{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T08:02:23Z","timestamp":1771488143600,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":4925,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1016\/j.fertnstert.2007.10.063","type":"journal-article","created":{"date-parts":[[2008,2,6]],"date-time":"2008-02-06T08:44:33Z","timestamp":1202287473000},"page":"2068-2072","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Early serum interleukin-8 evaluation may prove useful in localizing abnormally implanted human gestations after in vitro fertilization"],"prefix":"10.1016","volume":"90","author":[{"given":"Sara S.","family":"Morelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debbra A.","family":"Keegan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis C.","family":"Krey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Noyes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2007.10.063_bib1","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/j.fertnstert.2004.01.017","article-title":"Assisted Reproductive Technology in the United States: 2000 results generated from the American Society for Reproductive Medicine\/Society for Assisted Reproductive Technology Registry","volume":"81","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib2","first-page":"73","article-title":"Surveillance for ectopic pregnancy\u2014United States, 1970\u20131989","volume":"42","author":"Goldner","year":"1993","journal-title":"MMWR CDC Surveill Summ"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib3","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/S0015-0282(99)00417-3","article-title":"Levels of vascular endothelial growth factor are elevated in patients with ectopic pregnancy: is this a novel marker?","volume":"72","author":"Daniel","year":"1999","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib4","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1093\/humrep\/dei218","article-title":"The value of a single combined measurement of VEGF, glycodelin, progesterone, PAPP-A, HPL and LIF for differentiating between ectopic and abnormal intrauterine pregnancy","volume":"20","author":"Daponte","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.fertnstert.2003.12.043","article-title":"Maternal serum vascular endothelial growth factor levels in early ectopic and intrauterine pregnancies after in vitro fertilization treatment","volume":"82","author":"Fasouliotis","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib6","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.fertnstert.2003.08.049","article-title":"Novel placental and nonplacental serum markers in ectopic versus normal intrauterine pregnancy","volume":"81","author":"Mueller","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib7","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1016\/S0143-4004(03)00134-6","article-title":"The chemokine connection: hormonal and embryonic regulation at the human maternal\u2013embryonic interface\u2014a review","volume":"24","author":"Dominguez","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib8","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/0167-5699(91)90120-I","article-title":"Human Th1 and Th2 subsets: doubt no more","volume":"12","author":"Romagnani","year":"1991","journal-title":"Immunol Today"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib9","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0167-5699(96)80606-2","article-title":"The expanding universe of T cells subsets: Th1, Th2 and more","volume":"17","author":"Mosmann","year":"1996","journal-title":"Immunol Today"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib10","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0165-0378(00)00060-7","article-title":"Cytokine network at the feto-maternal interface","volume":"47","author":"Saito","year":"2000","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib11","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0015-0282(99)00457-4","article-title":"The role of T-helper cytokines in human reproduction","volume":"73","author":"Lim","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib12","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/S0015-0282(00)00517-3","article-title":"Evidence of a Th1 type response associated with recurrent miscarriage","volume":"73","author":"Jenkins","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib13","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1001\/jama.1995.03520480053039","article-title":"T-helper 1 type immunity to trophoblast in women with recurrent spontaneous abortion","volume":"273","author":"Hill","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib14","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1365-2249.1996.d01-809.x","article-title":"Characterization of type 1 and type 2 cytokine production profile in physiologic and pathologic human pregnancy","volume":"106","author":"Marzi","year":"1996","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib15","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1093\/humrep\/15.9.2011","article-title":"Circulating cytokines and CD30 in normal human pregnancy and recurrent spontaneous abortions","volume":"15","author":"Makhseed","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib16","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0165-0378(97)00036-3","article-title":"Can Th1-like immune responses explain the immunopathology of recurrent spontaneous miscarriage?","volume":"35","author":"Haynes","year":"1997","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib17","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/j.1600-0897.1997.tb00218.x","article-title":"Modulations of cytokine expression in pregnant women","volume":"37","author":"Tranchot-Diallo","year":"1997","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib18","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/S0015-0282(02)04853-7","article-title":"Serum concentrations of interleukin-2R (IL-2R), IL-6, IL-8, and tumor necrosis factor alpha in patients with ectopic pregnancy","volume":"79","author":"Soriano","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/clinchem\/47.2.308","article-title":"Utility of commonly used commercial human chorionic gonadotropin immunoassays in the diagnosis and management of trophoblastic diseases","volume":"47","author":"Cole","year":"2001","journal-title":"Clin Chem"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib20","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.placenta.2007.01.011","article-title":"Hyperglycosylated hCG","volume":"28","author":"Cole","year":"2007","journal-title":"Placenta"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib21","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S0301-2115(01)00289-5","article-title":"Detection of interleukin-6, interleukin-8, and interleukin-11 in plasma from women with spontaneous abortion","volume":"98","author":"Koumantaki","year":"2001","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib22","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1093\/humrep\/17.1.219","article-title":"Interleukin-2 receptor concentrations in pregnant women with a history of recurrent miscarriage","volume":"17","author":"MacLean","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib23","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0015-0282(01)02002-7","article-title":"Maternal serum levels of tumor necrosis factor-\u03b1 and interleukin-2 receptor in threatened abortion: a comparison with normal and pathologic pregnancies","volume":"76","author":"Gucer","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib24","series-title":"Principles and practice of medical therapy in pregnancy","first-page":"511","article-title":"Alloimmunity and pregnancy loss","author":"Clark","year":"1998"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib25","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1093\/humrep\/deh169","article-title":"Maternal serum levels of interferon-gamma and interleukin-2 soluble receptor-alpha predict the outcome of early IVF pregnancies","volume":"19","author":"Fasouliotis","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib26","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4049\/jimmunol.155.1.128","article-title":"Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established T cell clones","volume":"155","author":"Piccinni","year":"1995","journal-title":"J Immunol"},{"key":"10.1016\/j.fertnstert.2007.10.063_bib27","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1600-0897.2007.00488.x","article-title":"Redirection of cytokine production by lymphocytes from women with preterm delivery by dydrogesterone","volume":"58","author":"Raghupathy","year":"2007","journal-title":"Am J Reprod Immunol"},{"issue":"Suppl 1","key":"10.1016\/j.fertnstert.2007.10.063_bib28","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1093\/humrep\/15.suppl_1.46","article-title":"Progesterone inhibits in vitro embryotoxic Th1 cytokine production to trophoblast in women with recurrent pregnancy loss","volume":"15","author":"Choi","year":"2000","journal-title":"Hum Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028207039490?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028207039490?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:27:54Z","timestamp":1758007674000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028207039490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S0015028207039490"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2007.10.063","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early serum interleukin-8 evaluation may prove useful in localizing abnormally implanted human gestations after in vitro fertilization","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2007.10.063","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}