{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:53:37Z","timestamp":1791345217532,"version":"4.3.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":4013,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.fertnstert.2011.03.021","type":"journal-article","created":{"date-parts":[[2011,4,12]],"date-time":"2011-04-12T01:27:42Z","timestamp":1302571662000},"page":"2335-2341.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":176,"title":["Endometrial gene expression in the window of implantation is altered in obese women especially in\u00a0association with polycystic ovary syndrome"],"prefix":"10.1016","volume":"95","clinical-trial-number":[{"clinical-trial-number":"nct00505986","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Jos\u00e9","family":"Bellver","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"Mart\u00ednez-Conejero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Labarta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Alam\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Antonio Barreto","family":"Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Remoh\u00ed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Pellicer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"Horcajadas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2011.03.021_bib1","first-page":"1","article-title":"Fertility, family planning, and reproductive health of U.S. women: data from the 2002 National Survey of Family Growth","volume":"25","author":"Chandra","year":"2005","journal-title":"Vital Health Stat 23"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1001\/jama.2009.2014","article-title":"Prevalence and trends in obesity among US adults, 1999-2008","volume":"303","author":"Flegal","year":"2010","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1471-0528.2006.01180.x","article-title":"Trends in maternal obesity incidence rates, demographic predictors, and health inequalities in 36,821 women over a 15-year period","volume":"114","author":"Heslehurst","year":"2007","journal-title":"BJOG"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0002-9378(94)90465-0","article-title":"Adolescent body mass index and infertility caused by ovulatory disorder","volume":"171","author":"Rich-Edwards","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib5","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1046\/j.1467-789X.2001.00041.x","article-title":"The influence of obesity on hyperandrogenism and infertility in the female","volume":"2","author":"Diamanti-Kandarakis","year":"2001","journal-title":"Obes Rev"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib6","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1093\/humrep\/den357","article-title":"Waiting time to pregnancy according to maternal birthweight and prepregnancy BMI","volume":"24","author":"Nohr","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib7","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/humrep\/dep360","article-title":"An internet-based prospective study of body size and time-to-pregnancy","volume":"25","author":"Wise","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib8","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1016\/j.fertnstert.2008.12.059","article-title":"Association of adolescent obesity and lifetime nulliparity\u2014the Study of Women\u2019s Health Across the Nation (SWAN)","volume":"93","author":"Polotsky","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib9","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00001648-199403000-00016","article-title":"Body mass index and ovulatory infertility","volume":"5","author":"Grodstein","year":"1994","journal-title":"Epidemiology"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib10","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/00001648-200203000-00013","article-title":"Physical activity, body mass index, and ovulatory disorder infertility","volume":"13","author":"Rich-Edwards","year":"2002","journal-title":"Epidemiology"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib11","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/00001648-199907000-00014","article-title":"Fecundability in relation to body mass and menstrual cycle patterns","volume":"10","author":"Jensen","year":"1999","journal-title":"Epidemiology"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib12","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1093\/humrep\/del400","article-title":"Obesity and time to pregnancy","volume":"22","author":"Gesink Law","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib13","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1093\/humrep\/dem371","article-title":"Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women","volume":"23","author":"van der Steeg","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib14","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/humupd\/dmm017","article-title":"Effect of overweight and obesity on assisted reproductive technology\u2013a systematic review","volume":"13","author":"Maheshwari","year":"2007","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib15","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.fertnstert.2008.12.032","article-title":"Female obesity impairs in vitro fertilization outcome without affecting embryo quality","volume":"93","author":"Bellver","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib16","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/humrep\/deq306","article-title":"SART Writing Group. Female obesity adversely affects assisted reproductive technology (ART) pregnancy and live birth rates","volume":"26","author":"Luke","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib17","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.fertnstert.2007.07.1290","article-title":"Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence","volume":"90","author":"Metwally","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib18","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1093\/humrep\/deh277","article-title":"Obesity is associated with increased risk of first trimester and recurrent miscarriage: matched case control study","volume":"19","author":"Lashen","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib19","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/01.ogx.0000158509.04154.9e","article-title":"Obesity and pregnancy","volume":"4","author":"Hall","year":"2005","journal-title":"Obstet Gynaecol Surv"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib20","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/S1472-6483(10)61181-9","article-title":"Obesity and assisted reproduction technology outcomes","volume":"12","author":"Bellver","year":"2006","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib21","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/01.AOG.0000253311.44696.85","article-title":"Management of obesity in pregnancy","volume":"109","author":"Catalano","year":"2007","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib22","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.fertnstert.2006.11.162","article-title":"Obesity and poor reproductive outcome: the potential role of the endometrium","volume":"88","author":"Bellver","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib23","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1159\/000084347","article-title":"Obesity and Clomiphene Challenge Test as predictors of outcome of in vitro fertilization and intracytoplasmic sperm injection","volume":"59","author":"van Swieten","year":"2005","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib24","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S1472-6483(10)60385-9","article-title":"Effect of increased body mass index on oocyte and embryo quality in IVF patients","volume":"15","author":"Metwally","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib25","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1093\/humrep\/14.3.712","article-title":"Extremes of body mass do not adversely affect the outcome of superovulation and in-vitro fertilization","volume":"14","author":"Lashen","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib26","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S0015-0282(02)04807-0","article-title":"Extremes of body mass index reduce in vitro fertilization pregnancy rates","volume":"79","author":"Nichols","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib27","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/j.fertnstert.2009.07.1005","article-title":"Surrogate obesity negatively impacts pregnancy rates in third-party reproduction","volume":"93","author":"DeUgarte","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib28","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1093\/humrep\/dep303","article-title":"Determinants of pregnancy rate in the donor oocyte model: a multivariate analysis of 450 frozen-thawed embryo transfers","volume":"24","author":"Dessolle","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib29","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S1472-6483(10)60690-6","article-title":"Is ovarian stimulation detrimental to the endometrium?","volume":"15","author":"Mart\u00ednez-Conejero","year":"2007","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib30","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/molehr\/gah150","article-title":"Effect of controlled ovarian hyperstimulation in IVF on endometrial gene expression profiles","volume":"11","author":"Horcajadas","year":"2005","journal-title":"Mol Human Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib31","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.fertnstert.2003.10.004","article-title":"Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome","volume":"81","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib32","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1471-2105-11-48","article-title":"Power and sample size estimation in microarray studies","volume":"11","author":"Lin","year":"2010","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib33","doi-asserted-by":"crossref","first-page":"3490","DOI":"10.1210\/jc.2008-0565","article-title":"Endometrial receptivity and implantation are not affected by the presence of uterine intramural leiomyomas: a clinical and functional genomics analysis","volume":"93","author":"Horcajadas","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib34","unstructured":"R Development Core Team: R: A language and environment for statistical computing 2004. Vienna: R Foundation for Statistical Computing; 2004."},{"key":"10.1016\/j.fertnstert.2011.03.021_bib35","doi-asserted-by":"crossref","first-page":"P3","DOI":"10.1186\/gb-2003-4-5-p3","article-title":"DAVID: Database for Annotation, Visualization, and Integrated Discovery","volume":"4","author":"Dennis","year":"2003","journal-title":"Genome Biol"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib36","doi-asserted-by":"crossref","first-page":"374","DOI":"10.2144\/03342mt01","article-title":"TM4: a free, open-source system for microarray data management and analysis","volume":"34","author":"Saeed","year":"2003","journal-title":"Biotechniques"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib37","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/humupd\/dml046","article-title":"Wide genomic analysis of human endometrial receptivity: new times, new opportunities","volume":"13","author":"Horcajadas","year":"2007","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib38","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/nrendo.2009.195","article-title":"Nutritional programming of the metabolic syndrome","volume":"5","author":"Symonds","year":"2009","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib39","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1016\/j.fertnstert.2008.08.005","article-title":"Obesity and reproduction: an educational bulletin","volume":"90","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib40","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1136\/bmj.306.6876.484","article-title":"Fat and female fecundity: prospective study of effect of body fat distribution on conception rates","volume":"306","author":"Zaadstra","year":"1993","journal-title":"BMJ"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib41","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1093\/humrep\/12.9.2057","article-title":"An android body fat distribution in females impairs the pregnancy rate of in-vitro fertilization-embryo transfer","volume":"12","author":"Wass","year":"1997","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib42","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1093\/oxfordjournals.humrep.a136313","article-title":"Clinical evidence for a detrimental effect on uterine receptivity of high serum oestradiol concentrations in high and normal reponder patients","volume":"10","author":"Simon","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib43","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1080\/00016340701415152","article-title":"Effects of ovarian high response on implantation and pregnancy outcome during controlled ovarian hyperstimulation (with GnRH agonist and rFSH)","volume":"86","author":"Chen","year":"2007","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib44","doi-asserted-by":"crossref","first-page":"4500","DOI":"10.1210\/jc.2008-0588","article-title":"Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications","volume":"11","author":"Horcajadas","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib45","first-page":"887","article-title":"In vitro fertilization (IVF): why doing it in unstimulated cycles?","volume":"35","author":"Basille","year":"2007","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib46","doi-asserted-by":"crossref","first-page":"3318","DOI":"10.1093\/humrep\/dei243","article-title":"Similar endometrial development in oocyte donors treated with high- or low-dose GnRH-antagonist compared to GnRH-agonist treatment and natural cycles","volume":"12","author":"Sim\u00f3n","year":"2005","journal-title":"Human Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib47","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/molehr\/gag037","article-title":"Gene expression profiling of human endometrial receptivity on days LH+2 versus LH+7 by microarray technology","volume":"9","author":"Riesewijk","year":"2003","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib48","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1586\/17474108.3.4.487","article-title":"Are favourite molecules of endometrial receptivity still in favour?","volume":"3","author":"Aghajanova","year":"2008","journal-title":"Expert Rev Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib49","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1093\/humrep\/dep222","article-title":"Is there a uniform basal endometrial gene expression profile during the implantation window in women who became pregnant in a subsequent ICSI cycle?","volume":"24","author":"Allegra","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.03.021_bib50","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/molehr\/gap102","article-title":"Endometrial gene expression analysis at the time of embryo implantation in women with unexplained infertility","volume":"16","author":"Altm\u00e4e","year":"2010","journal-title":"Mol Hum Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028211004304?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028211004304?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:50:51Z","timestamp":1758009051000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028211004304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":50,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0015028211004304"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2011.03.021","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endometrial gene expression in the window of implantation is altered in obese women especially in\u00a0association with polycystic ovary syndrome","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2011.03.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}