{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:13:12Z","timestamp":1785427992367,"version":"3.56.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T00:00:00Z","timestamp":1705708800000},"content-version":"vor","delay-in-days":3275,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.fertnstert.2014.11.007","type":"journal-article","created":{"date-parts":[[2014,12,13]],"date-time":"2014-12-13T08:48:40Z","timestamp":1418460520000},"page":"503-512","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["First systematic experience of preimplantation genetic diagnosis for single-gene disorders, and\/or preimplantation human leukocyte antigen typing, combined with 24-chromosome aneuploidy testing"],"prefix":"10.1016","volume":"103","author":[{"given":"Svetlana","family":"Rechitsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Pakhalchuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"San Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Goodman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zev","family":"Zlatopolsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anver","family":"Kuliev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2014.11.007_bib1","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.fertnstert.2011.06.049","article-title":"Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray\u2013based comprehensive chromosome screening in infertile patients","volume":"96","author":"Schoolcraft","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib2","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1016\/j.fertnstert.2010.11.004","article-title":"Single nucleotide polymorphism microarray-based concurrent screening of 24-chromosome aneuploidy and unbalanced translocations in preimplantation human embryos","volume":"95","author":"Treff","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib3","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.fertnstert.2012.01.104","article-title":"Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study","volume":"97","author":"Scott","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib4","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1755-8166-5-24","article-title":"Selection of single blastocysts for fresh transfer via standard morphology assessment alone and with array CGH for good prognosis IVF patients: results from a randomized pilot study","volume":"5","author":"Yang","year":"2012","journal-title":"Mol Cytogenet"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib5","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/humrep\/des020","article-title":"Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates","volume":"27","author":"Forman","year":"2012","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib6","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.fertnstert.2013.01.094","article-title":"Use of array comparative genomic hybridization (array-CGH) for embryo assessment: clinical results","volume":"99","author":"Rubio","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib7","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/j.fertnstert.2013.07.2002","article-title":"Diminished effect of maternal age on implantation after preimplantation genetic diagnosis with array comparative genomic hybridization","volume":"100","author":"Harton","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib8","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1136\/jmedgenet-2014-102497","article-title":"Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation","volume":"51","author":"Wells","year":"2014","journal-title":"J Med Genet"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib9","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.fertnstert.2014.01.051","article-title":"Development and validation of a next-generation sequencing-based protocol for 24-chromosome aneuploidy screening of embryos","volume":"101","author":"Fiorentino","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib10","series-title":"Atlas of preimplantation genetic diagnosis","year":"2005"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib11","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/j.fertnstert.2012.12.018","article-title":"Evaluation of targeted next-generation sequencing-based preimplantation genetic diagnosis of monogenic disorders","volume":"99","author":"Treff","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib12","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.fertnstert.2013.01.112","article-title":"Next generation sequencing for preimplantation genetic diagnosis","volume":"99","author":"Simpson","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib13","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/nature09807","article-title":"Tumour evolution inferred by single-cell sequencing","volume":"472","author":"Navin","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib14","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.cell.2012.06.030","article-title":"Genome-wide single-cell analysis of recombination activity and de novo mutation rates in human sperm","volume":"150","author":"Wang","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib15","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.fertnstert.2013.02.001","article-title":"The impact of next-generation sequencing technology on preimplantation genetic diagnosis and screening","volume":"99","author":"Martin","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib16","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1136\/jmg.2009.069971","article-title":"Karyomapping: a novel molecular karyotyping method based on mapping crossovers between parental haplotypes with broad applications for preimplantation genetic diagnosis of inherited disease","volume":"47","author":"Handyside","year":"2010","journal-title":"J Med Genet"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib17","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/j.fertnstert.2010.11.025","article-title":"Single-gene testing combined with single nucleotide polymorphism microarray preimplantation genetic diagnosis for aneuploidy: a novel approach in optimizing pregnancy outcome","volume":"95","author":"Brezina","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib18","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1023\/A:1022532108472","article-title":"Allele drop out in polar bodies and blastomeres","volume":"15","author":"Rechitsky","year":"1998","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib19","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S1472-6483(10)60986-8","article-title":"Preimplantation HLA typing with aneuploidy testing","volume":"12","author":"Rechitsky","year":"2006","journal-title":"Reprod BioMedicine Online"},{"key":"10.1016\/j.fertnstert.2014.11.007_bib20","series-title":"Atlas of preimplantation genetic diagnosis","year":"2014"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502821402353X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001502821402353X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:16:51Z","timestamp":1758010611000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001502821402353X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S001502821402353X"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2014.11.007","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"First systematic experience of preimplantation genetic diagnosis for single-gene disorders, and\/or preimplantation human leukocyte antigen typing, combined with 24-chromosome aneuploidy testing","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2014.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}