{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:11:46Z","timestamp":1771463506717,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":4498,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.fertnstert.2008.10.063","type":"journal-article","created":{"date-parts":[[2008,12,26]],"date-time":"2008-12-26T04:25:28Z","timestamp":1230265528000},"page":"833-836","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Absence of chlamydial deoxyribonucleic acid from testicular and epididymal samples from men with obstructive azoospermia"],"prefix":"10.1016","volume":"93","author":[{"given":"Sreebala","family":"Sripada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Rosario","family":"Amezaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Hamilton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamish","family":"McKenzie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan","family":"Templeton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siladitya","family":"Bhattacharya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2008.10.063_bib1","first-page":"1","article-title":"Towards more objectivity in diagnosis and management of male infertility","volume":"7","year":"1997","journal-title":"Int J Androl"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib2","series-title":"Male reproductive health and dysfunction","author":"Neischlag","year":"1997"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib3","series-title":"Biological components of fertility","first-page":"15","article-title":"The prevalence and aetiology of infertility","volume":"Vol. 1","author":"Farley","year":"1988"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib4","unstructured":"Health Protection Agency. Chlamydia. Available at:http:\/\/www.hpa.org.uk\/webw\/HPAweb&HPAwebStandard\/HPAweb_C\/1195733787092?p=1192454969657. Last accessed 1 November, 2008."},{"key":"10.1016\/j.fertnstert.2008.10.063_bib5","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S0022-5347(17)56978-5","article-title":"Etiology, manifestations and therapy of acute epididymitis: prospective study of 50 cases","volume":"121","author":"Berger","year":"1979","journal-title":"J Urol"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0094-0143(21)00745-X","article-title":"Nongonococcal urethritis","volume":"11","author":"Bowie","year":"1984","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib7","first-page":"31","article-title":"The impact of infection on sperm quality","volume":"1","author":"Purvis","year":"1995","journal-title":"J Br Fertil Soc"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0002-9378(94)70084-2","article-title":"Detection of Chlamydia trachomatis in fallopian tube tissue in women with postinfectious tubal infertility","volume":"171","author":"Patton","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib9","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0002-9378(94)70085-0","article-title":"Detection of Chlamydia trachomatis deoxyribonucleic acid in monkey models (Macaca nemestrina) of salpingitis by in situ hybridization: implications for pathogenesis","volume":"171","author":"Cappuccio","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib10","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1080\/014850199263039","article-title":"Chlamydia trachomatis detected by ligase chain reaction in the semen of asymptomatic patients without pyospermia or pyuria","volume":"42","author":"Fujisawa","year":"1999","journal-title":"Arch Androl"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib11","doi-asserted-by":"crossref","first-page":"3120","DOI":"10.1128\/jcm.34.12.3120-3128.1996","article-title":"Prokaryotic DNA sequences in patients with chronic idiopathic prostatitis","volume":"34","author":"Krieger","year":"1996","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib12","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S0015-0282(03)00396-0","article-title":"Immunopathogenesis of chlamydia trachomatis infections in women","volume":"79","author":"Debattista","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib13","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.8755-8920.2000.430406.x","article-title":"Detection of chlamydial antigenic material in ovarian, prostatic, ectopic pregnancy and semen samples of culture-negative subjects","volume":"43","author":"Toth","year":"2000","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib14","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1093\/humrep\/12.5.987","article-title":"Semen parameters in a fertile versus subfertile population: a need for change in the interpretation of semen testing","volume":"12","author":"Ombelet","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib15","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1128\/IAI.72.7.4210-4216.2004","article-title":"New murine model for the study of Chlamydia trachomatis genitourinary tract infections in males","volume":"72","author":"Pal","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib16","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1439-0272.2003.tb00866.x","article-title":"Inflammatory-associated obstructions of the male reproductive tract","volume":"35","author":"Dohle","year":"2003","journal-title":"Andrologia"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib17","first-page":"354","article-title":"Chlamydia prevalence in the United Kingdom: a systematic review and analysis of prevalence studies","volume":"80","author":"Adams","year":"2004","journal-title":"STI"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib18","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1128\/JCM.39.11.3915-3919.2001","article-title":"Characterization of Chlamydia trachomatis omp1 genotypes among sexually transmitted disease patients in Sweden","volume":"39","author":"Jurstrand","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib19","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1093\/humrep\/17.3.726","article-title":"Seminal antibodies to human 60kd heat shock protein (HSP 60) in male partners of subfertile couples","volume":"17","author":"Eggert-Kruse","year":"2002","journal-title":"Hum Reprod"},{"issue":"352","key":"10.1016\/j.fertnstert.2008.10.063_bib20","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/S0140-6736(97)10514-1","article-title":"Relation between semen quality and fertility: a population-based study of 430 first-pregnancy planners","volume":"10","author":"Bonde","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib21","first-page":"314","article-title":"Acrosome reaction in Chlamydia-positive and negative patients","volume":"35","author":"Jungwirth","year":"2003","journal-title":"Andrologia"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib22","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1093\/humrep\/deh155","article-title":"Demonstration of Chlamydia trachomatis IgG antibodies in the male partner of the infertile couple is correlated with a reduced likelihood of achieving pregnancy","volume":"19","author":"Idahl","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib23","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1017\/S0950268804002195","article-title":"Association between Chlamydia trachomatis antibodies and subfertility in the Northern Finland Birth Cohort 1966 (NFBC 1966), at the age of 31 years","volume":"132","author":"Karinen","year":"2004","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib24","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1365-2605.2006.00718.x","article-title":"Male serum Chlamydia trachomatis IgA and IgG, but not heat shock protein 60 IgG, correlates with negatively affected semen characteristics and lower pregnancy rates in the infertile couple","volume":"30","author":"Idahl","year":"2007","journal-title":"Int J Androl"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib25","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0015-0282(16)53290-7","article-title":"Male genital mycoplasmas and Chlamydia trachomatis culture: its relationship with accessory gland function, sperm quality, and autoimmunity","volume":"53","author":"Soffer","year":"1990","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib26","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF01717455","article-title":"Prevalence of genital chlamydia and mycoplasma infection in couples attending a male infertility clinic","volume":"10","author":"Samra","year":"1994","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib27","doi-asserted-by":"crossref","first-page":"2952","DOI":"10.1093\/oxfordjournals.humrep.a135827","article-title":"Relationship between an asymptomatic male genital tract exposure to Chlamydia trachomatis and an autoimmune response to spermatozoa","volume":"10","author":"Witkin","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib28","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/S0015-0282(16)54318-0","article-title":"Chlamydia trachomatis induces an inflammatory response in the male genital tract and is associated with altered semen quality","volume":"55","author":"Wolff","year":"1991","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib29","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/S0015-0282(16)59549-1","article-title":"The relationship of infection with Chlamydia trachomatis to the parameters of male fertility and sperm autoimmunity","volume":"48","author":"Close","year":"1987","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib30","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0015-0282(16)53581-X","article-title":"Chlamydial infection\u2014a female and\/or male infertility factor?","volume":"53","author":"Eggert-Kruse","year":"1990","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib31","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0015-0282(16)53228-2","article-title":"Is serology of any use when searching for correlations between Chlamydia trachomatis infection and male infertility?","volume":"53","author":"Ruijs","year":"1990","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib32","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1093\/oxfordjournals.humrep.a137707","article-title":"Chlamydial serology in the investigation of infertility","volume":"7","author":"Bjercke","year":"1992","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib33","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1439-0272.2002.00472.x","article-title":"Chlamydia trachomatis infection in male partners of infertile couples: incidence and sperm function","volume":"34","author":"Vigil","year":"2002","journal-title":"Andrologia"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib34","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/humrep\/16.2.293","article-title":"Co-incubation of human spermatozoa with Chlamydia trachomatis serovar E causes premature sperm death","volume":"16","author":"Hosseinzadeh","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2008.10.063_bib35","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1002\/j.1939-4640.2004.tb02764.x","article-title":"Semen quality of men with asymptomatic chlamydial infection","volume":"25","author":"Hosseinzadeh","year":"2004","journal-title":"J Androl"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820804418X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820804418X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:37:53Z","timestamp":1758008273000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001502820804418X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S001502820804418X"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2008.10.063","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Absence of chlamydial deoxyribonucleic acid from testicular and epididymal samples from men with obstructive azoospermia","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2008.10.063","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}