{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:14:26Z","timestamp":1792512866028,"version":"4.5.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":5382,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.fertnstert.2007.02.014","type":"journal-article","created":{"date-parts":[[2007,6,8]],"date-time":"2007-06-08T12:54:26Z","timestamp":1181307266000},"page":"539-546","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":185,"title":["Mullerian Inhibiting Substance is an ovarian growth factor of emerging clinical significance"],"prefix":"10.1016","volume":"88","author":[{"given":"David B.","family":"Seifer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"MacLaughlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2007.02.014_bib1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.mce.2003.09.009","article-title":"Enhanced purification and production of mullerian inhibiting substance for diagnostic and therapeutic applications","volume":"211","author":"Donahoe","year":"2003","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib2","first-page":"347","article-title":"Testicular antimullerian hormone: history, genetics, regulation and clinical applications","volume":"3","author":"Josso","year":"2006","journal-title":"Pediatr Endocrinol Rev"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib3","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1159\/000132332","article-title":"Mapping of the gene for antimullerian hormone to the short arm of human chromosome 19","volume":"44","author":"Cohen-Haguenauer","year":"1987","journal-title":"Cytogenet Cell Genet"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib4","first-page":"271","article-title":"Recherches sur la differentiation sexuelle de l'embryon de lapin","volume":"36","author":"Jost","year":"1947","journal-title":"Arch Anat Microsc Morphol Exp"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib5","first-page":"379","article-title":"Problems of fetal endocrinology: the gonadal and hypophyseal hormones","volume":"8","author":"Jost","year":"1953","journal-title":"Recent Prog Horm Res"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib6","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1095\/biolreprod15.3.329","article-title":"The production of mullerian inhibiting substance by the fetal, neonatal and adult rat","volume":"15","author":"Donahoe","year":"1976","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib7","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1210\/jcem-34-2-265","article-title":"Permeability of membranes to the mullerian-inhibiting substance synthesized by the human fetal testis in vitro: a clue to its biochemical nature","volume":"34","author":"Josso","year":"1972","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib8","first-page":"711","article-title":"Gonadotropin-releasing hormone agonist\u2013induced differences in granulosa cell cycle kinetics are associated with alterations in follicular fluid mullerian-inhibiting substance and androgen content","volume":"73","author":"Seifer","year":"1993","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib9","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.4049\/jimmunol.128.3.1327","article-title":"Monoclonal antibody to mullerian inhibiting substance","volume":"128","author":"Mudgett-Hunter","year":"1982","journal-title":"J Immunol"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib10","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1210\/endo-110-1-131","article-title":"A monoclonal antibody against bovine antim\u00fcllerian hormone","volume":"110","author":"Vigier","year":"1982","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib11","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1210\/jcem-70-1-11","article-title":"Serum levels of mullerian inhibiting substance in boys from birth to 18, as determined by enzyme immunoassay","volume":"70","author":"Baker","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib12","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1210\/jcem-70-1-16","article-title":"An immunoassay to detect human m\u00fcllerian inhibiting substance in males and females during normal development","volume":"70","author":"Hudson","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib13","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1210\/jcem-70-1-23","article-title":"An enzyme linked immunoassay for antimullerian hormone: a new tool for the evaluation of testicular function in infants and children","volume":"70","author":"Josso","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib14","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0092-8674(86)90783-X","article-title":"Isolation of the bovine human genes for mullerian inhibiting substance and expression of the human gene in animal cells","volume":"4","author":"Cate","year":"1986","journal-title":"Cell"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib15","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.mce.2003.09.015","article-title":"Inhibition of steroidogenesis in leydig cells by mullerian-inhibiting substance","volume":"211","author":"Fynn-Thompson","year":"2003","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib16","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jsbmb.2004.07.002","article-title":"Steroidogenic activities in MA-10 Leydig cells are differentially altered by cAMP and mullerian inhibiting substance","volume":"92","author":"Trbovich","year":"2004","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib17","first-page":"911","article-title":"The effects of m\u00fcllerian inhibiting substance on epidermal growth factor induced proliferation and progesterone production of human granulosa-luteal cells","volume":"75","author":"Kim","year":"1992","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib18","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1210\/endo.143.3.8691","article-title":"Anti-mullerian hormone inhibits intiation of primordial follicle grown in the mouse ovary","volume":"143","author":"Durlinger","year":"2002","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib19","first-page":"3836","article-title":"Expression of antimullerian hormone during normal and pathological gonadal development: association with differentiation of Sertoli and granulosa cells","volume":"84","author":"Rajpert-De Meyts","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib20","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/molehr\/gah015","article-title":"Anti-mullerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment","volume":"10","author":"Weenen","year":"2004","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib21","doi-asserted-by":"crossref","first-page":"15601","DOI":"10.1073\/pnas.2636900100","article-title":"Mullerian inhibiting substance inhibits cervical cancer cell growth via a pathway involving p130 and p107","volume":"100","author":"Barbie","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib22","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1073\/pnas.0407772101","article-title":"Endometrial cancer is a receptor mediated target for mullerian inhibiting substance","volume":"102","author":"Renaud","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib23","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.1210\/endo.140.12.7204","article-title":"Control of primordial follicle recruitment by antimullerian hormone in the mouse ovary","volume":"140","author":"Durlinger","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib24","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0015-0282(01)02993-4","article-title":"Anti-mullerian hormone serum levels: a putative marker for ovarian aging","volume":"77","author":"de Vet","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib25","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.fertnstert.2004.11.029","article-title":"Serum antimullerian hormone levels best reflect the reproductive decline with age in normal women with proven fertility: a longitudinal study","volume":"83","author":"van Rooij","year":"2005","journal-title":"Fertil Sertil"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib26","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1479-828X.2005.00332.x","article-title":"Anti-mullerian hormone as a marker of ovarian reserve","volume":"45","author":"Tremellen","year":"2005","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib27","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1097\/01.GME.0000123642.76105.6E","article-title":"Anti-mullerian hormone is a promising predictor for the occurrence of the menopausal transition","volume":"11","author":"van Rooij","year":"2004","journal-title":"Menopause"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib28","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.fertnstert.2006.05.074","article-title":"Association of antimullerian hormone levels with obesity in late reproductive-age women","volume":"87","author":"Freeman","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib29","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1093\/humrep\/17.12.3065","article-title":"Serum antimullerian hormone levels: a novel measure of ovarian reserve","volume":"17","author":"van Rooij","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib30","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1093\/humrep\/deg043","article-title":"Serum antimullerian hormone dynamics during controlled ovarian hyperstimulation","volume":"18","author":"Fanchin","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib31","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1093\/humrep\/deh819","article-title":"Anti-mullerian hormone concentrations in maternal serum during pregnancy","volume":"20","author":"La Marca","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib32","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0015-0282(99)00639-1","article-title":"Serum mullerian inhibiting substance levels during normal menstrual cycles","volume":"73","author":"Cook","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib33","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1093\/humrep\/deh508","article-title":"Anti-mullerian hormone plasma levels in spontaneous menstrual cycle and during treatment with FSH to induce ovulation","volume":"19","author":"La Marca","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib34","doi-asserted-by":"crossref","first-page":"4057","DOI":"10.1210\/jc.2006-0331","article-title":"Anti-mullerian hormone levels in the spontaneous menstrual cycle do not show substantial fluctuation","volume":"91","author":"Hehenkamp","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib35","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1093\/humrep\/del291","article-title":"Serum anti-mullerian hormone throughout the human menstrual cycle","volume":"21","author":"La Marca","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib36","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/humrep\/deh688","article-title":"High Reproducibility of serum antimullerian hormone measurements suggests a multi-staged follicular secretion and strengthens its role in the assessment of ovarian follicular status","volume":"20","author":"Fanchin","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib37","unstructured":"Seifer DB, Golub ET, Lambert-Messerlian G, Springer G, Holman S, Moxley M, et\u00a0al. Biologic markers of ovarian reserve and reproductive aging: application in a cohort study of HIV infection in women. Fertil Steril. In press."},{"key":"10.1016\/j.fertnstert.2007.02.014_bib38","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1093\/humrep\/del421","article-title":"Anti-mullerian hormone measurement on any day of the menstrual cycle strongly predicts ovarian response in assisted reproductive technology","volume":"22","author":"La Marca","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib39","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0015-0282(01)03201-0","article-title":"Early follicular serum mullerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles","volume":"77","author":"Seifer","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib40","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1093\/humrep\/deg042","article-title":"Serum antimullerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3","volume":"18","author":"Fanchin","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib41","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1111\/j.1471-0528.2005.00670.x","article-title":"Antral follicle count, antimullerian hormone and inhibin B: predictors of ovarian response in assisted reproductive technology?","volume":"112","author":"Muttukrishna","year":"2005","journal-title":"Br\u00a0J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib42","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1111\/j.1471-0528.2004.00452.x","article-title":"Inhibin B and antimullerian hormone: markers of ovarian response in IVF\/ICSI patients?","volume":"111","author":"Muttukrishna","year":"2004","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib43","doi-asserted-by":"crossref","first-page":"4064","DOI":"10.1210\/jc.2006-1066","article-title":"Estradiol and regulation of antimullerian hormone, inhibin-A and inhibin-B secretion: analysis of small antral and preovulatory human follicles' fluid","volume":"91","author":"Andersen","year":"2006","journal-title":"J Clin Endorinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib44","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.fertnstert.2004.03.061","article-title":"Serum antimullerian hormone\/mullerian inhibiting substance appears to be a more discriminatory marker of ART outcome than follicular stimulating hormone, inhibin B or estradiol","volume":"82","author":"Hazout","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib45","doi-asserted-by":"crossref","first-page":"3178","DOI":"10.1093\/humrep\/dei203","article-title":"Dynamic assays of inhibin B, antimullerian hormone and estradiol following FSH stimulation and ovarian ultrasonography as predictors of IVF outcome","volume":"20","author":"Eldar-Geva","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib46","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1093\/humrep\/deh718","article-title":"Basal and stimulation day 5 antimullerian hormone serum concentrations as predictors of ovarian response and pregnancy in assisted reproductive technology cycles stimulated with gonadotropin-releasing hormone agonist\u2013gonadotropin treatment","volume":"20","author":"Penarrubia","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib47","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.fertnstert.2005.09.019","article-title":"Early follicular antimullerian hormone as an indicator of ovarian reserve","volume":"85","author":"Ficicioglu","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib48","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1093\/humrep\/del127","article-title":"Basal level antimullerian hormone is associated with oocyte quality in stimulated cycles","volume":"21","author":"Ebner","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib49","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/humrep\/dei270","article-title":"mullerian inhibitory substance levels at the time of hCG administration in IVF cycles predict both ovarian reserve and embryo morphology","volume":"21","author":"Silberstein","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib50","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.fertnstert.2006.06.019","article-title":"Antimullerian hormone predicts ovarian responsiveness, but not embryo quality or pregnancy, after in vitro fertilization or intracyoplasmic sperm injection","volume":"87","author":"Smeenk","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib51","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1093\/humrep\/deg473","article-title":"Depletion of the ovarian reserve in young women following treatment for cancer in childhood: detection by antimullerian hormone, inhibin B and ovarian ultrasound","volume":"18","author":"Bath","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib52","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1093\/humrep\/del201","article-title":"The effects of chemotherapy and long-term gonadotrophin suppression on the ovarian reserve in premenopausal women with breast cancer","volume":"21","author":"Anderson","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib53","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/j.fertnstert.2005.10.052","article-title":"Elevated serum mullerian-inhibiting substance may be a marker for ovarian hyperstimulation syndrome in normal women undergoing in vitro fertilization","volume":"85","author":"Nakhuda","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib54","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/S0015-0282(97)81417-3","article-title":"Mullerian Inhibiting Substance in follicular fluid and serum: a comparison of patients with tubal factor infertility, polycystic ovary syndrome, and endometriosis","volume":"67","author":"Fallat","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib55","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0015-0282(01)02944-2","article-title":"Relationship between serum mullerian-inhibiting substance and other reproductive hormones and other reproductive hormones in untreated women and polycystic ovary syndrome and normal women","volume":"77","author":"Cook","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib56","doi-asserted-by":"crossref","first-page":"5957","DOI":"10.1210\/jc.2003-030727","article-title":"Elevated serum level of antimullerian hormone in patients with polycystic ovary syndrome: relationship to the ovarian follicle excess and the follicular arrest","volume":"88","author":"Pigny","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib57","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1210\/jc.2005-2076","article-title":"Serum anti-mullerian hormone as a surrogate for antral follicle count for definition of the polycystic ovary syndrome","volume":"91","author":"Pigny","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib58","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1210\/jc.2003-030932","article-title":"Anti-mullerian hormone serum concentrations in normoovulatory and anovulatory women of reproductive age","volume":"89","author":"Laven","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib59","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1016\/j.fertnstert.2005.06.026","article-title":"Mullerian Inhibiting Substance reflects ovarian findings in women with polycystic ovary syndrome better than does inhibin B","volume":"84","author":"Chu","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib60","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.fertnstert.2005.02.052","article-title":"Serum mullerian-inhibiting substance levels in adolescent girls with normal menstrual cycles or with polycystic ovary syndrome","volume":"84","author":"Siow","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib61","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1210\/jc.2005-2693","article-title":"Increased antimullerian hormone serum concentrations in prepubertal daughters of women with polycystic ovary syndrome","volume":"91","author":"Sir-Petermann","year":"2006","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib62","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.fertnstert.2004.05.098","article-title":"Metformin reduces serum mullerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatment","volume":"83","author":"Fleming","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib63","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1093\/humrep\/deh850","article-title":"Serum antimullerian hormone levels remain high until late reproductive age and decrease during metformin therapy in women with polycystic ovary syndrome","volume":"20","author":"Piltonen","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib64","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1093\/humrep\/deh373","article-title":"Changes in antimullerian hormone serum concentrations over time suggest delayed ovarian aging in normogonadotrophic anovulatory infertility","volume":"9","author":"Mulders","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.02.014_bib65","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1210\/jc.2006-1582","article-title":"Granulosa cell production of antimullerian hormone is increased in polycystic ovaries","volume":"92","author":"Pellatt","year":"2007","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028207003524?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028207003524?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:18:30Z","timestamp":1758007110000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028207003524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":65,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S0015028207003524"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2007.02.014","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mullerian Inhibiting Substance is an ovarian growth factor of emerging clinical significance","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2007.02.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}