{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:34:16Z","timestamp":1790836456551,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":3708,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.fertnstert.2012.01.093","type":"journal-article","created":{"date-parts":[[2012,1,31]],"date-time":"2012-01-31T03:37:04Z","timestamp":1327981024000},"page":"930-934","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":130,"title":["Ovarian response to controlled ovarian hyperstimulation in cancer patients is diminished even before oncological treatment"],"prefix":"10.1016","volume":"97","author":[{"given":"Javier","family":"Domingo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Guill\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanira","family":"Ayll\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elkin","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Pellicer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan A.","family":"Garcia-Velasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2012.01.093_bib1","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1093\/jnci\/91.12.1051","article-title":"Cancer surveillance series: recent trends in childhood cancer incidence and mortality in the United States","volume":"91","author":"Linet","year":"1999","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib2","series-title":"Surveillance, Epidemiology and End Results Program, 1975\u20132003","year":"2006"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib3","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1097\/GRF.0b013e3181f96e00","article-title":"Fertility preservation in women with breast cancer","volume":"53","author":"Rodr\u00edguez-Wallberg","year":"2010","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib4","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1517\/14656566.2011.522568","article-title":"Medical approaches to preservation of fertility in female cancer patients","volume":"12","author":"Del Mastro","year":"2011","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib5","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1634\/theoncologist.11-5-422","article-title":"Fertility preservation in young women undergoing breast cancer therapy","volume":"11","author":"Sonmezer","year":"2006","journal-title":"Oncologist"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ajog.2011.01.025","article-title":"Fertility preserving options in patients with gynecologic malignancies","volume":"205","author":"Eskander","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib7","doi-asserted-by":"crossref","first-page":"5307","DOI":"10.1210\/jc.2003-030352","article-title":"Reduced ovarian function in a long-term survivors of radiation and chemotherapy-treated childhood cancer","volume":"88","author":"Larsen","year":"2003","journal-title":"J Clin Endocrinol Met"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib8","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.fertnstert.2008.10.007","article-title":"Ovarian stimulation for fertility preservation in patients with cancer","volume":"93","author":"Quintero","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib9","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/humupd\/dml032","article-title":"Ovarian tissue cryopreservation and transplantation: a review","volume":"12","author":"Donnez","year":"2006","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib10","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/j.fertnstert.2007.05.050","article-title":"Comparison of concomitant outcome achieved with fresh and cryopreserved oocytes vitrified by the Cryotop method","volume":"89","author":"Cobo","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib11","doi-asserted-by":"crossref","first-page":"268.e11","DOI":"10.1016\/j.fertnstert.2009.09.046","article-title":"Twins born after transplantation of ovarian cortical tissue and oocyte vitrification","volume":"93","author":"S\u00e1nchez-Serrano","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib12","doi-asserted-by":"crossref","first-page":"2917","DOI":"10.1200\/JCO.2006.06.5888","article-title":"American Society of Clinical Oncology recommendations on fertility preservation in cancer patients","volume":"24","author":"Lee","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib13","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S1472-6483(10)60837-1","article-title":"Highly efficient vitrification method for cryopreservation of human oocytes","volume":"11","author":"Kuwayama","year":"2005","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib14","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1093\/humrep\/den055","article-title":"Searching for evidence of disease and malignant cell contamination in ovarian tissue stored from hematologic cancer patients","volume":"23","author":"Meirow","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib15","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1182\/blood-2010-01-265751","article-title":"Reimplantation of cryopreserved ovarian tissue from patients with acute lymphoblastic leukemia is potentially unsafe","volume":"116","author":"Dolmans","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib16","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1093\/humrep\/dep196","article-title":"Malignant cells are not found in ovarian cortex from breast cancer patients undergoing ovarian cortex cryopreservation","volume":"24","author":"S\u00e1nchez-Serrano","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib17","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/S0140-6736(04)17222-X","article-title":"Livebirth after orthotopic transplantation of cryopreserved ovarian tissue","volume":"364","author":"Donnez","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib18","doi-asserted-by":"crossref","first-page":"437","DOI":"10.3109\/07853890.2010.546807","article-title":"Children born after autotransplantation of cryopreserved ovarian tissue: a review of 13 live births","volume":"43","author":"Donnez","year":"2011","journal-title":"Ann Med"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib19","doi-asserted-by":"crossref","first-page":"3885","DOI":"10.1210\/jc.2006-0962","article-title":"Letrozole reduces estrogen and gonadotropin exposure in women with breast cancer undergoing ovarian stimulation before chemotherapy","volume":"91","author":"Oktay","year":"2006","journal-title":"J Clin Endocrinol Metabol"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib20","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/AOG.0b013e318183fbd5","article-title":"ACOG Committee Opinion. Aromatase inhibitors in gynecologic practice","volume":"112","year":"2008","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib21","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/humupd\/dmr008","article-title":"GnRH agonist for triggering of final oocyte maturation: time for a change of practice?","volume":"17","author":"Humaidan","year":"2011","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib22","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.fertnstert.2005.01.117","article-title":"Aromatase inhibitor letrozole increases the concentration of intraovarian androgens and improves in\u00a0vitro fertilization outcome in low responder patients: a pilot study","volume":"84","author":"Garcia-Velasco","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib23","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/GRF.0b013e3181f9718f","article-title":"In\u00a0vitro maturation of oocytes as a strategy for fertility preservation","volume":"53","author":"Ata","year":"2010","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib24","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1093\/humrep\/deg473","article-title":"Depletion of ovarian reserve in young women after treatment for cancer in childhood: detection by anti-Mull\u00ebrian hormone, inhibin B and ovarian ultrasound","volume":"18","author":"Bath","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib25","doi-asserted-by":"crossref","first-page":"2125.e9","DOI":"10.1016\/j.fertnstert.2011.01.030","article-title":"Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles","volume":"95","author":"S\u00f6nmezer","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib26","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1200\/JCO.2009.24.2057","article-title":"Association of BRCA1 mutations with occult primary insufficiency: a possible explanation for the link between infertility and breast\/ovarian cancer risks","volume":"28","author":"Oktay","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib27","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1016\/j.fertnstert.2008.12.052","article-title":"The hereditary breast cancer clinical study group. Fertility in women with BRCA mutations: a case-control study","volume":"93","author":"Pal","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib28","doi-asserted-by":"crossref","first-page":"4835","DOI":"10.1210\/jc.2008-2269","article-title":"Correlation of telomere length and telomerase activity with occult ovarian insufficiency","volume":"94","author":"Butts","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2012.01.093_bib29","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1093\/humupd\/dmn033","article-title":"Use of letrozole in assisted reproduction: a systematic review and meta-analysis","volume":"14","author":"Requena","year":"2008","journal-title":"Hum Reprod Update"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212001227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212001227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T06:10:59Z","timestamp":1762150259000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028212001227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0015028212001227"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.01.093","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ovarian response to controlled ovarian hyperstimulation in cancer patients is diminished even before oncological treatment","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.01.093","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}