{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T12:11:40Z","timestamp":1771503100676,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T00:00:00Z","timestamp":1662940800000},"content-version":"vor","delay-in-days":5124,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1016\/j.fertnstert.2007.07.1387","type":"journal-article","created":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T03:03:34Z","timestamp":1196478214000},"page":"850.e5-850.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Assisted reproduction treatment in severe myasthenia gravis"],"prefix":"10.1016","volume":"90","author":[{"given":"Giuseppe","family":"Ricci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"De Santis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Pagnini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo Fischer","family":"Tamaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Giolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Secondo","family":"Guaschino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2007.07.1387_bib1","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.1172\/JCI29894","article-title":"Myasthenia gravis: past, present, and future","volume":"116","author":"Conti-Fine","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib2","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/nri916","article-title":"Unravelling the pathogenesis of myasthenia gravis","volume":"2","author":"Vincent","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib3","first-page":"531","article-title":"Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action","volume":"121","author":"Ansar Ahmed","year":"1985","journal-title":"Am J Pathol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib4","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1006\/clin.1993.1026","article-title":"Subset-specific effects of sex hormones and pituitary gonadotropins on human lymphocyte proliferation in vitro","volume":"66","author":"Athreya","year":"1993","journal-title":"Clin Immunol Immunopathol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib5","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0022-510X(98)00031-8","article-title":"Exacerbation of myasthenia gravis during the menstrual period","volume":"156","author":"Leker","year":"1998","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib6","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0002-9378(16)32998-2","article-title":"Myasthenia gravis in pregnancy: an update","volume":"135","author":"Plauche","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib7","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1126\/science.283.5406.1277","article-title":"A gender gap in autoimmunity","volume":"283","author":"Whitacre","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib8","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/ni0901-777","article-title":"Sex differences in autoimmune disease","volume":"2","author":"Whitacre","year":"2001","journal-title":"Nat Immunol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib9","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S1567-5769(01)00044-3","article-title":"Sex hormones as immunomodulators in health and disease","volume":"1","author":"Verthelyi","year":"2001","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib10","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0928-8244(03)00202-5","article-title":"Regulation of innate and adaptive immunity by the female sex hormones oestradiol and progesterone","volume":"38","author":"Beagley","year":"2003","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib11","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1210\/en.2005-1469","article-title":"Female's heightened immune status: estrogen, T cells, and inducible nitric oxide synthase in the balance","volume":"147","author":"Verthelyi","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib12","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1210\/en.2004-1003","article-title":"Diffential estrogen receptor expression in autoimmune myasthenia gravis","volume":"146","author":"Nancy","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib13","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/01.grf.0000153206.85996.07","article-title":"Myasthenia gravis and pregnancy","volume":"48","author":"Stafford","year":"2005","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib14","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1212\/WNL.52.3.447","article-title":"Course and treatment of myasthenia gravis during pregnancy","volume":"52","author":"Batocchi","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0301-2115(02)00051-9","article-title":"Myasthenia gravis in pregnancy: report on 69 cases","volume":"104","author":"Djelmis","year":"2002","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib16","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1136\/jnnp.40.11.1060","article-title":"Acetylcholinesterase activity and menstrual remissions in myasthenia gravis","volume":"40","author":"Vijayan","year":"1977","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib17","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1002\/mus.20734","article-title":"Single-fiber electromyography during menstrual exacerbation and ovulatory suppression in MuSK antibody-positive myasthenia gravis","volume":"35","author":"Stickler","year":"2007","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib18","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1001\/archneur.1964.00460240045006","article-title":"Treatment of myasthenia gravis by ovulatory suppression","volume":"11","author":"Frenkel","year":"1964","journal-title":"Arch Neurol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib19","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1046\/j.1468-1331.2000.00042.x","article-title":"Effects of sex hormones on experimental autoimmune myasthenia gravis","volume":"7","author":"Leker","year":"2000","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib20","doi-asserted-by":"crossref","first-page":"5050","DOI":"10.4049\/jimmunol.175.8.5050","article-title":"Estrogen enhances susceptibility to experimental autoimmune myasthenia gravis by promoting type 1-polarized immune responses","volume":"175","author":"Delpy","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib21","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0165-5728(94)90030-2","article-title":"Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice","volume":"53","author":"Jansson","year":"1994","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib22","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.4049\/jimmunol.173.4.2435","article-title":"Estrogen receptor alpha signaling in inflammatory leukocytes is dispensable for 17beta-estradiol-mediated inhibition of experimental autoimmune encephalomyelitis","volume":"173","author":"Garidou","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib23","first-page":"107","article-title":"Premature ovarian failure and ovarian autoimmunity","volume":"18","author":"Hoek","year":"1997","journal-title":"Endocr Rev"},{"key":"10.1016\/j.fertnstert.2007.07.1387_bib24","first-page":"321","article-title":"Immunological diseases in pregnancy","volume":"23","author":"Scott","year":"1977","journal-title":"Prog Allergy"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028207030440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028207030440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:27:12Z","timestamp":1758007632000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028207030440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["S0015028207030440"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2007.07.1387","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assisted reproduction treatment in severe myasthenia gravis","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2007.07.1387","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}