{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T14:32:45Z","timestamp":1793975565862,"version":"4.8.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1016\/j.fertnstert.2012.07.1061","type":"journal-article","created":{"date-parts":[[2012,8,29]],"date-time":"2012-08-29T10:23:09Z","timestamp":1346235789000},"page":"564-571","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":433,"title":["Deep endometriosis: definition, diagnosis, and treatment"],"prefix":"10.1016","volume":"98","author":[{"given":"Philippe R.","family":"Koninckx","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia","family":"Ussia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Adamyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Wattiez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Donnez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2012.07.1061_bib1","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.jmig.2010.04.005","article-title":"The elephant in the room: quality control of endometriosis data","volume":"17","author":"Koninckx","year":"2010","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib2","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.jmig.2008.08.012","article-title":"Pathophysiology of cyclic hemorrhagic ascites and endometriosis","volume":"15","author":"Ussia","year":"2008","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib3","first-page":"1161","article-title":"Mullerianosis","volume":"22","author":"Batt","year":"2007","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib4","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.fertnstert.2011.06.037","article-title":"Is the baboon model appropriate for endometriosis studies?","volume":"96","author":"Dehoux","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib5","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/GCO.0b013e328348a29a","article-title":"Laparoscopic ureteral repair in gynaecological surgery","volume":"23","author":"De","year":"2011","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib6","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S0015-0282(16)55436-3","article-title":"Deep endometriosis: a consequence of infiltration or retraction or possibly adenomyosis externa?","volume":"58","author":"Koninckx","year":"1992","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib7","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/S0015-0282(16)53570-5","article-title":"Deeply infiltrating pelvic endometriosis: histology and clinical significance","volume":"53","author":"Cornillie","year":"1990","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib8","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0301-2115(98)00200-0","article-title":"Biases in the endometriosis literature. Illustrated by 20 years of endometriosis research in Leuven","volume":"81","author":"Koninckx","year":"1998","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib9","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1093\/humrep\/deq135","article-title":"Complications, pregnancy and recurrence in a prospective series of 500 patients operated on by the shaving technique for deep rectovaginal endometriotic nodules","volume":"25","author":"Donnez","year":"2010","journal-title":"Hum Reprod"},{"issue":"Suppl 1","key":"10.1016\/j.fertnstert.2012.07.1061_bib10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1159\/000052853","article-title":"Implantation versus infiltration: the Sampson versus the endometriotic disease theory","volume":"47","author":"Koninckx","year":"1999","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib11","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/humupd\/4.5.741","article-title":"Endometriotic disease: the role of peritoneal fluid","volume":"4","author":"Koninckx","year":"1998","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib12","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0301-2115(98)00200-0","article-title":"Biases in the endometriosis literature\u2014illustrated by 20 years of endometriosis research in Leuven","volume":"81","author":"Koninckx","year":"1998","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib13","doi-asserted-by":"crossref","first-page":"333","DOI":"10.3109\/00016349409015774","article-title":"CO2-laser excision of endometriosis does not improve the decreased natural killer activity","volume":"73","author":"Oosterlynck","year":"1994","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib14","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/S0015-0282(03)01181-6","article-title":"Analysis of the clonality of ectopic glands in peritoneal endometriosis using laser microdissection","volume":"80","author":"Nabeshima","year":"2003","journal-title":"Fertil Steril"},{"issue":"Suppl 1","key":"10.1016\/j.fertnstert.2012.07.1061_bib15","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/S0015-0282(02)04821-5","article-title":"Resolution of clonal origins for endometriotic lesions using laser capture microdissection and the human androgen receptor (HUMARA) assay","volume":"79","author":"Wu","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib16","first-page":"1173","article-title":"Evidence for monoclonal expansion of epithelial cells in ovarian endometrial cysts","volume":"150","author":"Jimbo","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib17","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1093\/humrep\/deq332","article-title":"Surgical management of deep infiltrating endometriosis of the rectum: pleading for a symptom-guided approach","volume":"26","author":"Roman","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib18","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1471-0528.2010.02744.x","article-title":"Bowel resection for deep endometriosis: a systematic review","volume":"118","author":"De Cicco","year":"2011","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib19","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0015-0282(16)58086-8","article-title":"Diagnosis of deep endometriosis by clinical examination during menstruation and plasma CA-125 concentration","volume":"65","author":"Koninckx","year":"1996","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib20","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/uog.8858","article-title":"Diagnostic accuracy of transvaginal ultrasound for non-invasive diagnosis of bowel endometriosis: systematic review and meta-analysis","volume":"37","author":"Hudelist","year":"2011","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib21","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/jmri.22832","article-title":"MRI and \"tenderness guided\" transvaginal ultrasonography in the diagnosis of recto-sigmoid endometriosis","volume":"35","author":"Saba","year":"2012","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib22","doi-asserted-by":"crossref","first-page":"e331","DOI":"10.1016\/j.ejrad.2010.12.006","article-title":"Deep pelvic endometriosis: limited additional diagnostic value of postcontrast in comparison with conventional MR images","volume":"80","author":"Bazot","year":"2011","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib23","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1002\/uog.7746","article-title":"Value of transvaginal sonography in assessing severe pelvic endometriosis","volume":"36","author":"Bazot","year":"2010","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib24","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1016\/j.fertnstert.2008.09.005","article-title":"Diagnostic accuracy of physical examination, transvaginal sonography, rectal endoscopic sonography, and magnetic resonance imaging to diagnose deep infiltrating endometriosis","volume":"92","author":"Bazot","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib25","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1093\/humupd\/1.2.173","article-title":"CA125 and endometriosis","volume":"1","author":"Muyldermans","year":"1995","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib26","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jmig.2010.08.692","article-title":"Preoperative evaluation of posterior deep-infiltrating endometriosis demonstrates a relationship with urinary dysfunction and parametrial involvement","volume":"18","author":"Ballester","year":"2011","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib27","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jmig.2008.01.006","article-title":"Endometriosis lesions that compromise the rectum deeper than the inner muscularis layer have more than 40% of the circumference of the rectum affected by the disease","volume":"15","author":"Abrao","year":"2008","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib28","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.fertnstert.2008.08.021","article-title":"Laparoscopic management of ureteral lesions in gynecology","volume":"92","author":"De Cicco","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib29","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s00384-011-1361-y","article-title":"Mechanical bowel preparation for elective colorectal surgery: updated systematic review and meta-analysis","volume":"27","author":"Cao","year":"2012","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib30","first-page":"28","article-title":"The role of mechanical bowel preparation in gynecologic laparoscopy","volume":"4","author":"Cohen","year":"2011","journal-title":"Rev Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib31","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.ajog.2011.05.010","article-title":"Perioperative bowel management for gynecologic surgery","volume":"205","author":"Fanning","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib32","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.yasu.2011.03.008","article-title":"Is there a role for bowel preparation and oral or parenteral antibiotics in infection control in contemporary colon surgery?","volume":"45","author":"Galandiuk","year":"2011","journal-title":"Adv Surg"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib33","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/humrep\/dep014","article-title":"Can transvaginal sonography predict infiltration depth in patients with deep infiltrating endometriosis of the rectum?","volume":"24","author":"Hudelist","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib34","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.jmig.2011.07.014","article-title":"Quality of life after segmental resection of the rectosigmoid by laparoscopy in patients with deep infiltrating endometriosis with bowel involvement","volume":"18","author":"Bassi","year":"2011","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib35","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1093\/humrep\/dep433","article-title":"Transvaginal ultrasonography with bowel preparation is able to predict the number of lesions and rectosigmoid layers affected in cases of deep endometriosis, defining surgical strategy","volume":"25","author":"Goncalves","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib36","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.jmig.2008.07.010","article-title":"The recent article \"Endometriosis lesions that compromise the rectum deeper than the inner muscularis layer have more than 40% of the circumference of the rectum affected by the disease.\"","volume":"15","author":"Koninckx","year":"2008","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib37","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.mehy.2010.12.018","article-title":"Regional lymphatic spread in women with pelvic endometriosis","volume":"76","author":"Gong","year":"2011","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib38","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1111\/j.1447-0756.2010.01467.x","article-title":"Rectal endometriosis with invasion into lymph nodes","volume":"37","author":"Namkung","year":"2011","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib39","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.fertnstert.2011.06.070","article-title":"Lymphatic spread of endometriosis to pelvic sentinel lymph nodes: a prospective clinical study","volume":"96","author":"Tempfer","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib40","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1111\/j.1471-0528.2008.01941.x","article-title":"Accident analysis: factors contributing to a ureteric injury during deep endometriosis surgery","volume":"115","author":"Schonman","year":"2008","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib41","doi-asserted-by":"crossref","first-page":"387","DOI":"10.4293\/108680811X13125733356396","article-title":"Robotic-assisted laparoscopic treatment of bowel, bladder, and ureteral endometriosis","volume":"15","author":"Nezhat","year":"2011","journal-title":"J Soc Laparoendosc Surg"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib42","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1016\/j.fertnstert.2010.04.031","article-title":"Robotic versus standard laparoscopy for the treatment of endometriosis","volume":"94","author":"Nezhat","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib43","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jmig.2006.07.015","article-title":"Outcome after rectum or sigmoid resection: a review for gynecologists","volume":"14","author":"Ret Davalos","year":"2007","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib44","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S1472-6483(10)60267-2","article-title":"Outcome after multidisciplinary CO2 laser laparoscopic excision of deep infiltrating colorectal endometriosis","volume":"18","author":"Meuleman","year":"2009","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib45","doi-asserted-by":"crossref","first-page":"303.e1","DOI":"10.1016\/j.ajog.2010.11.011","article-title":"Urinary dysfunction after colorectal resection for endometriosis: results of a prospective randomized trial comparing laparoscopy to open surgery","volume":"204","author":"Ballester","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib46","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00192-011-1492-2","article-title":"Prevalence and outcome of urinary retention after laparoscopic surgery for severe endometriosis\u2014does histology provide answers?","volume":"23","author":"Gabriel","year":"2012","journal-title":"Int Urogynecol J"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib47","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.fertnstert.2010.07.1043","article-title":"Long-term urinary retention after laparoscopic surgery for deep endometriosis","volume":"95","author":"Kovoor","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib48","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1093\/oxfordjournals.humrep.a019087","article-title":"Complications of CO2-laser endoscopic excision of deep endometriosis","volume":"11","author":"Koninckx","year":"1996","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib49","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jmig.2007.12.001","article-title":"Videoregistration of surgery should be used as a quality control","volume":"15","author":"Koninckx","year":"2008","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.fertnstert.2012.07.1061_bib50","series-title":"Gynecological endoscopic surgery","first-page":"19","article-title":"Surgical treatment of deeply infiltrating endometriosis","author":"Koninckx","year":"1997"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212017979?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212017979?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:58:38Z","timestamp":1758009518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028212017979"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["S0015028212017979"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.07.1061","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717956758.793461333","asserted-by":"object"}]},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deep endometriosis: definition, diagnosis, and treatment","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.07.1061","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}