and in early pregnancy","volume":"85","author":"Sugino","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib20","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0008-6363(96)00063-6","article-title":"Pericytes in the microvasculature","volume":"32","author":"Hirsschi","year":"1996","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib21","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1002\/(SICI)1096-9896(199608)179:4<436::AID-PATH611>3.0.CO;2-A","article-title":"Aminopeptidase A is a constituent of activated pericytes in angiogenesis","volume":"179","author":"Schlingemann","year":"1996","journal-title":"J Path"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib22","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1006\/frne.1997.0152","article-title":"The ovarian renin-angiotensin system in reproductive physiology","volume":"18","author":"Yoshimura","year":"1997","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib23","first-page":"i39","article-title":"RAS blockade therapy to prevent early OHSS","volume":"19","author":"Ando","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib24","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0140-6736(94)93001-5","article-title":"Vascular endothelial growth factor as capillary permeability agent in ovarian hyperstimulation syndrome","volume":"344","author":"McClure","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2006.01.041_bib25","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1095\/biolreprod60.5.1104","article-title":"Angiotensin II interacts with prostaglandin F2 alpha and endothelin-1 as a local luteolytic factor in the bovine corpus luteum in vitro","volume":"60","author":"Hayashi","year":"1999","journal-title":"Biol Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820600923X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820600923X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:15:24Z","timestamp":1758006924000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001502820600923X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["S001502820600923X"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2006.01.041","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Localization of angiotensin II, the AT1 receptor, angiotensin-converting enzyme, aminopeptidase A, adipocyte-derived leucine aminopeptidase, and vascular endothelial growth factor in the human ovary throughout the menstrual cycle","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2006.01.041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}