{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:26:23Z","timestamp":1792679183872,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":3768,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","fertstert.org","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.fertnstert.2011.11.003","type":"journal-article","created":{"date-parts":[[2011,12,8]],"date-time":"2011-12-08T01:04:46Z","timestamp":1323306286000},"page":"313-318","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Normal live birth after testicular sperm extraction and intracytoplasmic sperm injection in\u00a0variant primary ciliary dyskinesia with completely immotile sperm and\u00a0structurally abnormal sperm tails"],"prefix":"10.1016","volume":"97","author":[{"given":"Robert I.","family":"McLachlan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomomoto","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiki","family":"Osianlis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna Jo","family":"Merriner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Healy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"de Kretser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moira K.","family":"O\u2019Bryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2011.11.003_bib1","unstructured":"Baker HGW. Clinical management of male infertility. In: Endocrinology of male reproduction 2008. Available at: http:\/\/www.endotext.org\/male\/index.htm."},{"key":"10.1016\/j.fertnstert.2011.11.003_bib2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1146\/annurev.genom.7.080505.115610","article-title":"The ciliopathies: an emerging class of human genetic disorders","volume":"7","author":"Badano","year":"2006","journal-title":"Annu Rev Genomics Hum Genet"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib3","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/GIM.0b013e3181a53562","article-title":"Clinical and genetic aspects of primary ciliary dyskinesia\/Kartagener syndrome","volume":"11","author":"Leigh","year":"2009","journal-title":"Genet Med"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib4","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1164\/rccm.200601-084OC","article-title":"DNAH5 mutations are a common cause of primary ciliary dyskinesia with outer dynein arm defects","volume":"174","author":"Hornef","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM197707072970101","article-title":"The immotile-cilia syndrome. A congenital ciliary abnormality as an etiologic factor in chronic airway infections and male sterility","volume":"297","author":"Eliasson","year":"1977","journal-title":"N Engl J Med"},{"issue":"Suppl 1","key":"10.1016\/j.fertnstert.2011.11.003_bib6","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/humrep\/13.suppl_1.143","article-title":"Special applications of intracytoplasmic sperm injection: the influence of sperm count, motility, morphology, source and sperm antibody on the outcome of ICSI","volume":"13","author":"Nagy","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib7","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0015-0282(01)01974-4","article-title":"Birth after intracytoplasmic sperm injection with use of testicular sperm from men with Kartagener\/immotile cilia syndrome","volume":"76","author":"Cayan","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib8","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/molehr\/gap049","article-title":"The role of centrosomes in mammalian fertilization and its significance for ICSI","volume":"15","author":"Schatten","year":"2009","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib9","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1093\/humrep\/14.10.2517","article-title":"Failure of fertilization after intracytoplasmic sperm injection in a patient with Kartagener\u2019s syndrome and totally immotile spermatozoa: case report","volume":"14","author":"Abu-Musa","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib10","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1093\/humrep\/15.1.135","article-title":"Successful in-vitro fertilization pregnancy with spermatozoa from a patient with Kartagener\u2019s syndrome: case report","volume":"15","author":"Kay","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib11","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/S0015-0282(97)80087-8","article-title":"Therapeutic approach of immotile cilia syndrome by intracytoplasmic sperm injection: a case report","volume":"67","author":"Papadimas","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib12","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/S1472-6483(10)61777-4","article-title":"Pregnancy after ICSI with ejaculated immotile spermatozoa from a patient with immotile cilia syndrome: a case report and review of the literature","volume":"9","author":"Peeraer","year":"2004","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib13","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1093\/oxfordjournals.humrep.a136244","article-title":"Pregnancy and birth after intracytoplasmic sperm injection with spermatozoa from a patient with tail stump syndrome","volume":"10","author":"Stalf","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib14","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0015-0282(98)00246-5","article-title":"Birth of healthy children after intracytoplasmic sperm injection in two couples with male Kartagener\u2019s syndrome","volume":"70","author":"von Zumbusch","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib15","series-title":"WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction","year":"1999"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib16","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1136\/thorax.55.4.314","article-title":"Analysis of ciliary beat pattern and beat frequency using digital high speed imaging: comparison with the photomultiplier and photodiode methods","volume":"55","author":"Chilvers","year":"2000","journal-title":"Thorax"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib17","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ajhg.2009.01.011","article-title":"Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities","volume":"84","author":"Castleman","year":"2009","journal-title":"Am J\u00a0Hum Genet"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib18","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.ajhg.2009.11.008","article-title":"Loss-of-function mutations in the human ortholog of Chlamydomonas reinhardtii ODA7 disrupt dynein arm assembly and cause primary ciliary dyskinesia","volume":"85","author":"Duquesnoy","year":"2009","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib19","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/nature07471","article-title":"Ktu\/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins","volume":"456","author":"Omran","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib20","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1136\/jmg.2008.061176","article-title":"Mutations in DNAH5 account for only 15% of a nonpreselected cohort of patients with primary ciliary dyskinesia","volume":"46","author":"Failly","year":"2009","journal-title":"J Med Genet"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib21","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1159\/000128567","article-title":"DNAI1 mutations explain only 2% of primary ciliary dykinesia","volume":"76","author":"Failly","year":"2008","journal-title":"Respiration"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib22","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1164\/rccm.200603-370OC","article-title":"Mutations of DNAI1 in primary ciliary dyskinesia: evidence of founder effect in a common mutation","volume":"174","author":"Zariwala","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib23","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/BF00347027","article-title":"Ultrastructural features of human spermiogenesis","volume":"98","author":"de Kretser","year":"1969","journal-title":"Z Zellforsch Mikrosk Anat"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib24","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/BF00221701","article-title":"Morphology of the \u201cspindle-shaped body\u201d in the developing tail of human spermatids","volume":"159","author":"Wartenberg","year":"1975","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib25","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1439-0272.1979.tb02235.x","article-title":"\u201c9 + 0\u201d immotile spermatozoa in an infertile man","volume":"11","author":"Baccetti","year":"1979","journal-title":"Andrologia"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib26","doi-asserted-by":"crossref","first-page":"6298","DOI":"10.1128\/MCB.22.17.6298-6305.2002","article-title":"Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6","volume":"22","author":"Sapiro","year":"2002","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib27","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/ncb2040","article-title":"Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia","volume":"12","author":"Guirao","year":"2010","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib28","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1038\/ng1644","article-title":"Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates","volume":"37","author":"Ross","year":"2005","journal-title":"Nat Genet"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib29","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S1472-6483(10)60455-5","article-title":"The centrosome and early embryogenesis: clinical insights","volume":"16","author":"Chatzimeletiou","year":"2008","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib30","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1093\/oxfordjournals.humrep.a019384","article-title":"Pregnancies achieved with testicular and ejaculated spermatozoa in combination with intracytoplasmic sperm injection in men with totally or initially immotile spermatozoa in the ejaculate","volume":"11","author":"Kahraman","year":"1996","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib31","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1093\/oxfordjournals.humrep.a135758","article-title":"Analysis of 76 total fertilization failure cycles out of 2732 intracytoplasmic sperm injection cycles","volume":"10","author":"Liu","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib32","doi-asserted-by":"crossref","first-page":"497.e9","DOI":"10.1016\/j.fertnstert.2006.11.113","article-title":"Birth after intracytoplasmic sperm injection with use of testicular sperm from men with Kartagener or immotile cilia syndrome","volume":"88","author":"Kaushal","year":"2007","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib33","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1093\/humrep\/deg240","article-title":"Different fertilization rates between immotile testicular spermatozoa and immotile ejaculated spermatozoa for ICSI in men with Kartagener\u2019s syndrome: case reports","volume":"18","author":"Westlander","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2011.11.003_bib34","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1093\/oxfordjournals.humrep.a019073","article-title":"Fertilizing ability of immotile spermatozoa after intracytoplasmic sperm injection","volume":"11","author":"Nijs","year":"1996","journal-title":"Hum Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028211027579?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028211027579?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T02:50:48Z","timestamp":1663901448000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028211027579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0015028211027579"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2011.11.003","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Normal live birth after testicular sperm extraction and intracytoplasmic sperm injection in\u00a0variant primary ciliary dyskinesia with completely immotile sperm and\u00a0structurally abnormal sperm tails","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2011.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}