{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T10:39:09Z","timestamp":1793529549504,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","fertstert.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Fertility and Sterility"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.fertnstert.2021.05.095","type":"journal-article","created":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T07:32:41Z","timestamp":1623483161000},"page":"1107-1116","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Medical treatment of uterine arteriovenous malformation: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"116","author":[{"given":"Adam","family":"Rosen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilson Ventura","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Matelski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ally","family":"Murji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.fertnstert.2021.05.095_bib1","first-page":"209","article-title":"Arteriovenous malformations of the uterus","volume":"73","author":"Fleming","year":"1989","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib2","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.7863\/jum.2006.25.11.1387","article-title":"Uterine arteriovenous malformations: from diagnosis to treatment","volume":"25","author":"O'Brien","year":"2006","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib3","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1177\/000331977903000111","article-title":"Congenital arteriovenous malformations involving the pelvis and retroperitoneum: a case report","volume":"30","author":"Ishikawa","year":"1979","journal-title":"Angiology"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib4","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.jmig.2012.12.008","article-title":"Prospective evaluation of the incidence of uterine vascular malformations developing after abortion or delivery","volume":"20","author":"Yazawa","year":"2013","journal-title":"J Min Invasive Gynec"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib5","first-page":"227","article-title":"Acquired uterine arteriovenous malformation - a diagnostic dilemma","volume":"89","author":"Szpera-Gozdziewicz","year":"2018","journal-title":"Ginekol Pol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib6","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1097\/01.ogx.0000183684.67656.ba","article-title":"Uterine arteriovenous malformations: a review of the current literature","volume":"60","author":"Grivell","year":"2005","journal-title":"Obstet Gynecol Surv"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib7","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1097\/01.RVI.0000096761.74047.7D","article-title":"Efficacy of embolization in traumatic uterine vascular malformations","volume":"14","author":"Ghai","year":"2003","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib8","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1097\/GCO.0b013e328338c179","article-title":"Impact of previous uterine artery embolization on fertility","volume":"22","author":"Berkane","year":"2010","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib9","first-page":"240","article-title":"Uterine artery embolization for postpartum and postabortion hemorrhage: a retrospective analysis of complications, subsequent fertility and pregnancy outcomes","volume":"38","author":"Toguchi","year":"2020","journal-title":"Jpn J Rad"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/13645706.2015.1074082","article-title":"Fertility after uterine artery embolization: a review","volume":"25","author":"McLucas","year":"2016","journal-title":"Minim Invasive Ther Allied Technol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib11","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/0029-7844(96)00122-6","article-title":"The noninvasive diagnosis and management of a uterine arteriovenous malformation","volume":"88","author":"Flynn","year":"1996","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib13","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1136\/bmjebm-2017-110853","article-title":"Methodological quality and synthesis of case series and case reports","volume":"23","author":"Murad","year":"2018","journal-title":"BMJ Evid Based Med"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib14","first-page":"228","article-title":"Management of symptomatic uterine arteriovenous malformations after gestational trophoblastic disease: the Brazilian experience and possible role for depot medroxyprogesterone acetate and tranexamic acid treatment","volume":"63","author":"Braga","year":"2018","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib15","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1111\/jog.13939","article-title":"Successful management of abnormal uterine bleeding from uterine arteriovenous malformations with progesterone in postabortal patients","volume":"45","author":"Taneja","year":"2019","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib16","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/ccr3.233","article-title":"Conservative therapy with a gonadotropin-releasing hormone agonist for a uterine arteriovenous malformation in a patient with congenital heart disease","volume":"3","author":"Katano","year":"2015","journal-title":"Clin Case Rep"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib17","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/01.AOG.0000191584.28717.2c","article-title":"Effect of gonadotropin-releasing hormone agonist on a uterine arteriovenous malformation","volume":"108","author":"Morikawa","year":"2006","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib18","first-page":"638","article-title":"Caesarean section scar pregnancy: a case series at a single tertiary centre","volume":"53","author":"Pang","year":"2012","journal-title":"Singapore Med J"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib19","doi-asserted-by":"crossref","unstructured":"Saied S. Medical treatment of uterine arteriovenous malformations: a case report. Int J Gynecol Cancer2019;29:A420.","DOI":"10.1136\/ijgc-2019-ESGO.804"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib20","first-page":"1622","article-title":"Three different clinical courses and the conservative management of uterine arteriovenous malformation (AVM) diagnosed by color Doppler ultrasonography","volume":"44","author":"Tsuzuki","year":"2018","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib21","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.jogc.2018.07.018","article-title":"Resolution of uterine arteriovenous malformation and maintenance of reproduction in 20 women treated with a GnRH agonist concomitantly with an aromatase inhibitor and tranexamic acid","volume":"41","author":"Vilos","year":"2019","journal-title":"J Obstet Gynaecol Canada"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib22","doi-asserted-by":"crossref","first-page":"137","DOI":"10.2174\/157340481102151218122925","article-title":"Medical treatment of uterine arteriovenous malformations: a case report","volume":"11","author":"Yousefi","year":"2015","journal-title":"Curr Women's Health Rev"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib23","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1590\/S0100-39842014000200016","article-title":"Radiological findings of uterine arteriovenous malformation: a case report of an unusual and life-threatening cause of abnormal vaginal bleeding","volume":"47","author":"Farias","year":"2014","journal-title":"Radi Brasil"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib24","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.tjog.2014.06.008","article-title":"Acquired uterine vascular abnormalities associated with persistent human chorionic gonadotropin: experience at a Korean teaching hospital","volume":"54","author":"Ju","year":"2015","journal-title":"Taiwanese J Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib25","first-page":"81","article-title":"Conservative management of cesarean scar pregnancy with uterine arteriovenous malformation: a case report","volume":"58","author":"Kochhar","year":"2013","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib26","first-page":"12","article-title":"Failed angiographic embolization in uterine arteriovenous malformation: A case report and review of the literature","volume":"10","author":"Bagga","year":"2008","journal-title":"Medscape J Med"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib27","first-page":"453","article-title":"Acquired uterine arteriovenous fistulas after choriocarcinoma. A case report","volume":"19","author":"Delaloye","year":"1998","journal-title":"Eur J Gynaec Oncol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib28","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1479-828X.1999.tb03424.x","article-title":"Medical treatment of a uterine arteriovenous malformation","volume":"39","author":"Khatree","year":"1999","journal-title":"Aust New Zeal J Obstet Gynaecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib29","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1111\/jog.12370","article-title":"Disappearance of a uterine arteriovenous malformation following long-term administration of oral norgestrel\/ethinyl estradiol","volume":"40","author":"Oride","year":"2014","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib30","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1016\/j.fertnstert.2008.01.097","article-title":"Conservative management of large uterine arteriovenous malformation: case report","volume":"90","author":"Rosa","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1177\/875647930201800105","article-title":"Uterine arteriovenous malformation: sonographic diagnosis in a patient presenting with heavy postpartum vaginal bleeding","volume":"18","author":"Sulzdorf","year":"2002","journal-title":"J Diagn Medical Sonogr"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib32","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s10397-009-0503-5","article-title":"Fertility and pregnancy outcomes following uterine artery embolization (UAE) for uterine arteriovenous malformation (AVM)","volume":"7","author":"Vilos","year":"2010","journal-title":"Gynecol Surg"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib33","first-page":"961","article-title":"Pregnancy after medical management of a uterine arteriovenous malformation. A case report","volume":"45","author":"Goldberg","year":"2000","journal-title":"J Reprod Med"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib34","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1034\/j.1600-0412.2001.801216.x","article-title":"Successful pregnancy after the noninvasive management of uterine arteriovenous malformation","volume":"80","author":"Onoyama","year":"2001","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib35","first-page":"843","article-title":"Successful medical treatment with danazol after failed embolization of uterine arteriovenous malformation","volume":"102","author":"Takeuchi","year":"2003","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib36","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.gmit.2015.10.001","article-title":"A case of severe uterine arteriovenous malformation treated with danazol followed by a transarterial embolization of unilateral uterine and ovarian arteries","volume":"4","author":"Yazawa","year":"2015","journal-title":"Gynecol Min Invasive There"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib37","first-page":"58","article-title":"Fertility preserving management of uterine arteriovenous malformations","volume":"125","author":"Dwivedee","year":"2018","journal-title":"BJOG"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib38","first-page":"61","article-title":"Uterine arteriovenous malformation - Life threatening emergency in young women","volume":"125","author":"Hammad","year":"2018","journal-title":"BJOG"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib39","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2013-009489","article-title":"Acquired vascular malformation in ruptured caesarean section scar: a rare cause of life-threatening vaginal bleeding","volume":"2013","author":"Hilal","year":"2013","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib40","doi-asserted-by":"crossref","first-page":"6437670","DOI":"10.1155\/2017\/6437670","article-title":"Spontaneous regression of uterine arteriovenous malformations with conservative management","volume":"2017","author":"Mekaru","year":"2017","journal-title":"Case Rep Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib41","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/AOG.0b013e3181f7381f","article-title":"Resolution of uterine arteriovenous malformation and successful pregnancy after treatment with a gonadotropin-releasing hormone agonist","volume":"117","author":"Nonaka","year":"2011","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib42","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jpag.2018.02.065","article-title":"Conservative management of uterine arteriovenous malformation during adolescence","volume":"31","author":"Richards","year":"2018","journal-title":"J Pedicle Adolesc Gynecol"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib43","first-page":"208","article-title":"Uterine arteriovenous malformation: An alternative for conservative management. Case report and literature review","volume":"86","author":"Fugarolas-Marin","year":"2018","journal-title":"Ginecol Obstet Mexico"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib44","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1055\/s-0035-1563721","article-title":"A systematic review of acquired uterine arteriovenous malformations: pathophysiology, diagnosis, and transcatheter treatment","volume":"6","author":"Yoon","year":"2015","journal-title":"AJP Rep"},{"key":"10.1016\/j.fertnstert.2021.05.095_bib45","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1007\/s00404-011-2067-7","article-title":"Uterine arteriovenous malformations induced after diagnostic curettage: a systematic review","volume":"284","author":"Peitsidis","year":"2011","journal-title":"Arch Gynecol Obstet"}],"container-title":["Fertility and Sterility"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028221004489?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0015028221004489?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T08:33:14Z","timestamp":1758011594000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0015028221004489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S0015028221004489"],"URL":"https:\/\/doi.org\/10.1016\/j.fertnstert.2021.05.095","relation":{},"ISSN":["0015-0282"],"issn-type":[{"value":"0015-0282","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Medical treatment of uterine arteriovenous malformation: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Fertility and Sterility","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.fertnstert.2021.05.095","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a92021 American Society for Reproductive Medicine, Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}