{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T15:42:03Z","timestamp":1792424523791,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:00:00Z","timestamp":1682294400000},"content-version":"vor","delay-in-days":4437,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1016\/j.fertnstert.2010.10.025","type":"journal-article","created":{"date-parts":[[2010,11,4]],"date-time":"2010-11-04T04:17:49Z","timestamp":1288844269000},"page":"867-871","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Proximal ectopic pregnancy: a descriptive general population\u2013based study and results of different management options in 86 cases"],"prefix":"10.1016","volume":"95","author":[{"given":"Demetrio","family":"Larra\u00edn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Marengo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Bourdel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Jaffeux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Aublet-Cuvelier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Pouly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Mage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Rabischong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2010.10.025_bib1","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/S0140-6736(06)68397-9","article-title":"WHO analysis of causes of maternal death: a systematic review","volume":"367","author":"Khan","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib2","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1093\/humrep\/17.12.3224","article-title":"Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases","volume":"17","author":"Bouyer","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib3","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0015-0282(99)00242-3","article-title":"Conservative medical and surgical management of interstitial ectopic pregnancy","volume":"72","author":"Lau","year":"1999","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2006.03.073","article-title":"Semantics and pitfalls in the diagnosis of cornual\/instersticial pregnancy","volume":"86","author":"Malinowski","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib5","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/jcu.1870150406","article-title":"Sonographic detection of interstitial pregnancy","volume":"15","author":"Jafri","year":"1987","journal-title":"J Clin Ultrasound"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib6","first-page":"1044","article-title":"Sonographic evolution of cornual pregnancies treated without surgery","volume":"79","author":"Timor-Tritsch","year":"1992","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib7","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1148\/radiology.189.1.8372223","article-title":"Interstitial line: sonographic finding in interstitial (cornual) ectopic pregnancy","volume":"189","author":"Ackerman","year":"1993","journal-title":"Radiology"},{"issue":"7 Suppl","key":"10.1016\/j.fertnstert.2010.10.025_bib8","first-page":"S93","article-title":"Management of other ectopic pregnancies (cornual, interstitial, angular, ovarian)","volume":"32","author":"Jourdain","year":"2003","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib9","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.bpobgyn.2008.12.011","article-title":"Treating nontubal ectopic pregnancy","volume":"23","author":"Chetty","year":"2009","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib10","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ajog.2009.07.054","article-title":"Current diagnosis and treatment of interstitial pregnancy","volume":"202","author":"Moawad","year":"2010","journal-title":"Am J Obstet Gynecol"},{"issue":"Suppl 3","key":"10.1016\/j.fertnstert.2010.10.025_bib11","first-page":"S206","article-title":"Medical treatment of ectopic pregnancy","volume":"90","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib12","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0002-9378(00)70499-6","article-title":"New simple endoscopic operations for interstitial pregnancies","volume":"182","author":"Moon","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib13","first-page":"87","article-title":"Mini-cornual excision: a simple stepwise laparoscopic technique for the treatment of cornual pregnancy","volume":"13","author":"Moawad","year":"2009","journal-title":"JSLS"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib14","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/S0140-6736(95)90977-X","article-title":"A cost-effectiveness study of a randomized trial of laparoscopy versus laparotomy for ectopic pregnancy","volume":"345","author":"Gray","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib15","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.fertnstert.2007.07.1288","article-title":"Laparoscopic treatment of cornual pregnancy: a series of 20 consecutive cases","volume":"90","author":"Soriano","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib16","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.fertnstert.2008.08.072","article-title":"Laparoscopic management of 53 cases of cornual ectopic pregnancy","volume":"92","author":"Ng","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib17","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/0029-7844(94)00423-B","article-title":"Laparoscopic treatment of interstitial pregnancy","volume":"85","author":"Tulandi","year":"1995","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib18","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jmig.2005.11.005","article-title":"Cornual gestation: a systematic literature review and two case reports of a novel treatment regimen","volume":"13","author":"Ross","year":"2006","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib19","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/oxfordjournals.humrep.a138582","article-title":"Incidence of ectopic pregnancy. First results of a population-based register in France","volume":"9","author":"Coste","year":"1994","journal-title":"Hum Reprod"},{"issue":"Suppl 1","key":"10.1016\/j.fertnstert.2010.10.025_bib20","first-page":"10","article-title":"Evaluation of the completeness of the Auvergne register of ectopic pregnancy with the capture-recapture method","volume":"43","author":"Coste","year":"1995","journal-title":"Rev Epidemiol Sante Publique"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib21","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1093\/oxfordjournals.aje.a116400","article-title":"The value of capture-recapture methods even for apparent exhaustive surveys. The need for adjustment for source of ascertainment intersection in attempted complete prevalence studies","volume":"135","author":"Hook","year":"1992","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib22","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0015-0282(16)54539-7","article-title":"Multifactorial analysis of fertility after conservative laparoscopic treatment of ectopic pregnancy in a series of 223 patients","volume":"56","author":"Pouly","year":"1991","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib23","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1034\/j.1600-0412.2003.00214.x","article-title":"Pitfalls in diagnosis of interstitial pregnancy","volume":"82","author":"Chan","year":"2003","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib24","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.bpobgyn.2008.12.010","article-title":"Diagnosis of ectopic pregnancy with ultrasound","volume":"23","author":"Kirk","year":"2009","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib25","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1067\/mem.2002.125426","article-title":"Interstitial pregnancy: a potential for misdiagnosis of ectopic pregnancy with emergency department ultrasonography","volume":"40","author":"DeWitt","year":"2002","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00330-004-2306-4","article-title":"Interstitial pregnancy: role of MRI","volume":"15","author":"Filhastre","year":"2005","journal-title":"Eur Radiol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib27","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.gyobfe.2006.06.023","article-title":"Interstitial pregnancy. Ultrasonographic diagnosis and contribution of MRI. A case report","volume":"35","author":"Bourdel","year":"2007","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib28","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1002\/jcu.10201","article-title":"Three-dimensional transvaginal sonography of interstitial pregnancy","volume":"31","author":"Izquierdo","year":"2003","journal-title":"J\u00a0Clin Ultrasound"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib29","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1111\/j.1471-0528.2004.00442.x","article-title":"The conservative management of interstitial pregnancy","volume":"111","author":"Jermy","year":"2004","journal-title":"BJOG"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib30","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s00404-006-0311-3","article-title":"Management of extra-tubal and rare ectopic pregnancies: case series and review of current literature","volume":"276","author":"Oliver","year":"2007","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib31","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/01.AOG.0000109218.24211.79","article-title":"Interstitial pregnancy: results generated from the Society of the Reproductive Surgeons Registry","volume":"103","author":"Tulandi","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib32","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/0002-9378(53)90167-7","article-title":"Interstitial pregnancy: a survey of 45 cases","volume":"66","author":"Felmus","year":"1953","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib33","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/aje\/kwf190","article-title":"Risk factors for ectopic pregnancy: a comprehensive analysis based on a large case-control, population-based study in France","volume":"157","author":"Bouyer","year":"2003","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib34","first-page":"S8","article-title":"Epidemiology of ectopic pregnancy: incidence, risk factors and outcomes","volume":"32","author":"Bouyer","year":"2003","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib35","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1067\/mob.2000.103620","article-title":"Cornual heterotopic pregnancy: contemporary management options","volume":"182","author":"Habana","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib36","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1046\/j.1469-0705.1994.04030238.x","article-title":"Expectant management of interstitial pregnancy","volume":"4","author":"Zalel","year":"1994","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib37","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S1074-3804(05)80229-4","article-title":"Operative laparoscopy for management of ectopic pregnancy in patients with hypovolemic shock","volume":"4","author":"Soriano","year":"1997","journal-title":"J Am Assoc Gynecol Laparosc"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib38","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1093\/oxfordjournals.humrep.a137476","article-title":"The use of a pretherapeutic, predictive score to determine inclusion criteria for the nonsurgical treatment of ectopic pregnancy","volume":"6","author":"Fernandez","year":"1991","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib39","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/uog.9","article-title":"Predictors of success in methotrexate treatment of women with unruptured tubal pregnancies","volume":"21","author":"Nazac","year":"2003","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib40","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1479-828X.2006.00537.x","article-title":"A medical management of interstitial ectopic pregnancy: a 5-year clinical study","volume":"46","author":"Tang","year":"2006","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib41","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/S0015-0282(16)46349-1","article-title":"Treatment of interstitial ectopic pregnancy with methotrexate: report of a successful case","volume":"37","author":"Tanaka","year":"1982","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib42","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0301-2115(95)02589-8","article-title":"Alternative to surgery of treatment of unruptured interstitial pregnancy: 15 cases of medical treatment","volume":"70","author":"Benifla","year":"1996","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib43","first-page":"521","article-title":"Medical treatment of interstitial pregnancy. A report of three unsuccessful cases","volume":"42","author":"Barnhart","year":"1997","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib44","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0015-0282(16)49886-9","article-title":"Conservative laparoscopic treatment of 321 ectopic pregnancies","volume":"46","author":"Pouly","year":"1986","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2010.10.025_bib45","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0029-7844(96)00370-5","article-title":"Methotrexate prophylaxis for persistent ectopic pregnancy after conservative treatment by salpingostomy","volume":"89","author":"Graczykowski","year":"1997","journal-title":"Obstet Gynecol"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028210027019?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028210027019?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:50:48Z","timestamp":1758009048000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028210027019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S0015028210027019"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2010.10.025","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Proximal ectopic pregnancy: a descriptive general population\u2013based study and results of different management options in 86 cases","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2010.10.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}