{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T02:08:43Z","timestamp":1767838123504,"version":"3.49.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:00:00Z","timestamp":1682294400000},"content-version":"vor","delay-in-days":4437,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1016\/j.fertnstert.2010.10.022","type":"journal-article","created":{"date-parts":[[2010,11,12]],"date-time":"2010-11-12T04:24:13Z","timestamp":1289535853000},"page":"1005-1012","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Testicular sperm from patients with obstructive and nonobstructive azoospermia: aneuploidy risk and reproductive prognosis using testicular sperm from fertile donors as control samples"],"prefix":"10.1016","volume":"95","author":[{"given":"Lorena","family":"Rodrigo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Rubio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Peinado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Villam\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasser","family":"Al-Asmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Remoh\u00ed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Pellicer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Sim\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Gil-Salom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2010.10.022_bib1","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.1093\/oxfordjournals.humrep.a135880","article-title":"Efficacy of intracytoplasmic sperm injection using testicular spermatozoa","volume":"10","author":"Gil-Salom","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib2","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1093\/humrep\/dep035","article-title":"Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE: the European IVF Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE)","volume":"24","author":"Nyboe Andersen","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib3","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1016\/S0022-5347(01)66698-9","article-title":"Intracytoplasmic testicular sperm injection: an effective treatment for otherwise intractable obstructive azoospermia","volume":"154","author":"Gil-Salom","year":"1995","journal-title":"J Urol"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib4","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1016\/S0022-5347(01)62243-2","article-title":"Testicular sperm extraction and intracytoplasmic sperm injection: a chance of fertility in nonobstructive azoospermia","volume":"160","author":"Gil-Salom","year":"1998","journal-title":"J Urol"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib5","doi-asserted-by":"crossref","first-page":"73","DOI":"10.4103\/0974-1208.44114","article-title":"The outcome of assisted reproductive technology in males with impaired spermatogenesis","volume":"1","author":"Mangoli","year":"2008","journal-title":"J Hum Reprod Sci"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib6","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/humrep\/14.3.741","article-title":"Fertilization and pregnancy outcome with intracytoplasmic sperm injection for azoospermic men","volume":"14","author":"Palermo","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib7","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0015-0282(02)04809-4","article-title":"Intracytoplasmic sperm injection with testicular spermatozoa is less successful in men with nonobstructive azoospermia than in men with obstructive azoospermia","volume":"79","author":"Vernaeve","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib8","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1093\/humrep\/17.10.2600","article-title":"Prenatal testing in ICSI pregnancies: incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters","volume":"17","author":"Bonduelle","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib9","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1093\/humrep\/deg403","article-title":"Pregnancy outcome and neonatal data of children born after ICSI using testicular sperm in obstructive and nonobstructive azoospermia","volume":"18","author":"Vernaeve","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib10","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.fertnstert.2004.02.110","article-title":"Prenatal karyotypes of fetuses conceived by intracytoplasmic sperm injection","volume":"82","author":"Jozwiak","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib11","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1093\/humrep\/14.5.1151","article-title":"Meiotic aneuploidy in the XXY mouse: evidence that a compromised testicular environment increases the incidence of meiotic error","volume":"14","author":"Mroz","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib12","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/humrep\/14.2.375","article-title":"Meiotic abnormalities and spermatogenic parameters in severe oligoasthenozoospermia","volume":"14","author":"Vendrell","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib13","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF00286660","article-title":"Meiotic studies in a series of 1100 infertile and sterile males","volume":"65","author":"Egozcue","year":"1983","journal-title":"Hum Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib14","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s004390050665","article-title":"Increased rate of nondisjunction in sex cells derived from low-quality semen","volume":"102","author":"Finkelstein","year":"1998","journal-title":"Hum Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib15","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1007\/s004390050751","article-title":"Assessment of autosome and gonosome disomy in human sperm nuclei by chromosome painting","volume":"102","author":"Rives","year":"1998","journal-title":"Hum Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib16","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1093\/hmg\/ddh302","article-title":"Defective recombination in infertile men","volume":"13","author":"Gonsalves","year":"2004","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib17","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1159\/000086913","article-title":"Immunofluorescent synaptonemal complex analysis in azoospermic men","volume":"111","author":"Sun","year":"2005","journal-title":"Cytogenet Genome Res"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib18","doi-asserted-by":"crossref","first-page":"2870","DOI":"10.1093\/hmg\/ddm246","article-title":"Abnormal meiotic recombination in infertile men and its association with sperm aneuploidy","volume":"16","author":"Ferguson","year":"2007","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib19","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/humrep\/den027","article-title":"The relationship between meiotic recombination in human spermatocytes and aneuploidy in sperm","volume":"23","author":"Sun","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib20","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/molehr\/gan030","article-title":"Reduced meiotic recombination on the XY bivalent is correlated with an increased incidence of sex chromosome aneuploidy in men with nonobstructive azoospermia","volume":"14","author":"Sun","year":"2008","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib21","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1093\/humrep\/15.10.2165","article-title":"Frequency of hyper-, hypohaploidy and diploidy in ejaculate, epididymal, and testicular germ cells of infertile patients","volume":"15","author":"Bernardini","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib22","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0015-0282(01)01957-4","article-title":"Sperm chromosome abnormalities in men with severe male factor infertility who are undergoing in vitro fertilization with intracytoplasmic sperm injection","volume":"76","author":"Levron","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib23","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/humrep\/17.3.570","article-title":"Chromosome analysis of epididymal and testicular sperm in azoospermic patients undergoing ICSI","volume":"17","author":"Palermo","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib24","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/sj.ejhg.5200814","article-title":"Chromosome analysis of epididymal and testicular spermatozoa in patients with azoospermia","volume":"10","author":"Burrello","year":"2002","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib25","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1093\/humrep\/17.9.2249","article-title":"FISH analysis of chromosome X, Y and 18 abnormalities in testicular sperm from azoospermic patients","volume":"17","author":"Mateizel","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib26","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/humrep\/deh012","article-title":"Analysis of chromosomal abnormalities in testicular and epididymal spermatozoa from azoospermic ICSI patients by fluorescence in-situ hybridization","volume":"19","author":"Rodrigo","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib27","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1093\/humrep\/16.10.2084","article-title":"Incidence of sperm chromosomal abnormalities in a risk population: relationship with sperm quality and ICSI outcome","volume":"16","author":"Rubio","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib28","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1093\/humrep\/dep037","article-title":"Prognostic value of sperm fluorescence in situ hybridizadion analysis over PGD","volume":"24","author":"S\u00e1nchez-Castro","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib29","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S1472-6483(10)60015-6","article-title":"Prognostic factors for preimplantation genetic screening in repeated pregnancy loss","volume":"18","author":"Rubio","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib30","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/j.fertnstert.2009.05.061","article-title":"Impact of different patterns of sperm chromosomal abnormalities on the chromosomal constitution of preimplantation embryos","volume":"94","author":"Rodrigo","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib31","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0015-0282(02)04407-2","article-title":"Chromosomal abnormalities in embryos derived from testicular sperm extraction","volume":"79","author":"Silber","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib32","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1093\/humrep\/deh306","article-title":"Comparison of the aneuploidy frequency in embryos derived from testicular sperm extraction in obstructive and nonobstructive azoospermic men","volume":"19","author":"Platteau","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib33","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S1472-6483(10)61146-7","article-title":"FISH screening of aneuploidies in preimplantation embryos to improve IVF outcome","volume":"11","author":"Rubio","year":"2005","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib34","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1369\/jhc.4B6434.2005","article-title":"Sperm and blastomere aneuploidy detection in reproductive genetics and medicine","volume":"53","author":"Gianaroli","year":"2005","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib35","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1093\/humrep\/del177","article-title":"Does PGD for aneuploidy screening change the selection of embryos derived from testicular sperm extraction in obstructive and nonobstructive azoospermic men?","volume":"21","author":"Donoso","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib36","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1093\/molehr\/5.7.682","article-title":"Preimplantation genetic diagnosis and sperm analysis by fluorescence in-situ hybridization for the most common reciprocal translocation t(11;22)","volume":"5","author":"Van Assche","year":"1999","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib37","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1530\/rep.0.1210655","article-title":"Aneuploidy in human spermatozoa: FISH analysis in men with constitutional chromosomal abnormalities, and in infertile men","volume":"121","author":"Shi","year":"2001","journal-title":"Reproduction"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib38","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/S0015-0282(03)00252-8","article-title":"Predictive value of sperm fluorescence in situ hybridization analysis on the outcome of preimplantation genetic diagnosis for translocations","volume":"79","author":"Escudero","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib39","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1093\/humrep\/deh817","article-title":"The high incidence of meiotic errors increases with decreased sperm count in severe male factor infertilities","volume":"20","author":"Pang","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib40","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1093\/humrep\/dem152","article-title":"Role of sperm FISH studies in the genetic reproductive advice of structural reorganization carriers","volume":"22","author":"Anton","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib41","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1016\/j.fertnstert.2008.12.139","article-title":"Role of sperm fluorescent in situ hybridization studies in infertile patients: indications, study approach, and clinical relevance","volume":"93","author":"Serrate","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib42","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.fertnstert.2005.04.048","article-title":"Comparison of the sperm aneuploidy rate in severe oligozoospermic and oligozoospermic men and its relation to intracytoplasmic sperm injection outcome","volume":"84","author":"Nagvenkar","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib43","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1093\/humrep\/dem395","article-title":"The role of sperm aneuploidy as a predictor of the success of intracytoplasmic sperm injection?","volume":"23","author":"Nicopoullos","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib44","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1093\/humrep\/14.5.1266","article-title":"Detection of aneuploidy for chromosomes 4, 6, 7, 8, 9, 10, 11, 12, 13, 17, 18, 21, X and Y by fluorescence in-situ hybridization in spermatozoa from nine patients with oligoasthenoteratozoospermia undergoing intracytoplasmic sperm injection","volume":"14","author":"Pang","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib45","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1093\/humrep\/dei033","article-title":"Frequency of aneuploidy in sperm from patients with extremely severe male factor infertility","volume":"20","author":"Gianaroli","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib46","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1093\/humrep\/12.9.1955","article-title":"The effect of follicle stimulating hormone therapy on human sperm structure (Notulae seminologicae 11)","volume":"12","author":"Baccetti","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib47","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/ng0398-251","article-title":"Testicular degeneration in Bclw-deficient mice","volume":"18","author":"Ross","year":"1998","journal-title":"Nat Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib48","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1530\/ror.0.0040038","article-title":"Hormonal and genetic control of germ cell apoptosis in the testes","volume":"4","author":"Sinha Hikim","year":"1999","journal-title":"Rev Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib49","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1095\/biolreprod57.5.1193","article-title":"Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation","volume":"57","author":"Sinha Hikim","year":"1997","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib50","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1093\/humrep\/dem376","article-title":"Gonadotrophins regulate germ cell survival, not proliferation, in normal adult men","volume":"23","author":"Ruwanpura","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib51","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1530\/ror.0.0040031","article-title":"Origin of DNA damage in ejaculated human spermatozoa","volume":"4","author":"Sakkas","year":"1999","journal-title":"Rev Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib52","doi-asserted-by":"crossref","first-page":"233","DOI":"10.14712\/fb2009055060233","article-title":"Morphometrical evaluation of germ cell apoptosis in infertile men","volume":"55","author":"Stiblar-Martincic","year":"2009","journal-title":"Folia Biol (Praha)"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib53","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1242\/jcs.114.16.2953","article-title":"Evidence for meiotic spindle checkpoint from analysis of spermatocytes from Robertsonian-chromosome heterozygous mice","volume":"114","author":"Eaker","year":"2001","journal-title":"J Cell Sci"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib54","doi-asserted-by":"crossref","first-page":"106","DOI":"10.2164\/jandrol.107.002998","article-title":"Morphology and meiotic segregation in spermatozoa from men of proven fertility","volume":"29","author":"Collodel","year":"2008","journal-title":"J Androl"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib55","doi-asserted-by":"crossref","first-page":"94","DOI":"10.2164\/jandrol.05081","article-title":"Studies on varicocele III: ultrastructural sperm evaluation and 18, X and Y aneuploidies","volume":"27","author":"Baccetti","year":"2006","journal-title":"J Androl"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib56","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1016\/S0015-0282(98)00058-2","article-title":"Interindividual variations in the disomy frequencies of human spermatozoa and their correlation with nuclear maturity as evaluated by aniline blue staining","volume":"69","author":"Morel","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib57","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1093\/humrep\/16.6.1209","article-title":"FISH assessment of aneuploidy frequencies in mature and immature human spermatozoa classified by the absence or presence of cytoplasmic retention","volume":"16","author":"Kovanci","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib58","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/aja.2008.31","article-title":"18, X, Y aneuploidies and transmission electron microscopy studies in spermatozoa from five carriers of different reciprocal translocations","volume":"11","author":"Moretti","year":"2009","journal-title":"Asian J Androl"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib59","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1016\/j.fertnstert.2009.05.033","article-title":"Double probing individual human spermatozoa: aniline blue staining for persistent histones and fluorescence in situ hybridization for aneuploidies","volume":"93","author":"Ov\u00e1ri","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib60","doi-asserted-by":"crossref","first-page":"38","DOI":"10.2164\/jandrol.106.000067","article-title":"Increased aneuploidy rate in sperm with fragmented DNA as determined by the sperm chromatin dispersion (SCD) test and FISH analysis","volume":"28","author":"Muriel","year":"2007","journal-title":"J Androl"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib61","first-page":"681","article-title":"Analysis of sperm chromosomal abnormalities and sperm DNA fragmentation in infertile males","volume":"25","author":"Qiu","year":"2008","journal-title":"Zhonghua Yi Xue Yi Chuan Xue Za Zhi"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib62","doi-asserted-by":"crossref","first-page":"e163","DOI":"10.1111\/j.1365-2605.2009.00982.x","article-title":"Aneuploidy and DNA fragmentation in morphologically abnormal sperm","volume":"33","author":"Tang","year":"2010","journal-title":"Int J Androl"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib63","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.fertnstert.2008.01.047","article-title":"Association of sperm apoptosis and DNA ploidy with sperm chromatin quality in human spermatozoa","volume":"91","author":"Mahfouz","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib64","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1006\/excr.1999.4586","article-title":"Abnormal sperm parameters in humans are indicative of an abortive apoptotic mechanism linked to the Fas-mediated pathway","volume":"251","author":"Sakkas","year":"1999","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib65","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1095\/biolreprod66.4.1061","article-title":"Nature of DNA damage in ejaculated human spermatozoa and the possible involvement of apoptosis","volume":"66","author":"Sakkas","year":"2002","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib66","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S0015-0282(16)58232-6","article-title":"Fertilization alter intracytoplasmic sperm injection with cryopreserved testicular spermatozoa","volume":"65","author":"Romero","year":"1996","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib67","first-page":"1035","article-title":"Spermatic recovery techniques for intracytoplasmic spermatozoid injection (ICSI) in male infertility","volume":"57","author":"Gil-Salom","year":"2004","journal-title":"Arch Esp Urol"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib68","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.reprotox.2006.03.013","article-title":"Meiotic chromosome abnormalities in human spermatogenesis","volume":"22","author":"Martin","year":"2006","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib69","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/1096-8628(20010215)99:1<34::AID-AJMG1106>3.0.CO;2-D","article-title":"Single sperm typing demonstrated that reduced recombination is associated with the production of aneuploid 24, XY human sperm","volume":"99","author":"Shi","year":"2001","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib70","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/humrep\/dei428","article-title":"Reduced recombination associated with the production of aneuploid sperm in an infertile man: a case report","volume":"21","author":"Ma","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib71","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/j.1939-4640.2003.tb02647.x","article-title":"Analysis of aneuploidy in spermatozoa from testicular biopsies from men with nonobstructive azoospermia","volume":"24","author":"Martin","year":"2003","journal-title":"J Androl"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib72","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S1472-6483(10)60131-9","article-title":"Paternal contribution to aneuploidy in preimplantation embryos","volume":"18","author":"Magli","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib73","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/S1472-6483(10)61057-7","article-title":"Maternal age, morphology, development and chromosome abnormalities in over 6000 cleavage-stage embryos","volume":"14","author":"Munn\u00e9","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2010.10.022_bib74","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/pd.1773","article-title":"Impact of chromosomal abnormalities on preimplantation embryo development","volume":"27","author":"Rubio","year":"2007","journal-title":"Prenat Diagn"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028210026981?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028210026981?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T06:09:13Z","timestamp":1762150153000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028210026981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":74,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S0015028210026981"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2010.10.022","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Testicular sperm from patients with obstructive and nonobstructive azoospermia: aneuploidy risk and reproductive prognosis using testicular sperm from fertile donors as control samples","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2010.10.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}