{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T01:47:09Z","timestamp":1777340829037,"version":"3.51.4"},"reference-count":29,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":4955,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.fertnstert.2008.01.017","type":"journal-article","created":{"date-parts":[[2008,6,28]],"date-time":"2008-06-28T04:33:02Z","timestamp":1214627582000},"page":"2005.e7-2005.e10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Cervical ectopic pregnancy successfully treated with local methotrexate injection"],"prefix":"10.1016","volume":"90","author":[{"given":"Isabel","family":"Cerveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lourdes","family":"Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Cabral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2008.01.017_bib1","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/0002-9378(69)90075-1","article-title":"Cervical pregnancy as a possible sequel of induced abortion","volume":"105","author":"Shinagawa","year":"1969","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib2","first-page":"79","article-title":"Cervical pregnancy analysis: a review and report of five cases","volume":"62","author":"Parente","year":"1983","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib3","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1148\/radiology.191.3.8184062","article-title":"Cervical ectopic pregnancy: results of conservative treatment","volume":"191","author":"Frates","year":"1994","journal-title":"Radiology"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib4","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1001\/archfami.9.1.72","article-title":"Cervical ectopic pregnancy: diagnosis with endovaginal ultrasound examination and successful treatment with methotrexate","volume":"9","author":"Leeman","year":"2000","journal-title":"Arch Fam Med"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib5","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S0002-9378(45)90307-3","article-title":"Cervical pregnancy: a partial review of the literature and a report of two probable cases","volume":"49","author":"Studdiford","year":"1945","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib6","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/0002-9610(46)90387-X","article-title":"Distal ectopic pregnancy","volume":"72","author":"Schneider","year":"1946","journal-title":"Am J Surg"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib7","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00007611-195011000-00012","article-title":"Cervical Pregnancy","volume":"43","author":"Ellingson","year":"1950","journal-title":"Southern Medical Journal"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib8","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1479-828X.1968.tb00700.x","article-title":"Recent Investigations Concerning the Aetiology of Ectopic Pregnancies","volume":"8","author":"Iffy","year":"1968","journal-title":"The Australian and New Zealand Journal of Obstetrics and Gynaecology"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib9","first-page":"675","article-title":"Cervical pregnancy","volume":"42","author":"Rothe","year":"1973","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib10","first-page":"25","article-title":"Etiology of cervical pregnancy","volume":"30","author":"Dicker","year":"1985","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib11","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/S0015-0282(16)56714-4","article-title":"Early diagnosis and treatment of cervical pregnancy in an in vitro fertilization program","volume":"61","author":"Ginsburg","year":"1994","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib12","first-page":"1145","article-title":"Cervical pregnancy after in vitro fertilization and embryo transfer","volume":"161","author":"Weyerman","year":"1989","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib13","first-page":"241","article-title":"Cervical pregnancy managed without hysterectomy. A case report","volume":"34","author":"Nolan","year":"1989","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib14","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/0002-9378(90)90404-U","article-title":"Conservative management of cervical pregnancy with subsequent fertility","volume":"162","author":"Bachus","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib15","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/humrep\/17.2.493","article-title":"Cervical Shirodkar cerclage may be the treatment modality of choice for cervical pregnancy","volume":"17","author":"Mashiach","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib16","doi-asserted-by":"crossref","first-page":"801","DOI":"10.3346\/jkms.2001.16.6.801","article-title":"Preoperative uterine artery embolization and evacuation in the management of cervical pregnancy. Report of two cases","volume":"16","author":"Ryu","year":"2001","journal-title":"J Korean Med Sci"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib17","first-page":"938","article-title":"Preoperative angiographic uterine artery embolization in the management of cervical pregnancy","volume":"76","author":"Lobel","year":"1990","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib18","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1093\/humrep\/12.4.860","article-title":"Conservative treatment of cervical pregnancy by curettage and local prostaglandin injection","volume":"12","author":"Spitzer","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib19","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S1074-3804(05)60419-7","article-title":"Hysteroscopic resection of a cervical ectopic pregnancy","volume":"9","author":"Hardy","year":"2002","journal-title":"J Am Assoc Gynecol Laparosc"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib20","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0015-0282(16)58649-X","article-title":"Hysteroscopic resection of a cervical ectopic pregnancy","volume":"66","author":"Ash","year":"1996","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib21","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S1074-3804(05)60302-7","article-title":"Combination of laparoscopic bilateral uterine artery ligation and intraamniotic methotrexate injection for conservative management of cervical pregnancy","volume":"10","author":"Lin","year":"2003","journal-title":"J Am Assoc Gynecol Laparosc"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib22","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0002-9378(79)90878-0","article-title":"Bilateral internal iliac artery ligation in cervical pregnancy: conservation of reproductive function","volume":"134","author":"Nelson","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib23","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0028-2243(95)02039-U","article-title":"Successful treatment of a cervical pregnancy with a single low dose methotrexate regimen","volume":"60","author":"Dotters","year":"1995","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib24","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0002-9378(94)70273-X","article-title":"Successful management of viable cervical pregnancy by local injection of methotrexate guided by transvaginal ultrasonography","volume":"170","author":"Timor-Tritsch","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib25","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/j.1471-0528.1993.tb15279.x","article-title":"Advanced cervical pregnancy treated with actinomycin-D","volume":"100","author":"Brand","year":"1993","journal-title":"Br J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib26","first-page":"945","article-title":"Successful treatment of cervical pregnancy with oral etoposide","volume":"76","author":"Segna","year":"1990","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib27","first-page":"91","article-title":"Cervical pregnancy treated with methotrexate","volume":"44","author":"Farabow","year":"1983","journal-title":"N C Med J"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib28","doi-asserted-by":"crossref","first-page":"3239","DOI":"10.1093\/humrep\/13.11.3239","article-title":"Randomized trial of conservative laparoscopic treatment and methotrexate administration in ectopic pregnancy and subsequent fertility","volume":"13","author":"Fernandez","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.01.017_bib29","doi-asserted-by":"crossref","first-page":"263642","DOI":"10.1093\/humrep\/13.9.2636","article-title":"Prognostic factors for an unsatisfactory primary methotrexate treatment of cervical pregnancy: a quantitative review","volume":"13","author":"Hung","year":"1998","journal-title":"Hum Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028208000113?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028208000113?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:31:29Z","timestamp":1758007889000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028208000113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S0015028208000113"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2008.01.017","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cervical ectopic pregnancy successfully treated with local methotrexate injection","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2008.01.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}