{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:38:18Z","timestamp":1791664698857,"version":"4.3.4"},"reference-count":52,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":5656,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1016\/j.fertnstert.2006.05.032","type":"journal-article","created":{"date-parts":[[2006,10,26]],"date-time":"2006-10-26T07:16:59Z","timestamp":1161847019000},"page":"1642-1649","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":124,"title":["Proximal tubal occlusion and salpingectomy result in similar improvement in in vitro fertilization outcome in patients with hydrosalpinx"],"prefix":"10.1016","volume":"86","author":[{"given":"Antonios","family":"Kontoravdis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelos","family":"Makrakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Pantos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Botsis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efthimios","family":"Deligeoroglou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Creatsas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2006.05.032_bib1","first-page":"29","article-title":"Diagnosis of female infertility","volume":"34","author":"Serafini","year":"1989","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0015-0282(99)00014-X","article-title":"Pathophysiology and management of proximal tubal blockage","volume":"71","author":"Honore","year":"1999","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib3","first-page":"591","article-title":"Factors influencing the success of salpingostomy techniques for distal fimbrial obstruction","volume":"52","author":"Rock","year":"1978","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib4","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1093\/oxfordjournals.humrep.a138606","article-title":"Hydrosalpinx reduces in-vitro fertilization\/embryo transfer pregnancy rates","volume":"9","author":"Strandell","year":"1994","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib5","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1093\/oxfordjournals.humrep.a138362","article-title":"Low implantation rate after in-vitro fertilization in patients with hydrosalpinges diagnosed by ultrasonography","volume":"9","author":"Andersen","year":"1994","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib6","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/oxfordjournals.humrep.a135992","article-title":"Hydrosalpinges in in-vitro fertilization: an unfavourable prognostic feature","volume":"10","author":"Vandromme","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib7","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1471-0528.1996.tb09717.x","article-title":"Impaired implantation after in vitro fertilisation treatment associated with hydrosalpinx","volume":"103","author":"Fleming","year":"1996","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0028-2243(94)90269-0","article-title":"Reduced pregnancy outcome in patients with unilateral or bilateral hydrosalpinx after in vitro fertilization","volume":"56","author":"Kassabji","year":"1994","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib9","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1023\/A:1021123309392","article-title":"The presence of hydrosalpinx may not adversely affect the implantation and pregnancy rates in in vitro fertilization treatment","volume":"14","author":"Ng","year":"1997","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib10","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0015-0282(16)58652-X","article-title":"Hydrosalpinx fluid has embryotoxic effects on murine embryogenesis: a case for prophylactic salpingectomy","volume":"66","author":"Mukherjee","year":"1996","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib11","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S0015-0282(97)00319-1","article-title":"Effect of human hydrosalpinx fluid on murine embryo development and implantation","volume":"68","author":"Rawe","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib12","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1093\/humrep\/12.12.2724","article-title":"Hydrosalpingeal fluid inhibits in-vitro embryonic development in a murine model","volume":"12","author":"Beyler","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib13","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0015-0282(97)00238-0","article-title":"Detrimental effect of hydrosalpinx fluid on the development and blastulation of mouse embryos in vitro","volume":"68","author":"Sachdev","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib14","first-page":"359","article-title":"In vivo tumor necrosis factor production in women with salpingitis","volume":"174","author":"Toth","year":"1992","journal-title":"Surg Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib15","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/humrep\/13.10.2921","article-title":"Hydrosalpinx fluid does not adversely affect the normal development of human embryos and implantation in vitro","volume":"13","author":"Strandell","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib16","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1093\/humrep\/13.6.1620","article-title":"Is hydrosalpinx fluid cytotoxic?","volume":"13","author":"Granot","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib17","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0015-0282(16)57422-6","article-title":"Integrins as markers of uterine receptivity in women with primary unexplained infertility","volume":"63","author":"Lessey","year":"1995","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib18","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1093\/humrep\/12.7.1393","article-title":"Hydrosalpinges adversely affect markers of endometrial receptivity","volume":"12","author":"Meyer","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib19","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1093\/humrep\/14.4.1087","article-title":"Hydrosalpinges adversely affect implantation in donor oocyte cycles","volume":"14","author":"Cohen","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib20","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF01131707","article-title":"Fluid accumulation of the uterine cavity before embryo transfer: a possible hindrance for implantation","volume":"8","author":"Mansour","year":"1991","journal-title":"J In Vitro Fert Embryo Transf"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib21","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1093\/humrep\/14.3.577","article-title":"The role of hydrosalpinx in IVF: simply mechanical?","volume":"14","author":"Sharara","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib22","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1093\/humrep\/12.11.2504","article-title":"Inhibitory effect of human hydrosalpingeal fluid on mouse preimplantation embryonic development is significantly reduced by the addition of lactate","volume":"12","author":"Murray","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib23","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0015-0282(97)00447-0","article-title":"The adverse effect of hydrosalpinges on in vitro fertilization pregnancy rates and the benefit of surgical correction","volume":"69","author":"Murray","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib24","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1093\/humrep\/13.10.2852","article-title":"A second look at the embryotoxicity of hydrosalpingeal fluid: an in-vitro assessment in a murine model","volume":"13","author":"Koong","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib25","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/S0015-0282(98)00077-6","article-title":"Does previous salpingectomy improve implantation and pregnancy rates in patients with severe tubal factor infertility who are undergoing in vitro fertilization?","volume":"69","author":"Dechaud","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib26","doi-asserted-by":"crossref","first-page":"2762","DOI":"10.1093\/humrep\/14.11.2762","article-title":"Hydrosalpinx and IVF outcome: a prospective, randomized multicentre trial in Scandinavia on salpingectomy prior to IVF","volume":"14","author":"Strandell","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib27","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/humrep\/17.3.543","article-title":"Laparoscopic salpingectomy for women with hydrosalpinges enhances the success of IVF: a Cochrane review","volume":"17","author":"Johnson","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib28","series-title":"Infertility: evaluation and treatment","first-page":"539","article-title":"Surgical treatment of diseases of the ovary","author":"San Filippo","year":"1995"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib29","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0015-0282(00)01742-8","article-title":"Laparoscopic management of hydrosalpinges before in vitro fertilization-embryo transfer: salpingectomy versus proximal tubal occlusion","volume":"75","author":"Surrey","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib30","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1067\/mob.2000.107671","article-title":"Cauterization of hydrosalpinges before in vitro fertilization is an effective surgical treatment associated with improved pregnancy rates","volume":"183","author":"Stadtmauer","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib31","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1093\/oxfordjournals.humrep.a019287","article-title":"Hydrosalpinx affects the implantation of previously cryopreserved embryos","volume":"11","author":"Akman","year":"1996","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib32","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/S0015-0282(16)58398-8","article-title":"Deleterious effect of the presence of hydrosalpinx on implantation and pregnancy rates with in vitro fertilization","volume":"66","author":"Katz","year":"1996","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib33","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0015-0282(97)00484-6","article-title":"The significance of hydrosalpinx in in vitro fertilization","volume":"69","author":"Nackley","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib34","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/S0015-0282(97)00405-6","article-title":"Does hydrosalpinx reduce the pregnancy rate after in vitro fertilization?","volume":"68","author":"Wainer","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib35","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1093\/HUMREP\/11.3.526","article-title":"In-vitro fertilization outcome in women with hydrosalpinx","volume":"11","author":"Sharara","year":"1996","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib36","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0015-0282(97)80079-9","article-title":"The impact of hydrosalpinx on successful pregnancy in tubal factor infertility treated by in vitro fertilization","volume":"67","author":"Blazar","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib37","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1093\/humrep\/14.5.1243","article-title":"Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: a meta-analysis of published comparative studies","volume":"14","author":"Camus","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib38","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0015-0282(98)00200-3","article-title":"Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization-embryo transfer","volume":"70","author":"Zeyneloglu","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib39","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/HUMREP\/11.3.523","article-title":"Salpingectomy improves the pregnancy rate in in-vitro fertilization patients with hydrosalpinx","volume":"11","author":"Shelton","year":"1996","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib40","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1093\/oxfordjournals.humrep.a138369","article-title":"Heterotopic pregnancy obtained after in-vitro fertilization and embryo transfer following bilateral total salpingectomy: case report","volume":"9","author":"Sharif","year":"1994","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib41","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1093\/oxfordjournals.humrep.a137504","article-title":"The dilemma of the optimal surgical procedure in ectopic pregnancies occurring in in-vitro fertilization","volume":"6","author":"Herman","year":"1991","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib42","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/humrep\/15.2.264","article-title":"Evidence for the involvement of blood flow-related mechanisms in the ovulatory process of the rat","volume":"15","author":"Zackrisson","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib43","first-page":"827","article-title":"Decreasing the number of ovulations in the rabbit with surgical division of the blood vessels between the fallopian tube and ovary","volume":"29","author":"McComb","year":"1984","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib44","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/humrep\/14.1.101","article-title":"Delivery rates after in-vitro fertilization following bilateral salpingectomy due to hydrosalpinges: a case control study","volume":"14","author":"Bredkjaer","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib45","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0015-0282(98)00357-4","article-title":"Effect of salpingectomy on ovarian response to superovulation in an in vitro fertilization-embryo transfer program","volume":"70","author":"Lass","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib46","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1093\/humrep\/13.4.983","article-title":"Permanent impairment of embryo development by hydrosalpinges","volume":"13","author":"Freeman","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib47","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0015-0282(16)53287-7","article-title":"Transvaginal ultrasonic needle guided aspiration of pelvic inflammatory cystic masses before ovulation induction for in vitro fertilization","volume":"53","author":"Aboulghar","year":"1990","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib48","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/humrep\/13.3.736","article-title":"Ultrasound-guided aspiration of hydrosalpinges is associated with improved pregnancy and implantation rates after in-vitro fertilization cycles","volume":"13","author":"Van Voorhis","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib49","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1093\/humrep\/12.10.2147","article-title":"Is the outcome of in-vitro fertilization and embryo transfer treatment improved by spontaneous or surgical drainage of a hydrosalpinx?","volume":"12","author":"Sowter","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib50","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1093\/humrep\/12.4.703","article-title":"Recurrence of hydrosalpinges after transvaginal aspiration of tubal fluid in an IVF cycle with development of a serometra","volume":"12","author":"Bloechle","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib51","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/00001703-200106000-00006","article-title":"Hydrosalpinx and assisted reproduction: options and rationale for treatment","volume":"13","author":"Zeyneloglu","year":"2001","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2006.05.032_bib52","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/humrep\/13.6.1696","article-title":"Only hydrosalpinges visible on ultrasound are associated with reduced implantation and pregnancy rates after in-vitro fertilization","volume":"13","author":"de Wit","year":"1998","journal-title":"Hum Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820603038X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820603038X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:15:44Z","timestamp":1758006944000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001502820603038X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["S001502820603038X"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2006.05.032","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2006,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Proximal tubal occlusion and salpingectomy result in similar improvement in in vitro fertilization outcome in patients with hydrosalpinx","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2006.05.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}