{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:32:24Z","timestamp":1778113944507,"version":"3.51.4"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":3037,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.fertnstert.2013.10.006","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T18:16:00Z","timestamp":1383329760000},"page":"340-343","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia"],"prefix":"10.1016","volume":"101","author":[{"given":"Thomas","family":"Ebner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Shebl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard Bernhard","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Moser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Costamoling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Oppelt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2013.10.006_bib1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0140-6736(92)92425-F","article-title":"Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte","volume":"340","author":"Palermo","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib2","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0301-2115(00)00347-X","article-title":"The origin of spermatozoa does not affect intracytoplasmic sperm injection outcome","volume":"94","author":"Bukulmez","year":"2001","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib3","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1093\/oxfordjournals.humrep.a138778","article-title":"Conventional in-vitro fertilization versus intracytoplasmic sperm injection for patients requiring microsurgical sperm aspiration","volume":"9","author":"Silber","year":"1994","journal-title":"Humanit Rep"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib4","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0015-0282(16)56958-1","article-title":"Normal fertilization of human oocytes after testicular sperm extraction and intracytoplasmic sperm injection","volume":"62","author":"Devroey","year":"1994","journal-title":"Fertil Steril"},{"issue":"Suppl 1","key":"10.1016\/j.fertnstert.2013.10.006_bib5","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/humrep\/13.suppl_1.134","article-title":"Results of intracytoplasmic sperm injection with ejaculated, fresh and frozen-thawed epididymal and testicular spermatozoa","volume":"13","author":"Van Steirteghem","year":"1998","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib6","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1093\/humrep\/14.1.90","article-title":"No differences in outcome after intracytoplasmic sperm injection with fresh or with frozen-thawed epididymal spermatozoa","volume":"14","author":"Tournaye","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib7","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0015-0282(16)60325-4","article-title":"Successful pregnancies from men with retrograde ejaculation with the use of washed sperm and gamete intrafallopian tube transfer (GIFT)","volume":"50","author":"Vernon","year":"1988","journal-title":"Fertil Steril"},{"issue":"Suppl 1","key":"10.1016\/j.fertnstert.2013.10.006_bib8","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1111\/j.1439-0272.2011.01224.x","article-title":"Birth of healthy twins after intracytoplasmic sperm injection using ejaculated immotile spermatozoa from a patient with Kartagener's syndrome","volume":"44","author":"Geber","year":"2012","journal-title":"Andrologia"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib9","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s00404-008-0671-y","article-title":"Can pentoxifylline improve the sperm motion and ICSI success in the primary ciliary dyskinesia?","volume":"279","author":"Yildirim","year":"2009","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib10","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/humupd\/dmr018","article-title":"Absolute asthenozoospermia and ICSI: what are the options?","volume":"17","author":"Ortega","year":"2011","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib11","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1093\/oxfordjournals.humrep.a136104","article-title":"The result of intracytoplasmic sperm injection is not related to any of the three basic sperm parameters","volume":"10","author":"Nagy","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib12","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0301-2115(02)00434-7","article-title":"Successful pregnancies after using immotile spermatozoa from ejaculate, epididymis and testis","volume":"108","author":"Rhouma","year":"2003","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib13","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S1472-6483(10)62006-8","article-title":"Is oocyte morphology prognostic of embryo developmental potential after ICSI","volume":"12","author":"Ebner","year":"2006","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib14","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.fertnstert.2011.11.019","article-title":"The management of retrograde ejaculation: a systematic review and update","volume":"97","author":"Jefferys","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib15","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.fertnstert.2011.08.041","article-title":"Pharmacological stimulation of sperm motility in frozen and thawed testicular sperm using the dimethylxanthine theophylline","volume":"96","author":"Ebner","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib16","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1093\/oxfordjournals.humrep.a138697","article-title":"Pregnancy after intracytoplasmic sperm injection of metaphase II oocytes with spermatozoa from a man with complete retrograde ejaculation","volume":"9","author":"Gerris","year":"1994","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib17","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1093\/humrep\/14.9.2293","article-title":"The outcome of intracytoplasmic sperm injection in patients with retrograde ejaculation","volume":"14","author":"Nikolettos","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib18","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/S0015-0282(97)00249-5","article-title":"Birth after combination of cryopreservation of sperm recovered from urine and intracytoplasmic sperm injection in a case of complete retrograde ejaculation","volume":"68","author":"Jimenez","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib19","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1093\/humrep\/deh083","article-title":"Pregnancy with frozen\u2013thawed and fresh testicular biopsy after motile and immotile sperm microinjection, using the mechanical touch technique to assess viability","volume":"19","author":"De Oliveira","year":"2004","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib20","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0015-0282(97)81533-6","article-title":"High fertilization rate obtained after intracytoplasmic sperm injection with 100% nonmotile spermatozoa selected by using a simple modified hypo-osmotic swelling test","volume":"68","author":"Liu","year":"1997","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib21","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/j.1439-0272.2004.00636.x","article-title":"Use of a laser to detect viable but immotile spermatozoa","volume":"36","author":"Aktan","year":"2004","journal-title":"Andrologia"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib22","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/S0015-0282(00)00559-8","article-title":"In situ use of pentoxifylline to assess sperm vitality in intracytoplasmic sperm injection for treatment of patients with total lack of sperm movement","volume":"74","author":"de Mendoza","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2013.10.006_bib23","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1016\/j.fertnstert.2011.03.074","article-title":"Birth of a healthy infant after intracytoplasmic sperm injection using pentoxifylline-activated sperm from a patient with Kartagener's syndrome","volume":"95","author":"Hattori","year":"2011","journal-title":"Fertil Steril"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028213031233?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028213031233?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T17:58:05Z","timestamp":1773251885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028213031233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S0015028213031233"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2013.10.006","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2013.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}