{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T06:10:58Z","timestamp":1762150258684,"version":"build-2065373602"},"reference-count":22,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T00:00:00Z","timestamp":1662940800000},"content-version":"vor","delay-in-days":4821,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1016\/j.fertnstert.2009.02.068","type":"journal-article","created":{"date-parts":[[2009,4,10]],"date-time":"2009-04-10T04:14:07Z","timestamp":1239336847000},"page":"390.e9-390.e11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["A novel sequence variation in the transactivation regulating domain of the human androgen receptor"],"prefix":"10.1016","volume":"92","author":[{"given":"Katja Anette","family":"Hose","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina","family":"H\u00e4ffner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Fietz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Gromoll","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Eckert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Kliesch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Christian","family":"Siebert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Bergmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2009.02.068_bib1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1159\/000076816","article-title":"The androgen receptor in spermatogenesis","volume":"103","author":"Collins","year":"2003","journal-title":"Cytogenet Genome Res"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib2","first-page":"264","article-title":"Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism","volume":"44","author":"Brown","year":"1989","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib3","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0006-291X(88)80591-6","article-title":"Identification of a new member of the steroid receptor super-family by cloning and sequence analysis","volume":"155","author":"Chang","year":"1988","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib4","doi-asserted-by":"crossref","first-page":"7211","DOI":"10.1073\/pnas.85.19.7211","article-title":"Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors","volume":"85","author":"Chang","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1126\/science.3353727","article-title":"Cloning of human androgen receptor complementary DNA and localization to the X chromosome","volume":"240","author":"Lubahn","year":"1988","journal-title":"Science"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib6","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.bi.63.070194.002315","article-title":"Molecular mechanisms of action of steroid\/thyroid receptor superfamily members","volume":"63","author":"Tsai","year":"1994","journal-title":"Ann Rev Biochem"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib7","series-title":"Testosterone, Action, Deficiency, Substitution","first-page":"33","article-title":"The androgen receptor: Physiology and pathophysiology","author":"Quigley","year":"1998"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib8","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1093\/hmg\/6.12.2005","article-title":"Rethinking genotype and phenotype correlations in polyglutamine expansion disorders","volume":"6","author":"Andrew","year":"1997","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib9","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/nar\/20.6.1427-a","article-title":"Trinucleotide repeat polymorphism in the androgen receptor gene (AR)","volume":"20","author":"Sleddens","year":"1992","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib10","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0960-0760(96)00097-0","article-title":"Transcriptional activation and transient expression of the human androgen receptor","volume":"59","author":"Gao","year":"1996","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib11","first-page":"3777","article-title":"Long polyglutamine tracts in the androgen receptor are associated with reduced transactivation, impaired sperm production, and male infertility","volume":"82","author":"Tut","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib12","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000182282","article-title":"Molecular analysis of the androgen receptor gene in 52 patients with complete or partial androgen insensitivity syndrome: a collaborative study","volume":"37","author":"Lobaccaro","year":"1992","journal-title":"Horm Res"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib13","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/(SICI)1096-8628(19990528)84:3<233::AID-AJMG14>3.0.CO;2-6","article-title":"Tissue heterogeneity of the FMR1 mutation in a high-functioning male with fragile X syndrome","volume":"84","author":"Taylor","year":"1999","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib14","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1086\/302578","article-title":"Tissue-specific somatic mosaicism in spinal and bulbar muscular atrophy is dependent on CAG-repeat length and androgen receptor-gene expression level","volume":"65","author":"Tanaka","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib15","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1002\/jcc.20290","article-title":"The Amber biomolecular simulation programs","volume":"26","author":"Case","year":"2005","journal-title":"J Comput Chem"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib16","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1365-2265.1994.tb02455.x","article-title":"Serum FSH and testicular morphology in male infertility","volume":"40","author":"Bergmann","year":"1994","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib17","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1530\/rep.0.1250769","article-title":"Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood","volume":"125","author":"Sharpe","year":"2003","journal-title":"Reproduction"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib18","doi-asserted-by":"crossref","first-page":"4614","DOI":"10.1128\/MCB.21.14.4614-4625.2001","article-title":"Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split","volume":"21","author":"Yu","year":"2001","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib19","doi-asserted-by":"crossref","first-page":"20229","DOI":"10.1074\/jbc.274.29.20229","article-title":"The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator","volume":"274","author":"Hsiao","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib20","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.1210\/jc.2007-1110","article-title":"Male infertility and variation in CAG repeat length in the androgen receptor gene: a meta-analysis","volume":"92","author":"Davis-Dao","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib21","first-page":"1590","article-title":"A novel mutation in the CAG triplet region of exon 1 of androgen receptor gene causes complete androgen insensitivity syndrome in a large kindred","volume":"84","author":"Zhu","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2009.02.068_bib22","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1016\/S0015-0282(03)00256-5","article-title":"A novel sequence variation in the transactivation regulating domain of the androgen receptor in two infertile Finnish men","volume":"79","author":"Lund","year":"2003","journal-title":"Fertil Steril"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028209004956?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028209004956?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T06:07:57Z","timestamp":1762150077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028209004956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["S0015028209004956"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2009.02.068","relation":{},"ISSN":["0015-0282"],"issn-type":[{"type":"print","value":"0015-0282"}],"subject":[],"published":{"date-parts":[[2009,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel sequence variation in the transactivation regulating domain of the human androgen receptor","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2009.02.068","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}