{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T09:20:35Z","timestamp":1781169635146,"version":"3.54.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T00:00:00Z","timestamp":1662940800000},"content-version":"vor","delay-in-days":4578,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.fertnstert.2009.02.021","type":"journal-article","created":{"date-parts":[[2009,3,23]],"date-time":"2009-03-23T10:28:05Z","timestamp":1237804085000},"page":"1643-1649","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Effects of metoclopramide-induced hyperprolactinemia on the prolactin receptor of murine endometrium"],"prefix":"10.1016","volume":"93","author":[{"given":"Alexandre Guilherme Zabeu","family":"Rossi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina C\u00e9lia","family":"Teixeira Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"de Jesus Sim\u00f5es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"dos Santos Sim\u00f5es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia B.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Jos\u00e9 Maria","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmund C.","family":"Baracat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2009.02.021_bib1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1365-2265.1975.tb01929.x","article-title":"Incidence and significance of hyperprolactinemia in women with amenorrhea","volume":"4","author":"Franks","year":"1975","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib2","first-page":"457","article-title":"Discordant patterns of hyperprolactinemia and galactorrhoea in secondary amenorrhea","volume":"86","author":"Seppala","year":"1977","journal-title":"Acta Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib3","series-title":"Ginecologia end\u00f3crina","first-page":"131","article-title":"Hiperprolactinemia","author":"Lengyel","year":"1995"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib4","series-title":"Guias de medicina ambulatorial e hospitalar\u2013UNIFESP\/escola paulista de medicina\u2014Ginecologia","first-page":"267","article-title":"Hiperprolactinemia","author":"Rossi","year":"2005"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib5","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0889-8529(18)30471-7","article-title":"Prolactinomas","volume":"16","author":"Vance","year":"1987","journal-title":"Endocrinol Met Clin N Am"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1159\/000068380","article-title":"Metoclopramide-induced hyperprolactinemia affects mouse endometrial morphology","volume":"54","author":"Rossi","year":"2002","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib7","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1093\/humrep\/del093","article-title":"Metoclopramide-induced hyperprolactinemia caused marked decline in pinopods and pregnancy rates in mice","volume":"21","author":"Panzan","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib8","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1210\/jcem-62-5-899","article-title":"Ovulation indution with bromocriptine in normoprolactinemic anovulatory women","volume":"62","author":"Suginami","year":"1986","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib9","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1126\/science.694535","article-title":"Prolactin syntesis by human chorion\u2013decidual tissue: a possible source of prolactin in the amniotic fluid","volume":"202","author":"Golander","year":"1978","journal-title":"Science"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib10","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/0002-9378(79)90386-7","article-title":"Prolactin production by human endometrium during the normal menstrual cycle","volume":"135","author":"Maslar","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib11","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1677\/jme.0.0140255","article-title":"The relationship between decidualisation and prolactin mRNA and production at different stages of human pregnancy","volume":"14","author":"Wu","year":"1995","journal-title":"J Mol Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib12","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1210\/jcem.83.1.4506","article-title":"Localization and temporal pattern of expression of prolactin receptor in human endometrium","volume":"83","author":"Jones","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib13","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1210\/jcem.83.7.4989","article-title":"Expression of funcional prolactin receptors in nonpregnant human endometrium: Janus kinase-2, signal transducer and activator of transcription-1 (STAT1), and STAT5 proteins are phosphorylated after stimulation with prolactin","volume":"83","author":"Jabbour","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib14","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1677\/JOE-08-0077","article-title":"Regulation of electrolyte transport across cultured endometrial epithelial cells by prolactin","volume":"197","author":"Deachapunya","year":"2008","journal-title":"J Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib15","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1095\/biolreprod62.6.1779","article-title":"Prolactin receptor and uterine milk protein expression in the ovine endometrium during the estrous cycle and pregnancy","volume":"62","author":"Stewart","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib16","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0020-7292(99)00228-3","article-title":"Endometrial prolactin in hyperprolactinemic women","volume":"69","author":"Arie","year":"2000","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib17","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1677\/jme.1.01702","article-title":"Differential effects of sex steroid hormones on the expression of multiple first exons including a novel first exon of prolactin receptor gene in the rat liver","volume":"34","author":"Tanaka","year":"2005","journal-title":"J Mol Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib18","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/0039-128X(91)90006-H","article-title":"Effects of sexual steroid hormones on the functionality of murine peritoneal macrophages","volume":"56","author":"Bara\u00f1ao","year":"1991","journal-title":"Steroids"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib19","doi-asserted-by":"crossref","first-page":"3564","DOI":"10.1210\/endo.141.10.7691","article-title":"Prolactin (PRL) receptor gene expression in mouse adipose tissue: increases during lactation and in PRL-transgenic mice","volume":"141","author":"Ling","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib20","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0024-3205(91)90004-U","article-title":"Development of uterine adenomyosis after treatment with dopamine antagonists in mice","volume":"49","author":"Singtripop","year":"1991","journal-title":"Life Sci"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib21","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1210\/en.2007-0867","article-title":"Hypothalamic prolactin receptor messenger ribonucleic acid levels, prolactin signaling, and hyperprolactinemic inhibition of pulsatile luteinizing hormone secretion are dependent on estradiol","volume":"149","author":"Anderson","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib22","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1210\/me.2006-0297","article-title":"Progesterone receptor repression of prolactin\/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells","volume":"21","author":"Buser","year":"2007","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib23","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1590\/S0004-27492006000500004","article-title":"Effects of metoclopramide-induced hyperprolactinemia on the murine corneal","volume":"69","author":"Verna","year":"2006","journal-title":"Arq Bras Oftalmol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib24","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000181930","article-title":"Effects of prolactin on cultured human endometrial cells","volume":"35","author":"Negami","year":"1991","journal-title":"Horm Res"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib25","doi-asserted-by":"crossref","first-page":"14263","DOI":"10.1074\/jbc.272.22.14263","article-title":"Steroidogenic factor-1 is an essential transcriptional activator for gonad-specific expression of promoter I of the rat prolactin receptor gene","volume":"272","author":"Hu","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib26","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1210\/endo-111-2-645","article-title":"On the primary site of action of estrogens and androgens in the regulation of hepatic prolactin receptors","volume":"111","author":"Norstedt","year":"1982","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1677\/joe.0.1610033","article-title":"Involvement of gonadal steroid hormone disturbance in altered prolactin receptor gene expression in the liver of diabetic mice","volume":"161","author":"Yasui","year":"1999","journal-title":"J Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib28","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1677\/joe.0.1430383","article-title":"Differential regulation of prolactin receptor mRNA expression in rat liver and kidney by testosterone and oestradiol","volume":"143","author":"Sakaguchi","year":"1994","journal-title":"J Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib29","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1210\/endo.141.5.7464","article-title":"Implantation and decidualization defects in prolactin receptor (PRLR)-deficient mice are mediated by ovarian but not uterine PRLR","volume":"141","author":"Reese","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib30","doi-asserted-by":"crossref","first-page":"4878","DOI":"10.1210\/endo.137.11.8895360","article-title":"The decidual prolactin receptor and its regulation by decidua-derived factors","volume":"137","author":"Gu","year":"1996","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib31","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1210\/endo.131.3.1380439","article-title":"Alpha 2-macroglobulin expression in the mesometrial decidua and its regulation by decidual luteotropin and prolactin","volume":"131","author":"Gu","year":"1992","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib32","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1095\/biolreprod.102.011684","article-title":"Decidual activin: its role in the apoptotic process and its regulation by prolactin","volume":"68","author":"Tessier","year":"2003","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib33","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0021-9258(19)75947-X","article-title":"Sequence of rat liver alpha 2-macroglobulin and acute phase control of its messenger RNA","volume":"262","author":"Gehring","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib34","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1210\/mend-5-9-1280","article-title":"Regulation of alpha 2-macroglobulin by luteinizing hormone and prolactin during cell differentiation in the rat ovary","volume":"5","author":"Gaddy-Kurten","year":"1991","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib35","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1677\/joe.0.1390235","article-title":"Rat placental lactogen-I binds to the choroid plexus and hypothalamus of the pregnant rat","volume":"139","author":"Freemark","year":"1993","journal-title":"J Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.021_bib36","first-page":"171","article-title":"Prolactin induction of the alpha 2-Macroglobulin gene in rat ovarian granulosa cells: stat 5 activation and binding to the interleukin-6 response element","volume":"10","author":"Dajee","year":"1996","journal-title":"Mol Endocrinol"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820900380X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502820900380X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:39:01Z","timestamp":1758008341000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001502820900380X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S001502820900380X"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2009.02.021","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of metoclopramide-induced hyperprolactinemia on the prolactin receptor of murine endometrium","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2009.02.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}