{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T04:30:44Z","timestamp":1761971444423,"version":"build-2065373602"},"reference-count":6,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":3494,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.fertnstert.2012.08.031","type":"journal-article","created":{"date-parts":[[2012,9,8]],"date-time":"2012-09-08T12:00:36Z","timestamp":1347105636000},"page":"e25","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Klinefelter syndrome: an argument for early aggressive hormonal and fertility management"],"prefix":"10.1016","volume":"98","author":[{"given":"Fatma Ferda","family":"Verit","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayhan","family":"Verit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2012.08.031_bib1","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.fertnstert.2012.06.001","article-title":"Klinefelter syndrome: an argument for early aggressive hormonal and fertility management","volume":"98","author":"Mehta","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2012.08.031_bib2","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1093\/humrep\/des002","article-title":"Failure of a combined clinical- and hormonal-based strategy to detect early spermatogenesis and retrieve spermatogonial stem cells in 47, XXY boys by single testicular biopsy","volume":"27","author":"Gies","year":"2012","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2012.08.031_bib3","first-page":"317","article-title":"Testicular function in Klinefelter syndrome","volume":"69","author":"Wikstr\u00f6m","year":"2008","journal-title":"Horm Res"},{"key":"10.1016\/j.fertnstert.2012.08.031_bib4","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1210\/jc.2003-031725","article-title":"Klinefelter syndrome in adolescence: onset of puberty is associated with accelerated germ cell depletion","volume":"89","author":"Wikstr\u00f6m","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2012.08.031_bib5","doi-asserted-by":"crossref","DOI":"10.2164\/jandrol.111.016329","article-title":"The high frequency of sperm aneuploidy in Klinefelter patients and in non-obstructive azoospermia is due to meiotic errors in euploid spermatocytes","author":"Vialard","year":"2012","journal-title":"J Androl"},{"key":"10.1016\/j.fertnstert.2012.08.031_bib6","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1093\/humrep\/dep431","article-title":"Should non-mosaic Klinefelter syndrome men be labeled as infertile in 2009?","volume":"25","author":"Fullerton","year":"2010","journal-title":"Hum Reprod"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212020833?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028212020833?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:02:02Z","timestamp":1758009722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028212020833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":6,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0015028212020833"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.08.031","relation":{},"ISSN":["0015-0282"],"issn-type":[{"type":"print","value":"0015-0282"}],"subject":[],"published":{"date-parts":[[2012,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Klinefelter syndrome: an argument for early aggressive hormonal and fertility management","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.08.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2012.06.001","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}