{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T23:40:53Z","timestamp":1790552453976,"version":"4.1.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":2094,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","fertstert.org","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.fertnstert.2016.08.021","type":"journal-article","created":{"date-parts":[[2016,8,31]],"date-time":"2016-08-31T05:43:09Z","timestamp":1472622189000},"page":"857-863","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"title":["Bisphenol A and ovarian steroidogenesis"],"prefix":"10.1016","volume":"106","author":[{"given":"Michael S.","family":"Bloom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Mok-Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Y.","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2016.08.021_bib1","first-page":"14","article-title":"Debating BPA\u2019s toxicity","volume":"89","author":"Ritter","year":"2011","journal-title":"Chem Eng News"},{"issue":"Suppl 3","key":"10.1016\/j.fertnstert.2016.08.021_bib2","doi-asserted-by":"crossref","first-page":"S559","DOI":"10.2105\/AJPH.2008.159228","article-title":"The politics of plastics: the making and unmaking of bisphenol A \u201csafety\u201d","volume":"99","author":"Vogel","year":"2009","journal-title":"Am J Public Health"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib3","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1038\/137996a0","article-title":"Synthetic oestrogenic agents without the phenanthrene nucleus [letter]","volume":"137","author":"Dodds","year":"1936","journal-title":"Nature"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.reprotox.2007.07.010","article-title":"Human exposure to bisphenol A (BPA)","volume":"24","author":"Vandenberg","year":"2007","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib5","doi-asserted-by":"crossref","first-page":"6761","DOI":"10.1021\/es200977t","article-title":"High levels of bisphenol A in paper currencies from several countries, and implications for dermal exposure","volume":"45","author":"Liao","year":"2011","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib6","doi-asserted-by":"crossref","first-page":"9372","DOI":"10.1021\/es202507f","article-title":"Widespread occurrence of bisphenol A in paper and paper products: implications for human exposure","volume":"45","author":"Liao","year":"2011","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib7","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.reprotox.2007.05.010","article-title":"In\u00a0vitro molecular mechanisms of bisphenol A action","volume":"24","author":"Wetherill","year":"2007","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.reprotox.2007.06.004","article-title":"In\u00a0vivo effects of bisphenol A in laboratory rodent studies","volume":"24","author":"Richter","year":"2007","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib9","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1210\/endo.138.3.4979","article-title":"Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors and \u03b1 and \u03b2","volume":"138","author":"Kuiper","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib10","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/bdrb.20147","article-title":"NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A","volume":"83","author":"Chapin","year":"2008","journal-title":"Birth Defects Res B Dev Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib11","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.toxlet.2006.08.012","article-title":"Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERR gamma) with high constitutive activity","volume":"167","author":"Takayanagi","year":"2006","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib12","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1289\/ehp.7505","article-title":"Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-alpha-mediated Ca2+ fluxes and prolactin release in GH3\/B6 pituitary tumor cells","volume":"113","author":"Wozniak","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib13","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1210\/er.2015-1010","article-title":"EDC-2: The Endocrine Society\u2019s second scientific statement on endocrine-disrupting chemicals","volume":"36","author":"Gore","year":"2015","journal-title":"Endocr Rev"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib14","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1289\/ehp.1307728","article-title":"Bisphenol A and reproductive health: update of experimental and human evidence, 2007\u20132013","volume":"122","author":"Peretz","year":"2014","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1477-7827-12-37","article-title":"Bisphenol A and the female reproductive tract: an overview of recent laboratory evidence and epidemiological studies","volume":"12","author":"Caserta","year":"2014","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib16","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.reprotox.2013.08.008","article-title":"Bisphenol A and human health: a review of the literature","volume":"42","author":"Rochester","year":"2013","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib17","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/jes.2010.9","article-title":"Daily intake of bisphenol A and potential sources of exposure: 2005\u20132006 National Health and Nutrition Examination Survey","volume":"21","author":"Lakind","year":"2011","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib18","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1289\/ehp.1003170","article-title":"Food packaging and bisphenol A and bis(2-ethyhexyl) phthalate exposure: findings from a dietary intervention","volume":"119","author":"Rudel","year":"2011","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib19","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.envint.2015.06.008","article-title":"Pharmacokinetics of bisphenol A in humans following a single oral administration","volume":"83","author":"Thayer","year":"2015","journal-title":"Environ Int"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib20","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1021\/tx0001833","article-title":"In\u00a0vitro and in\u00a0vivo interactions of bisphenol A and its metabolite, bisphenol A glucuronide, with estrogen receptors \u03b1 and \u03b2","volume":"14","author":"Matthews","year":"2001","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib21","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1021\/tx025548t","article-title":"Metabolism and kinetics of bisphenol A in humans at low doses following oral administration","volume":"15","author":"Volkel","year":"2002","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib22","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1530\/eje.0.1450513","article-title":"Bisphenol-A, an environmental estrogen, activates the human orphan nuclear receptor, steroid and xenobiotic receptor-mediated transcription","volume":"145","author":"Takeshita","year":"2001","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.canlet.2004.10.007","article-title":"Cytochrome P450\u2013mediated metabolism of estrogens and its regulation in human","volume":"227","author":"Tsuchiya","year":"2005","journal-title":"Cancer Lett"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib24","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/oxfordjournals.jncimonographs.a024234","article-title":"Chapter 6: estrogen metabolism by conjugation","volume":"2000","author":"Raftogianis","year":"2000","journal-title":"JNCI Monogr"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib25","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1021\/tx500087p","article-title":"Modulation of metabolizing enzymes by bisphenol A in human and animal models","volume":"27","author":"Quesnot","year":"2014","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib26","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/10937404.2014.882194","article-title":"Estrogenic endocrine-disrupting chemicals: molecular mechanisms of actions on putative human diseases","volume":"17","author":"Yoon","year":"2014","journal-title":"J Toxicol Environ Health B Crit Rev"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib27","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.scitotenv.2013.07.040","article-title":"Association between urinary levels of bisphenol-A and estrogen metabolism in Korean adults","volume":"470","author":"Kim","year":"2014","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.reprotox.2013.03.008","article-title":"Changes in steroid metabolism among girls with precocious puberty may not be associated with urinary levels of bisphenol A","volume":"44","author":"Lee","year":"2014","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib29","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/aje\/kwv043","article-title":"Epidemiology\u2019s continuing contribution to public health: the power of \u201cthen and now\u201d","volume":"181","author":"Buck Louis","year":"2015","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib30","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.fct.2013.08.001","article-title":"Are typical human serum BPA concentrations measurable and sufficient to be estrogenic in the general population?","volume":"62","author":"Teeguarden","year":"2013","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib31","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1515\/reveh-2012-0034","article-title":"Human exposures to bisphenol A: mismatches between data and assumptions","volume":"28","author":"Vandenberg","year":"2013","journal-title":"Rev Environ Health"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib32","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1093\/humrep\/dev183","article-title":"Urinary bisphenol A concentrations and association with in\u00a0vitro fertilization outcomes among women from a fertility clinic","volume":"30","author":"Minguez-Alarcon","year":"2015","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib33","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1476-069X-13-25","article-title":"A round robin approach to the analysis of bisphenol A (BPA) in human blood samples","volume":"13","author":"Vandenberg","year":"2014","journal-title":"Environ Health"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib34","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1186\/bcr3494","article-title":"Misuse of blood serum to assess exposure to bisphenol A and phthalates","volume":"15","author":"Calafat","year":"2013","journal-title":"Breast Cancer Res"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib35","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1289\/ehp.7534","article-title":"Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population","volume":"113","author":"Calafat","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib36","doi-asserted-by":"crossref","DOI":"10.1177\/1559325815598308","article-title":"Global assessment of bisphenol A in the environment: review and analysis of its occurrence and bioaccumulation","volume":"13","author":"Corrales","year":"2015","journal-title":"Dose Response"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib37","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ijgo.2015.09.002","article-title":"International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals","volume":"131","author":"Di Renzo","year":"2015","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib38","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1097\/01.AOG.0000435416.21944.54","article-title":"Committee opinion no. 575: exposure to toxic environmental agents","volume":"122","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib39","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s40471-016-0060-1","article-title":"Female infertility and \u201cemerging\u201d organic pollutants of concern","volume":"3","author":"Bloom","year":"2016","journal-title":"Curr Epidemiol Rep"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib40","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1093\/humrep\/17.11.2839","article-title":"Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure","volume":"17","author":"Ikezuki","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib41","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s10815-012-9775-1","article-title":"Phthalates and bisphenol do not accumulate in human follicular fluid","volume":"29","author":"Krotz","year":"2012","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib42","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0303-7207(94)90278-X","article-title":"Follicular oestrogen synthesis: the \u201ctwo-cell, two-gonadotrophin\u201d model revisited","volume":"100","author":"Hillier","year":"1994","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib43","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/417087a","article-title":"Rapid regulation of steroidogenesis by mitochondrial protein import","volume":"417","author":"Bose","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib44","article-title":"Genes and proteins of the alternative steroid backdoor pathway for dihydrotestosterone synthesis are expressed in the human ovary and seem enhanced in the polycystic ovary syndrome","author":"Marti","year":"2016","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib45","first-page":"1265","article-title":"Insulin preincubation enhances insulin-like growth factor-II (IGF-II) action on steroidogenesis in human granulosa cells","volume":"78","author":"Mason","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib46","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1210\/en.2004-1046","article-title":"Activation of peroxisome proliferator\u2013activated receptor-gamma and retinoid X receptor inhibits aromatase transcription via nuclear factor-kappa B","volume":"146","author":"Fan","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib47","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1210\/mend-4-1-3","article-title":"Aromatase cytochrome p450 in rat ovarian granulosa cells before and after luteinization: adenosine 3\u2032,5\u2032-monophosphate\u2013dependent and independent regulation. Cloning and sequencing of rat aromatase cDNA and 5\u2032 genomic DNA","volume":"4","author":"Hickey","year":"1990","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib48","first-page":"1309","article-title":"Identification of a cyclic adenosine 3\u2032,5\u2032-monophosphate\u2013response element in the rat aromatase promoter that is required for transcriptional activation in rat granulosa cells and r2c leydig cells","volume":"8","author":"Fitzpatrick","year":"1994","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib49","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1210\/jcem-69-4-716","article-title":"Insulin-like growth factor-I regulates aromatase activity in human granulosa and granulosa luteal cells","volume":"69","author":"Erickson","year":"1989","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib50","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1210\/jcem-70-4-894","article-title":"The effects of insulin and insulin-like growth factors-I and -II on estradiol production by granulosa cells of polycystic ovaries","volume":"70","author":"Erickson","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib51","doi-asserted-by":"crossref","first-page":"11387","DOI":"10.1074\/jbc.M010043200","article-title":"Bone morphogenetic protein-15 inhibits follicle-stimulating hormone (FSH) action by suppressing FSH receptor expression","volume":"276","author":"Otsuka","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib52","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1677\/joe.1.06503","article-title":"Growth differentiation factor-9 has divergent effects on proliferation and steroidogenesis of bovine granulosa cells","volume":"189","author":"Spicer","year":"2006","journal-title":"J Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib53","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1095\/biolreprod62.2.370","article-title":"Growth differentiation factor-9 stimulates proliferation but suppresses the follicle-stimulating hormone-induced differentiation of cultured granulosa cells from small antral and preovulatory rat follicles","volume":"62","author":"Vitt","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib54","doi-asserted-by":"crossref","first-page":"6077","DOI":"10.1016\/S0021-9258(20)65107-9","article-title":"Estrogens augment the stimulation of ovarian aromatase activity by follicle-stimulating hormone in cultured rat granulosa cells","volume":"257","author":"Adashi","year":"1982","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib55","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1210\/endo-129-3-1452","article-title":"Regulation of cytochrome P450 aromatase messenger ribonucleic acid and activity by steroids and gonadotropins in rat granulosa cells","volume":"129","author":"Fitzpatrick","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib56","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1095\/biolreprod63.5.1331","article-title":"Estrogen receptors alpha and beta in the female reproductive tract of the rat during the estrous cycle","volume":"63","author":"Wang","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib57","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1210\/en.2005-0213","article-title":"Estrogen receptor-beta is critical to granulosa cell differentiation and the ovulatory response to gonadotropins","volume":"146","author":"Couse","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib58","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1210\/mend.16.3.0806","article-title":"Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-1, estrogen, and the gonadotropins","volume":"16","author":"Richards","year":"2002","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib59","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/toxsci\/kfq319","article-title":"Bisphenol A impairs follicle growth, inhibits steroidogenesis, and downregulates rate-limiting enzymes in the estradiol biosynthesis pathway","volume":"119","author":"Peretz","year":"2011","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib60","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.taap.2013.04.028","article-title":"Bisphenol A down-regulates rate-limiting Cyp11a1 to acutely inhibit steroidogenesis in cultured mouse antral follicles","volume":"271","author":"Peretz","year":"2013","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib61","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.mce.2007.10.010","article-title":"Effect of bisphenol A on steroid hormone production in rat ovarian theca-interstitial and granulosa cells","volume":"283","author":"Zhou","year":"2008","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib62","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.mce.2005.02.009","article-title":"Alterations in steroid hormone production by porcine ovarian granulosa cells caused by bisphenol A and bisphenol A dimethacrylate","volume":"244","author":"Mlynarcikova","year":"2005","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib63","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.toxlet.2009.06.853","article-title":"Bisphenol A downregulates CYP19 transcription in JEG-3 cells","volume":"189","author":"Huang","year":"2009","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib64","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.toxlet.2012.01.020","article-title":"Effects of bisphenol A on the expression of cytochrome P450 aromatase (CYP19) in human fetal osteoblastic and granulosa cell-like cell lines","volume":"210","author":"Watanabe","year":"2012","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib65","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1289\/ehp.0901161","article-title":"Peroxisome proliferator-activated receptor-gamma mediates bisphenol A inhibition of FSH-stimulated IGF-1, aromatase, and estradiol in human granulosa cells","volume":"118","author":"Kwintkiewicz","year":"2010","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib66","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1093\/humrep\/dew088","article-title":"Does BPA alter steroid hormone synthesis in human granulosa cells in\u00a0vitro?","volume":"31","author":"Mansur","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib67","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.etap.2014.10.015","article-title":"Exposure to a low dose of bisphenol A impairs pituitary-ovarian axis in prepubertal rats. Effects on early folliculogenesis","volume":"39","author":"Gamez","year":"2015","journal-title":"Environ Toxicol Pharmacol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib68","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.reprotox.2013.09.002","article-title":"Prepubertal bisphenol A exposure interferes with ovarian follicle development and its relevant gene expression","volume":"44","author":"Li","year":"2014","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib69","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.taap.2015.10.010","article-title":"Exposure to bisphenol A in young adult mice does not alter ovulation but does alter the fertilization ability of oocytes","volume":"289","author":"Moore-Ambriz","year":"2015","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib70","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1365-2605.2009.01014.x","article-title":"Urinary bisphenol A concentrations and ovarian response among women undergoing IVF","volume":"33","author":"Mok-Lin","year":"2010","journal-title":"Int J Androl"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib71","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.fertnstert.2011.06.063","article-title":"Bisphenol A exposure reduces the estradiol response to gonadotropin stimulation during in\u00a0vitro fertilization","volume":"96","author":"Bloom","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib72","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.1093\/humrep\/des328","article-title":"Urinary bisphenol A concentrations and early reproductive health outcomes among women undergoing IVF","volume":"27","author":"Ehrlich","year":"2012","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib73","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.reprotox.2013.06.071","article-title":"Urinary bisphenol A concentrations and cytochrome P450 19 A1 (Cyp19) gene expression in ovarian granulosa cells: an in\u00a0vivo human study","volume":"42","author":"Ehrlich","year":"2013","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.fertnstert.2016.08.021_bib74","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1093\/humupd\/dmi032","article-title":"Using infertile patients in epidemiologic studies on subfecundity and embryonal loss","volume":"11","author":"Olsen","year":"2005","journal-title":"Hum Reprod Update"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028216627188?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028216627188?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,10,23]],"date-time":"2022-10-23T06:39:00Z","timestamp":1666507140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028216627188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":74,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0015028216627188"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2016.08.021","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bisphenol A and ovarian steroidogenesis","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2016.08.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a92016 American Society for Reproductive Medicine, Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}