{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:03:43Z","timestamp":1790352223093,"version":"4.1.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":4955,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004396","name":"Thailand Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004396","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.fertnstert.2008.01.019","type":"journal-article","created":{"date-parts":[[2008,3,11]],"date-time":"2008-03-11T09:17:11Z","timestamp":1205227031000},"page":"2015.e11-2015.e15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Identification of mutations in the SRD5A2 gene in Thai patients with male pseudohermaphroditism"],"prefix":"10.1016","volume":"90","author":[{"given":"Taninee","family":"Sahakitrungruang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suttipong","family":"Wacharasindhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patra","family":"Yeetong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiti","family":"Snabboon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanya","family":"Suphapeetiporn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vorasuk","family":"Shotelersuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2008.01.019_bib1","first-page":"577","article-title":"Steroid 5 alpha-reductase 2 deficiency","volume":"14","author":"Wilson","year":"1993","journal-title":"Endo Rev"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/(SICI)1096-8628(19960503)63:1<223::AID-AJMG39>3.0.CO;2-O","article-title":"Phenotypic classification of male pseudohermaphroditism due to steroid 5 alpha-reductase 2 deficiency","volume":"63","author":"Sinnecker","year":"1996","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib3","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1172\/JCI115954","article-title":"Molecular genetics of steroid 5 alpha-reductase 2 deficiency","volume":"90","author":"Thigpen","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib4","first-page":"2821","article-title":"Clinical, biochemical, and genetic findings in a large pedigree of male and female patients with 5 alpha-reductase 2 deficiency","volume":"81","author":"Hochberg","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib5","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1046\/j.1365-2265.2000.00941.x","article-title":"Identification of missense mutations in the SRD5A2 gene from patients with steroid 5alpha-reductase 2 deficiency","volume":"52","author":"Vilchis","year":"2000","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib6","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1126\/science.186.4170.1213","article-title":"Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism","volume":"186","author":"Imperato-McGinley","year":"1974","journal-title":"Science"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib7","first-page":"1240","article-title":"Phenotypic variation in a family with partial androgen insensitivity syndrome explained by differences in 5alpha dihydrotestosterone availability","volume":"86","author":"Boehmer","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib8","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1097\/01.ju.0000047621.66463.29","article-title":"Giant seminoma in a patient with 5 alpha-reductase type 2 deficiency","volume":"169","author":"Sasaki","year":"2003","journal-title":"J Urol"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib9","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1365-2265.1997.800904.x","article-title":"Mutations of the 5 alpha-reductase type 2 gene in eight Mexican patients from six different pedigrees with 5 alpha-reductase-2 deficiency","volume":"46","author":"Canto","year":"1997","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib10","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1021\/bi00171a029","article-title":"Natural mutagenesis study of the human steroid 5 alpha-reductase 2 isozyme","volume":"33","author":"Wigley","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib11","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1097\/00005792-199603000-00003","article-title":"Male pseudohermaphroditism due to steroid 5alpha-reductase 2 deficiency. Diagnosis, psychological evaluation, and management","volume":"75","author":"Mendonca","year":"1996","journal-title":"Medicine"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib12","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/(SICI)1096-8628(19991126)87:3<221::AID-AJMG5>3.0.CO;2-#","article-title":"New frameshift mutation in the 5alpha-reductase type 2 gene in a Brazilian patient with 5alpha-reductase deficiency","volume":"87","author":"Ferraz","year":"1999","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib13","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s00109-005-0651-7","article-title":"New mutations, hotspots, and founder effects in Brazilian patients with steroid 5alpha-reductase deficiency type 2","volume":"83","author":"Hackel","year":"2005","journal-title":"J Mol Med"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib14","first-page":"1730","article-title":"5 alpha-reductase-2 gene mutations in the Dominican Republic","volume":"81","author":"Cai","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib15","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1136\/adc.67.6.720","article-title":"Early diagnosis and management of 5 alpha-reductase deficiency","volume":"67","author":"Odame","year":"1992","journal-title":"Arch Dis Childhood"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib16","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/j.1939-4640.2004.tb02808.x","article-title":"Compound heterozygous mutations in the SRD5A2 gene exon 4 in a male pseudohermaphrodite patient of Chinese origin","volume":"25","author":"Fernandez-Cancio","year":"2004","journal-title":"J Androl"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib17","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000081893","article-title":"Clinical, biochemical and morphologic diagnostic markers in an infant male pseudohermaphrodite patient with compound heterozygous mutations (G115D\/R246W) in SRD5A2 gene","volume":"62","author":"Fernandez-Cancio","year":"2004","journal-title":"Hormone Res"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib18","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1210\/jcem-63-5-1091","article-title":"Characterization of the testicular abnormality in 5 alpha-reductase deficiency","volume":"63","author":"Johnson","year":"1986","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib19","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1093\/humrep\/14.1.136","article-title":"Reversion of the differentiated phenotype and maturation block in Sertoli cells in pathological human testis","volume":"14","author":"Steger","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib20","first-page":"3236","article-title":"Molecular characterization of 5 alpha-reductase type 2 deficiency and fertility in a Swedish family","volume":"83","author":"Nordenskjold","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2008.01.019_bib21","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1136\/adc.2006.098319","article-title":"Consensus statement on management of intersex disorders","volume":"91","author":"Hughes","year":"2006","journal-title":"Arch Dis Childhood"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028208000137?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028208000137?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:28:17Z","timestamp":1758007697000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028208000137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S0015028208000137"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2008.01.019","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of mutations in the SRD5A2 gene in Thai patients with male pseudohermaphroditism","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2008.01.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}