{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T10:07:06Z","timestamp":1785146826308,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":3708,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.fertnstert.2012.01.113","type":"journal-article","created":{"date-parts":[[2012,2,15]],"date-time":"2012-02-15T07:59:55Z","timestamp":1329292795000},"page":"953-958","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Expression of leukemia inhibitory factor in the endometrium in abnormal uterine cavities during the implantation window"],"prefix":"10.1016","volume":"97","author":[{"given":"Ei","family":"Hasegawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroe","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiko","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Hatano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kazuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saburo","family":"Usuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Isaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2012.01.113_bib1","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1016\/j.fertnstert.2008.03.029","article-title":"Submucosal uterine leiomyomas have a global effect in molecular determinants of endometrial receptivity","volume":"93","author":"Rackow","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib2","first-page":"169","article-title":"Uterine factors and infertility","volume":"51","author":"Sanders","year":"2006","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib3","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1159\/000084513","article-title":"Effect of fibroids on fertility in patients undergoing assisted reproduction. A structured literature review","volume":"59","author":"Benecke","year":"2005","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib4","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.rbmo.2009.06.011","article-title":"The effect of hysteroscopic polypectomy on the concentrations of endometrial implantation factors in uterine flushings","volume":"19","author":"Ben-Nagi","year":"2009","journal-title":"Reprod Biomed Online"},{"issue":"6390","key":"10.1016\/j.fertnstert.2012.01.113_bib5","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/359076a0","article-title":"Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor","volume":"359","author":"Stewart","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib6","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1530\/JOE-10-0461","article-title":"Bridging endometrial receptivity and implantation: network of hormones, cytokines and growth factors","volume":"210","author":"Singh","year":"2011","journal-title":"J Endocrinol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib7","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1530\/jrf.0.1010421","article-title":"Leukaemia inhibitory factor mRNA concentration peaks in human endometrium at the time of implantation and the blastocyst contains mRNA for the receptor at this time","volume":"101","author":"Charnock-Jones","year":"1994","journal-title":"J Reprod Fertil"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib8","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1093\/oxfordjournals.humrep.a136328","article-title":"Molecular aspects of implantation: in-vitro endometrial secretion of human interleukin for DA cells\/leukaemia inhibitory factor by explants cultures from fertile and infertile women","volume":"10","author":"Delage","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib9","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1093\/HUMREP\/10.6.1579","article-title":"Molecular aspects of implantation: The signals and molecular pathways involved in implantation, a symbiotic interaction between blastocyst and endometrium involving adhesion and tissue invasion","volume":"10","author":"Tabibzadeh","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib10","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/dbio.2000.9767","article-title":"Embryo implantation","volume":"223","author":"Carson","year":"2000","journal-title":"Dev Biol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib11","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1210\/er.2003-0020","article-title":"Molecular cues to implantation","volume":"25","author":"Dey","year":"2004","journal-title":"Endocr Rev"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib12","first-page":"83","article-title":"Cytokines, deciduas, and early pregnancy","volume":"15","author":"Clark","year":"1993","journal-title":"Oxf Rev Reprod Biol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib13","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1139\/o92-135","article-title":"Mechanisms of placental invasion of the uterus and their control","volume":"70","author":"Graham","year":"1992","journal-title":"Biochem Cell Biol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib14","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1053\/beog.2000.0121","article-title":"Paracrine regulators of implantation","volume":"14","author":"Simon","year":"2000","journal-title":"Baillieres Best Pract Res Clin Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib15","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1477-7827-3-20","article-title":"TGF-beta expression during rat pregnancy and activity on decidual cell survival","volume":"3","author":"Shooner","year":"2005","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib16","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.1093\/humrep\/del225","article-title":"Leukaemia inhibitory factor and interleukin 11 levels in uterine flushings of infertile patients with endometriosis","volume":"21","author":"Mikolajczyk","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib17","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0968-0004(92)90505-4","article-title":"LIF: lots of interesting functions","volume":"17","author":"Hilton","year":"1992","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib18","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1749-6632.1994.tb21743.x","article-title":"The role of leukaemia inhibitory factor (LIF) and other cytokines in regulating implantation in mammals","volume":"734","author":"Stewart","year":"1994","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib19","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1242\/dev.121.5.1283","article-title":"Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death","volume":"121","author":"Ware","year":"1995","journal-title":"Development"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib20","first-page":"1908","article-title":"Modulation of leukemia inhibitory factor gene expression and protein biosynthesis in human endometrium","volume":"80","author":"Arici","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib21","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jri.2004.08.007","article-title":"Expression of interleukin-11 receptor alpha and interleukin-11 protein in the endometrium of normal fertile women and women with recurrent miscarriage","volume":"64","author":"Linjawi","year":"2004","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib22","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0165-0378(00)00089-9","article-title":"Interleukin-11 (IL-11) in human endometrium: expression throughout the menstrual cycle and the effects of cytokines on endometrial IL-11 production in\u00a0vitro","volume":"50","author":"Cork","year":"2001","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib23","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1093\/molehr\/6.10.907","article-title":"Expression of interleukin-11 during the human menstrual cycle: coincidence with stromal cell decidualization and relationship to leukaemia inhibitory factor and prolactin","volume":"6","author":"Dimitriadis","year":"2000","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib24","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1093\/molehr\/gah107","article-title":"Interleukin-11 expression: its significance in eutopic and ectopic human implantation","volume":"10","author":"von Rango","year":"2004","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib25","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1477-7827-7-30","article-title":"Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome","volume":"7","author":"Serafini","year":"2009","journal-title":"Reprd Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib26","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0015-0282(16)45789-4","article-title":"Uterine leiomyomata: etiology, symptomatology, and management","volume":"36","author":"Buttram","year":"1981","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.01.113_bib27","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.fertnstert.2009.03.075","article-title":"Submucous myomas and their implications in the pregnancy rates of patients with otherwise unexplained primary infertility undergoing hysteroscopic myomectomy: a randomized matched control study","volume":"94","author":"Shokeir","year":"2010","journal-title":"Fertil Steril"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212001720?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212001720?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:57:04Z","timestamp":1758009424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028212001720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0015028212001720"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.01.113","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression of leukemia inhibitory factor in the endometrium in abnormal uterine cavities during the implantation window","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.01.113","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}