{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:07:12Z","timestamp":1758816432259,"version":"3.44.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":4348,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.fertnstert.2010.01.050","type":"journal-article","created":{"date-parts":[[2010,3,15]],"date-time":"2010-03-15T05:35:11Z","timestamp":1268631311000},"page":"753.e5-753.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["SRY-negative 46,XX infertile male with Leydig cell hyperplasia: clinical, cytogenetic, and molecular analysis and review of the literature"],"prefix":"10.1016","volume":"94","author":[{"given":"Ji Won","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong Won","family":"Bak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Uk","family":"Chin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Hyun","family":"Cha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae Ki","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Han","family":"Shim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2010.01.050_bib1","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/346240a0","article-title":"A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif","volume":"346","author":"Sinclair","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib2","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1093\/humrep\/16.4.717","article-title":"XX males without SRY gene and with infertility","volume":"16","author":"Abusheikha","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib3","doi-asserted-by":"crossref","first-page":"501","DOI":"10.2214\/ajr.180.2.1800501","article-title":"Testicular Leydig's cell hyperplasia: MR imaging and sonographic findings","volume":"180","author":"Carucci","year":"2003","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib4","first-page":"139","article-title":"Leydig cell tumor and hyperplasia: a review","volume":"29","author":"Colecchia","year":"2007","journal-title":"Anal Quant Cytol Histol"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib5","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000096236","article-title":"Extended pedigree with multiple cases of XX sex reversal in the absence of SRY and of a mutation at the SOX9 locus","volume":"1","author":"Temel","year":"2007","journal-title":"Sex Dev"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib6","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.urology.2008.09.050","article-title":"46, XX SRY-negative true hermaphrodite siblings","volume":"73","author":"Dorsey","year":"2009","journal-title":"Urology"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib7","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.fertnstert.2004.06.055","article-title":"46, XX SRY-negative man with complete virilization and infertility as the main anomaly","volume":"83","author":"Valetto","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib8","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S1472-6483(10)60807-3","article-title":"Azoospermia factor (AZF) in Yq11: towards a molecular understanding of its function for human male fertility and spermatogenesis","volume":"10","author":"Vogt","year":"2005","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib9","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/molehr\/gal030","article-title":"SRY-negative 46, XX male with normal genitals, complete masculinization and infertility","volume":"12","author":"Rajender","year":"2006","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/ng1141","article-title":"Dax1 is required for testis determination","volume":"34","author":"Meeks","year":"2003","journal-title":"Nat Genet"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib11","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1242\/dev.122.9.2813","article-title":"A male-specific role for SOX9 in vertebrate sex determination","volume":"122","author":"Kent","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib12","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1210\/jc.2007-1115","article-title":"XX maleness and XX true hermaphroditism in SRY-negative monozygotic twins: additional evidence for a common origin","volume":"93","author":"Maciel-Guerra","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib13","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0090-4295(91)80100-L","article-title":"Non-germ cell tumors of testis","volume":"37","author":"Dilworth","year":"1991","journal-title":"Urology"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib14","first-page":"164","article-title":"Leydig cell hyperplasia revealed by gynecomastia","volume":"10","author":"Tazi","year":"2008","journal-title":"Rev Urol"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib15","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1046\/j.1464-410X.1998.00503.x","article-title":"Leydig cell hyperplasia","volume":"81","author":"Naughton","year":"1998","journal-title":"Br J Urol"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib16","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/1096-8628(20000828)93:5<417::AID-AJMG13>3.0.CO;2-S","article-title":"Partially deleted SRY gene confined to testicular tissue in a 46, XX true hermaphrodite without SRY in leukocytic DNA","volume":"93","author":"Jimenez","year":"2000","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1034\/j.1399-0004.2000.570109.x","article-title":"An SRY-negative XX male with Huriez syndrome","volume":"57","author":"Vernole","year":"2000","journal-title":"Clin Genet"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib18","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1159\/000030262","article-title":"Detection of the sex-determining region of the Y chromosome in 46, XX true hermaphroditism","volume":"60","author":"Kojima","year":"1998","journal-title":"Urol Int"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib19","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1007\/s004390050561","article-title":"Two SRY-negative XX male brothers without genital ambiguity","volume":"100","author":"Zenteno","year":"1997","journal-title":"Hum Genet"},{"key":"10.1016\/j.fertnstert.2010.01.050_bib20","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1007\/BF02281867","article-title":"SRY-negative true hermaphrodites and an XX male in two generations of the same family","volume":"97","author":"Ramos","year":"1996","journal-title":"Hum Genet"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028210001251?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028210001251?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:45:25Z","timestamp":1758008725000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028210001251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0015028210001251"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2010.01.050","relation":{},"ISSN":["0015-0282"],"issn-type":[{"type":"print","value":"0015-0282"}],"subject":[],"published":{"date-parts":[[2010,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SRY-negative 46,XX infertile male with Leydig cell hyperplasia: clinical, cytogenetic, and molecular analysis and review of the literature","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2010.01.050","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}