{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:01:38Z","timestamp":1790704898262,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["275201300023I\/27500017"],"award-info":[{"award-number":["275201300023I\/27500017"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["275201400013C"],"award-info":[{"award-number":["275201400013C"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["275201200005C"],"award-info":[{"award-number":["275201200005C"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["267200700019C"],"award-info":[{"award-number":["267200700019C"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["275201300026I\/27500004"],"award-info":[{"award-number":["275201300026I\/27500004"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.fertnstert.2021.03.011","type":"journal-article","created":{"date-parts":[[2021,4,3]],"date-time":"2021-04-03T19:46:13Z","timestamp":1617479173000},"page":"493-504","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Conception by fertility treatment and offspring deoxyribonucleic acid methylation"],"prefix":"10.1016","volume":"116","author":[{"given":"Edwina H.","family":"Yeung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Mendola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeshwari","family":"Sundaram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuehuo","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihua","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Y.","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia L.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy E.","family":"Stern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhgar","family":"Ghassabian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"O\u2019Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Segars","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"Gore-Langton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin M.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2021.03.011_bib1","article-title":"ART in Europe, 2015: results generated from European registries by ESHRE","volume":"2020","author":"De Geyter","year":"2020","journal-title":"Hum Reprod Open"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12958-016-0225-2","article-title":"Systematic review of worldwide trends in assisted reproductive technology 2004\u20132013","volume":"15","author":"Kushnir","year":"2017","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss6804a1","article-title":"Assisted reproductive technology surveillance\u2014United States, 2016","volume":"68","author":"Sunderam","year":"2019","journal-title":"MMWR Surveill Summ"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib4","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1093\/aje\/kwp281","article-title":"Estimation of the contribution of non-assisted reproductive technology ovulation stimulation fertility treatments to US singleton and multiple births","volume":"170","author":"Schieve","year":"2009","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib5","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.fertnstert.2011.09.037","article-title":"Are there subtle genome-wide epigenetic alterations in normal offspring conceived by assisted reproductive technologies?","volume":"96","author":"Batcheller","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib6","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1095\/biolreprod62.6.1526","article-title":"Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo","volume":"62","author":"Doherty","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib7","series-title":"Epigenetics and human reproduction","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-3-642-14773-9_1","article-title":"Potential epigenetic consequences associated with assisted reproduction","author":"Fortier","year":"2011"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.mce.2014.03.003","article-title":"Modulation of imprinted gene expression following superovulation","volume":"388","author":"Fortier","year":"2014","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/humrep\/del316","article-title":"Aberrant DNA methylation of imprinted loci in superovulated oocytes","volume":"22","author":"Sato","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib10","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1242\/dev.01241","article-title":"Selective loss of imprinting in the placenta following preimplantation development in culture","volume":"131","author":"Mann","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13148-019-0623-3","article-title":"Association of four imprinting disorders and ART","volume":"11","author":"Hattori","year":"2019","journal-title":"Clin Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib12","doi-asserted-by":"crossref","first-page":"2826","DOI":"10.1093\/humrep\/den310","article-title":"A review of known imprinting syndromes and their association with assisted reproduction technologies","volume":"23","author":"Amor","year":"2008","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib13","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1177\/1933719118802052","article-title":"Aberrant DNA methylation of IGF2-H19 locus in human fetus and in spermatozoa from assisted reproductive technologies","volume":"26","author":"Lou","year":"2018","journal-title":"Reprod Sci"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib14","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/s13148-018-0511-2","article-title":"rs10732516 polymorphism at the IGF2\/H19 locus associates with genotype-specific effects on placental DNA methylation and birth weight of newborns conceived by assisted reproductive technology","volume":"10","author":"Marjonen","year":"2018","journal-title":"Clin Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib15","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1093\/humrep\/des459","article-title":"Placentas from pregnancies conceived by IVF\/ICSI have a reduced DNA methylation level at the H19 and MEST differentially methylated regions","volume":"28","author":"Nelissen","year":"2013","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib16","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.placenta.2015.08.008","article-title":"Altered gene expression of H19 and IGF2 in placentas from ART pregnancies","volume":"36","author":"Sakian","year":"2015","journal-title":"Placenta"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib17","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ejogrb.2011.04.001","article-title":"Abnormal methylation patterns at the IGF2\/H19 imprinting control region in phenotypically normal babies conceived by assisted reproductive technologies","volume":"158","author":"Shi","year":"2011","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib18","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1016\/j.fertnstert.2011.01.173","article-title":"Evaluation of DNA methylation status at differentially methylated regions in IVF-conceived newborn twins","volume":"95","author":"Li","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/humupd\/dms044","article-title":"Why do singletons conceived after assisted reproduction technology have adverse perinatal outcome? Systematic review and meta-analysis","volume":"19","author":"Pinborg","year":"2013","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib20","doi-asserted-by":"crossref","first-page":"3769","DOI":"10.1093\/hmg\/ddp319","article-title":"DNA methylation and gene expression differences in children conceived in\u00a0vitro or in\u00a0vivo","volume":"18","author":"Katari","year":"2009","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib21","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s13073-017-0413-5","article-title":"DNA methylation changes at infertility genes in newborn twins conceived by in\u00a0vitro fertilisation","volume":"9","author":"Castillo-Fernandez","year":"2017","journal-title":"Genome Med"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib22","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1093\/humrep\/dex209","article-title":"DNA methylation signatures in cord blood of ICSI children","volume":"32","author":"El Hajj","year":"2017","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib23","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.fertnstert.2016.05.006","article-title":"Assisted reproductive technology alters deoxyribonucleic acid methylation profiles in bloodspots of newborn infants","volume":"106","author":"Estill","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib24","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1093\/hmg\/ddy321","article-title":"Impact of assisted reproduction, infertility, sex and paternal factors on the placental DNA methylome","volume":"28","author":"Choufani","year":"2019","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib25","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1080\/15592294.2017.1336589","article-title":"Placental imprinting variation associated with assisted reproductive technologies and subfertility","volume":"12","author":"Litzky","year":"2017","journal-title":"Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib26","doi-asserted-by":"crossref","first-page":"3922","DOI":"10.1038\/s41467-019-11929-9","article-title":"Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood","volume":"10","author":"Novakovic","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib27","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1001\/jama.2014.17985","article-title":"Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection","volume":"313","author":"Boulet","year":"2015","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib28","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/ppe.12121","article-title":"Methodology for establishing a population-based birth cohort focusing on couple fertility and children's development, the Upstate KIDS Study","volume":"28","author":"Buck Louis","year":"2014","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib29","first-page":"251","article-title":"Examining infertility treatment and early childhood development in the Upstate KIDS Study","volume":"170","author":"Yeung","year":"2016","journal-title":"J Am Med Assoc Pediatr"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib30","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1093\/humrep\/dew106","article-title":"Infertility treatment and children's longitudinal growth between birth and 3 years of age","volume":"31","author":"Yeung","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib31","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/j.fertnstert.2015.02.033","article-title":"Use of assisted reproductive technology treatment as reported by mothers in comparison with registry data: the Upstate KIDS Study","volume":"103","author":"Buck Louis","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib32","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12874-016-0120-8","article-title":"Eliciting parental support for the use of newborn blood spots for pediatric research","volume":"16","author":"Yeung","year":"2016","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib33","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jim.2013.12.001","article-title":"Detection of immunoglobulin isotypes from dried blood spots","volume":"404","author":"Andersen","year":"2014","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib34","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2217\/epi-2018-0099","article-title":"Measured maternal prepregnancy anthropometry and newborn DNA methylation","volume":"11","author":"Yeung","year":"2019","journal-title":"Epigenomics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib35","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1093\/bioinformatics\/btu049","article-title":"Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays","volume":"30","author":"Aryee","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib36","doi-asserted-by":"crossref","first-page":"3740","DOI":"10.1073\/pnas.052410099","article-title":"Comprehensive analysis of CpG islands in human chromosomes 21 and 22","volume":"99","author":"Takai","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib37","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2217\/epi.12.21","article-title":"Complete pipeline for Infinium Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation","volume":"4","author":"Touleimat","year":"2012","journal-title":"Epigenomics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib38","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc B"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib39","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1080\/15592294.2016.1161875","article-title":"DNA methylation of cord blood cell types: applications for mixed cell birth studies","volume":"11","author":"Bakulski","year":"2016","journal-title":"Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib40","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s13148-019-0717-y","article-title":"Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data","volume":"11","author":"Gervin","year":"2019","journal-title":"Clin Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib41","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12859-015-0527-y","article-title":"Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective","volume":"16","author":"Houseman","year":"2015","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib42","doi-asserted-by":"crossref","first-page":"941","DOI":"10.2217\/epi-2017-0172","article-title":"Characterization of parent-of-origin methylation using the Illumina Infinium MethylationEPIC array platform","volume":"10","author":"Hernandez Mora","year":"2018","journal-title":"Epigenomics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib43","article-title":"dmrff: identifying differentially methylated regions efficiently with power and control","author":"Suderman","year":"2019","journal-title":"bioRxviv"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib44","article-title":"Perfluorooctanoic acid (PFOA) or perfluorooctane sulfonate (PFOS) and DNA methylation in newborn dried blood spots in the Upstate KIDS cohort","volume":"194","author":"Robinson","year":"2020","journal-title":"Environ Res"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/50260271-aed9-4316-b09a-304591b0cba5","article-title":"Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair","volume":"5","author":"Bolcun-Filas","year":"2009","journal-title":"PLoS Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib46","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1093\/humupd\/dmv036","article-title":"Genetics of primary ovarian insufficiency: new developments and opportunities","volume":"21","author":"Qin","year":"2015","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib47","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s10815-019-01660-1","article-title":"The second mutation of SYCE1 gene associated with autosomal recessive nonobstructive azoospermia","volume":"37","author":"Pashaei","year":"2020","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib48","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1080\/15592294.2019.1646572","article-title":"Epigenetic changes and assisted reproductive technologies","volume":"15","author":"Mani","year":"2020","journal-title":"Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib49","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1093\/humupd\/dmu033","article-title":"A systematic review and meta-analysis of DNA methylation levels and imprinting disorders in children conceived by IVF\/ICSI compared with children conceived spontaneously","volume":"20","author":"Lazaraviciute","year":"2014","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib50","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1093\/hmg\/ddn055","article-title":"Superovulation alters the expression of imprinted genes in the midgestation mouse placenta","volume":"17","author":"Fortier","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib51","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/andr.12379","article-title":"Impairment of sperm DNA methylation in male infertility: a meta-analytic study","volume":"5","author":"Santi","year":"2017","journal-title":"Andrology"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib52","doi-asserted-by":"crossref","DOI":"10.1177\/1759091416669609","article-title":"Knockdown of unconventional myosin ID expression induced morphological change in oligodendrocytes","volume":"8","author":"Yamazaki","year":"2016","journal-title":"ASN Neuro"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib53","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.juro.2012.03.047","article-title":"Genome-wide DNA methylation profiling of CpG islands in hypospadias","volume":"188","author":"Choudhry","year":"2012","journal-title":"J Urol"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib54","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1136\/jmedgenet-2013-102116","article-title":"Genome-wide DNA methylation analysis of patients with imprinting disorders identifies differentially methylated regions associated with novel candidate imprinted genes","volume":"51","author":"Docherty","year":"2014","journal-title":"J Med Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/128_2011_157","article-title":"Genetics of prion disease","volume":"305","author":"Lloyd","year":"2011","journal-title":"Top Curr Chem"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib56","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/s41588-020-0615-4","article-title":"Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes","volume":"52","author":"Cortese","year":"2020","journal-title":"Nat Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib57","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3389\/fgene.2019.00227","article-title":"Analysis of the epigenome in multiplex pre-eclampsia families identifies SORD, DGKI, and ICA1 as novel candidate risk genes","volume":"10","author":"Ariff","year":"2019","journal-title":"Front Genet"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib58","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1161\/HYPERTENSIONAHA.119.12634","article-title":"Hypertensive disorders of pregnancy and DNA methylation in newborns","volume":"74","author":"Kazmi","year":"2019","journal-title":"Hypertension"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib59","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/mp.2011.172","article-title":"Genome-wide expression profiling of schizophrenia using a large combined cohort","volume":"18","author":"Mistry","year":"2013","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib60","article-title":"A simple competing endogenous RNA network identifies novel mRNA, miRNA, and lncRNA markers in human cholangiocarcinoma","volume":"2019","author":"Zhang","year":"2019","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib61","doi-asserted-by":"crossref","first-page":"10577","DOI":"10.1038\/ncomms10577","article-title":"Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns","volume":"7","author":"Joubert","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib62","doi-asserted-by":"crossref","first-page":"474","DOI":"10.4161\/15592294.2014.988041","article-title":"Comparison of genome-wide and gene-specific DNA methylation between ART and naturally conceived pregnancies","volume":"10","author":"Melamed","year":"2015","journal-title":"Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib63","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/s11914-015-0268-x","article-title":"GNAS spectrum of disorders","volume":"13","author":"Turan","year":"2015","journal-title":"Curr Osteoporos Rep"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib64","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s13148-018-0568-y","article-title":"Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study","volume":"10","author":"Tang","year":"2018","journal-title":"Clin Epigenetics"},{"key":"10.1016\/j.fertnstert.2021.03.011_bib65","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1186\/s12881-014-0108-3","article-title":"Increased methylation at differentially methylated region of GNAS in infants born to gestational diabetes","volume":"15","author":"Chen","year":"2014","journal-title":"BMC Med Genet"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028221002168?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028221002168?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T19:27:33Z","timestamp":1777404453000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028221002168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":65,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S0015028221002168"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2021.03.011","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Conception by fertility treatment and offspring deoxyribonucleic acid methylation","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2021.03.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92021 Published by Elsevier Inc. on behalf of the American Society for Reproductive Medicine","name":"copyright","label":"Copyright"}]}}